Mapping the melatonin receptor. 7. Subtype selective ligands based on β-substituted N-acyl-5-methoxytryptamines and β-Substituted N-acyl-5-methoxy-1-methyltryptamines

Journal of Medicinal Chemistry

Volumn 49, Issue 12, 2006, Pages 3509-3519

  Tsotinis, Andrew ^a   Vlachou, Margarita ^a   Papahatjis, Demetris P ^b   Calogeropoulou, Theodora ^b   Nikas, Spyros P ^b   Garratt, Peter J ^c   Piccio, Vincent ^c   Vonhoff, Stefan ^c   Davidson, Kathryn ^d   Teh, Muy Teck ^e   Sugden, David ^d  

^a UNIVERSITY OF ATHENS   (Greece)

^b INSTITUTE OF BIOLOGY   (Greece)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHOXYTRYPTAMINE; BETA METHYLMELATONIN; BETA,BETA DIMETHYLMELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; MELATONIN DERIVATIVE; MELATONIN RECEPTOR; N ACYL 5 METHOXY 1 METHYLTRYPTAMINE DERIVATIVE; N ACYL 5 METHOXYTRYPTAMINE DERIVATIVE; N BUTANOYL 5 METHOXY 1 METHYL BETA,BETA TETRAMETHYLENETRYPTAMINE; N BUTANOYL 5 METHOXY 1 METHYL BETA,BETA TRIMETHYLENETRYPTAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING ASSAY; BINDING SITE; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; EMBRYO; HUMAN; HUMAN CELL; MELANOPHORE; MOLECULAR CLONING; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; XENOPUS LAEVIS;

ANIMALS; BINDING SITES; CELL LINE; HUMANS; LIGANDS; MELANOPHORES; MELATONIN; MICE; MOLECULAR CONFORMATION; NIH 3T3 CELLS; PIGMENTS, BIOLOGICAL; RADIOLIGAND ASSAY; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTAMINES; XENOPUS LAEVIS;

EID: 33745121849     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0512544     Document Type: Article

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