Mapping the melatonin receptor. 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles

Journal of Medicinal Chemistry

Volumn 41, Issue 4, 1998, Pages 451-467

  Davies, David J ^a   Garratt, Peter J ^a   Tocher, Derek A ^a   Vonhoff, Stefan ^a   Davies, John ^b   Teh, Muy Teck ^c   Sugden, David ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Sandoz Institute for Medical Research   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 METHOXYTETRAHYDROCARBAZOLE DERIVATIVE; CARBAZOLE DERIVATIVE; INDOLE DERIVATIVE; MELATONIN DERIVATIVE; MELATONIN RECEPTOR; N ACYL 1 (AMINOMETHYL) 7 METHOXY 4 METHYLTETRAHYDROCYCLOPENT[B]INDOLE DERIVATIVE; N ACYL 10 (AMINOMETHYL) 2 METHOXY 5 METHYLHEXAHYDROCYCLOHEPT[B]INDOLE DERIVATIVE; N ACYL 3 AMINO 6 METHOXYTETRAHYDROCARBAZOLE DERIVATIVE; N ACYL 4 (AMINOMETHYL) 6 METHOXY 9 METHYLTETRAHYDROCARBAZOLE DERIVATIVE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN MEMBRANE; CHICKEN; CONTROLLED STUDY; LIGAND BINDING; MELANOPHORE; NONHUMAN; RECEPTOR BINDING; XENOPUS LAEVIS;

ANIMALS; BINDING, COMPETITIVE; BRAIN; CARBAZOLES; CELL MEMBRANE; CHICKENS; CRYSTALLOGRAPHY, X-RAY; INDICATORS AND REAGENTS; INDOLES; MELANOPHORES; MELATONIN; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0032510073     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970246n     Document Type: Article

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