Advanced glycation and endothelial functions: A link towards vascular complications in diabetes

Life Sciences

Volumn 76, Issue 7, 2004, Pages 715-730

  Rojas, Armando ^a   Morales, Miguel A ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b Lab Farmacodinamia Y F   (Chile)

Author keywords

Advanced glycation; Diabetes; Endothelium; Vascular complications

Indexed keywords

ALDOSE REDUCTASE INHIBITOR; AMINOGUANIDINE; AMYLOID BETA PROTEIN; BENFOTIAMINE; BETA2 INTEGRIN; CELL ADHESION MOLECULE; GLUCOSE; ISRADIPINE; KEISHI BUKURYO GAN; LACIDIPINE; METFORMIN; NIFEDIPINE; NITRIC OXIDE; OLMESARTAN; PROSTACYCLIN; RAMIPRIL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TEMOCAPRILAT;

AMADORI REARRANGEMENT; ANGIOGENESIS; ANTIOXIDANT ACTIVITY; BLOOD VESSEL PERMEABILITY; CARDIOVASCULAR RISK; CELL MIGRATION; CHINESE MEDICINE; CORONARY ARTERY ATHEROSCLEROSIS; DIABETIC MICROANGIOPATHY; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; GLYCATION; HUMAN; MICROVASCULARIZATION; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PROTEIN EXPRESSION; REACTION ANALYSIS; RECEPTOR OCCUPANCY; RETINA DEGENERATION; RISK FACTOR; SHORT SURVEY; SIGNAL TRANSDUCTION; WOUND HEALING IMPAIRMENT;

EID: 9644308246     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.09.011     Document Type: Review

References (121)

1. A. Abaci, A. Oguzhan, S. Kahraman, N.K. Eryol, S. Unal, H. Arinc, and A. Ergin Effect of diabetes mellitus on formation of coronary collateral vessels Circulation 99 1999 2239 2242
2. E. Abdel-Rahman, and W.K. Bolton Pimagedine: a novel therapy for diabetic nephropathy Experts Opinion on Investigational Drugs 11 2002 565 574
3. M. Ahmed, S.R. Thorpe, and J.W. Bynes Identification of Nε-(carboxymethyl)lysine as a degradation product of fructoselysine in glycated proteins J. Biological Chemistry 61 1986 4889 4894
4. D. Aronson, and E.J. Rayfield How hyperglycemia promotes atherosclerosis: molecular mechanisms Cardiovascular Diabetology 1 2002 1 10
5. M. Asif, J. Egan, S. Vasan, G.N. Jyothirmayi, M.R. Masurekar, S. Lopez, C. Williams, R.L. Torres, D. Wagle, P. Ulrich, A. Cerami, M. Brines, and T.J. Regan An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness Proceedings National Academy of Sciences USA 97 2000 2809 28013
6. G. Basta, G. Lazzerini, M. Massaro, T. Simoncini, P. Tanganelli, C. Fu, T. Kislinger, D.M. Stern, A.M. Schmidt, and R. De Caterina Advanced glycation end products activate endothelium through signal-transduction receptor RAGE. A mechanism for amplification of inflammatory responses Circulation 105 2002 816 822
7. J.W. Baynes, and S.R. Thorpe Role of oxidative stress in diabetic complications. A new perspective on an old paradigm Diabetes 48 1999 1 9
8. H. Beekhuizen, A.J. Corse van Tilburg, and R. Furth Characterization of monocyte adherence to human macrovascular and microvascular endothelial cells Journal of Immunology 145 1990 510 518
9. A. Bierhaus, T. Illmer, M. Kasper, T. Luther, P. Quehenberger, H. Tritschler, P. Wahl, R. Ziegler, M. Müller, and P.P. Nawroth Advanced glycation endproducts (AGEs) mediated induction of tissue factor in cultured endothelial cells is dependent on RAGE Circulation 96 1997 2262 2271
10. A. Bierhaus, S. Schiekofer, M. Schwaninger, M. Andrassy, P.M. Humpert, J. Chen, M. Hong, T. Luther, T. Thomas, I. Klöting, M. Morcos, M. Hofmann, H. Tritschler, B. Weigle, M. Kasper, M. Smith, G. Perry, A.M. Schmidt, D.M. Stern, H.A Häring, E. Schleicher, and P.P. Nawroth Diabetes-associated sustained activation of the transcription factor nuclear factor-κB Diabetes 50 2001 2792 2808
11. E. Bierman George Lyman Duff Memorial Lecture: atherogenesis in diabetes Arteriosclerosis and Thrombosis 12 1992 647 656
12. E. Bonnardel-Phu, J.L. Wautier, A.M. Schmidt, C. Avila, and E. Vicaut Acute modulation of albumin microvascular leakage by advanced glycation end products in microcirculation of diabetic rats in vivo Diabetes 48 1999 2052 2058
13. E. Bonnardel-Phu, J.L. Wautier, and E. Vicaut Advanced glycation end products are involved in microvascular permeability changes observed in microcirculation of diabetic rats in vivo Malaties Vascular 25 2000 122 127
14. D. Bonnefont-Rousselot Antioxidant and anti-AGE therapeutics: evaluation and perspectives Social Biology 195 2001 391 398
15. J. Brett, A.M. Schmidt, S.D. Yan, Y.S. Zou, E. Weidman, D. Pinsky, R. Nowygrod, M. Neeper, C. Przysiecki, and A. Shaw Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues American Journal of Pathology 143 1993 1699 1712
16. M. Brownlee, A. Cerami, and H. Vlassara Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications New England Journal of Medicine 318 1988 1315 1321
17. M. Brownlee, H. Vlassara, A. Kooney, P. Ulrich, and A. Cerami Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking Science 232 1986 1629 1632
18. M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
19. R. Bucala, K.J. Tracey, and A. Cerami Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilation in experimental diabetes The Journal of Clinical Investigation 87 1991 432 438
20. R. Bucala, and A. Cerami Advanced glycosylation: chemistry, biology, and implications for diabetes and aging Advances in Pharmacology 23 1992 1 34
21. H.F. Bunn, K.H. Gabbay, and P.M. Gallop The glycosylation of hemoglobin: relevance to diabetes mellitus Science 200 1978 21 27
22. N.E. Cameron, S.E. Eaton, M.A. Cotter, and S. Tesfaye Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy Diabetologia 44 2001 1973 1988
23. R. Candido, J.M. Forbes, M.C. Thomas, V. Thallas, R.G. Dean, W.C. Burns, C. Tikellis, R.H. Ritchie, S.M. Twigg, M.E. Cooper, and L.M. Burrell A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes Circulation Research 92 2003 785 792
24. U. Chakravarthy, R.G. Hayes, A.W. Stitt, E. McAuley, and D.B. Archer Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products Diabetes 47 1998 945 952
25. T. Chavakis, A. Bierhaus, N. Al-Fakhri, D. Schneider, S. Witte, T. Linn, M. Nagashima, J. Morser, B. Arnold, K.T. Preissner, and P.P. Nawroth The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment Journal of Experimental Medicine 198 2003 1501 1515
26. H.K. Cho, H. Kozu, G.A. Peyman, G.J. Parry, and B. Khoobehi The effect of aminoguanidine on the blood-retinal barrier in streptozocin-induced diabetic rats Ophthalmic Surgery 22 1990 44 47
27. D.B. Cines, E.S. Pollak, C.A. Buck, J. Loscalzo, G.A. Zimmerman, R.P. Mc Ever, J.S. Pober, T.M. Wick, B.A. Konkle, B.S. Schwartz, E.S. Barnathan, K.R. McCrae, B.A. Hug, A.M. Schmidt, and D.M. Stern Endothelial cells in physiology and in the pathophysiology of vascular disorders Blood 91 1998 3527 3561
28. R. Deane, S. Du Yan, R.K. Submamaryan, B. LaRue, S. Jovanovic, E. Hogg, D. Welch, L. Manness, C. Lin, J. Yu, H. Zhu, J. Ghiso, B. Frangione, A. Stern, A.M. Schmidt, D.L. Armstrong, B. Arnold, B. Liliensiek, P. Nawroth, F. Hofman, M. Kindy, D. Stern, and B. Zlokovic RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain Nature Medicine 9 2003 907 913
29. P.J. Dickinson, A.L. Carrington, G.S. Frost, and A.J. Boulton Neurovascular disease, antioxidants and glycation in diabetes Diabetes Metabolism Research Reviews 18 2002 260 272
30. H. Dorchy Characterization of early stages of diabetic retinopathy. Importance of the breakdown of the blood-retinal barrier Diabetes Care 16 1993 1212 1214
31. D.G. Dyer, J.A. Dunn, S.R. Thorpe, K.E. Bailie, T.J. Lyons, D.R. McCance, and J.W. Baynes Accumulation of Maillard reaction products in skin collagen in diabetes and aging The Journal of Clinical Investigation 91 1993 2463 2469
32. C. Fiuza, M. Bustin, S. Talwar, M. Tropea, E. Gerstenberger, J.H. Shelhamer, and A.F. Suffredini Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells Blood 101 2003 2652 2660
33. R. Giri, S. Selvaraj, C.A. Miller, F. Hofman, S.D. Yan, D. Stern, B.V. Zlokovic, and V.K. Kalra Effect of endothelial cell polarity on β-amyloid-induced migration of monocytes across normal and AD endothelium American Journal of Physiology and Cellular Physiology 283 2002 C895 C904
34. R. Giri, Y. Shen, M. Stins, S. Du Yan, A.M. Schmidt, D. Stern, K.S. Kim, B. Zlokovic, and V.K. Kalra β-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1 American Journal of Physiology and Cellular Physiology 279 2000 C1772 C1781
35. H.P. Hammes, X. Du, D. Edelstein, T. Taguchi, T. Matsumura, Q. Ju, J. Lin, A. Bierhaus, P. Nawroth, D. Hannak, M. Neumaier, R. Bergfeld, I. Giardino, and M. Brownlee Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy Nature Medicine 9 2003 294 299
36. M.A. Hofmann, S. Drury, C. Fu, W. Qu, A. Taguchi, Y. Lu, C. Avila, N. Kambham, A. Bierhaus, and P. Nawroth RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell. 97 1999 889 901
37. Y. Ido, K.C. Chang, W.S. Lejeune, R.J. Bjercke, K.M. Reiser, J.R. Williamson, and R.G. Tilton Vascular dysfunction induced by AGE is mediated by VEGF via mechanisms involving reactive oxygen species, guanylate cyclase, and protein kinase C Microcirculation 8 2001 251 263
38. G. King, and M. Brownlee The cellular and molecular mechanisms of diabetic complications Endocrinology and Metabolism Clinics of North America 25 1996 255 270
39. H.M. Knott, B.E. Brown, M.J. Davies, and R.T. Dean Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles European Journal of Biochemistry 270 2003 3572 3582
40. A. Krolewski, E. Kosinski, J. Warram, O. Leland, E. Busick, A. Asmal, A. Rand, A. Christlieb, R. Bradley, and C. Kahn Magnitude and determinants of coronary artery disease in juvenile-onset, insulin-dependent diabetes mellitus American Journal of Cardiology 59 1987 750 755
41. T. Kunt, T. Forst, O. Harzer, G. Buchert, A. Pfutzner, M. Lobig, A. Zschabitz, E. Stofft, M. Engelbach, and J. Beyer The influence of advanced glycation endproducts (AGE) on the expression of human endothelial adhesion molecules Experimental and Clinical Endocrinology and Diabetes 106 1998 183 188
42. T. Kunt, T. Forst, A. Wilhem, H. Tritschle, A. Pfuetzner, O. Harzer, M. Engelbach, M. Zscaebitz, E. Stoff, and J. Beyer α-Lipoic acid reduces expression of vascular cell adhesion molecule-1 and endothelial adhesion of human monocytes after stimulation with advanced glycation end products Clinical Science 96 1999 75 82
43. H.M. Lander, J.M. Tauras, J.S. Ogiste, R.A. Moss, and A.M. Schmidt Activation of the receptor for advanced glycation endproducts triggers a MAP kinase pathway regulated by oxidant stress Journal of Biological Chemistry 272 1997 17810 17814
44. F. Ledl, and E. Schleicher New aspects of the Maillard reaction in foods and in the human body Angew. Chem. Int. Ed. Engl. 29 1990 565 594
45. J. Li, and A.M. Schmidt Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products Journal of Biological Chemistry 272 1997 16498 16506
46. Y.M. Li, T. Mitsuhashi, D. Wojciechowicz, N. Shimizu, J. Li, A. Stitt, C. He, D. Banerjee, and H. Vlassara Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins Proceedings National Academy of Sciences USA 93 1991 11047 11052
47. Y.M. Li, A.X. Tan, and H. Vlassara Antibacterial activity of lysozyme and lactoferrin is inhibited by binding of advanced glycation-modified proteins to a conserved motif Nature Medicine 1 1995 1057 1061
48. L.C. Maillard Action des acides amines sur les sucres: formation des melaniodines par voie methodique C.R. Academy Sciences 154 1912 66 68
49. D.R. McCance, D.G. Dyer, J.A. Dunn, K.E. Bailie, S.R. Thrope, J.W. Baynes, and T.J. Lyons Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus The Journal of Clinical Investigation 91 1993 2470 2478
50. C. Michiels Endothelial cell functions Journal of Cellular Physiology 196 2003 430 443
51. T. Miyata, C. van Ypersele de Strihou, Y. Ueda, K. Ichimori, R. Inagi, H. Onogi, N. Ishikawa, M. Nangaku, and K. Kurokawa Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: biochemical mechanisms Journal American Society Nephrology 13 2002 q2478 q2487
52. V.M. Monnier, and A. Cerami Nonenzymatic browning in vivo: possible processes for aging of long-lived proteins Science 211 1981 491 493
53. S. Müller, P. Scaffidi, B. Degryse, D. Bonaldi, L. Ronfani, A. Agresti, M. Beltrame, and M.E. Bianchi The double life of HMGB1 chromatin protein: architectural factor and extracellular signal The EMBO Journal 20 2001 4337 4340
54. T. Nakagawa, T. Yokozawa, K. Terasawa, and K. Nakanishi Therapeutic usefulness of Keishi-bukuryo-gan for diabetic nephropathy Journal of Pharmacy and Pharmacology 55 2003 219 227
55. N. Nakamura, K. Yamazaki, A. Satoh, M. Urakaze, M. Kobayashi, H. Yamabe, H. Osawa, K. Shirato, T. Sugawara, M. Nakamura, M. Tamura, and K. Okumura Effects of eparlestat on plasma levels of advanced glycation end products in patients with type 2 diabetes In Vivo 17 2003 177 180
56. M. Nakayama, G. Izumi, Y. Nemoto, K. Shibata, T. Hasegawa, M. Numata, K. Wang, Y. Kawaguchi, and T. Hosoya Suppression of N(epsilon)-(carboxymethyl) lysine generation by the antioxidant N-acetylcysteine Peritoneal Dialysis International 19 1999 207 210
57. M. Nangaku, T. Miyata, T. Sada, M. Mizuno, R. Inagi, Y. Ueda, N. Ishikawa, H. Yuzawa, H. Koike, C. van Ypersele de Strihou, and K. Kurokawa Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end products and improve renal damage in a type 2 diabetic nephropathy rat model Journal American Society of Nephrology 14 2003 1212 1222
58. M. Navab, S.Y. Hama, T.B. Nguyen, and A.M. Fogelman Monocyte adhesion and transmigration in atherosclerosis Coronary Artery Disease 5 1994 198 204
59. M. Neeper, A.M. Schmidt, J. Brett, S.D. Yan, F. Wang, Y.C. Pan, K. Elliston, D. Stern, and A. Shaw Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins Journal of Biological Chemistry 267 1992 14998 15004
60. B.O. Nilsson Biological effects of aminoguanidine: an update Inflammation Research 48 1999 509 515
61. N. Ohgami, R. Nagama, M. Ikemoto, H. Arai, A. Kuniyasu, S. Horiuchi, and H. Nakayama CD36, a member of the class B scavenger receptor family, as a receptor for advanced glycation end products Journal of Biological Chemistry 276 2001 3195 3202
62. T. Okamoto, S. Tanaka, A.C. Stan, T. Koike, M. Kase, Z. Makita, H. Sawa, and K. Nagashima Advanced glycation end products induce angiogenesis in vivo Microvascular Research 63 2002 186 195
63. T. Okamoto, S. Yamagishi, Y. Inagaki, S. Amano, K. Koga, R. Abe, M. Takeuchi, S. Ohno, A. Yoshimura, and Z. Makita Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin The FASEB Journal 16 2002 1928 1930
64. K. Otero, F. Martínez, A. Beltran, D. González, B. Herrera, G. Quintero, and A. Rojas Albumin-derived advanced glycation end-products trigger the disruption of the vascular endothelial-complex in cultured human and murine endothelial cells Biochemical Journal 359 2001 567 574
65. R.M.J. Palmer, A.G. Ferrige, and S. Moncada Nitric oxide release accounts for the biological activity of endothelial-derived relaxing factor Nature 327 1987 524 526
66. L. Park, K.G. Raman, K.J. Lee, Y. Lu, L.J. Ferran Jr., W.S. Chow, D. Stern, and A.M. Schmidt Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts Nature Medicine 4 1998 1025 1031
67. H.H. Parving, and N. Rossing Simultaneous determination of the transcapillary escape rate of albumin and IgG in normal and long-term juvenile diabetic subjects Scandinavian Journal Clinical and Laboratory Investigation 32 1973 239 244
68. P. Quehenberger, A. Bierhaus, P. Fasching, C. Muellner, M. Klevesath, M. Hong, G. Stier, M. Sattler, E. Schleicher, W. Speiser, and P.P. Nawroth Endothelin 1 transcription is controlled by nuclear factor-κB in AGE-stimulated cultured endothelial cells Diabetes 49 2000 1561 1570
69. V. Rattan, Y. Shen, C. Sultana, D. Kumar, and V.K. Kalra Diabetic RBC-induced oxidant stress leads to transendothelial migration of monocyte-like HL-60 cells American Journal of Physiology 273 1997 E369 E375
70. J.E.B. Reusch Aterosclerosis y diabetes. Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose? The Journal of Clinical Investigation 112 2003 986 988
71. U. Ritthaler, H. Roth, A. Bierhaus, R. Ziegler, A.M. Schmidt, R. Waldherr, P. Wahl, D. Stern, and P. Nawroth Expression of RAGE in peripheral occlusive vascular disease American Journal of Pathology 146 1995 688 694
72. A. Rojas, and M.A. Morales Nitric oxide, an iceberg in cardiovascular physiology. Far beyond vessel tone control Archives of Medical Research 35 2004 1 11
73. A. Rojas, S. Romay, D. Gonzalez, B. Herrera, R. Delgado, and K. Otero Regulation of endothelial nitric oxide synthase expression by albumin-derived advanced glycosylation end-products Circulation Research 86 2000 50 54
74. N.B. Ruderman, J.R. Williamson, and M. Brownlee Glucose and diabetic vascular disease The FASEB Journal 6 1992 2905 2914
75. B. Schafer, and C. Heizmann The S100 family of EF-hand calcium-binding proteins: functions and pathology Trends in Biochemical Sciences 21 1996 134 140
76. A.M. Schmidt, O. Hori, J. Brett, S.D. Yan, S.D. Wautier, and D. Stern Cellular receptors for AGEs: Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions Arteriosclerosis and Thrombosis 14 1994 1521 1528
77. A.M. Schmidt, O. Hori, J. Chen, J.F. Li, J. Crandall, J. Zhang, R. Cao, S.D. Yan, J. Brett, and D. Stern Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1): a potential mechanism for the accelerated vasculopathy of diabetes The Journal of Clinical Investigation 96 1995 1395 1403
78. A.M. Schmidt, O. Hori, J.X. Chen, J.F. Li, J. Crandall, J. Zhang, R. Cao, S.D. Yan, J. Brett, and D. Stern Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes The Journal of Clinical Investigation 96 1995 1395 1403
79. A.M. Schmidt, M. Vianna, M. Gerlach, J. Brett, J. Ryan, J. Kao, C. Esposito, H. Hegarty, W. Hurley, M. Clauss, F. Wand, Y.-C. Pan, T.C. Tsang, and D. Stern Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface Journal of Biological Chemistry 267 1992 14987 14997
80. A.M. Schmidt, S.D. Yan, and D.M. Stern The dark side of glucose Nature Medicine 1991 1995 1002 1004
81. M.I. Schmidt, B.B. Duncan, A.R. Sharrett, G. Lindberg, P.J. Savage, S. Ofenbacher, M.I. Azambuja, R.P. Tracey, and G. Heiss Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study The Lancet 353 1999 1649 1652
82. K. Sebekova, K. Gazdikova, D. Syrova, P. Blazicek, R. Schinzel, A. Heidland, V. Spustova, and R. Dzurik Effects of ramipril in nondiabetic nephropathy: improved parameters of oxidatives stress and potential modulation of advanced glycation end products Human Hypertension 17 2003 265 270
83. D.R. Sell, and V.M. Monnier Structure elucidation of a senescence cross-link from human extracellular matrix: implications of pentoses in the aging process Journal of Biological Chemistry 264 1989 21597 21602
84. D.R. Sell, A. Lapolla, P. Odetti, J. Forgarty, and V.M. Monnier Pentosidine formation in skin correlates with severity of complication in individuals with long standing IDDM Diabetes 41 1992 1286 1292
85. G. Sengoelge, M. Fodinger, S. Skoupy, I. Ferrara, C. Zangerle, M. Rogy, W.H. Horl, G. Sunder-Plassmann, and J. Menzel Endothelial cell adhesion molecule and PMNL response to inflammatory stimuli and AGE-modified fibronectin Kidney International 54 1998 1637 16351
86. M.J. Sheetz, and G.L. King Molecular understanding of hyperglycemia's adverse effects for diabetic complications Journal American Medical Association 288 2002 2579 2588
87. M. Shoji, T.E. Golde, J. Ghiso, T.T. Cheung, S. Estus, L.M. Shaffer, X.D. Cai, D.M. McKay, R. Tintner, and B. Frangione Production of the Alzheimer amyloid beta protein by normal proteolytic processing Science 258 1992 126 129
88. A. Shostak, and L. Gotloib Increased peritoneal permeability to albumin in streptozotocin diabetic rats Kidney International 49 1996 705 714
89. R. Singh, A. Barden, T. Mori, and L. Beilin Advanced glycation end-products: a review Diabetologia 44 2001 129 146
90. G. Sobala, E.J. Menzel, and H. Sinzinger Calcium antagonists as inhibitors of in vitro low density lipoprotein oxidation and glycation Biochemical Pharmacology 61 2001 373 379
91. T.A. Springer Adhesion receptors of the immune system Nature 346 1990 425 434
92. E.R. Stadtman, and C.N. Oliver Metal catalyzed oxidation of proteins: Physiological consequences Journal of Biological Chemistry 266 1991 2005 2008
93. M.J. Stevens, I. Obrosova, R. Pop-Busui, D.A. Greene, and E.L. Feldman Pathogenesis of diabetic neuropathy D. Porte Jr. R.S. Sherwin A. Baron Ellenberg and Rifkin's diabetes mellitus 2002 McGraw Hill New York, New York 747 770
94. K. Sugaya, T. Fukagawa, K.I. Matsumoto, K. Mita, E.I. Takahashi, A. Ando, H. Inoko, and T. Ikemura Three genes in the human MHC class III region near the junction with class II: gene for RAGE, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-2 Genomics 23 1994 408 419
95. H. Suzuki, Y. Kurihara, M. Takeya, N. Kamada, M. Kataoka, K. Jishage, O. Ueda, H. Sakaguchi, T. Higashi, T. Suzuki, Y. Takashima, Y. Kawabe, O. Cynshi, Y. Wada, M. Honda, H. Kurihara, H. Aburatani, T. Doi, A. Matsumoto, S. Azuma, T. Noda, Y. Toyoda, H. Itakura, Y. Yazaki, S. Horiuchi, K. Takahashi, J.K. Kruijt, J.C. van Berkel, U.P. Steinbrecher, S. Ishibashi, N. Maeda, S. Gordon, and T. Kodama A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection Nature 386 1997 292 296
96. E. Svensjo, F. Cyrino, E. Michoud, D. Ruggiero, E. Bouskela, and N. Wiernsperger Vascular permeability increase as induced by histamine or bradykinin is enhanced by advanced glycation endproducts (AGEs) Journal Diabetes Complications 13 1999 187 190
97. R. Tamarat, J.S. Silvestre, M. Huijberts, J. Benessiano, T.G. Ebrahimian, M. Duriez, M. Wautier, J.L. Wautier, and B. Lévy Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice Proceedings National Academy of Sciences USA 100 2003 8555 8560
98. K.C.B. Tan, W.S. Chow, V.H.G. Ai, C. Metz, R. Bucala, and K.S.L. Lam Advanced glycation end products and endothelial dysfunction in type 2 diabetes Diabetes Care 25 2002 1055 1059
99. P.J. Thornalley Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts Archives Biochemistry and Biophysics 419 2003 31 40
100. C.J. Treutiger, G.E. Mullins, A.S. Johansson, A. Rouhiainen, H.M. Rauvala, H. Erlandsson-Harris, U. Andersson, H. Yang, K.J. Tracey, J. Andersson, and J.E. Palmblad High mobility group 1 B-box mediates activation of human endothelium Journal Internal Medicine 254 2003 375 385
101. P. Ulrich, and A. Cerami Protein glycation, diabetes and aging Recent Progress Hormone Research 56 2001 1 21
102. P.V. Vaitkevicius, M. Lane, H. Spurgeon, D.K. Ingram, G.S. Roth, J.J. Egan, S. Vasan, D.R. Wagle, P. Ulrich, M. Brines, J.P. Wuerth, A. Cerami, and E.G. Lakatta A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys Proceedings National Academy of Sciences USA 98 2001 1171 1175
103. J.R. Vane, and R.M. Botting Formation by the endothelium of prostacyclin, nitric oxide and endothelin Journal Lipid Mediators 6 1993 340 395
104. H. Vlassara, R. Bucala, and L. Stricker Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging Laboratory Investigation 70 1994 138 151
105. H. Vlassara, Y.M. Li, F. Imani, D. Wojciechowicz, Z. Yang, F.T. Liu, and A. Cerami Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins Molecular Medicine 1 1995 634 646
106. J. Waltenberger Impaired collateral vessel development in diabetes: potential cellular mechanisms and therapeutic implications Cardiovascular Research 16 2001 554 560
107. E.N. Wardle Vascular permeability in diabetics and implications for therapy Diabetes Research and Clinical Practice 23 1994 135 139
108. J.L. Wautier, M.P. Wautier, A.M. Schmidt, G.M. Anderson, C. Zoukourian, L. Capron, O. Chappey, S.D. Yan, J. Brett, P.J. Guillausseau, and D. Stern Advanced glycation endproducts (AGEs) on the surface of diabetic red cells bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications Proceedings National Academy of Sciences USA 91 1994 7742 7746
109. J.L. Wautier, C. Zoukourian, O. Chappey, M.P. Wautier, P.J. Guillausseau, R. Cao, O. Hori, D. Stern, and A.M. Schmidt Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy: soluble receptor for advanced glycation endproducts blocks hyperpermeability The Journal Clinical Investigation 97 1996 238 243
110. M.P. Wautier, O. Chappey, S. Corda, D.M. Stern, A.M. Schmidt, and J.M. Wautier Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE American Journal Physiology Endocrinology and Metabolism 280 2001 E685 E694
111. C. Weber Novel mechanistic concepts for the control of leukocyte transmigration: specialization of integrins, chemokines, and junctional molecules Journal of Molecular Medicine 81 2003 4 19
112. J.R. Williamson, K. Chang, R.G. Tilton, C. Prater, J.R. Jeffrey, C. Weigel, W.R. Sherman, D.M. Eades, and C. Kilo Increased vascular permeability in spontaneously diabetic BB/W rats and in rats with mild versus severe streptozocin-induced diabetes Diabetes 36 1987 813 821
113. T. Wisniewski, J. Ghiso, and B. Frangione Biology of beta amyloid in Alzheimer's disease Neurobiology of Disease 4 1997 313 328
114. B. Xu, R. Chibber, D. Ruggerio, E. Kohner, J. Ritter, and A. Ferro Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products The FASEB Journal 17 2003 1289 1291
115. S. Yamagishi, H. Fujimori, H. Yonekura, Y. Yamamoto, and H. Yamamoto Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells Diabetologia 41 1998 1435 1441
116. S. Yamagishi, C.C. Hsu, M. Taniguchi, S. Harada, Y. Yamamoto, K. Ohsawa, K. Kobayashi, and H. Yamamoto Receptor-mediated toxicity to pericytes of advanced glycosylation end products: a possible mechanism of pericyte loss in diabetic microangiopathy Biochemical Biophysical. Research Communications 213 1995 681 687
117. S. Yamagishi, H. Yonekura, Y. Yamamoto, K. Katsuno, F. Sato, I. Mita, H. Ooka, N. Satozawa, T. Kawakami, M. Nomura, and Y. Yamamoto Advanced glycation end products-driven angiogenesis in vitro. Induction of the growth and tube formation of human microvascular endothelial cells through autocrine vascular endothelial growth factor Journal Biological Chemistry 272 1997 8723 8730
118. S.D. Yan, A.M. Schmidt, G.M. Anderson, J. Zhang, J. Brett, Y.S. Zou, D. Pinsky, and D. Stern Enhanced cellular oxidant stress by the interaction of AGEs with their receptors/binding proteins Journal Biological Chemistry 269 1994 9889 9897
119. Z. Yang, Z. Makita, Y. Horii, S. Brunelle, A. Cerami, P. Sehajpal, M. Suthanthiran, and H. Vlassara Two novel rat liver membrane proteins that bind advanced glycosylation endproducts: relationship to macrophage receptor for glucose-modified proteins Journal Experimental Medicine 174 1991 515 524
120. V.A. Yaylayan, and A. Huyghues-Despointes Chemistry of Amadori rearrangement products: analysis, synthesis, kinetics, reactions, and spectroscopic properties Critical Reviews Food Science and Nutrition 34 1994 321 369
121. D.V. Zyzak, J.M. Richardson, S.R. Thorpe, and J.W. Baynes Formation of reactive intermediates from Amadori compounds under physiological conditions Archives of Biochemistry and Biophysics 316 1995 547 554