Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1- a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles

Journal of Medicinal Chemistry

Volumn 43, Issue 6, 2000, Pages 1050-1061

  Faust, Rüdiger ^a   Garratt, Peter J ^a   Jones, Rob ^a   Yeh, Li Kuan ^a   Tsotinis, Andrew ^b   Panoussopoulou, Maria ^b   Calogeropoulou, Theodora ^c   Teh, Muy Teck ^d   Sugden, David ^d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ATHENS   (Greece)

^c INSTITUTE OF BIOLOGY   (Greece)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIHYDROINDOLO[2,1 A]ISOQUINOLINE; 6,7 DIHYDRO 5H BENZO[C]AZEPINO[2,1 A]INDOLE; 6H ISOINDOLO[2,1 A]INDOLE; INDOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; MELATONIN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CLONAL ANERGY; CONFORMATIONAL TRANSITION; DRUG SYNTHESIS; LIGAND BINDING; MELANOPHORE; MOLECULAR CLONING; NONHUMAN; RECEPTOR BINDING; XENOPUS LAEVIS;

3T3 CELLS; ANIMALS; BINDING, COMPETITIVE; CYCLIC AMP; HUMANS; INDOLES; MELATONIN; MICE; PIGMENTS, BIOLOGICAL; RADIOLIGAND ASSAY; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0034704888     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980684+     Document Type: Article

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