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Volumn 89, Issue 1, 1997, Pages 219-226

Myeloma V(L) and V(H) gene sequences reveal a complementary imprint of antigen selection in tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; GENE CLUSTER; GENE MUTATION; GENE SEQUENCE; HUMAN; MOLECULAR CLONING; MYELOMA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; AMINO ACID SEQUENCE; BONE MARROW; CANCER STEM CELL; CHEMISTRY; COMPARATIVE STUDY; GENE REARRANGEMENT; GENETICS; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR GENETICS; MULTIPLE MYELOMA; PATHOLOGY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

EID: 0030614775     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.1.219.219_219_226     Document Type: Article
Times cited : (85)

References (40)
  • 1
    • 0018721299 scopus 로고
    • Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point in B-cell differentiation
    • Kubagawa, H, Vogler LB, Capra JD, Conrad ME, Lawton AR, Cooper MD: Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point in B-cell differentiation. J Exp Med 150:792, 1979
    • (1979) J Exp Med , vol.150 , pp. 792
    • Kubagawa, H.1    Vogler, L.B.2    Capra, J.D.3    Conrad, M.E.4    Lawton, A.R.5    Cooper, M.D.6
  • 3
    • 0026786675 scopus 로고
    • Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation
    • Bakkus MHC, Heirman C, van Riet I, van Camp B, Thielemans K: Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation. Blood 80:2326, 1992
    • (1992) Blood , vol.80 , pp. 2326
    • Bakkus, M.H.C.1    Heirman, C.2    Van Riet, I.3    Van Camp, B.4    Thielemans, K.5
  • 4
    • 0027991864 scopus 로고
    • Assessment of the role of clonogenic B lymphocytes in the pathogenesis of multiple myeloma
    • Sahota S, Hamblin T, Oscier DG, Stevenson FK: Assessment of the role of clonogenic B lymphocytes in the pathogenesis of multiple myeloma. Leukemia 8:1285, 1994
    • (1994) Leukemia , vol.8 , pp. 1285
    • Sahota, S.1    Hamblin, T.2    Oscier, D.G.3    Stevenson, F.K.4
  • 9
    • 0026636759 scopus 로고
    • Clonal evolution of a follicular lymphoma: Evidence for antigen selection
    • Bahler DW, Levy R: Clonal evolution of a follicular lymphoma: Evidence for antigen selection. Proc Natl Acad Sci USA 89:6770, 1992
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6770
    • Bahler, D.W.1    Levy, R.2
  • 10
    • 0028341604 scopus 로고
    • Clonal history of a human follicular lymphoma as revealed in the immunoglobulin variable region genes
    • Zhu D, Hawkins RE, Hamblin TJ, Stevenson FK: Clonal history of a human follicular lymphoma as revealed in the immunoglobulin variable region genes. Br J Haematol 86:505, 1994
    • (1994) Br J Haematol , vol.86 , pp. 505
    • Zhu, D.1    Hawkins, R.E.2    Hamblin, T.J.3    Stevenson, F.K.4
  • 11
    • 0026844401 scopus 로고
    • The development of B cells and the B cell repertoire in the microenvironment of the germinal centre
    • Berek C: The development of B cells and the B cell repertoire in the microenvironment of the germinal centre. Immunol Rev 126:5, 1992
    • (1992) Immunol Rev , vol.126 , pp. 5
    • Berek, C.1
  • 12
    • 0027296754 scopus 로고
    • Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to a Cμ sequence in IgG and IgA secreting multiple myelomas
    • Corradini P, Boccadoro M, Voena C, Pileri A: Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to a Cμ sequence in IgG and IgA secreting multiple myelomas. J Exp Med 178:1091, 1993
    • (1993) J Exp Med , vol.178 , pp. 1091
    • Corradini, P.1    Boccadoro, M.2    Voena, C.3    Pileri, A.4
  • 13
    • 0027257608 scopus 로고
    • The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell
    • Billadeau D, Ahmann G, Greipp P, van Ness B: The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell. J Exp Med 178:1023, 1993
    • (1993) J Exp Med , vol.178 , pp. 1023
    • Billadeau, D.1    Ahmann, G.2    Greipp, P.3    Van Ness, B.4
  • 15
    • 0028686184 scopus 로고
    • Antibody structure and the evolution of immunoglobulin V gene segments
    • Kirkham PM, Schroeder HW Jr: Antibody structure and the evolution of immunoglobulin V gene segments. Semin Immunol 6:347, 1994
    • (1994) Semin Immunol , vol.6 , pp. 347
    • Kirkham, P.M.1    Schroeder Jr., H.W.2
  • 16
    • 0024327901 scopus 로고
    • Stable expression and somatic hypermutation of antibody V regions in B cell development pathways
    • Kocks C, Rajewsky K: Stable expression and somatic hypermutation of antibody V regions in B cell development pathways. Annu Rev Immunol 7:537, 1989
    • (1989) Annu Rev Immunol , vol.7 , pp. 537
    • Kocks, C.1    Rajewsky, K.2
  • 17
    • 0027932998 scopus 로고
    • H genes are inherently susceptible to amino acid replacement
    • H genes are inherently susceptible to amino acid replacement. Immunol Today 15:367, 1994
    • (1994) Immunol Today , vol.15 , pp. 367
    • Chang, B.1    Casali, P.2
  • 19
    • 0026519543 scopus 로고
    • Multiparameter analyses of normal and malignant human plasma cells: CD38 ++, CD56+, CD54+, Clg is the common phenotype of myeloma cells
    • Leo R, Boeker M, Peest D, Hein R, Bartl R, Gessner JE, Selbach G, Wacker G, Deicher H: Multiparameter analyses of normal and malignant human plasma cells: CD38 ++, CD56+, CD54+, Clg is the common phenotype of myeloma cells. Ann Hematol 64:132, 1992
    • (1992) Ann Hematol , vol.64 , pp. 132
    • Leo, R.1    Boeker, M.2    Peest, D.3    Hein, R.4    Bartl, R.5    Gessner, J.E.6    Selbach, G.7    Wacker, G.8    Deicher, H.9
  • 20
    • 0028364706 scopus 로고
    • Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines
    • Hawkins RE, Zhu D, Ovecka M, Winter G, Hamblin TJ, Long A, Stevenson FK: Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines. Blood 83:3279, 1994
    • (1994) Blood , vol.83 , pp. 3279
    • Hawkins, R.E.1    Zhu, D.2    Ovecka, M.3    Winter, G.4    Hamblin, T.J.5    Long, A.6    Stevenson, F.K.7
  • 22
    • 0022774288 scopus 로고
    • Light chains of immunoglobulins: Structural-genetic correlates
    • Solomon A: Light chains of immunoglobulins: Structural-genetic correlates. Blood 68:603, 1986
    • (1986) Blood , vol.68 , pp. 603
    • Solomon, A.1
  • 24
    • 0028305298 scopus 로고
    • Variable κ gene rearrangement in lymphoproliferative disorders and analysis of Vκ gene usage, VJ joining and somatic mutation
    • Cannell PK, Amlot P, Attard M, Hoffbrand AV, Foroni L: Variable κ gene rearrangement in lymphoproliferative disorders and analysis of Vκ gene usage, VJ joining and somatic mutation. Leukemia 8:1139, 1994
    • (1994) Leukemia , vol.8 , pp. 1139
    • Cannell, P.K.1    Amlot, P.2    Attard, M.3    Hoffbrand, A.V.4    Foroni, L.5
  • 25
    • 0023267620 scopus 로고
    • High frequency expression of a conserved κ light-chain variable-region gene in chronic lymphocytic leukemia
    • Kipps TJ, Fong S, Tomhave E, Chen PP, Goldfein R, Carson D: High frequency expression of a conserved κ light-chain variable-region gene in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 84:2916, 1987
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2916
    • Kipps, T.J.1    Fong, S.2    Tomhave, E.3    Chen, P.P.4    Goldfein, R.5    Carson, D.6
  • 26
    • 0002960871 scopus 로고
    • The human immunoglobulin κ genes
    • Honjo T, Alt FW (eds): San Diego, CA, Academic
    • Zachau HG: The human immunoglobulin κ genes, in Honjo T, Alt FW (eds): Immunoglobulin Genes. San Diego, CA, Academic, 1995, p 173
    • (1995) Immunoglobulin Genes , pp. 173
    • Zachau, H.G.1
  • 27
    • 0027201551 scopus 로고
    • Cloning and sequencing of human immunoglobulin V gene segments
    • Williams SC, Winter G: Cloning and sequencing of human immunoglobulin V gene segments. Eur J Immunol 23:1456, 1993
    • (1993) Eur J Immunol , vol.23 , pp. 1456
    • Williams, S.C.1    Winter, G.2
  • 28
    • 0027428398 scopus 로고
    • Expressed human immunoglobulin κ genes and their hypermutation
    • Klein R, Jaenichen R, Zachau HG: Expressed human immunoglobulin κ genes and their hypermutation. Eur J Immunol 23:3248, 1993
    • (1993) Eur J Immunol , vol.23 , pp. 3248
    • Klein, R.1    Jaenichen, R.2    Zachau, H.G.3
  • 29
    • 0029664365 scopus 로고    scopus 로고
    • H gene mutational patterns indicate different tumor cell status in human myeloma and MGUS
    • H gene mutational patterns indicate different tumor cell status in human myeloma and MGUS. Blood 87:746, 1996
    • (1996) Blood , vol.87 , pp. 746
    • Sahota, S.S.1    Leo, R.2    Hamblin, T.J.3    Stevenson, F.K.4
  • 32
    • 0027476846 scopus 로고
    • Immunological memory
    • Gray D: Immunological memory. Annu Rev Immunol 11:49, 1993
    • (1993) Annu Rev Immunol , vol.11 , pp. 49
    • Gray, D.1
  • 33
  • 34
    • 0027232455 scopus 로고
    • Advancement of multiple myeloma from diagnosis through plateau phase to progression does not involve a new B-cell clone: Evidence from the Ig heavy chain gene
    • Ralph QM, Brisco MJ, Joshua DE, Brown R, Gibson J, Morley AA: Advancement of multiple myeloma from diagnosis through plateau phase to progression does not involve a new B-cell clone: Evidence from the Ig heavy chain gene. Blood 82:202, 1993
    • (1993) Blood , vol.82 , pp. 202
    • Ralph, Q.M.1    Brisco, M.J.2    Joshua, D.E.3    Brown, R.4    Gibson, J.5    Morley, A.A.6
  • 35
    • 0027753921 scopus 로고
    • The immunoglobulin κ locus-or-what has been learned from looking closely at one-tenth of a percent of the human genome
    • Zachau HG: The immunoglobulin κ locus-or-what has been learned from looking closely at one-tenth of a percent of the human genome. Gene 135:167, 1993
    • (1993) Gene , vol.135 , pp. 167
    • Zachau, H.G.1
  • 36
    • 0028326520 scopus 로고
    • A directory of human germ-line Vκ segments reveals a strong bias in their usage
    • Cox JPL, Tomlinson IM, Winter G: A directory of human germ-line Vκ segments reveals a strong bias in their usage. Eur J Immunol 24:827, 1994
    • (1994) Eur J Immunol , vol.24 , pp. 827
    • Cox, J.P.L.1    Tomlinson, I.M.2    Winter, G.3
  • 37
    • 0028178499 scopus 로고
    • Similar patterns of Vκ gene usage but different degrees of somatic mutation in hairy cell leukemia, prolymphocytic leukemia, Waldenstrom's macroglobulineumia, and myeloma
    • Wagner SD, Martinelli V, Luzzatto L: Similar patterns of Vκ gene usage but different degrees of somatic mutation in hairy cell leukemia, prolymphocytic leukemia, Waldenstrom's macroglobulineumia, and myeloma. Blood 83:3647, 1994
    • (1994) Blood , vol.83 , pp. 3647
    • Wagner, S.D.1    Martinelli, V.2    Luzzatto, L.3
  • 38
    • 0028246112 scopus 로고
    • Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell
    • Bakkus MHC, van Riet I, van Camp B, Thielemans K: Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell. Br J Haematol 87:68, 1994
    • (1994) Br J Haematol , vol.87 , pp. 68
    • Bakkus, M.H.C.1    Van Riet, I.2    Van Camp, B.3    Thielemans, K.4
  • 40
    • 85011831451 scopus 로고
    • From the structure of antibodies to the diversification of the immune response. Nobel Lecture
    • Milstein C: From the structure of antibodies to the diversification of the immune response. Nobel Lecture. Scand J Immunol 37:385, 1993
    • (1993) Scand J Immunol , vol.37 , pp. 385
    • Milstein, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.