B-cell clonality determination using an immunoglobulin κ light chain polymerase chain reaction method

Journal of Molecular Diagnostics

Volumn 7, Issue 2, 2005, Pages 300-307

  Pai, Reetesh K ^a   Chakerian, Artemis E ^a   Binder, John M ^c   Amin, Mitual ^c   Viswanatha, David S ^a,b  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b TRICORE REFERENCE LABORATORIES   (United States)

^c WILLIAM BEAUMONT HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; PARAFFIN;

ANALYTIC METHOD; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CAPILLARY ELECTROPHORESIS; CLONAL VARIATION; CONTROLLED STUDY; FOLLICULAR LYMPHOMA; GENE REARRANGEMENT; GENE SEQUENCE; GERMINAL CENTER; HODGKIN DISEASE; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOMA; LYMPHOID CELL; MAJOR CLINICAL STUDY; MANTLE CELL LYMPHOMA; MULTIGENE FAMILY; MULTIPLE MYELOMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PREDICTION; PSEUDOGENE; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; T CELL LYMPHOMA; T LYMPHOCYTE;

EID: 18744392540     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1525-1578(10)60558-2     Document Type: Article

References (28)

1. Inghirami G, Szalbolcs MJ, Yee HT, Corradini P, Cesarman E, Knowles DM: Detection of immunoglobulin gene rearrangement of B cell nonHodgkin's lymphomas and leukemias in fresh, unfixed and formalin-fixed, paraffin-embedded tissue by polymerase chain reaction. Lab Invest 1993, 68:746-757
2. Lehman CM, Sarago C, Nasim S, Comerford J, Karcher DS, Garrett CT: Comparison of Southern hybridization for the routine detection of immunoglobulin heavy chain gene rearrangements. Am J Clin Pathol 1995, 103:171-176
3. Diaz-Cano S: PCR-based alternative for diagnosis of immunoglobulin heavy chain gene rearrangement. Diag Mol Pathol 1996, 5:3-9
4. Medeiros LJ, Carr J: Overview of the role of molecular methods in the diagnosis of malignant lymphomas. Arch Pathol Lab Med 1999, 123:1189-1207
5. Diss TC, Pan L, Peng H, Wotherspoon AC, Isaacson PG: Sources of DNA for detecting B cell monoclonality using PCR. J Clin Pathol 1994, 47:493-496
6. Segal GH, Jorgensen T, Masih AS, Braylan RC: Optimal primer selection for clonality assessment by polymerase chain reaction analysis: I. Low grade B-cell lymphoproliferative disorders of nonfollicular center cell type. Hum Pathol 1994, 25:1268-1275
7. Achille A, Scarpa A, Montresor M, Scardoni M, Zamboni G, Chilosi M, Capelli P, Franzin G, Menstrina F: Routine application of polymerase chain reaction in the diagnosis of monoclonality of B-cell lymphoid proliferations. Diagn Mol Pathol 1995, 4:14-24
8. Deane M, McCarthy KP, Wiedemann LM, Norton JD: An improved method for detection of B-lymphoid clonality by polymerase chain reaction. Leukemia 1991, 5:726-730
9. Aubin J, Davi F, Nguyen-Salomon F, Leboeuf D, Debert C, Taher M, Valensi F, Canioni D, Brousse N, Varet B, Falndrin G, MacIntyre EA: Description of a novel FR1 IgH PCR strategy and its comparison with three other strategies for the detection of clonality in B cell malignancies. Leukemia 1995, 9:471-479
10. van der Burg M, Tumkaya T, Boerma M, de Bruin-Versteeg S, Langerak AW, van Dongen JJM: Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus. Blood 2001, 97:1001-1008
11. Simniovitch KA, Bakshi A, Goldman P, Korsmeyer SJ: A uniform deleting element mediates the loss of kappa genes in human B cells. Nature 1985, 316:260-262
12. Beishuizen A, Verhoeven MJ, Mol EJ, van Dongen JJM: Detection of immunoglobulin kappa light chain gene rearrangement patterns by Southern blot analysis. Leukemia 1994, 8:2228-2236
13. Jaffe ES, Harris NL, Stein H, Vardiman JW (Eds): World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Haematopoietic and Lymphoid Tissues. Lyon, IARC Press, 2001
14. van der Velden VHJ, Willemse MJ, van der Schoot CE, Hahlen K, van Wering ER, van Dongen JJM: Immunoglobulin kappa deleting element rearrangements in precursor-B acute B lymphoblastic leukemia are stable targets for detection of minimal residual disease. Leukemia 2002, 16:928-936
15. Gong JZ, Zheng S, Chiarle R, De Wolf-Peeters C, Palestro G, Frizzera G, Inghirami G: Detection of immunoglobulin κ light chain rearrangements by polymerase chain reaction. Am J Pathol 1999, 155:355-363
16. Diss TC, Liu HX, Du MQ, Isaacson PG: Improvements to B cell clonality analysis using PCR amplification of immunoglobulin light chain genes. J Clin Pathol Mol Pathol 2002, 55:98-101
17. Beaubier NT, Hart AP, Bartolo C, Willman CL, Viswanatha DS: Comparison of capillary electrophoresis and polyacrylamide gel electrophoresis for the evaluation of T and B cell clonality by polymerase chain reaction. Diagn Mol Pathol 2000, 9:121-131
18. Ranheim EA, Jones C, Zehnder JL: Sensitive detection of clonal immunoglobulin rearrangements in frozen and paraffin embedded tissues by polymerase chain reaction heteroduplex analysis. Diag Mol Path 2000, 9:177-183
19. Avery AK, Chakerian AE, Magotra A, Bononcini I, Viswanatha DS: Post-PCR chip-based capillary electrophoresis technique for B and T-cell clonality determination. Mod Pathol 2004, 17(Suppl 1):350A
20. van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hummel M, Lavender FL, Delabesse E, Davi F, Schuuring E, Garcia-Sanz R, van Krieken JH, Droese J, Gonzalez D, Bastard C, White HE, Spaargaren M, Gonzalez M, Parreira A, Smith JL, Morgan GJ, Kneba M, Macintyre EA: Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003, 17:2257-2317
21. Beishuizen A, de Bruijn MAC, Pongers-Willemse MJ, Verhoeven MAJ, van Wering ER, Hahlen K, Breit TM, de Bruin-Versteeg S, Hooijkaas H, van Dongen JJM: Heterogeneity in junctional regions of immunoglobulin kappa deleting element rearrangements in B cell leukemias: a new molecular target for detection of minimal residual disease. Leukemia 1997, 11:2200-2207
22. Brauninger A, Goossens T, Rajewsky K, Kuppers R: Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human. Eur J Immunol 2001, 31:3631-3637
23. Cannell PK, Amlot P, Attard M, Hoffbrand AV, Foroni L: Variable kappa gene rearrangement in lymphoproliferative disorders: an analysis of Vk gene usage, VJ joining and somatic mutation. Leukemia 1994, 8:1139-1145
24. Meindl A, Klobeck J, Ohnheiser R, Zachau HG: The Vk gene repertoire in the human germ line. Eur J Immunol 1990, 20:1855-1863
25. Solomon A: Light chains of immunoglobulins: structural-genetic correlates. Blood 1986, 68;603-610
26. Cox JPL, Tomlinson IM, Winter G: A directory of human germ-line Vk segments reveals a strong bias in their usage. Eur J Immunol 1994, 24:827-836
27. Foster SJ, Brezinschek H, Brezinschek RI, Lipsky PE: Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells. J Clin Invest 1997, 99:1614-1627
28. Feddersen RM, Martin DJ, Van Ness BG: The frequency of multiple recombination events occurring at the human Igk L chain locus. J Immunol 1990, 144:1088-1093