Evolutionary dynamics of the human immunoglobulin κ locus and the germline repertoire of the Vκ genes

European Journal of Immunology

Volumn 31, Issue 4, 2001, Pages 1017-1028

  Kawasaki, Kazuhiko ^a,b   Minoshima, Shinsei ^a   Nakato, Eriko ^a   Shibuya, Kazunori ^a   Shintani, Ai ^a,b   Asakawa, Shuichi ^a,b   Sasaki, Takashi ^a,b   Klobeck, H Gustav ^c   Combriato, Gabriele ^c   Zachau, Hans G ^c   Shimizu, Nobuyoshi ^a,b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Evolution; Genome sequence; Germline repertoire; Immunoglobulin locus; Inverted duplication

Indexed keywords

IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; NUCLEOTIDE;

ARTICLE; CHROMOSOME 22; CHROMOSOME INVERSION; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; DATA BASE; DNA TRANSPOSITION; DYNAMICS; EVOLUTION; GENE DUPLICATION; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HYBRIDIZATION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; MEDICAL LITERATURE; MULTIGENE FAMILY; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POINT MUTATION; PRIORITY JOURNAL; PSEUDOGENE; SEQUENCE HOMOLOGY;

BASE COMPOSITION; CHROMOSOMES, HUMAN, PAIR 22; DATABASES; EVOLUTION, MOLECULAR; GENE DUPLICATION; GENES, DUPLICATE; GENES, IMMUNOGLOBULIN; GERM-LINE MUTATION; HUMANS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; MUTAGENESIS; OPEN READING FRAMES; PHYLOGENY; PHYSICAL CHROMOSOME MAPPING; PSEUDOGENES; REPETITIVE SEQUENCES, NUCLEIC ACID; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; TERMINOLOGY;

EID: 0035061129     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200104)31:4<1017::AID-IMMU1017>3.0.CO;2-3     Document Type: Article

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