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Volumn 11, Issue 13-14, 2006, Pages 646-654

Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases

Author keywords

[No Author keywords available]

Indexed keywords

2 ISOPROPYLIDENEHYDRAZONO 4 OXO 5 THIAZOLIDINYLACETANILIDE; 4 OXO N PHENYL 4,5 DIHYDRO 2 [(1 METHYLETHYLIDENE)HYDRAZINO] 5 THIAZOLEACETAMIDE; ACETAMIDE DERIVATIVE; ACETYLSALICYLIC ACID; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT BREAKER; ADVANCED GLYCATION END PRODUCT INHIBITOR; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALAGEBRIUM; ALT 946; AMINOGUANIDINE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIOXIDANT; BLOCKING AGENT; BROMINE DERIVATIVE; CAN C; CARNOSINE; CLIOQUINOL; DEFEROXAMINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HOMOCARNOSINE; IRON CHELATING AGENT; METFORMIN; N [[2 (HYDRAZINOIMINOMETHYL)AMINO]ETHYL]ACETAMIDE; N ACETYLCARNOSINE; N PHENACYL 1,3 THIAZOLIUM BROMIDE; NIFEDIPINE; PERINDOPRIL; PRODRUG; PYRIDORIN; PYRIDOXAMINE; SOLUBLE ADVANCED GLYCATION END PRODUCT RECEPTOR; TENILSETAM; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 33745190013     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2006.05.016     Document Type: Review
Times cited : (237)

References (110)
  • 1
    • 0000916315 scopus 로고
    • Action of amino acids on sugars. Formation of melanoidins in a methodical way
    • Maillard L.C. Action of amino acids on sugars. Formation of melanoidins in a methodical way. Compt. Rend. 154 (1912) 66-68
    • (1912) Compt. Rend. , vol.154 , pp. 66-68
    • Maillard, L.C.1
  • 2
    • 21444449221 scopus 로고    scopus 로고
    • The role of AGEs and AGE inhibitors in diabetic cardiovascular disease
    • Thomas M.C., et al. The role of AGEs and AGE inhibitors in diabetic cardiovascular disease. Curr. Drug Targets 6 (2005) 453-474
    • (2005) Curr. Drug Targets , vol.6 , pp. 453-474
    • Thomas, M.C.1
  • 3
    • 11144324314 scopus 로고    scopus 로고
    • Advanced glycation endproducts-role in pathology of diabetic complications
    • Ahmed N. Advanced glycation endproducts-role in pathology of diabetic complications. Diabetes Res. Clin. Pract. 67 (2005) 3-21
    • (2005) Diabetes Res. Clin. Pract. , vol.67 , pp. 3-21
    • Ahmed, N.1
  • 4
    • 0036080646 scopus 로고    scopus 로고
    • Involvement of Maillard reactions in Alzheimer disease
    • Reddy V.P., et al. Involvement of Maillard reactions in Alzheimer disease. Neurotox. Res. 4 (2002) 191-209
    • (2002) Neurotox. Res. , vol.4 , pp. 191-209
    • Reddy, V.P.1
  • 5
    • 9644308246 scopus 로고    scopus 로고
    • Advanced glycation and endothelial functions: A link towards vascular complications in diabetes
    • Rojas A., and Morales M.A. Advanced glycation and endothelial functions: A link towards vascular complications in diabetes. Life Sci. 76 (2004) 715-730
    • (2004) Life Sci. , vol.76 , pp. 715-730
    • Rojas, A.1    Morales, M.A.2
  • 6
    • 0037347268 scopus 로고    scopus 로고
    • Glycation-a sweet tempter for neuronal death
    • Kikuchi S., et al. Glycation-a sweet tempter for neuronal death. Brain Res. Brain Res. Rev. 41 (2003) 306-323
    • (2003) Brain Res. Brain Res. Rev. , vol.41 , pp. 306-323
    • Kikuchi, S.1
  • 7
    • 0142026785 scopus 로고    scopus 로고
    • Intervention against the Maillard reaction in vivo
    • Monnier V.M. Intervention against the Maillard reaction in vivo. Arch. Biochem. Biophys. 419 (2003) 1-15
    • (2003) Arch. Biochem. Biophys. , vol.419 , pp. 1-15
    • Monnier, V.M.1
  • 8
    • 0035028667 scopus 로고    scopus 로고
    • Protein glycation: creation of catalytic sites for free radical generation
    • Yim M.B., et al. Protein glycation: creation of catalytic sites for free radical generation. Ann. N. Y. Acad. Sci. 928 (2001) 48-53
    • (2001) Ann. N. Y. Acad. Sci. , vol.928 , pp. 48-53
    • Yim, M.B.1
  • 9
    • 13144252260 scopus 로고    scopus 로고
    • Tobacco smoke is a source of toxic reactive glycation products
    • Cerami C., et al. Tobacco smoke is a source of toxic reactive glycation products. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 13915-13920
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 13915-13920
    • Cerami, C.1
  • 10
    • 0006217121 scopus 로고    scopus 로고
    • Advanced glycation end products and cigarette smoking
    • Nicholl I.D., and Bucala R. Advanced glycation end products and cigarette smoking. Cell. Mol. Biol. 44 (1998) 1025-1033
    • (1998) Cell. Mol. Biol. , vol.44 , pp. 1025-1033
    • Nicholl, I.D.1    Bucala, R.2
  • 11
    • 23744474803 scopus 로고    scopus 로고
    • Advanced glycation in health and disease: Role of the modern environment
    • Vlassara H. Advanced glycation in health and disease: Role of the modern environment. Ann. N. Y. Acad. Sci. 1043 (2005) 452-460
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 452-460
    • Vlassara, H.1
  • 12
    • 0037069350 scopus 로고    scopus 로고
    • A previously undescribed chemical link between smoking and metabolic disease
    • Dickerson T.J., and Janda K.D. A previously undescribed chemical link between smoking and metabolic disease. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 15084-15088
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 15084-15088
    • Dickerson, T.J.1    Janda, K.D.2
  • 13
    • 23044491409 scopus 로고    scopus 로고
    • Receptor for advanced glycation end product (RAGE) upregulation in human gingival fibroblasts incubated with nornicotine
    • Katz J., et al. Receptor for advanced glycation end product (RAGE) upregulation in human gingival fibroblasts incubated with nornicotine. J. Periodontol. 76 (2005) 1171-1174
    • (2005) J. Periodontol. , vol.76 , pp. 1171-1174
    • Katz, J.1
  • 14
    • 28844485738 scopus 로고    scopus 로고
    • The advanced glycation end product pentosidine correlates to IL-6 and other relevant inflammatory markers in rheumatoid arthritis
    • Hein G.E., et al. The advanced glycation end product pentosidine correlates to IL-6 and other relevant inflammatory markers in rheumatoid arthritis. Rheumatol. Int. 26 (2005) 137-141
    • (2005) Rheumatol. Int. , vol.26 , pp. 137-141
    • Hein, G.E.1
  • 15
    • 0032489290 scopus 로고    scopus 로고
    • Increased pentosidine, an advanced glycation end product, in plasma and synovial fluid from patients with rheumatoid arthritis and its relation with inflammatory markers
    • Miyata T., et al. Increased pentosidine, an advanced glycation end product, in plasma and synovial fluid from patients with rheumatoid arthritis and its relation with inflammatory markers. Biochem. Biophys. Res. Commun. 244 (1998) 45-49
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 45-49
    • Miyata, T.1
  • 16
    • 11944272384 scopus 로고
    • Glycation products and the pathogenesis of diabetic complications
    • Brownlee M. Glycation products and the pathogenesis of diabetic complications. Diabetes Care 15 (1992) 1835-1843
    • (1992) Diabetes Care , vol.15 , pp. 1835-1843
    • Brownlee, M.1
  • 17
    • 11844286912 scopus 로고    scopus 로고
    • Advanced glycation end product (AGE) inhibitors and their therapeutic implications in diseases
    • Takeuchi M., et al. Advanced glycation end product (AGE) inhibitors and their therapeutic implications in diseases. Int. J. Clin. Pharmacol. Res. 24 (2004) 95-101
    • (2004) Int. J. Clin. Pharmacol. Res. , vol.24 , pp. 95-101
    • Takeuchi, M.1
  • 18
    • 0025945553 scopus 로고
    • Formation of pentosidine during nonenzymic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo
    • Dyer D.G., et al. Formation of pentosidine during nonenzymic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo. J. Biol. Chem. 266 (1991) 11654-11660
    • (1991) J. Biol. Chem. , vol.266 , pp. 11654-11660
    • Dyer, D.G.1
  • 19
    • 0035830924 scopus 로고    scopus 로고
    • Early glycation products produce pentosidine cross-links on native proteins: novel mechanism of pentosidine formation and propagation of glycation
    • Chellan P., and Nagaraj R.H. Early glycation products produce pentosidine cross-links on native proteins: novel mechanism of pentosidine formation and propagation of glycation. J. Biol. Chem. 276 (2001) 3895-3903
    • (2001) J. Biol. Chem. , vol.276 , pp. 3895-3903
    • Chellan, P.1    Nagaraj, R.H.2
  • 20
    • 0035869429 scopus 로고    scopus 로고
    • Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: Comparison with pentosidine
    • Wilker S.C., et al. Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: Comparison with pentosidine. Anal. Biochem. 290 (2001) 353-358
    • (2001) Anal. Biochem. , vol.290 , pp. 353-358
    • Wilker, S.C.1
  • 21
    • 13844266010 scopus 로고    scopus 로고
    • High serum pentosidine concentrations are associated with increased arterial stiffness and thickness in patients with type 2 diabetes
    • Yoshida N., et al. High serum pentosidine concentrations are associated with increased arterial stiffness and thickness in patients with type 2 diabetes. Metabolism 54 (2005) 345-350
    • (2005) Metabolism , vol.54 , pp. 345-350
    • Yoshida, N.1
  • 22
    • 0029998967 scopus 로고    scopus 로고
    • The presence of a glucose-derived Maillard reaction product in the human lens
    • Nagaraj R.H., and Sady C. The presence of a glucose-derived Maillard reaction product in the human lens. FEBS Lett. 382 (1996) 234-238
    • (1996) FEBS Lett. , vol.382 , pp. 234-238
    • Nagaraj, R.H.1    Sady, C.2
  • 23
    • 0030924025 scopus 로고    scopus 로고
    • Advanced glycation modification of Rosenthal fibers in patients with Alexander disease
    • Castellani R.J., et al. Advanced glycation modification of Rosenthal fibers in patients with Alexander disease. Neurosci. Lett. 231 (1997) 79-82
    • (1997) Neurosci. Lett. , vol.231 , pp. 79-82
    • Castellani, R.J.1
  • 24
    • 0033179670 scopus 로고    scopus 로고
    • Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes
    • Chellan P., and Nagaraj R.H. Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes. Arch. Biochem. Biophys. 368 (1999) 98-104
    • (1999) Arch. Biochem. Biophys. , vol.368 , pp. 98-104
    • Chellan, P.1    Nagaraj, R.H.2
  • 25
    • 0038779570 scopus 로고    scopus 로고
    • Increased levels of advanced glycation end products in human cataractous lenses
    • Franke S., et al. Increased levels of advanced glycation end products in human cataractous lenses. J. Cataract Refract. Surg. 29 (2003) 998-1004
    • (2003) J. Cataract Refract. Surg. , vol.29 , pp. 998-1004
    • Franke, S.1
  • 26
    • 0035879693 scopus 로고    scopus 로고
    • ε-(Carboxymethyl) lysine and hexitol-lysine
    • ε-(Carboxymethyl) lysine and hexitol-lysine. Free Radic. Biol. Med. 31 (2001) 175-180
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 175-180
    • Castellani, R.J.1
  • 27
    • 23744447530 scopus 로고    scopus 로고
    • Dicarbonyl intermediates in the Maillard reaction
    • Thornalley P.J. Dicarbonyl intermediates in the Maillard reaction. Ann. N. Y. Acad. Sci. 1043 (2005) 111-117
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 111-117
    • Thornalley, P.J.1
  • 28
    • 0037067723 scopus 로고    scopus 로고
    • Identification and quantification of major Maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound
    • Biemel K.M., et al. Identification and quantification of major Maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound. J. Biol. Chem. 277 (2002) 24907-24915
    • (2002) J. Biol. Chem. , vol.277 , pp. 24907-24915
    • Biemel, K.M.1
  • 29
    • 0035968307 scopus 로고    scopus 로고
    • Formation pathways for lysine-arginine cross-links derived from hexoses and pentoses by Maillard processes. Unraveling the structure of a pentosidine precursor
    • Biemel K.M., et al. Formation pathways for lysine-arginine cross-links derived from hexoses and pentoses by Maillard processes. Unraveling the structure of a pentosidine precursor. J. Biol. Chem. 276 (2001) 23405-23412
    • (2001) J. Biol. Chem. , vol.276 , pp. 23405-23412
    • Biemel, K.M.1
  • 30
    • 0033492137 scopus 로고    scopus 로고
    • Cross-linking of proteins by Maillard processes: characterization and detection of lysine-arginine cross-links derived from glyoxal and methylglyoxal
    • Lederer M.O., and Klaiber R.G. Cross-linking of proteins by Maillard processes: characterization and detection of lysine-arginine cross-links derived from glyoxal and methylglyoxal. Bioorg. Med. Chem. 7 (1999) 2499-2507
    • (1999) Bioorg. Med. Chem. , vol.7 , pp. 2499-2507
    • Lederer, M.O.1    Klaiber, R.G.2
  • 31
    • 16844380283 scopus 로고    scopus 로고
    • Glucosepane Is a Major Protein Cross-link of the Senescent Human Extracellular Matrix: Relationship with Diabetes
    • Sell D.R., et al. Glucosepane Is a Major Protein Cross-link of the Senescent Human Extracellular Matrix: Relationship with Diabetes. J. Biol. Chem. 280 (2005) 12310-12315
    • (2005) J. Biol. Chem. , vol.280 , pp. 12310-12315
    • Sell, D.R.1
  • 32
    • 23744476305 scopus 로고    scopus 로고
    • The Maillard reaction in eye diseases
    • Stitt A.W. The Maillard reaction in eye diseases. Ann. N. Y. Acad. Sci. 1043 (2005) 582-597
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 582-597
    • Stitt, A.W.1
  • 33
    • 3042704196 scopus 로고    scopus 로고
    • Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis
    • Forbes J.M., et al. Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis. Diabetes 53 (2004) 1813-1823
    • (2004) Diabetes , vol.53 , pp. 1813-1823
    • Forbes, J.M.1
  • 34
    • 23744458810 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products is a promising target of diabetic nephropathy
    • Yamamoto Y., et al. Receptor for advanced glycation end products is a promising target of diabetic nephropathy. Ann. N. Y. Acad. Sci. 1043 (2005) 562-566
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 562-566
    • Yamamoto, Y.1
  • 35
    • 0036430091 scopus 로고    scopus 로고
    • ε-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain
    • ε-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain. Pathol. Int. 52 (2002) 563-571
    • (2002) Pathol. Int. , vol.52 , pp. 563-571
    • Jono, T.1
  • 36
    • 0035003439 scopus 로고    scopus 로고
    • Chemistry and biochemistry of oxidative stress in neurodegenerative disease
    • Sayre L.M., et al. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr. Med. Chem. 8 (2001) 721-738
    • (2001) Curr. Med. Chem. , vol.8 , pp. 721-738
    • Sayre, L.M.1
  • 37
    • 0029113956 scopus 로고
    • Amyloidosis, advanced glycation end products and Alzheimer disease. Comments
    • Smith M.A., et al. Amyloidosis, advanced glycation end products and Alzheimer disease. Comments. Neuroreport 6 (1995) 1595
    • (1995) Neuroreport , vol.6 , pp. 1595
    • Smith, M.A.1
  • 38
    • 0031669073 scopus 로고    scopus 로고
    • Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases
    • Sasaki N., et al. Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases. Am. J. Pathol. 153 (1998) 1149-1155
    • (1998) Am. J. Pathol. , vol.153 , pp. 1149-1155
    • Sasaki, N.1
  • 39
    • 23744471990 scopus 로고    scopus 로고
    • Phototransformations of advanced glycation end products in the human eye lens due to ultraviolet A light irradiation
    • Argirov O.K., et al. Phototransformations of advanced glycation end products in the human eye lens due to ultraviolet A light irradiation. Ann. N. Y. Acad. Sci. 1043 (2005) 166-173
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 166-173
    • Argirov, O.K.1
  • 40
    • 0029789746 scopus 로고    scopus 로고
    • Oxidative posttranslational modifications in Alzheimer's disease: a possible pathogenic role in the formation of senile plaques and neurofibrillary tangles
    • Smith M.A., et al. Oxidative posttranslational modifications in Alzheimer's disease: a possible pathogenic role in the formation of senile plaques and neurofibrillary tangles. Mol. Chem. Neuropathol. 28 (1996) 41-48
    • (1996) Mol. Chem. Neuropathol. , vol.28 , pp. 41-48
    • Smith, M.A.1
  • 41
    • 0032527056 scopus 로고    scopus 로고
    • Advanced glycation endproducts are associated with Hirano bodies in Alzheimer's disease
    • Munch G., et al. Advanced glycation endproducts are associated with Hirano bodies in Alzheimer's disease. Brain Res. 796 (1998) 307-310
    • (1998) Brain Res. , vol.796 , pp. 307-310
    • Munch, G.1
  • 42
    • 23744443807 scopus 로고    scopus 로고
    • Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease
    • Kuhla B., et al. Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease. Ann. N. Y. Acad. Sci. 1043 (2005) 211-216
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 211-216
    • Kuhla, B.1
  • 43
    • 21444449221 scopus 로고    scopus 로고
    • The role of AGEs and AGE inhibitors in diabetic cardiovascular disease
    • Thomas M.C., et al. The role of AGEs and AGE inhibitors in diabetic cardiovascular disease. Curr. Drug Targets 6 (2005) 453-474
    • (2005) Curr. Drug Targets , vol.6 , pp. 453-474
    • Thomas, M.C.1
  • 44
    • 0032720953 scopus 로고    scopus 로고
    • The role of oxidative stress and NF-κB activation in late diabetic complications
    • Mohamed A.K., et al. The role of oxidative stress and NF-κB activation in late diabetic complications. Biofactors 10 (1999) 157-167
    • (1999) Biofactors , vol.10 , pp. 157-167
    • Mohamed, A.K.1
  • 45
    • 0344286498 scopus 로고    scopus 로고
    • Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis
    • Schmidt A.M., et al. Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ. Res. 84 (1999) 489-497
    • (1999) Circ. Res. , vol.84 , pp. 489-497
    • Schmidt, A.M.1
  • 46
    • 1542721873 scopus 로고    scopus 로고
    • Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease
    • Zieman S.J., and Kass D.A. Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease. Drugs 64 (2004) 459-470
    • (2004) Drugs , vol.64 , pp. 459-470
    • Zieman, S.J.1    Kass, D.A.2
  • 47
    • 27744453362 scopus 로고    scopus 로고
    • Understanding RAGE, the receptor for advanced glycation end products
    • Bierhaus A., et al. Understanding RAGE, the receptor for advanced glycation end products. J. Mol. Med. 83 (2005) 876-886
    • (2005) J. Mol. Med. , vol.83 , pp. 876-886
    • Bierhaus, A.1
  • 48
    • 19744364874 scopus 로고    scopus 로고
    • Potential therapeutic implication of nifedipine, a dihydropyridine-based calcium antagonist, in advanced glycation end product (AGE)-related disorders
    • Yamagishi S., et al. Potential therapeutic implication of nifedipine, a dihydropyridine-based calcium antagonist, in advanced glycation end product (AGE)-related disorders. Med. Hypotheses 65 (2005) 392-394
    • (2005) Med. Hypotheses , vol.65 , pp. 392-394
    • Yamagishi, S.1
  • 49
    • 0030031177 scopus 로고    scopus 로고
    • Renal fate of circulating advanced glycated end products (AGE): Evidence for reabsorption and catabolism of AGE-peptides by renal proximal tubular cells
    • Gugliucci A., and Bendayan M. Renal fate of circulating advanced glycated end products (AGE): Evidence for reabsorption and catabolism of AGE-peptides by renal proximal tubular cells. Diabetologia 39 (1996) 149-160
    • (1996) Diabetologia , vol.39 , pp. 149-160
    • Gugliucci, A.1    Bendayan, M.2
  • 50
    • 0031930853 scopus 로고    scopus 로고
    • Renal catabolism of advanced glycation end products: the fate of pentosidine
    • Miyata T., et al. Renal catabolism of advanced glycation end products: the fate of pentosidine. Kidney Int. 53 (1998) 416-422
    • (1998) Kidney Int. , vol.53 , pp. 416-422
    • Miyata, T.1
  • 51
    • 23744506885 scopus 로고    scopus 로고
    • Significance of proximal tubular metabolism of advanced glycation end products in kidney diseases
    • Saito A., et al. Significance of proximal tubular metabolism of advanced glycation end products in kidney diseases. Ann. N. Y. Acad. Sci. 1043 (2005) 637-643
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 637-643
    • Saito, A.1
  • 52
    • 0037377697 scopus 로고    scopus 로고
    • RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy
    • Wendt T.M., et al. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am. J. Pathol. 162 (2003) 1123-1137
    • (2003) Am. J. Pathol. , vol.162 , pp. 1123-1137
    • Wendt, T.M.1
  • 53
    • 0142089894 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders
    • Hudson B.I., et al. Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders. Arch. Biochem. Biophys. 419 (2003) 80-88
    • (2003) Arch. Biochem. Biophys. , vol.419 , pp. 80-88
    • Hudson, B.I.1
  • 54
    • 0030752241 scopus 로고    scopus 로고
    • Relationship between pentosidine levels in serum and urine and activity in rheumatoid arthritis
    • Takahashi M., et al. Relationship between pentosidine levels in serum and urine and activity in rheumatoid arthritis. Br. J. Rheumatol. 36 (1997) 637-642
    • (1997) Br. J. Rheumatol. , vol.36 , pp. 637-642
    • Takahashi, M.1
  • 55
    • 0242273355 scopus 로고    scopus 로고
    • Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis
    • Newkirk M.M., et al. Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis. Arthritis Res. Ther. 5 (2003) R82-R90
    • (2003) Arthritis Res. Ther. , vol.5
    • Newkirk, M.M.1
  • 56
    • 0032918876 scopus 로고    scopus 로고
    • Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study
    • Hart D.J., et al. Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study. Arthritis Rheum. 42 (1999) 17-24
    • (1999) Arthritis Rheum. , vol.42 , pp. 17-24
    • Hart, D.J.1
  • 57
    • 0034960777 scopus 로고    scopus 로고
    • Accumulation of Advanced Glycation End Products Decreases Collagen Turnover by Bovine Chondrocytes
    • DeGroot J., et al. Accumulation of Advanced Glycation End Products Decreases Collagen Turnover by Bovine Chondrocytes. Exp. Cell Res. 266 (2001) 303-310
    • (2001) Exp. Cell Res. , vol.266 , pp. 303-310
    • DeGroot, J.1
  • 58
    • 0031857481 scopus 로고    scopus 로고
    • An update on the epidemiology of knee and hip osteoarthritis with a view to prevention
    • Felson D.T., and Zhang Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum. 41 (1998) 1343-1355
    • (1998) Arthritis Rheum. , vol.41 , pp. 1343-1355
    • Felson, D.T.1    Zhang, Y.2
  • 59
    • 0030858911 scopus 로고    scopus 로고
    • Osteoarthritis
    • Creamer P., and Hochberg M.C. Osteoarthritis. Lancet 350 (1997) 503-508
    • (1997) Lancet , vol.350 , pp. 503-508
    • Creamer, P.1    Hochberg, M.C.2
  • 60
    • 0034671714 scopus 로고    scopus 로고
    • Effect of collagen turnover on the accumulation of advanced glycation end products
    • Verzijl N., et al. Effect of collagen turnover on the accumulation of advanced glycation end products. J. Biol. Chem. 275 (2000) 39027-39031
    • (2000) J. Biol. Chem. , vol.275 , pp. 39027-39031
    • Verzijl, N.1
  • 61
    • 0034283577 scopus 로고    scopus 로고
    • Age-related accumulation of Maillard reaction products in human articular cartilage collagen
    • Verzijl N., et al. Age-related accumulation of Maillard reaction products in human articular cartilage collagen. Biochem. J. 350 (2000) 381-387
    • (2000) Biochem. J. , vol.350 , pp. 381-387
    • Verzijl, N.1
  • 62
    • 0028364606 scopus 로고
    • Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors
    • El Khoury J., et al. Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors. J. Biol. Chem. 269 (1994) 10197-10200
    • (1994) J. Biol. Chem. , vol.269 , pp. 10197-10200
    • El Khoury, J.1
  • 63
    • 0029366113 scopus 로고
    • Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex
    • Vlassara H., et al. Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex. Mol. Med. 1 (1995) 634-646
    • (1995) Mol. Med. , vol.1 , pp. 634-646
    • Vlassara, H.1
  • 64
    • 0001263746 scopus 로고    scopus 로고
    • Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins
    • Li Y.M., et al. Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 11047-11052
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 11047-11052
    • Li, Y.M.1
  • 65
    • 0036180791 scopus 로고    scopus 로고
    • CD36, serves as a receptor for advanced glycation endproducts (AGE)
    • Ohgami N., et al. CD36, serves as a receptor for advanced glycation endproducts (AGE). J. Diabetes Complications 16 (2002) 56-59
    • (2002) J. Diabetes Complications , vol.16 , pp. 56-59
    • Ohgami, N.1
  • 66
    • 26444478269 scopus 로고    scopus 로고
    • Advanced glycation end products and RAGE: A common thread in aging, diabetes, neurodegeneration, and inflammation
    • Ramasamy R., et al. Advanced glycation end products and RAGE: A common thread in aging, diabetes, neurodegeneration, and inflammation. Glycobiology 15 (2005) 16R-28R
    • (2005) Glycobiology , vol.15
    • Ramasamy, R.1
  • 67
    • 21644441444 scopus 로고    scopus 로고
    • Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control
    • Pullerits R., et al. Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control. Arthritis Res. Ther. 7 (2005) R817-R824
    • (2005) Arthritis Res. Ther. , vol.7
    • Pullerits, R.1
  • 68
    • 33745208171 scopus 로고    scopus 로고
    • Mjalli, A.M.M. et al. (2005) RAGE antagonists as agents to reverse amyloidosis and associated diseases. Patent No. 2004-US16104; Chem. Abstr. 2005:14210
  • 69
    • 0025540553 scopus 로고
    • Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes
    • Mullarkey C.J., et al. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem. Biophys. Res. Commun. 173 (1990) 932-939
    • (1990) Biochem. Biophys. Res. Commun. , vol.173 , pp. 932-939
    • Mullarkey, C.J.1
  • 70
    • 23744458810 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products is a promising target of diabetic nephropathy
    • Yamamoto Y., et al. Receptor for advanced glycation end products is a promising target of diabetic nephropathy. Ann. N. Y. Acad. Sci. 1043 (2005) 562-566
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 562-566
    • Yamamoto, Y.1
  • 71
    • 0034992635 scopus 로고    scopus 로고
    • Increased protein glycation in cerebrospinal fluid of Alzheimer's disease
    • Shuvaev V.V., et al. Increased protein glycation in cerebrospinal fluid of Alzheimer's disease. Neurobiol. Aging 22 (2001) 397-402
    • (2001) Neurobiol. Aging , vol.22 , pp. 397-402
    • Shuvaev, V.V.1
  • 72
    • 0032752314 scopus 로고    scopus 로고
    • Advanced glycation end products induce apoptosis and procoagulant activity in cultured human umbilical vein endothelial cells
    • Min C., et al. Advanced glycation end products induce apoptosis and procoagulant activity in cultured human umbilical vein endothelial cells. Diabetes Res. Clin. Pract. 46 (1999) 197-202
    • (1999) Diabetes Res. Clin. Pract. , vol.46 , pp. 197-202
    • Min, C.1
  • 73
    • 0037455982 scopus 로고    scopus 로고
    • Genotoxicity of advanced glycation end products in mammalian cells
    • Stopper H., et al. Genotoxicity of advanced glycation end products in mammalian cells. Cancer Lett. 190 (2003) 151-156
    • (2003) Cancer Lett. , vol.190 , pp. 151-156
    • Stopper, H.1
  • 74
    • 19944424142 scopus 로고    scopus 로고
    • Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease
    • Lue L.F., et al. Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease. Curr. Drug Targets CNS Neurol. Disord. 4 (2005) 249-266
    • (2005) Curr. Drug Targets CNS Neurol. Disord. , vol.4 , pp. 249-266
    • Lue, L.F.1
  • 75
    • 21544477514 scopus 로고    scopus 로고
    • At Least 2 Distinct Pathways Generating Reactive Oxygen Species Mediate Vascular Cell Adhesion Molecule-1 Induction by Advanced Glycation End Products
    • Basta G., et al. At Least 2 Distinct Pathways Generating Reactive Oxygen Species Mediate Vascular Cell Adhesion Molecule-1 Induction by Advanced Glycation End Products. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 1401-1407
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 1401-1407
    • Basta, G.1
  • 76
    • 14044268796 scopus 로고    scopus 로고
    • Atherosclerosis and restenosis: Is there a role for RAGE? Curr
    • Nawroth P., et al. Atherosclerosis and restenosis: Is there a role for RAGE? Curr. Diab. Rep. 5 (2005) 11-16
    • (2005) Diab. Rep. , vol.5 , pp. 11-16
    • Nawroth, P.1
  • 77
    • 4043058031 scopus 로고    scopus 로고
    • Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
    • Basta G., et al. Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes. Cardiovasc. Res. 63 (2004) 582-592
    • (2004) Cardiovasc. Res. , vol.63 , pp. 582-592
    • Basta, G.1
  • 78
    • 0034695098 scopus 로고    scopus 로고
    • The biology of the receptor for advanced glycation end products and its ligands
    • Schmidt A.M., et al. The biology of the receptor for advanced glycation end products and its ligands. Biochim Biophys Acta. 1498 (2000) 99-111
    • (2000) Biochim Biophys Acta. , vol.1498 , pp. 99-111
    • Schmidt, A.M.1
  • 79
    • 23744439419 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration
    • Moreira P.I., et al. Oxidative stress and neurodegeneration. Ann. N. Y. Acad. Sci. 1043 (2005) 545-552
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 545-552
    • Moreira, P.I.1
  • 80
    • 1842453324 scopus 로고    scopus 로고
    • Oxidative stress signalling in Alzheimer's disease
    • Zhu X., et al. Oxidative stress signalling in Alzheimer's disease. Brain Res. 1000 (2004) 32-39
    • (2004) Brain Res. , vol.1000 , pp. 32-39
    • Zhu, X.1
  • 81
    • 0029817298 scopus 로고    scopus 로고
    • Inhibitors of the Maillard reaction: potential in the treatment of Alzheimer's disease
    • Colaco C.A.L.S., and Harrington C.R. Inhibitors of the Maillard reaction: potential in the treatment of Alzheimer's disease. CNS Drugs 6 (1996) 167-177
    • (1996) CNS Drugs , vol.6 , pp. 167-177
    • Colaco, C.A.L.S.1    Harrington, C.R.2
  • 82
    • 0026529770 scopus 로고
    • Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen
    • Blakytny R., and Harding J.J. Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. Exp. Eye Res. 54 (1992) 509-518
    • (1992) Exp. Eye Res. , vol.54 , pp. 509-518
    • Blakytny, R.1    Harding, J.J.2
  • 83
    • 16344393699 scopus 로고    scopus 로고
    • Beneficial effects of aminoguanidine on the cardiovascular system of diabetic rats
    • Stadler K., et al. Beneficial effects of aminoguanidine on the cardiovascular system of diabetic rats. Diabetes Metab. Res. Rev. 21 (2005) 189-196
    • (2005) Diabetes Metab. Res. Rev. , vol.21 , pp. 189-196
    • Stadler, K.1
  • 84
    • 10744223527 scopus 로고    scopus 로고
    • Randomized Trial of an Inhibitor of Formation of Advanced Glycation End Products in Diabetic Nephropathy
    • Bolton W.K., et al. Randomized Trial of an Inhibitor of Formation of Advanced Glycation End Products in Diabetic Nephropathy. Am. J. Nephrol. 24 (2004) 32-40
    • (2004) Am. J. Nephrol. , vol.24 , pp. 32-40
    • Bolton, W.K.1
  • 85
    • 0142122031 scopus 로고    scopus 로고
    • Angiotensin II receptor blockers and angiotensin converting enzyme inhibitors: implication of radical scavenging and transition metal chelation in inhibition of advanced glycation end product formation
    • Miyata T., and van Ypersele de Strihou C. Angiotensin II receptor blockers and angiotensin converting enzyme inhibitors: implication of radical scavenging and transition metal chelation in inhibition of advanced glycation end product formation. Arch. Biochem. Biophys. 419 (2003) 50-54
    • (2003) Arch. Biochem. Biophys. , vol.419 , pp. 50-54
    • Miyata, T.1    van Ypersele de Strihou, C.2
  • 86
    • 28844433635 scopus 로고    scopus 로고
    • The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
    • Shaw R.J., et al. The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin. Science 310 (2005) 1642-1646
    • (2005) Science , vol.310 , pp. 1642-1646
    • Shaw, R.J.1
  • 87
    • 33745220884 scopus 로고    scopus 로고
    • Kinetics and mechanism of the reaction of metformin with methylglyoxal
    • Battah S., et al. Kinetics and mechanism of the reaction of metformin with methylglyoxal. Int. Congr. Ser. 1245 (2002) 355-356
    • (2002) Int. Congr. Ser. , vol.1245 , pp. 355-356
    • Battah, S.1
  • 88
    • 0031054249 scopus 로고    scopus 로고
    • In vitro kinetic studies of formation of antigenic advanced glycation end products (AGEs). Novel inhibition of post-Amadori glycation pathways
    • Booth A.A., et al. In vitro kinetic studies of formation of antigenic advanced glycation end products (AGEs). Novel inhibition of post-Amadori glycation pathways. J. Biol. Chem. 272 (1997) 5430-5437
    • (1997) J. Biol. Chem. , vol.272 , pp. 5430-5437
    • Booth, A.A.1
  • 89
    • 0142211275 scopus 로고    scopus 로고
    • Pyridoxamine Traps Intermediates in Lipid Peroxidation Reactions in vivo: Evidence on the Role of Lipids in Chemical Modification of Protein and Development of Diabetic Complications
    • Metz T.O., et al. Pyridoxamine Traps Intermediates in Lipid Peroxidation Reactions in vivo: Evidence on the Role of Lipids in Chemical Modification of Protein and Development of Diabetic Complications. J. Biol. Chem. 278 (2003) 42012-42019
    • (2003) J. Biol. Chem. , vol.278 , pp. 42012-42019
    • Metz, T.O.1
  • 90
    • 23844460628 scopus 로고    scopus 로고
    • Pyridoxamine as a multifunctional pharmaceutical: Targeting pathogenic glycation and oxidative damage
    • Voziyan P.A., and Hudson B.G. Pyridoxamine as a multifunctional pharmaceutical: Targeting pathogenic glycation and oxidative damage. Cell. Mol. Life Sci. 62 (2005) 1671-1681
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 1671-1681
    • Voziyan, P.A.1    Hudson, B.G.2
  • 91
    • 12144257117 scopus 로고    scopus 로고
    • Clinical studies of advanced glycation end product inhibitors and diabetic kidney disease
    • Williams Mark E. Clinical studies of advanced glycation end product inhibitors and diabetic kidney disease. Curr. Diab. Rep. 4 (2004) 441-446
    • (2004) Curr. Diab. Rep. , vol.4 , pp. 441-446
    • Williams Mark, E.1
  • 92
    • 23744514571 scopus 로고    scopus 로고
    • Pyridoxamine: The many virtues of a Maillard reaction inhibitor
    • Voziyan P.A., and Hudson B.G. Pyridoxamine: The many virtues of a Maillard reaction inhibitor. Ann. N. Y. Acad. Sci. 1043 (2005) 807-816
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 807-816
    • Voziyan, P.A.1    Hudson, B.G.2
  • 93
    • 0029111529 scopus 로고
    • Non-enzymic glycosylation of the dipeptide L-carnosine, a potential anti-protein-crosslinking agent
    • Hipkiss A.R., et al. Non-enzymic glycosylation of the dipeptide L-carnosine, a potential anti-protein-crosslinking agent. FEBS Lett. 371 (1995) 81-85
    • (1995) FEBS Lett. , vol.371 , pp. 81-85
    • Hipkiss, A.R.1
  • 94
    • 2942652420 scopus 로고    scopus 로고
    • Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes
    • Babizhayev M.A., et al. Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes. Drugs R D. 5 (2004) 125-139
    • (2004) Drugs R D. , vol.5 , pp. 125-139
    • Babizhayev, M.A.1
  • 95
    • 0141457973 scopus 로고    scopus 로고
    • Acrolein-sequestering ability of endogenous dipeptides: Characterization of carnosine and homocarnosine/acrolein adducts by electrospray ionization tandem mass spectrometry
    • Carini M., et al. Acrolein-sequestering ability of endogenous dipeptides: Characterization of carnosine and homocarnosine/acrolein adducts by electrospray ionization tandem mass spectrometry. J. Mass Spectrom. 38 (2003) 996-1006
    • (2003) J. Mass Spectrom. , vol.38 , pp. 996-1006
    • Carini, M.1
  • 96
    • 2942729775 scopus 로고    scopus 로고
    • Metals in our minds: therapeutic implications for neurodegenerative disorders
    • Doraiswamy P.M., and Finefrock A.E. Metals in our minds: therapeutic implications for neurodegenerative disorders. Lancet Neurol. 3 (2004) 431-434
    • (2004) Lancet Neurol. , vol.3 , pp. 431-434
    • Doraiswamy, P.M.1    Finefrock, A.E.2
  • 97
    • 0033373789 scopus 로고    scopus 로고
    • The pivotal role of iron in NF-kB activation and nigrostriatal dopaminergic neurodegeneration: Prospects for neuroprotection in Parkinson's disease with iron chelators
    • Youdim M.B.H., et al. The pivotal role of iron in NF-kB activation and nigrostriatal dopaminergic neurodegeneration: Prospects for neuroprotection in Parkinson's disease with iron chelators. Ann. N. Y. Acad. Sci. 890 (1999) 7-25
    • (1999) Ann. N. Y. Acad. Sci. , vol.890 , pp. 7-25
    • Youdim, M.B.H.1
  • 98
    • 0035966113 scopus 로고    scopus 로고
    • Chelating activity of advanced glycation end-product inhibitors
    • Price D.L., et al. Chelating activity of advanced glycation end-product inhibitors. J. Biol. Chem. 276 (2001) 48967-48972
    • (2001) J. Biol. Chem. , vol.276 , pp. 48967-48972
    • Price, D.L.1
  • 99
    • 0036668214 scopus 로고    scopus 로고
    • Inhibitor for advanced glycation end products formation attenuates hypertension and oxidative damage in genetic hypertensive rats
    • Mizutani K., et al. Inhibitor for advanced glycation end products formation attenuates hypertension and oxidative damage in genetic hypertensive rats. J. Hypertens. 20 (2002) 1607-1614
    • (2002) J. Hypertens. , vol.20 , pp. 1607-1614
    • Mizutani, K.1
  • 100
    • 33644843826 scopus 로고    scopus 로고
    • Role of the renin-angiotensin system in the endocrine pancreas: Implications for the development of diabetes
    • Tikellis C., et al. Role of the renin-angiotensin system in the endocrine pancreas: Implications for the development of diabetes. Int. J. Biochem. Cell Biol. 38 (2006) 737-751
    • (2006) Int. J. Biochem. Cell Biol. , vol.38 , pp. 737-751
    • Tikellis, C.1
  • 101
    • 28444472740 scopus 로고    scopus 로고
    • Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy
    • Forbes J.M., et al. Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy. J. Am. Soc. Nephrol. 16 (2005) 2363-2372
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 2363-2372
    • Forbes, J.M.1
  • 102
    • 20444407658 scopus 로고    scopus 로고
    • Prevention and treatment of diabetic nephropathy
    • Wittmann I., et al. Prevention and treatment of diabetic nephropathy. Diabetes Res. Clin. Pract. 68 Suppl. 1 (2005) S36-S42
    • (2005) Diabetes Res. Clin. Pract. , vol.68 , Issue.SUPPL. 1
    • Wittmann, I.1
  • 103
    • 27644519247 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers for prevention and treatment of nephropathy associated with type 2 diabetes mellitus
    • Hughes D.B., and Britton M.L. Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers for prevention and treatment of nephropathy associated with type 2 diabetes mellitus. Pharmacotherapy 25 (2005) 1602-1620
    • (2005) Pharmacotherapy , vol.25 , pp. 1602-1620
    • Hughes, D.B.1    Britton, M.L.2
  • 104
    • 0037251741 scopus 로고    scopus 로고
    • Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes
    • Aronson D. Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes. J. Hypertens. 21 (2003) 3-12
    • (2003) J. Hypertens. , vol.21 , pp. 3-12
    • Aronson, D.1
  • 105
    • 0037376556 scopus 로고    scopus 로고
    • AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats
    • Yang S., et al. AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats. Arch. Biochem. Biophys. 412 (2003) 42-46
    • (2003) Arch. Biochem. Biophys. , vol.412 , pp. 42-46
    • Yang, S.1
  • 106
    • 2342648312 scopus 로고    scopus 로고
    • The AGE of the matrix: chemistry, consequence and cure
    • DeGroot J. The AGE of the matrix: chemistry, consequence and cure. Curr. Opin. Pharmacol. 4 (2004) 301-305
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 301-305
    • DeGroot, J.1
  • 107
    • 0142121508 scopus 로고    scopus 로고
    • Therapeutic potential of breakers of advanced glycation end product-protein crosslinks
    • Vasan S., et al. Therapeutic potential of breakers of advanced glycation end product-protein crosslinks. Arch. Biochem. Biophys. 419 (2003) 89-96
    • (2003) Arch. Biochem. Biophys. , vol.419 , pp. 89-96
    • Vasan, S.1
  • 108
    • 0035949502 scopus 로고    scopus 로고
    • Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
    • Kass D.A., et al. Improved arterial compliance by a novel advanced glycation end-product crosslink breaker. Circulation 104 (2001) 1464-1470
    • (2001) Circulation , vol.104 , pp. 1464-1470
    • Kass, D.A.1
  • 109
    • 16244371321 scopus 로고    scopus 로고
    • The Effect of Alagebrium Chloride (ALT-711), a Novel Glucose Cross-Link Breaker, in the Treatment of Elderly Patients With Diastolic Heart Failure
    • Little W.C., et al. The Effect of Alagebrium Chloride (ALT-711), a Novel Glucose Cross-Link Breaker, in the Treatment of Elderly Patients With Diastolic Heart Failure. J. Card. Fail. 11 (2005) 191-195
    • (2005) J. Card. Fail. , vol.11 , pp. 191-195
    • Little, W.C.1
  • 110
    • 10644246127 scopus 로고    scopus 로고
    • Advanced glycation end-product cross-link breakers: A novel approach to cardiovascular pathologies related to the aging process
    • Bakris G.L., et al. Advanced glycation end-product cross-link breakers: A novel approach to cardiovascular pathologies related to the aging process. Am. J. Hypertens. 17 (2004) 23S-30S
    • (2004) Am. J. Hypertens. , vol.17
    • Bakris, G.L.1


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