Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia

Molecular Psychiatry

Volumn 6, Issue 2, 2001, Pages 173-178

  Millar, J K ^a,b   Christie, S ^a,b   Anderson, S ^a,b   Lawson, D ^a,b   Loh, D Hsiao Wei ^a,b   Devon, R S ^a,b   Arveiler, B ^c   Muir, W J ^a,b,d   Blackwood, D H R ^a,b,d   Porteous, D J ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d ROYAL EDINBURGH HOSPITAL   (United Kingdom)

Author keywords

AT AC intron; DISC1; DISC2; Schizophrenia

Indexed keywords

DNA POLYMERASE;

ARTICLE; CELL CULTURE; CHROMOSOME 1; CHROMOSOME TRANSLOCATION 1; COSMID; DISRUPTED IN SCHIZOPHRENIA 1 GENE; DISRUPTED IN SCHIZOPHRENIA 2 GENE; DNA SEQUENCE; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE DISRUPTION; GENE LIBRARY; GENE LOCATION; GENE MAPPING; GENE SEGREGATION; GENETIC LINKAGE; GENOME; HUMAN; INTRON; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

CELL LINE; GENETIC MARKERS; GENOME, HUMAN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; LINKAGE (GENETICS); MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; RNA SPLICE SITES; SCHIZOPHRENIA; TRANSLOCATION, GENETIC;

EID: 17744391567     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000784     Document Type: Article

References (20)

1. Genetic basis of schizophrenia
2. Association within a family of a balanced translocation with major mental illness
3. Novel transcribed sequences neighbouring a translocation breakpoint associated with schizophrenia
4. A long-range restriction map across 3Mb of the chromosome 11 breakpoint region of a translocation linked to schizophrenia: Localisation of the breakpoint and the search for neighbouring genes
5. Physical mapping of a glutamate receptor gene in relation to a balanced translocation associated with schizophrenia in a large Scottish family
6. Disruption of two novel genes by a translocation cosegregating with schizophrenia
7. Naturally occuring antisense RNA
8. Regulation of gene expression by natural antisense RNA transcripts
9. Imprinting mechanisms
10. Construction of bacterial artificial chromosome libraries using the modified P1 (PAC) System
11. Schizophrenia-associated chromosome 11q21 translocation: Identification of flanking markers and development of chromosome 11q fragment hybrids as cloning and mapping resources
12. A contiguous clone map over 3 Mb on the long arm of chromosome 11 across a balanced translocation associated with schizophrenia
13. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
14. Pre-mRNA splicing: The discovery of a new spliceosome doubles the challenge
15. Genome-wide scan for schizophrenia in the Finnish population: Evidence for a locus on chromosome 7q22
16. Linkage analysis of fifty-seven microsatellite loci to bipolar disorder
17. A follow-up report of a genome search for affective disorder predisposition loci in the Old Order Amish
18. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2
19. A genome wide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci