Somatically mutated Ig VH3-21 genes characterize a new subset of chronic lymphocytic leukemia

Blood

Volumn 99, Issue 6, 2002, Pages 2262-2264

  Tobin, Gerard ^a,b   Thunberg, Ulf ^a,b   Johnson, Anna ^a,b   Thörn, Ingrid ^a,b   Söderberg, Ola ^a,b   Hultdin, Magnus ^a,b   Botling, Johan ^a,b   Enblad, Gunilla ^a,b   Sällström, Jan ^a,b   Sundström, Christer ^a,b   Roos, Göran ^a,b   Rosenquist, Richard ^a,b,c  

^a UPPSALA UNIVERSITY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; B CELL LEUKEMIA; CANCER SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL FEATURE; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE MUTATION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; PRIORITY JOURNAL; SOMATIC MUTATION;

EID: 0037085801     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.6.2262     Document Type: Article

References (19)

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4. Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features
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6. Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors
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19. VH3-21 B cells escape from a state of tolerance in rheumatoid arthritis and secrete rheumatoid factor