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Volumn 81, Issue 1, 2003, Pages 67-77

Evolutionary constraints on the Disrupted in Schizophrenia locus

Author keywords

Alternative splicing; DNA, intergenic; Genetic predisposition to disease; Genomics; Mental disorders; RNA splice sites; Schizophrenia; Synteny; Translocation (genetics)

Indexed keywords

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; GENE LOCUS; GENE SEQUENCE; GENE STRUCTURE; GENETIC CODE; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; GENOMICS; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; MAMMAL; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PUFFER FISH; SCHIZOPHRENIA; ZEBRA FISH;

EID: 0037289166     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0888-7543(02)00026-5     Document Type: Article
Times cited : (82)

References (38)
  • 2
    • 0034535747 scopus 로고    scopus 로고
    • The genetic epidemiology of schizophrenia and of schizophrenia spectrum disorders
    • Lichtermann D., Karbe E., Maier W. The genetic epidemiology of schizophrenia and of schizophrenia spectrum disorders. Eur. Arch. Psychiatry Clin. Neurosci. 250:2000;304-310.
    • (2000) Eur. Arch. Psychiatry Clin. Neurosci. , vol.250 , pp. 304-310
    • Lichtermann, D.1    Karbe, E.2    Maier, W.3
  • 3
    • 0035060793 scopus 로고    scopus 로고
    • Nuts and bolts of psychiatric genetics: Building on the Human Genome Project
    • Evans K.L., Muir W.J., Blackwood D.H., Porteous D.J. Nuts and bolts of psychiatric genetics building on the Human Genome Project . Trends Genet. 17:2001;34-40.
    • (2001) Trends Genet. , vol.17 , pp. 34-40
    • Evans, K.L.1    Muir, W.J.2    Blackwood, D.H.3    Porteous, D.J.4
  • 4
    • 0025277392 scopus 로고
    • Association within a family of a balanced autosomal translocation with major mental illness
    • St Clair D., et al. Association within a family of a balanced autosomal translocation with major mental illness. Lancet. 336:1990;13-16.
    • (1990) Lancet , vol.336 , pp. 13-16
    • St Clair, D.1
  • 5
    • 0034927864 scopus 로고    scopus 로고
    • Schizophrenia and affective disorders - Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family
    • Blackwood D.H., et al. Schizophrenia and affective disorders - cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes clinical and P300 findings in a family . Am. J. Hum. Genet. 69:2001;428-433.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 428-433
    • Blackwood, D.H.1
  • 6
    • 0035878561 scopus 로고    scopus 로고
    • Chromosome 1 loci in Finnish schizophrenia families
    • Ekelund J., et al. Chromosome 1 loci in Finnish schizophrenia families. Hum. Mol. Genet. 10:2001;1611-1617.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1611-1617
    • Ekelund, J.1
  • 7
    • 0035309305 scopus 로고    scopus 로고
    • Identification of genes from a schizophrenia-linked translocation breakpoint region
    • doi:10.1006/geno.2001.6516
    • Semple C.A., Devon R.S., Le Hellard S., Porteous D.J. Identification of genes from a schizophrenia-linked translocation breakpoint region. Genomics. 73:2001;123-126. doi:10.1006/geno.2001.6516.
    • (2001) Genomics , vol.73 , pp. 123-126
    • Semple, C.A.1    Devon, R.S.2    Le Hellard, S.3    Porteous, D.J.4
  • 8
    • 0034702026 scopus 로고    scopus 로고
    • Disruption of two novel genes by a translocation co-segregating with schizophrenia
    • Millar J.K., et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum. Mol. Genet. 9:2000;1415-1423.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1415-1423
    • Millar, J.K.1
  • 9
    • 0035812318 scopus 로고    scopus 로고
    • Characterization and comparative analysis of the EGLN gene family
    • Taylor M.S. Characterization and comparative analysis of the EGLN gene family. Gene. 275:2001;125-132.
    • (2001) Gene , vol.275 , pp. 125-132
    • Taylor, M.S.1
  • 10
    • 17944375360 scopus 로고    scopus 로고
    • C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
    • Epstein A.C., et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell. 107:2001;43-54.
    • (2001) Cell , vol.107 , pp. 43-54
    • Epstein, A.C.1
  • 11
    • 0033066605 scopus 로고    scopus 로고
    • Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons
    • Lipscomb E.A., Sarmiere P.D., Crowder R.J., Freeman R.S. Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons. J. Neurochem. 73:1999;429-432.
    • (1999) J. Neurochem. , vol.73 , pp. 429-432
    • Lipscomb, E.A.1    Sarmiere, P.D.2    Crowder, R.J.3    Freeman, R.S.4
  • 12
    • 0035895928 scopus 로고    scopus 로고
    • SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons
    • Lipscomb E.A., Sarmiere P.D., Freeman R.S. SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons. J. Biol. Chem. 276:2001;5085-5092.
    • (2001) J. Biol. Chem. , vol.276 , pp. 5085-5092
    • Lipscomb, E.A.1    Sarmiere, P.D.2    Freeman, R.S.3
  • 13
    • 0034003647 scopus 로고    scopus 로고
    • Mouse testis brain ribonucleic acid-binding protein/translin colocalizes with microtubules and is immunoprecipitated with messenger ribonucleic acids encoding myelin basic protein, alpha calmodulin kinase II, and protamines 1 and 2
    • Wu X.Q., Hecht N.B. Mouse testis brain ribonucleic acid-binding protein/translin colocalizes with microtubules and is immunoprecipitated with messenger ribonucleic acids encoding myelin basic protein, alpha calmodulin kinase II, and protamines 1 and 2. Biol. Reprod. 62:2000;720-725.
    • (2000) Biol. Reprod. , vol.62 , pp. 720-725
    • Wu, X.Q.1    Hecht, N.B.2
  • 14
    • 0031023837 scopus 로고    scopus 로고
    • Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX
    • Aoki K., Ishida R., Kasai M. Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX. FEBS Lett. 401:1997;109-112.
    • (1997) FEBS Lett. , vol.401 , pp. 109-112
    • Aoki, K.1    Ishida, R.2    Kasai, M.3
  • 15
    • 0034235003 scopus 로고    scopus 로고
    • Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia
    • doi:10.1006/geno.2000.6239
    • Millar J.K., Christie S., Semple C.A., Porteous D.J. Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia. Genomics. 67:2000;69-77. doi:10.1006/geno.2000.6239.
    • (2000) Genomics , vol.67 , pp. 69-77
    • Millar, J.K.1    Christie, S.2    Semple, C.A.3    Porteous, D.J.4
  • 16
    • 0027507739 scopus 로고
    • Characterization of the pufferfish (F. rubripes) genome as a compact model vertebrate genome
    • Brenner S., et al. Characterization of the pufferfish (F. rubripes) genome as a compact model vertebrate genome. Nature. 366:1993;265-268.
    • (1993) Nature , vol.366 , pp. 265-268
    • Brenner, S.1
  • 17
    • 0032580152 scopus 로고    scopus 로고
    • A molecular timescale for vertebrate evolution
    • Kumar S., Hedges S.B. A molecular timescale for vertebrate evolution. Nature. 392:1998;917-920.
    • (1998) Nature , vol.392 , pp. 917-920
    • Kumar, S.1    Hedges, S.B.2
  • 18
    • 0024392784 scopus 로고
    • Human nidogen: CDNA cloning, cellular expression, and mapping of the gene to chromosome Iq43
    • Olsen D.R., et al. Human nidogen cDNA cloning, cellular expression, and mapping of the gene to chromosome Iq43 . Am. J. Hum. Genet. 44:1989;876-885.
    • (1989) Am. J. Hum. Genet. , vol.44 , pp. 876-885
    • Olsen, D.R.1
  • 19
    • 0032573059 scopus 로고    scopus 로고
    • Complete sequencing of the F. rubripes WAGR region from WT1 to PAX6: Dramatic compaction and conservation of synteny with human chromosome 11p13
    • Miles C., et al. Complete sequencing of the F. rubripes WAGR region from WT1 to PAX6 dramatic compaction and conservation of synteny with human chromosome 11p13 . Proc. Natl. Acad. Sci. USA. 95:1998;13068-13072.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13068-13072
    • Miles, C.1
  • 20
    • 0033828441 scopus 로고    scopus 로고
    • Genomic sequence analysis of F. rubripes rubripes CFTR and flanking genes in a 60 kb region conserving synteny with 800 kb of human chromosome 7
    • Davidson H., Taylor M.S., Doherty A., Boyd A.C., Porteous D.J. Genomic sequence analysis of F. rubripes rubripes CFTR and flanking genes in a 60 kb region conserving synteny with 800 kb of human chromosome 7. Genome Res. 10:2000;1194-1203.
    • (2000) Genome Res. , vol.10 , pp. 1194-1203
    • Davidson, H.1    Taylor, M.S.2    Doherty, A.3    Boyd, A.C.4    Porteous, D.J.5
  • 21
    • 0034667983 scopus 로고    scopus 로고
    • Identification and characterization of a beta proteasome subunit cluster in the Japanese pufferfish (F. rubripes rubripes)
    • Clark M.S., Pontarotti P., Gilles A., Kelly A., Elgar G. Identification and characterization of a beta proteasome subunit cluster in the Japanese pufferfish (F. rubripes rubripes). J. Immunol. 165:2000;4446-4452.
    • (2000) J. Immunol. , vol.165 , pp. 4446-4452
    • Clark, M.S.1    Pontarotti, P.2    Gilles, A.3    Kelly, A.4    Elgar, G.5
  • 22
    • 0034110195 scopus 로고    scopus 로고
    • Isolation and characterization of the mouse translin-associated protein X (TSNAX) gene
    • Devon R.S., Taylor M.S., Millar J.K., Porteous D.J. Isolation and characterization of the mouse translin-associated protein X (TSNAX) gene. Mamm. Genome. 11:2000;395-398.
    • (2000) Mamm. Genome. , vol.11 , pp. 395-398
    • Devon, R.S.1    Taylor, M.S.2    Millar, J.K.3    Porteous, D.J.4
  • 23
    • 0034331073 scopus 로고    scopus 로고
    • Finding nuclear localization signals
    • Cokol M., Nair R., Rost B. Finding nuclear localization signals. EMBO Rep. 1:2000;411-415.
    • (2000) EMBO Rep. , vol.1 , pp. 411-415
    • Cokol, M.1    Nair, R.2    Rost, B.3
  • 24
    • 0032077533 scopus 로고    scopus 로고
    • Using neural networks for prediction of the subcellular location of proteins
    • Reinhardt A., Hubbard T. Using neural networks for prediction of the subcellular location of proteins. Nucleic Acids Res. 26:1998;2230-2236.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2230-2236
    • Reinhardt, A.1    Hubbard, T.2
  • 25
    • 0029889988 scopus 로고    scopus 로고
    • PHD: Predicting one-dimensional protein structure by profile based neural networks
    • Rost B. PHD predicting one-dimensional protein structure by profile based neural networks . Methods Enzymol. 266:1996;525-539.
    • (1996) Methods Enzymol. , vol.266 , pp. 525-539
    • Rost, B.1
  • 26
    • 0029999370 scopus 로고    scopus 로고
    • Gain of Sp1 sites and loss of repressor sequences associated with a young, transcriptionally active subset of HERV-H endogenous long terminal repeats
    • Nelson D.T., Goodchild N.L., Mager D.L. Gain of Sp1 sites and loss of repressor sequences associated with a young, transcriptionally active subset of HERV-H endogenous long terminal repeats. Virology. 220:1996;213-218.
    • (1996) Virology , vol.220 , pp. 213-218
    • Nelson, D.T.1    Goodchild, N.L.2    Mager, D.L.3
  • 27
    • 0034682079 scopus 로고    scopus 로고
    • Differences in HERV-K LTR insertions in orthologous loci of humans and great apes
    • Lebedev Y.B., et al. Differences in HERV-K LTR insertions in orthologous loci of humans and great apes. Gene. 247:2000;265-277.
    • (2000) Gene , vol.247 , pp. 265-277
    • Lebedev, Y.B.1
  • 28
    • 0031797726 scopus 로고    scopus 로고
    • Human-specific integrations of the HERV-K endogenous retrovirus family
    • Medstrand P., Mager D.L. Human-specific integrations of the HERV-K endogenous retrovirus family. J. Virol. 72:1998;9782-9787.
    • (1998) J. Virol. , vol.72 , pp. 9782-9787
    • Medstrand, P.1    Mager, D.L.2
  • 29
    • 0032247416 scopus 로고    scopus 로고
    • Evolutionary fates and origins of U12-type introns
    • Burge C.B., Padgett R.A., Sharp P.A. Evolutionary fates and origins of U12-type introns. Mol. Cell. 2:1998;773-785.
    • (1998) Mol. Cell , vol.2 , pp. 773-785
    • Burge, C.B.1    Padgett, R.A.2    Sharp, P.A.3
  • 31
    • 0031955518 scopus 로고    scopus 로고
    • Base-calling of automated sequencer traces using phred. I. Accuracy assessment
    • Ewing B., Hillier L., Wendl M.C., Green P. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8:1998;175-185.
    • (1998) Genome Res. , vol.8 , pp. 175-185
    • Ewing, B.1    Hillier, L.2    Wendl, M.C.3    Green, P.4
  • 32
    • 0036119466 scopus 로고    scopus 로고
    • Computational comparison of human genomic sequence assemblies for a region of chromosome 4
    • Semple C.A., Morris S.W., Porteous D.J., Evans K.L. Computational comparison of human genomic sequence assemblies for a region of chromosome 4. Genome Res. 12:2002;424-429.
    • (2002) Genome Res. , vol.12 , pp. 424-429
    • Semple, C.A.1    Morris, S.W.2    Porteous, D.J.3    Evans, K.L.4
  • 33
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • Altschul S.F., et al. Gapped BLAST and PSI-BLAST a new generation of protein database search programs . Nucleic Acids Res. 25:1997;3389-3402.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3389-3402
    • Altschul, S.F.1
  • 34
    • 0031586003 scopus 로고    scopus 로고
    • Prediction of complete gene structures in human genomic DNA
    • doi:10.1006/jmbi.1997.0951
    • Burge C., Karlin S. Prediction of complete gene structures in human genomic DNA. J. Mol. Biol. 268:1997;78-94. doi:10.1006/jmbi.1997.0951.
    • (1997) J. Mol. Biol. , vol.268 , pp. 78-94
    • Burge, C.1    Karlin, S.2
  • 35
    • 0031732094 scopus 로고    scopus 로고
    • A computer program for aligning a cDNA sequence with a genomic DNA sequence
    • Florea L., Hartzell G., Zhang Z., Rubin G.M., Miller W. A computer program for aligning a cDNA sequence with a genomic DNA sequence. Genome Res. 8:1998;967-974.
    • (1998) Genome Res. , vol.8 , pp. 967-974
    • Florea, L.1    Hartzell, G.2    Zhang, Z.3    Rubin, G.M.4    Miller, W.5
  • 36
    • 0034020416 scopus 로고    scopus 로고
    • PipMaker - A web server for aligning two genomic DNA sequences
    • Schwartz S., et al. PipMaker - A web server for aligning two genomic DNA sequences. Genome Res. 10:2000;577-586.
    • (2000) Genome Res. , vol.10 , pp. 577-586
    • Schwartz, S.1
  • 37
    • 0034518158 scopus 로고    scopus 로고
    • VISTA: Visualizing Global DNA Sequence Alignments of Arbitrary Length
    • Mayor C., et al. VISTA Visualizing Global DNA Sequence Alignments of Arbitrary Length . Bioinformatics. 16:2000;1046-1047.
    • (2000) Bioinformatics , vol.16 , pp. 1046-1047
    • Mayor, C.1


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