Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: Implications for selection of PCR targets for detection of minimal residual disease

Leukemia

Volumn 12, Issue 7, 1998, Pages 1081-1088

  Szczepanski T ^a,b   Langerak, A W ^a   Wolvers Tettero, I L M ^a   Ossenkoppele, G J ^c   Verhoef, G ^d   Stul, M ^e   Petersen, E J ^f   De Bruijn, M A C ^a   Van't Veer, M B ^a   Van Dongen, J J M ^a,g  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b MEDICAL UNIVERSITY OF SILESIA   (Poland)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e UNIVERSITY OF LEUVEN   (Belgium)

^f UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^g ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Acute lymphoblastic leukemia; Adult ALL; Heteroduplex analysis; Ig and TCR gene rearrangements; Minimal residual disease (MRD); PCR; Southern blotting

Indexed keywords

HETERODUPLEX;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; DNA PROBE; FEMALE; GENE DELETION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; MALE; MINIMAL RESIDUAL DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING; T LYMPHOCYTE RECEPTOR GENE;

EID: 17344367455     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401071     Document Type: Article

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