메뉴 건너뛰기




Volumn 16, Issue 1, 1996, Pages 53-65

Effects of reverse transcriptase inhibitors on telomere Length and telomerase activity in two immortalized human cell lines

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA;

EID: 0029655485     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.1.53     Document Type: Article
Times cited : (358)

References (49)
  • 3
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • Blackburn, E. H. 1991 Structure and function of telomeres Nature (London) 350:569-573.
    • (1991) Nature (London) , vol.350 , pp. 569-573
    • Blackburn, E.H.1
  • 4
    • 0010526741 scopus 로고
    • Telomerase
    • R. F. Gesteland and J. F. Atkins (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Blackburn, E. H. 1993 Telomerase. p. 557-576. In R. F. Gesteland and J. F. Atkins (ed.), The RNA world. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1993) The RNA World , pp. 557-576
    • Blackburn, E.H.1
  • 5
    • 0028305614 scopus 로고
    • Telomeres. no end in sight
    • Blackburn, E. H. 1994 Telomeres. no end in sight. Cell 77:621-623.
    • (1994) Cell , vol.77 , pp. 621-623
    • Blackburn, E.H.1
  • 6
    • 0019522449 scopus 로고
    • Non-nucleosomal packaging of a landemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena
    • Blackburn, E. H., and S.-S. Chiou. 1981 Non-nucleosomal packaging of a landemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena. Proc Natl Acad. Sci USA 78:2263-2267.
    • (1981) Proc Natl Acad. Sci USA , vol.78 , pp. 2263-2267
    • Blackburn, E.H.1    Chiou, S.-S.2
  • 7
    • 0029066169 scopus 로고
    • Telomerase activity in normal and malignant hematopoietic cells
    • Broccoli, D., J. W. Young, and T. De Lange. 1995. Telomerase activity in normal and malignant hematopoietic cells Proc Natl. Acad. Sci. USA 92: 9082-9086.
    • (1995) Proc Natl. Acad. Sci. USA , vol.92 , pp. 9082-9086
    • Broccoli, D.1    Young, J.W.2    De Lange, T.3
  • 9
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter, C. M., A. A. Avilion, C. E. LeFeuvre, N. G. Stewart, C. W. Greider, C. B. Harley, and S. Bacchetti. 1992. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11:1921-1929
    • (1992) EMBO J. , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 11
    • 0028201293 scopus 로고
    • Activation of telomerase in a human tumor
    • de Lange, T. 1994. Activation of telomerase in a human tumor. Proc. Natl. Acad. Sci USA 91:2882-2885.
    • (1994) Proc. Natl. Acad. Sci USA , vol.91 , pp. 2882-2885
    • De Lange, T.1
  • 13
    • 0029655261 scopus 로고    scopus 로고
    • Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase
    • Gilley, D., and E. H. Blackburn. 1996. Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase. Mol Cell. Biol. 16:66-75.
    • (1996) Mol Cell. Biol. , vol.16 , pp. 66-75
    • Gilley, D.1    Blackburn, E.H.2
  • 14
    • 0029144984 scopus 로고
    • Telomerase RNA residues play critical roles in active site function
    • Gilley, D., M. S. Lee, and E. H. Blackburn. 1995. Telomerase RNA residues play critical roles in active site function. Genes Dev. 9:2214-2226.
    • (1995) Genes Dev. , vol.9 , pp. 2214-2226
    • Gilley, D.1    Lee, M.S.2    Blackburn, E.H.3
  • 15
    • 0023037564 scopus 로고
    • Telomere proteins: Specific recognition and protection of the natural termini of Oxytricha macronuclear DNA
    • Gottschling, D. E., and V. A. Zakian. 1986. Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA Cell 47:195-205.
    • (1986) Cell , vol.47 , pp. 195-205
    • Gottschling, D.E.1    Zakian, V.A.2
  • 16
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity n Tetrahymena extracts
    • Greider, C. W., and E. H. Blackburn. 1985 Identification of a specific telomere terminal transferase activity n Tetrahymena extracts. Cell 43:405-413
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 17
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • Greider, C. W., and E. H. Blackburn. 1989. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature (London) 337:331-337.
    • (1989) Nature (London) , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 18
    • 0024146519 scopus 로고
    • Maintenance of multiplication rate stability by cell populations in the face of heterogeneity among individual cells
    • Grundel, R., and H. Rubin. 1988. Maintenance of multiplication rate stability by cell populations in the face of heterogeneity among individual cells. J. Cell Sci 91:571-576.
    • (1988) J. Cell Sci , vol.91 , pp. 571-576
    • Grundel, R.1    Rubin, H.2
  • 19
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley, C. B., A. B. Futcher, and C. W. Greider. 1990 Telomeres shorten during ageing of human fibroblasts. Nature (London) 345:458-460
    • (1990) Nature (London) , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 25
    • 0028140264 scopus 로고
    • Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells
    • Klingelhutz, A. J., S. A. Barber, P. P. Smith, K. Dyer, and J. K. McDougall. 1994 Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells. Mol Cell Biol. 14:961-969
    • (1994) Mol Cell Biol. , vol.14 , pp. 961-969
    • Klingelhutz, A.J.1    Barber, S.A.2    Smith, P.P.3    Dyer, K.4    McDougall, J.K.5
  • 26
    • 0000456849 scopus 로고
    • Inhibitors of HIV reverse transcriptase as antiviral agents and drug resistance
    • A. M. Skalka and S P. Goff (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N Y
    • Larder, B. A. 1993 Inhibitors of HIV reverse transcriptase as antiviral agents and drug resistance, p. 205-222. In A. M. Skalka and S P. Goff (ed.), Reverse transcriptase. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N Y.
    • (1993) Reverse Transcriptase , pp. 205-222
    • Larder, B.A.1
  • 27
    • 0023669250 scopus 로고
    • Dynamics of telomere length variation in Tetrahymena
    • Larson, D. D., E. A. Spangler, and E. H. Blackburn. 1987. Dynamics of telomere length variation in Tetrahymena Cell 50:477-483
    • (1987) Cell , vol.50 , pp. 477-483
    • Larson, D.D.1    Spangler, E.A.2    Blackburn, E.H.3
  • 30
    • 0024973811 scopus 로고
    • A mutant with a defect in telomere elongation leads to senescence in yeast
    • Lundblad, V., and J. W. Szostak. 1989. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 57:633-643
    • (1989) Cell , vol.57 , pp. 633-643
    • Lundblad, V.1    Szostak, J.W.2
  • 31
    • 0016732572 scopus 로고
    • Terminal deoxynucleotidyl transferase activity in human leukemic cells and in normal human thymocytes
    • McCaffrey, R., T. A. Harrison, R. Parkman, and D. Baltimore. 1975. Terminal deoxynucleotidyl transferase activity in human leukemic cells and in normal human thymocytes N. Engl. J. Med 292:775-780.
    • (1975) N. Engl. J. Med , vol.292 , pp. 775-780
    • McCaffrey, R.1    Harrison, T.A.2    Parkman, R.3    Baltimore, D.4
  • 32
    • 0000075523 scopus 로고
    • The behavior of successive nuclear divisions of a chromosome broken at meiosis
    • McClintock, B. 1939. The behavior of successive nuclear divisions of a chromosome broken at meiosis. Proc Natl. Acad. Sci. USA 25:405-416.
    • (1939) Proc Natl. Acad. Sci. USA , vol.25 , pp. 405-416
    • McClintock, B.1
  • 33
    • 0029102354 scopus 로고
    • Runaway telomeres in telomerase RNA gene mutants of Kluyveromyces lactis
    • McEachern, M., and E. H. Blackburn. 1995 Runaway telomeres in telomerase RNA gene mutants of Kluyveromyces lactis. Nature (London) 276: 403-409
    • (1995) Nature (London) , vol.276 , pp. 403-409
    • McEachern, M.1    Blackburn, E.H.2
  • 35
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • Morin, G. B. 1989. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59:521-529.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 37
    • 0028007237 scopus 로고
    • Telomere dynamics in an immortal human cell line
    • Murnane, J. P., L. Sabatie, B. A. Marder, and W. F. Morgan. 1994. Telomere dynamics in an immortal human cell line. EMBO J. 13:4953-4962.
    • (1994) EMBO J. , vol.13 , pp. 4953-4962
    • Murnane, J.P.1    Sabatie, L.2    Marder, B.A.3    Morgan, W.F.4
  • 38
    • 0027956728 scopus 로고
    • Telomerase activity in vivo in human malignant hematopoietic cells
    • Nilsson, P., C. Mehle, K. Remes, and G. Roos. 1994. Telomerase activity in vivo in human malignant hematopoietic cells. Oncogene 9:3043-3048.
    • (1994) Oncogene , vol.9 , pp. 3043-3048
    • Nilsson, P.1    Mehle, C.2    Remes, K.3    Roos, G.4
  • 39
    • 0029040101 scopus 로고
    • Developmental and tissue specific regulation of mouse telomerase and telomere length
    • Prowse, K. R., and C. W. Greider. 1995. Developmental and tissue specific regulation of mouse telomerase and telomere length. Proc Natl Acad. Sci. USA 92:4818-4822.
    • (1995) Proc Natl Acad. Sci. USA , vol.92 , pp. 4818-4822
    • Prowse, K.R.1    Greider, C.W.2
  • 40
    • 0028090125 scopus 로고
    • Two human breast cancer cell lines showing decreasing telomeric repeat length during early in vitro passaging
    • Rogalla, P., B. Kazmierczak, C. Rohen, G. Trams, S. Bartnitzke, and J. Bullerdiek. 1994. Two human breast cancer cell lines showing decreasing telomeric repeat length during early in vitro passaging Cancer Genet. Cytogenet. 77:19-25.
    • (1994) Cancer Genet. Cytogenet. , vol.77 , pp. 19-25
    • Rogalla, P.1    Kazmierczak, B.2    Rohen, C.3    Trams, G.4    Bartnitzke, S.5    Bullerdiek, J.6
  • 42
    • 0028089923 scopus 로고
    • Telomere length variation in normal and malignant human tissues
    • Schmitt, H., N. Blin, H. Zankl, and H. Scherthan. 1994 Telomere length variation in normal and malignant human tissues. Genes Chromosomes Cancer 11:171-177.
    • (1994) Genes Chromosomes Cancer , vol.11 , pp. 171-177
    • Schmitt, H.1    Blin, N.2    Zankl, H.3    Scherthan, H.4
  • 43
    • 0025021235 scopus 로고
    • Functional evidence for an RNA template in telomerase
    • Shippen-Lentz, D., and E. H. Blackburn. 1990. Functional evidence for an RNA template in telomerase Science 247:546-552.
    • (1990) Science , vol.247 , pp. 546-552
    • Shippen-Lentz, D.1    Blackburn, E.H.2
  • 44
    • 0027944347 scopus 로고
    • - template RNA component of Saccharomyces cerevisiae telomerase
    • - template RNA component of Saccharomyces cerevisiae telomerase. Science 266:404-409.
    • (1994) Science , vol.266 , pp. 404-409
    • Singer, M.S.1    Gottschling, D.E.2
  • 45
    • 0028222581 scopus 로고
    • The effects of nucleobide analogs on telomerase and telomeres in Tetrahymena
    • Strahl, C., and E. H. Blackburn. 1994. The effects of nucleobide analogs on telomerase and telomeres in Tetrahymena. Nucleic Acids Res. 22:893-900
    • (1994) Nucleic Acids Res. , vol.22 , pp. 893-900
    • Strahl, C.1    Blackburn, E.H.2
  • 46
    • 0007530695 scopus 로고
    • Genetic control of chromosome length in yeast
    • Walmsley, R. M., and T. D. Petes. 1985. Genetic control of chromosome length in yeast. Proc. Natl Acad. Sci. USA 82:506-510.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 506-510
    • Walmsley, R.M.1    Petes, T.D.2
  • 47
    • 0025351383 scopus 로고
    • Telomere-telomere recombination provides an express pathway for telomere acquisition
    • Wang, S.-S., and V. A. Zakian. 1990. Telomere-telomere recombination provides an express pathway for telomere acquisition. Nature (London) 345: 456-458.
    • (1990) Nature (London) , vol.345 , pp. 456-458
    • Wang, S.-S.1    Zakian, V.A.2
  • 49
    • 0025279059 scopus 로고
    • In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
    • Yu, G., J. D. Bradley, L. D. Attardi, and E. H. Blackburn. 1990. In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature (London) 344:126-131.
    • (1990) Nature (London) , vol.344 , pp. 126-131
    • Yu, G.1    Bradley, J.D.2    Attardi, L.D.3    Blackburn, E.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.