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Volumn 26, Issue 1, 2006, Pages 23-42

Recombination in the human IGK locus

Author keywords

Allelic exclusion; Deletion; Gene rearrangement; IGK locus; V(D)J recombination

Indexed keywords

IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN;

EID: 33745193506     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (105)
  • 1
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa S. Somatic generation of antibody diversity. Nature. 1983;302:575-81.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 2
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
    • Lewis SM. The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses. Adv Immunol. 1994;56:27-150.
    • (1994) Adv Immunol , vol.56 , pp. 27-150
    • Lewis, S.M.1
  • 3
    • 0024846088 scopus 로고
    • The V(D)J recombination activating gene, RAG-1
    • Schatz DG, Oettinger MA, Baltimore D. The V(D)J recombination activating gene, RAG-1. Cell. 1989;59:1035-48.
    • (1989) Cell , vol.59 , pp. 1035-1048
    • Schatz, D.G.1    Oettinger, M.A.2    Baltimore, D.3
  • 4
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger MA, Schatz DG, Gorka C, Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science. 1990;248:1517-23.
    • (1990) Science , vol.248 , pp. 1517-1523
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.4
  • 6
    • 0027688019 scopus 로고
    • The variable genes of the human immunoglobulin kappa locus
    • Schable KF, Zachau HG. The variable genes of the human immunoglobulin kappa locus. Biol Chem Hoppe Seyler. 1993;374:1001-22.
    • (1993) Biol Chem Hoppe Seyler , vol.374 , pp. 1001-1022
    • Schable, K.F.1    Zachau, H.G.2
  • 8
    • 0027197045 scopus 로고
    • The human immunoglobulin kappa locus consists of two copies that are organized in opposite polarity
    • Weichhold GM, Ohnheiser R, Zachau HG. The human immunoglobulin kappa locus consists of two copies that are organized in opposite polarity. Genomics. 1993;16:503-11.
    • (1993) Genomics , vol.16 , pp. 503-511
    • Weichhold, G.M.1    Ohnheiser, R.2    Zachau, H.G.3
  • 9
    • 0025923456 scopus 로고
    • The human immunoglobulin kappa locus. Characterization of the duplicated O regions
    • Pargent W, Meindl A, Thiebe R, Mitzel S, Zachau HG. The human immunoglobulin kappa locus. Characterization of the duplicated O regions. Eur J Immunol. 1991;21:1821-7.
    • (1991) Eur J Immunol , vol.21 , pp. 1821-1827
    • Pargent, W.1    Meindl, A.2    Thiebe, R.3    Mitzel, S.4    Zachau, H.G.5
  • 11
    • 0027420392 scopus 로고
    • The human immunoglobulin kappa locus. Characterization of the partially duplicated L regions
    • Huber C, Huber E, Lautner-Rieske A, Schable KF, Zachau HG. The human immunoglobulin kappa locus. Characterization of the partially duplicated L regions. Eur J Immunol. 1993;23:2860-7.
    • (1993) Eur J Immunol , vol.23 , pp. 2860-2867
    • Huber, C.1    Huber, E.2    Lautner-Rieske, A.3    Schable, K.F.4    Zachau, H.G.5
  • 12
    • 0021870867 scopus 로고
    • A uniform deleting element mediates the loss of kappa genes in human B cells
    • Siminovitch KA, Bakhshi A, Goldman P, Korsmeyer SJ. A uniform deleting element mediates the loss of kappa genes in human B cells. Nature. 1985;316:260-2.
    • (1985) Nature , vol.316 , pp. 260-262
    • Siminovitch, K.A.1    Bakhshi, A.2    Goldman, P.3    Korsmeyer, S.J.4
  • 13
    • 0028670764 scopus 로고
    • Detection of immunoglobulin κ light chain gene rearrangement patterns by Southern blot analysis
    • Beishuizen A, Verhoeven M-AJ, Mol EJ, Van Dongen JJM. Detection of immunoglobulin κ light chain gene rearrangement patterns by Southern blot analysis. Leukemia. 1994;8:2228-36.
    • (1994) Leukemia , vol.8 , pp. 2228-2236
    • Beishuizen, A.1    Verhoeven, M.-A.J.2    Mol, E.J.3    Van Dongen, J.J.M.4
  • 14
    • 0025729069 scopus 로고
    • Deletions of immunoglobulin C kappa region characterized by the circular excision products in mouse splenocytes
    • Shimizu T, Iwasato T, Yamagishi H. Deletions of immunoglobulin C kappa region characterized by the circular excision products in mouse splenocytes. J Exp Med. 1991;173:1065-72.
    • (1991) J Exp Med , vol.173 , pp. 1065-1072
    • Shimizu, T.1    Iwasato, T.2    Yamagishi, H.3
  • 15
    • 0027189754 scopus 로고
    • Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans
    • Takeda S, Zou YR, Bluethmann H, Kitamura D, Muller U, Rajewsky K. Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans. EMBO J. 1993;12:2329-36.
    • (1993) EMBO J , vol.12 , pp. 2329-2336
    • Takeda, S.1    Zou, Y.R.2    Bluethmann, H.3    Kitamura, D.4    Muller, U.5    Rajewsky, K.6
  • 16
    • 0024461826 scopus 로고
    • The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region
    • Meyer KB, Neuberger MS. The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region. EMBO J. 1989;8:1959-64.
    • (1989) EMBO J , vol.8 , pp. 1959-1964
    • Meyer, K.B.1    Neuberger, M.S.2
  • 17
    • 1542735785 scopus 로고
    • Two regulatory elements for immunoglobulin kappa light chain gene expression
    • U S A
    • Bergman Y, Rice D, Grosschedl R, Baltimore D. Two regulatory elements for immunoglobulin kappa light chain gene expression. Proc Natl Acad Sci U S A. 1984;81:7041-5.
    • (1984) Proc Natl Acad Sci , vol.81 , pp. 7041-7045
    • Bergman, Y.1    Rice, D.2    Grosschedl, R.3    Baltimore, D.4
  • 18
    • 0026774491 scopus 로고
    • Characterization of the human immunoglobulin kappa gene 3′ enhancer: Functional importance of three motifs that demonstrate B-cell-specific in vivo footprints
    • Judde JG, Max EE. Characterization of the human immunoglobulin kappa gene 3′ enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints. Mol Cell Biol. 1992;12:5206-16.
    • (1992) Mol Cell Biol , vol.12 , pp. 5206-5216
    • Judde, J.G.1    Max, E.E.2
  • 19
    • 0025025915 scopus 로고
    • Novel recombinations of the IG kappa-locus that result in allelic exclusion
    • Feddersen RM, Martin DJ, Van Ness BG. Novel recombinations of the IG kappa-locus that result in allelic exclusion. J Immunol. 1990;145:745-50.
    • (1990) J Immunol , vol.145 , pp. 745-750
    • Feddersen, R.M.1    Martin, D.J.2    Van Ness, B.G.3
  • 20
    • 0025096953 scopus 로고
    • The frequency of multiple recombination events occurring at the human Ig kappa L chain locus
    • Feddersen RM, Martin DJ, Van Ness BG. The frequency of multiple recombination events occurring at the human Ig kappa L chain locus. J Immunol. 1990;144:1088-93.
    • (1990) J Immunol , vol.144 , pp. 1088-1093
    • Feddersen, R.M.1    Martin, D.J.2    Van Ness, B.G.3
  • 21
    • 0034079057 scopus 로고    scopus 로고
    • Immunoglobulin kappa gene rearrangements between the kappa deleting element and Jkappa recombination signal sequences in acute lymphoblastic leukemia and normal hematopoiesis
    • Seriu T, Hansen-Hagge TE, Stark Y, Bartram CR. Immunoglobulin kappa gene rearrangements between the kappa deleting element and Jkappa recombination signal sequences in acute lymphoblastic leukemia and normal hematopoiesis. Leukemia. 2000;14:671-4.
    • (2000) Leukemia , vol.14 , pp. 671-674
    • Seriu, T.1    Hansen-Hagge, T.E.2    Stark, Y.3    Bartram, C.R.4
  • 23
    • 0023659483 scopus 로고
    • Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals
    • Hesse JE, Lieber MR, Gellert M, Mizuuchi K. Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals. Cell. 1987;49:775-83.
    • (1987) Cell , vol.49 , pp. 775-783
    • Hesse, J.E.1    Lieber, M.R.2    Gellert, M.3    Mizuuchi, K.4
  • 24
    • 0021240073 scopus 로고
    • Joining of V kappa to J kappa gene segments in a retroviral vector introduced into lymphoid cells
    • Lewis S, Gifford A, Baltimore D. Joining of V kappa to J kappa gene segments in a retroviral vector introduced into lymphoid cells. Nature. 1984;308:425-8.
    • (1984) Nature , vol.308 , pp. 425-428
    • Lewis, S.1    Gifford, A.2    Baltimore, D.3
  • 25
    • 0021885386 scopus 로고
    • DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes
    • Lewis S, Gifford A, Baltimore D. DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes. Science. 1985;228:677-85.
    • (1985) Science , vol.228 , pp. 677-685
    • Lewis, S.1    Gifford, A.2    Baltimore, D.3
  • 26
    • 33744469824 scopus 로고    scopus 로고
    • Immunoglobulin light chain gene rearrangments in precursor-B-ALL: Characteristics and applicability for the detection of minimal residual disease
    • Submitted
    • Van der Velden VHJ, De Bie M, van Wering ER, Van Dongen JJM. Immunoglobulin light chain gene rearrangments in precursor-B-ALL: characteristics and applicability for the detection of minimal residual disease. Haematologica. Submitted 2006.
    • (2006) Haematologica
    • Van Der Velden, V.H.J.1    De Bie, M.2    Van Wering, E.R.3    Van Dongen, J.J.M.4
  • 27
    • 17344367455 scopus 로고    scopus 로고
    • Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: Implications for selection of PCR targets for detection of minimal residual disease
    • Szczepanski T, Langerak AW, Wolvers-Tettero ILM, Ossenkoppele GJ, Verhoef G, Stul M, Petersen EJ, de Bruijn MAC, van't Veer MB, van Dongen JJM. Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: implications for selection of PCR targets for detection of minimal residual disease. Leukemia. 1998;12:1081-8.
    • (1998) Leukemia , vol.12 , pp. 1081-1088
    • Szczepanski, T.1    Langerak, A.W.2    Wolvers-Tettero, I.L.M.3    Ossenkoppele, G.J.4    Verhoef, G.5    Stul, M.6    Petersen, E.J.7    De Bruijn, M.A.C.8    Van't Veer, M.B.9    Van Dongen, J.J.M.10
  • 28
    • 0036114311 scopus 로고    scopus 로고
    • Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR
    • Van der Velden VH, Willemse MJ, van der Schoot CE, Hahlen K, van Wering ER, van Dongen JJ. Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR. Leukemia. 2002;16:928-36.
    • (2002) Leukemia , vol.16 , pp. 928-936
    • Van Der Velden, V.H.1    Willemse, M.J.2    Van Der Schoot, C.E.3    Hahlen, K.4    Van Wering, E.R.5    Van Dongen, J.J.6
  • 29
    • 0141725588 scopus 로고    scopus 로고
    • Age-related patterns of immunoglobulin and T-cell receptor gene rearrangements in precursor-B-ALL: Implications for detection of minimal residual disease
    • van der Velden VH, Szczepanski T, Wijkhuijs JM, Hart PG, Hoogeveen PG, Hop WC, van Wering ER, van Dongen JJ. Age-related patterns of immunoglobulin and T-cell receptor gene rearrangements in precursor-B-ALL: implications for detection of minimal residual disease. Leukemia. 2003;17:1834-44.
    • (2003) Leukemia , vol.17 , pp. 1834-1844
    • Van Der Velden, V.H.1    Szczepanski, T.2    Wijkhuijs, J.M.3    Hart, P.G.4    Hoogeveen, P.G.5    Hop, W.C.6    Van Wering, E.R.7    Van Dongen, J.J.8
  • 30
    • 0035865613 scopus 로고    scopus 로고
    • Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus
    • Van der Burg M, Tumkaya T, Boerma M, de Bruin-Versteeg S, Langerak AW, van Dongen JJ. Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus. Blood. 2001;97:1001-8.
    • (2001) Blood , vol.97 , pp. 1001-1008
    • Van Der Burg, M.1    Tumkaya, T.2    Boerma, M.3    De Bruin-Versteeg, S.4    Langerak, A.W.5    Van Dongen, J.J.6
  • 31
    • 0030442576 scopus 로고    scopus 로고
    • Ordering of human bone marrow B lymphocyte precursors by single-cell polymerase chain reaction analyses of the rearrangement status of the immunoglobulin H and L chain gene loci
    • Ghia P, ten Boekel E, Sanz E, de la Hera A, Rolink A, Melchers F. Ordering of human bone marrow B lymphocyte precursors by single-cell polymerase chain reaction analyses of the rearrangement status of the immunoglobulin H and L chain gene loci. J Exp Med. 1996;184:2217-29.
    • (1996) J Exp Med , vol.184 , pp. 2217-2229
    • Ghia, P.1    Ten Boekel, E.2    Sanz, E.3    De La Hera, A.4    Rolink, A.5    Melchers, F.6
  • 34
    • 0036054186 scopus 로고    scopus 로고
    • Immunoglobulin light chain gene rearrangements display hierarchy in absence of selection for functionality in precursor-B-ALL
    • van der Burg M, Barendregt BH, Szczepanski T, van Wering ER, Langerak AW, van Dongen JJ. Immunoglobulin light chain gene rearrangements display hierarchy in absence of selection for functionality in precursor-B-ALL. Leukemia. 2002;16:1448-53.
    • (2002) Leukemia , vol.16 , pp. 1448-1453
    • Van Der Burg, M.1    Barendregt, B.H.2    Szczepanski, T.3    Van Wering, E.R.4    Langerak, A.W.5    Van Dongen, J.J.6
  • 35
    • 10844274689 scopus 로고    scopus 로고
    • Tracing the pre-B to immature B cell transition in human leukemia cells reveals a coordinated sequence of primary and secondary IGK gene rearrangement, IGK deletion, and IGL gene rearrangement
    • Klein F, Feldhahn N, Mooster JL, Sprangers M, Hofmann WK, Wernet P, Wartenberg M, Muschen M. Tracing the pre-B to immature B cell transition in human leukemia cells reveals a coordinated sequence of primary and secondary IGK gene rearrangement, IGK deletion, and IGL gene rearrangement. J Immunol. 2005;174:367-75.
    • (2005) J Immunol , vol.174 , pp. 367-375
    • Klein, F.1    Feldhahn, N.2    Mooster, J.L.3    Sprangers, M.4    Hofmann, W.K.5    Wernet, P.6    Wartenberg, M.7    Muschen, M.8
  • 36
    • 0028305298 scopus 로고
    • Variable kappa gene rearrangement in lymphoproliferative disorders: An analysis of V kappa gene usage, VJ joining and somatic mutation
    • Cannell PK, Amlot P, Attard M, Hoffbrand AV, Foroni L. Variable kappa gene rearrangement in lymphoproliferative disorders: an analysis of V kappa gene usage, VJ joining and somatic mutation. Leukemia. 1994;8:1139-45.
    • (1994) Leukemia , vol.8 , pp. 1139-1145
    • Cannell, P.K.1    Amlot, P.2    Attard, M.3    Hoffbrand, A.V.4    Foroni, L.5
  • 37
    • 0027497795 scopus 로고
    • V kappa gene segments rearranged in chronic lymphocytic leukemia are distributed over a large portion of the V kappa locus and do not show somatic mutation
    • Wagner SD, Luzzatto L. V kappa gene segments rearranged in chronic lymphocytic leukemia are distributed over a large portion of the V kappa locus and do not show somatic mutation. Eur J Immunol. 1993;23:391-7.
    • (1993) Eur J Immunol , vol.23 , pp. 391-397
    • Wagner, S.D.1    Luzzatto, L.2
  • 38
    • 0028178499 scopus 로고
    • Similar patterns of V kappa gene usage but different degrees of somatic mutation in hairy cell leukemia, prolymphocytic leukemia, Waldenstrom's macroglobulinemia, and myeloma
    • Wagner SD, Martinelli V, Luzzatto L. Similar patterns of V kappa gene usage but different degrees of somatic mutation in hairy cell leukemia, prolymphocytic leukemia, Waldenstrom's macroglobulinemia, and myeloma. Blood. 1994;83:3647-53.
    • (1994) Blood , vol.83 , pp. 3647-3653
    • Wagner, S.D.1    Martinelli, V.2    Luzzatto, L.3
  • 39
    • 0022774288 scopus 로고
    • Light chains of immunoglobulins: Structural-genetic correlates
    • Solomon A. Light chains of immunoglobulins: structural-genetic correlates. Blood. 1986;68:603-10.
    • (1986) Blood , vol.68 , pp. 603-610
    • Solomon, A.1
  • 42
    • 0030614775 scopus 로고    scopus 로고
    • Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells
    • Sahota SS, Leo R, Hamblin TJ, Stevenson FK. Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells. Blood. 1997;89:219-26.
    • (1997) Blood , vol.89 , pp. 219-226
    • Sahota, S.S.1    Leo, R.2    Hamblin, T.J.3    Stevenson, F.K.4
  • 43
    • 0031959202 scopus 로고    scopus 로고
    • Characterization of the immunoglobulin light chain variable region gene expressed in multiple myeloma
    • Kiyoi H, Naito K, Ohno R, Saito H, Naoe T. Characterization of the immunoglobulin light chain variable region gene expressed in multiple myeloma. Leukemia. 1998;12:601-9.
    • (1998) Leukemia , vol.12 , pp. 601-609
    • Kiyoi, H.1    Naito, K.2    Ohno, R.3    Saito, H.4    Naoe, T.5
  • 44
    • 0031015724 scopus 로고    scopus 로고
    • Follicular lymphoma immunoglobulin kappa light chains are affected by the antigen selection process, but to a lesser degree than their partner heavy chains
    • Stamatopoulos K, Kosmas C, Papadaki T, Pouliou E, Belessi C, Afendaki S, Anagnostou D, Loukopoulos D. Follicular lymphoma immunoglobulin kappa light chains are affected by the antigen selection process, but to a lesser degree than their partner heavy chains. Br J Haematol. 1997;96:132-46.
    • (1997) Br J Haematol , vol.96 , pp. 132-146
    • Stamatopoulos, K.1    Kosmas, C.2    Papadaki, T.3    Pouliou, E.4    Belessi, C.5    Afendaki, S.6    Anagnostou, D.7    Loukopoulos, D.8
  • 48
  • 50
    • 0029894165 scopus 로고    scopus 로고
    • Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
    • Stanhope-Baker P, Hudson KM, Shaffer AL, Constantinescu A, Schlissel MS. Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell. 1996;85:887-97.
    • (1996) Cell , vol.85 , pp. 887-897
    • Stanhope-Baker, P.1    Hudson, K.M.2    Shaffer, A.L.3    Constantinescu, A.4    Schlissel, M.S.5
  • 51
    • 0032883119 scopus 로고    scopus 로고
    • Chromatin remodeling directly activates V(D)J recombination
    • U S A
    • Cherry SR, Baltimore D. Chromatin remodeling directly activates V(D)J recombination. Proc Natl Acad Sci U S A. 1999;96:10788-93.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 10788-10793
    • Cherry, S.R.1    Baltimore, D.2
  • 52
    • 0021983551 scopus 로고
    • Developmentally controlled and tissue-specific expression of unrearranged VH gene segments
    • Yancopoulos GD, Alt FW. Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell. 1985;40:271-81.
    • (1985) Cell , vol.40 , pp. 271-281
    • Yancopoulos, G.D.1    Alt, F.W.2
  • 53
    • 0345268756 scopus 로고    scopus 로고
    • Biallelic germline transcription at the kappa immunoglobulin locus
    • Singh N, Bergman Y, Cedar H, Chess A. Biallelic germline transcription at the kappa immunoglobulin locus. J Exp Med. 2003;197:743-50.
    • (2003) J Exp Med , vol.197 , pp. 743-750
    • Singh, N.1    Bergman, Y.2    Cedar, H.3    Chess, A.4
  • 54
    • 0029967078 scopus 로고    scopus 로고
    • Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement
    • Xu Y, Davidson L, Alt FW, Baltimore D. Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement. Immunity. 1996;4:377-85.
    • (1996) Immunity , vol.4 , pp. 377-385
    • Xu, Y.1    Davidson, L.2    Alt, F.W.3    Baltimore, D.4
  • 56
    • 0036097492 scopus 로고    scopus 로고
    • Essential roles of the kappa light chain intronic enhancer and 3′ enhancer in kappa rearrangement and demethylation
    • Inlay M, Alt FW, Baltimore D, Xu Y. Essential roles of the kappa light chain intronic enhancer and 3′ enhancer in kappa rearrangement and demethylation. Nat Immunol. 2002;3:463-8.
    • (2002) Nat Immunol , vol.3 , pp. 463-468
    • Inlay, M.1    Alt, F.W.2    Baltimore, D.3    Xu, Y.4
  • 58
    • 0024554495 scopus 로고
    • A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    • Murre C, McCaw PS, Baltimore D. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell. 1989;56:777-83.
    • (1989) Cell , vol.56 , pp. 777-783
    • Murre, C.1    McCaw, P.S.2    Baltimore, D.3
  • 60
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang Y, Soriano P, Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell. 1994;79:875-84.
    • (1994) Cell , vol.79 , pp. 875-884
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 62
    • 0035801454 scopus 로고    scopus 로고
    • Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells
    • Goebel P, Janney N, Valenzuela JR, Romanow WJ, Murre C, Feeney AJ. Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells. J Exp Med. 2001;194:645-56.
    • (2001) J Exp Med , vol.194 , pp. 645-656
    • Goebel, P.1    Janney, N.2    Valenzuela, J.R.3    Romanow, W.J.4    Murre, C.5    Feeney, A.J.6
  • 63
    • 2442587261 scopus 로고    scopus 로고
    • Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A
    • Quong MW, Martensson A, Langerak AW, Rivera RR, Nemazee D, Murre C. Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A. J Exp Med. 2004;199:1101-12.
    • (2004) J Exp Med , vol.199 , pp. 1101-1112
    • Quong, M.W.1    Martensson, A.2    Langerak, A.W.3    Rivera, R.R.4    Nemazee, D.5    Murre, C.6
  • 64
    • 0030038608 scopus 로고    scopus 로고
    • A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus
    • Kirillov A, Kistler B, Mostoslavsky R, Cedar H, Wirth T, Bergman Y. A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus. Nat Genet. 1996;13:435-41.
    • (1996) Nat Genet , vol.13 , pp. 435-441
    • Kirillov, A.1    Kistler, B.2    Mostoslavsky, R.3    Cedar, H.4    Wirth, T.5    Bergman, Y.6
  • 65
    • 12344270023 scopus 로고    scopus 로고
    • Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene
    • Roldan E, Fuxa M, Chong W, Martinez D, Novatchkova M, Busslinger M, Skok JA. Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. Nat Immunol. 2005;6:31-41.
    • (2005) Nat Immunol , vol.6 , pp. 31-41
    • Roldan, E.1    Fuxa, M.2    Chong, W.3    Martinez, D.4    Novatchkova, M.5    Busslinger, M.6    Skok, J.A.7
  • 66
    • 13244275244 scopus 로고    scopus 로고
    • Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells
    • Sayegh C, Jhunjhunwala S, Riblet R, Murre C. Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. Genes Dev. 2005;19:322-7.
    • (2005) Genes Dev , vol.19 , pp. 322-327
    • Sayegh, C.1    Jhunjhunwala, S.2    Riblet, R.3    Murre, C.4
  • 67
    • 0030792305 scopus 로고    scopus 로고
    • DNA methylation: Regulation of gene expression and role in the immune system
    • Mostoslavsky R, Bergman Y. DNA methylation: regulation of gene expression and role in the immune system. Biochim Biophys Acta. 1997;1333:F29-50.
    • (1997) Biochim Biophys Acta , vol.1333
    • Mostoslavsky, R.1    Bergman, Y.2
  • 68
    • 0036792721 scopus 로고    scopus 로고
    • Differential accessibility at the kappa chain locus plays a role in allelic exclusion
    • Goldmit M, Schlissel M, Cedar H, Bergman Y. Differential accessibility at the kappa chain locus plays a role in allelic exclusion. EMBO J. 2002;21:5255-61.
    • (2002) EMBO J , vol.21 , pp. 5255-5261
    • Goldmit, M.1    Schlissel, M.2    Cedar, H.3    Bergman, Y.4
  • 71
    • 0021270716 scopus 로고
    • Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation
    • Tsujimoto Y, Yunis J, Onorato-Showe L, Erikson J, Nowell PC, Croce CM. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science. 1984;224:1403-6.
    • (1984) Science , vol.224 , pp. 1403-1406
    • Tsujimoto, Y.1    Yunis, J.2    Onorato-Showe, L.3    Erikson, J.4    Nowell, P.C.5    Croce, C.M.6
  • 73
    • 0018749839 scopus 로고
    • Chromosome abnormalities in poorly differentiated lymphocytic lymphoma
    • Fukuhara S, Rowley JD, Variakojis D, Golomb HM. Chromosome abnormalities in poorly differentiated lymphocytic lymphoma. Cancer Res. 1979;39:3119-28.
    • (1979) Cancer Res , vol.39 , pp. 3119-3128
    • Fukuhara, S.1    Rowley, J.D.2    Variakojis, D.3    Golomb, H.M.4
  • 74
    • 0023275274 scopus 로고
    • Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas
    • Weiss LM, Warnke RA, Sklar J, Cleary ML. Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas. N Engl J Med. 1987;317:1185-9.
    • (1987) N Engl J Med , vol.317 , pp. 1185-1189
    • Weiss, L.M.1    Warnke, R.A.2    Sklar, J.3    Cleary, M.L.4
  • 75
    • 0345055662 scopus 로고
    • Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18
    • U S A
    • Cleary ML, Sklar J. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci U S A. 1985;82:7439-43.
    • (1985) Proc Natl Acad Sci , vol.82 , pp. 7439-7443
    • Cleary, M.L.1    Sklar, J.2
  • 76
    • 0024362848 scopus 로고
    • Detection of chromosomal translocation t(14;18) within the minor cluster region of bcl-2 by polymerase chain reaction and direct genomic sequencing of the enzymatically amplified DNA in follicular lymphomas
    • Ngan BY, Nourse J, Cleary ML. Detection of chromosomal translocation t(14;18) within the minor cluster region of bcl-2 by polymerase chain reaction and direct genomic sequencing of the enzymatically amplified DNA in follicular lymphomas. Blood. 1989;73:1759-62.
    • (1989) Blood , vol.73 , pp. 1759-1762
    • Ngan, B.Y.1    Nourse, J.2    Cleary, M.L.3
  • 77
    • 0021255587 scopus 로고
    • Malignant lymphomas with band 8q24 chromosome abnormality: A morphologic continuum extending from Burkitt's to immunoblastic lymphoma
    • Sigaux F, Berger R, Bernheim A, Valensi F, Daniel MT, Flandrin G. Malignant lymphomas with band 8q24 chromosome abnormality: a morphologic continuum extending from Burkitt's to immunoblastic lymphoma. Br J Haematol. 1984;57:393-405.
    • (1984) Br J Haematol , vol.57 , pp. 393-405
    • Sigaux, F.1    Berger, R.2    Bernheim, A.3    Valensi, F.4    Daniel, M.T.5    Flandrin, G.6
  • 78
    • 0017285882 scopus 로고
    • Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas
    • Zech L, Haglund U, Nilsson K, Klein G. Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas. Int J Cancer. 1976;17:47-56.
    • (1976) Int J Cancer , vol.17 , pp. 47-56
    • Zech, L.1    Haglund, U.2    Nilsson, K.3    Klein, G.4
  • 79
    • 0035839844 scopus 로고    scopus 로고
    • Translocations involving c-myc and c-myc function
    • Boxer LM, Dang CV. Translocations involving c-myc and c-myc function. Oncogene. 2001;20:5595-610.
    • (2001) Oncogene , vol.20 , pp. 5595-5610
    • Boxer, L.M.1    Dang, C.V.2
  • 82
    • 0000634556 scopus 로고
    • Variant translocation of the bcl-2 gene to immunoglobulin lambda light chain gene in chronic lymphocytic leukemia
    • U S A
    • Adachi M, Cossman J, Longo D, Croce CM, Tsujimoto Y. Variant translocation of the bcl-2 gene to immunoglobulin lambda light chain gene in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 1989;86:2771-4.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 2771-2774
    • Adachi, M.1    Cossman, J.2    Longo, D.3    Croce, C.M.4    Tsujimoto, Y.5
  • 83
    • 0024842136 scopus 로고
    • bcl-2 gene rearrangement analysis in Japanese B cell lymphoma; novel bcl-2 recombination with immunoglobulin kappa chain gene
    • Osada H, Seto M, Ueda R, Emi N, Takagi N, Obata Y, Suchi T, Takahashi T. bcl-2 gene rearrangement analysis in Japanese B cell lymphoma; novel bcl-2 recombination with immunoglobulin kappa chain gene. Jpn J Cancer Res. 1989;80:711-5.
    • (1989) Jpn J Cancer Res , vol.80 , pp. 711-715
    • Osada, H.1    Seto, M.2    Ueda, R.3    Emi, N.4    Takagi, N.5    Obata, Y.6    Suchi, T.7    Takahashi, T.8
  • 88
    • 0036796972 scopus 로고    scopus 로고
    • Detection of illegitimate rearrangements within the immunoglobulin light chain loci in B cell malignancies using end sequenced probes
    • Poulsen TS, Silahtaroglu AN, Gisselo CG, Tommerup N, Johnsen HE. Detection of illegitimate rearrangements within the immunoglobulin light chain loci in B cell malignancies using end sequenced probes. Leukemia. 2002;16:2148-55.
    • (2002) Leukemia , vol.16 , pp. 2148-2155
    • Poulsen, T.S.1    Silahtaroglu, A.N.2    Gisselo, C.G.3    Tommerup, N.4    Johnsen, H.E.5
  • 89
    • 0028860940 scopus 로고
    • The role of chromosome translocations in T cell acute leukemia
    • Hwang LY, Baer RJ. The role of chromosome translocations in T cell acute leukemia. Curr Opin Immunol. 1995;7:659-64.
    • (1995) Curr Opin Immunol , vol.7 , pp. 659-664
    • Hwang, L.Y.1    Baer, R.J.2
  • 91
    • 0038465916 scopus 로고    scopus 로고
    • Molecular immunoglobulin/T-cell receptor clonality analysis in cutaneous lymphoproliferations. Experience with the BIOMED-2 standardized polymerase chain reaction protocol
    • Sandberg Y, Heule F, Lam K, Lugtenburg PJ, Wolvers-Tettero IL, van Dongen JJ, Langerak AW. Molecular immunoglobulin/T-cell receptor clonality analysis in cutaneous lymphoproliferations. Experience with the BIOMED-2 standardized polymerase chain reaction protocol. Haematologica. 2003;88:659-70.
    • (2003) Haematologica , vol.88 , pp. 659-670
    • Sandberg, Y.1    Heule, F.2    Lam, K.3    Lugtenburg, P.J.4    Wolvers-Tettero, I.L.5    Van Dongen, J.J.6    Langerak, A.W.7
  • 92
    • 18744392540 scopus 로고    scopus 로고
    • B-cell clonality determination using an immunoglobulin kappa light chain polymerase chain reaction method
    • Pai RK, Chakerian AE, Binder JM, Amin M, Viswanatha DS. B-cell clonality determination using an immunoglobulin kappa light chain polymerase chain reaction method. J Mol Diagn. 2005;7:300-7.
    • (2005) J Mol Diagn , vol.7 , pp. 300-307
    • Pai, R.K.1    Chakerian, A.E.2    Binder, J.M.3    Amin, M.4    Viswanatha, D.S.5
  • 93
    • 26944441286 scopus 로고    scopus 로고
    • BIOMED-2 multiplex Ig/TCR PCR protocols can reliably replace Southern blot analysis in routine clonality diagnostics
    • Sandberg Y, van Gastel-Mol EJ, Verhaaf B, Lam KH, van Dongen JJM, Langerak AW. BIOMED-2 multiplex Ig/TCR PCR protocols can reliably replace Southern blot analysis in routine clonality diagnostics. J Mol Diagn. 2005;7:495-503.
    • (2005) J Mol Diagn , vol.7 , pp. 495-503
    • Sandberg, Y.1    Van Gastel-Mol, E.J.2    Verhaaf, B.3    Lam, K.H.4    Van Dongen, J.J.M.5    Langerak, A.W.6
  • 95
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999;94:1848-54.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 96
    • 0030639650 scopus 로고    scopus 로고
    • Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features
    • Johnson TA, Rassenti LZ, Kipps TJ. Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features. J Immunol. 1997;158:235-46.
    • (1997) J Immunol , vol.158 , pp. 235-246
    • Johnson, T.A.1    Rassenti, L.Z.2    Kipps, T.J.3
  • 97
    • 85117739237 scopus 로고    scopus 로고
    • Do B-cell chronic lymphocytic leukemia patients with Ig VH3-21 genes constitute a new subset of chronic lymphocytic leukemia?
    • author reply 1098-9
    • Nollet F, Cauwelier B, Billiet J, Selleslag D, Van Hoof A, Louwagie A, Criel A. Do B-cell chronic lymphocytic leukemia patients with Ig VH3-21 genes constitute a new subset of chronic lymphocytic leukemia? Blood. 2002;100:1097-8; author reply 1098-9.
    • (2002) Blood , vol.100 , pp. 1097-1098
    • Nollet, F.1    Cauwelier, B.2    Billiet, J.3    Selleslag, D.4    Van Hoof, A.5    Louwagie, A.6    Criel, A.7
  • 98
    • 0038281374 scopus 로고    scopus 로고
    • Features of the overexpressed V1-69 genes in the unmutated subset of chronic lymphocytic leukemia are distinct from those in the healthy elderly repertoire
    • Potter KN, Orchard J, Critchley E, Mockridge CI, Jose A, Stevenson FK. Features of the overexpressed V1-69 genes in the unmutated subset of chronic lymphocytic leukemia are distinct from those in the healthy elderly repertoire. Blood. 2003;101:3082-4.
    • (2003) Blood , vol.101 , pp. 3082-3084
    • Potter, K.N.1    Orchard, J.2    Critchley, E.3    Mockridge, C.I.4    Jose, A.5    Stevenson, F.K.6
  • 101
    • 0842344576 scopus 로고    scopus 로고
    • V(H)3-21 gene usage in chronic lymphocytic leukemia - Characterization of a new subgroup with distinct molecular features and poor survival
    • Tobin G, Soderberg O, Thunberg U, Rosenquist R. V(H)3-21 gene usage in chronic lymphocytic leukemia - characterization of a new subgroup with distinct molecular features and poor survival. Leuk Lymphoma. 2004;45:221-8.
    • (2004) Leuk Lymphoma , vol.45 , pp. 221-228
    • Tobin, G.1    Soderberg, O.2    Thunberg, U.3    Rosenquist, R.4
  • 104
    • 0028324602 scopus 로고
    • Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: Implications for the detection of minimal residual disease by polymerase chain reaction analysis
    • Beishuizen A, Verhoeven MA, van Wering ER, Hählen K, Hooijkaas H, van Dongen JJM. Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: implications for the detection of minimal residual disease by polymerase chain reaction analysis. Blood. 1994;83:2238-47.
    • (1994) Blood , vol.83 , pp. 2238-2247
    • Beishuizen, A.1    Verhoeven, M.A.2    Van Wering, E.R.3    Hählen, K.4    Hooijkaas, H.5    Van Dongen, J.J.M.6


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