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Volumn 40, Issue 5, 1997, Pages 739-748

Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: A comparative molecular field analysis study

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN; MELATONIN RECEPTOR;

EID: 0031052115     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960680+     Document Type: Article
Times cited : (58)

References (39)
  • 1
    • 0025758136 scopus 로고
    • Pineal Melatonin: Cell Biology of its Synthesis and its Physiological Interactions
    • Reiter, R. J. Pineal Melatonin: Cell Biology of its Synthesis and its Physiological Interactions. Endocr. Rev. 1991, 12, 151-180.
    • (1991) Endocr. Rev. , vol.12 , pp. 151-180
    • Reiter, R.J.1
  • 2
    • 0003069086 scopus 로고
    • Melatonin and the Human Circadian System
    • Miles, A., Philbrick, D. R. S., Thompson, C., Eds.; Oxford University Press: Oxford
    • Arendt, J. Melatonin and the Human Circadian System. In Melatonin, clinical perspectives; Miles, A., Philbrick, D. R. S., Thompson, C., Eds.; Oxford University Press: Oxford, 1988; pp 43-61.
    • (1988) Melatonin, Clinical Perspectives , pp. 43-61
    • Arendt, J.1
  • 3
    • 0026672613 scopus 로고
    • Melatonin - The Hormone of Darkness
    • Utiger, R. D. Melatonin - The Hormone of Darkness. N. Engl. J. Med. 1992, 327, 1377-1379.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1377-1379
    • Utiger, R.D.1
  • 4
    • 0002604968 scopus 로고
    • Neuroendocrinology of Melatonin
    • Miles, A., Philbrick, D. R. S.; Thompson, C., Eds.; Oxford University Press: Oxford
    • Reiter, R. J. Neuroendocrinology of Melatonin. In Melatonin, clinical perspectives; Miles, A., Philbrick, D. R. S.; Thompson, C., Eds.; Oxford University Press: Oxford, 1988; pp 1-42.
    • (1988) Melatonin, Clinical Perspectives , pp. 1-42
    • Reiter, R.J.1
  • 5
    • 0027210003 scopus 로고
    • The Melatonin Rhythm, both a Clock and a Calendar
    • Reiter, R. J. The Melatonin Rhythm, both a Clock and a Calendar, Experientia 1993, 49, 654-664.
    • (1993) Experientia , vol.49 , pp. 654-664
    • Reiter, R.J.1
  • 6
    • 0026099812 scopus 로고
    • Correction of non-24 Hour/ Sleep/Wake Cycle by Melatonin in a Blind Retarded Boy
    • Palm L.; Blennow, G.; Wetterberg, L. Correction of non-24 Hour/ Sleep/Wake Cycle by Melatonin in a Blind Retarded Boy. Annal. Neurol. 1991, 29, 336-339.
    • (1991) Annal. Neurol. , vol.29 , pp. 336-339
    • Palm, L.1    Blennow, G.2    Wetterberg, L.3
  • 9
    • 0027196665 scopus 로고
    • The Immunoneuroendocrine Role of Melatonin
    • Maestroni, G. J. M. The Immunoneuroendocrine Role of Melatonin. J. Pineal Res. 1993, 14, 1-10.
    • (1993) J. Pineal Res. , vol.14 , pp. 1-10
    • Maestroni, G.J.M.1
  • 10
    • 0027258154 scopus 로고
    • Melatonin, Hydroxy Radical-Mediated Oxidative Damage, and Aging: A Hypothesis
    • Poeggeler, B.; Reiter, R. J.; Tan, D.-X.; Chen, L.-D.; Manchester, L. C. Melatonin, Hydroxy Radical-Mediated Oxidative Damage, and Aging: a Hypothesis. J. Pineal Res. 1993, 14, 151-158.
    • (1993) J. Pineal Res. , vol.14 , pp. 151-158
    • Poeggeler, B.1    Reiter, R.J.2    Tan, D.-X.3    Chen, L.-D.4    Manchester, L.C.5
  • 11
    • 0024472685 scopus 로고
    • Guanine Nucleotides Regulate the Affinity of Melatonin Receptors on the Ovine Pars Tuberalis
    • Morgan, P. J.; Lawson, W.; Davidson, G.; Howell, H. E. Guanine Nucleotides Regulate the Affinity of Melatonin Receptors on the Ovine Pars Tuberalis. Neuroendocrinology 1989, 50, 359-362.
    • (1989) Neuroendocrinology , vol.50 , pp. 359-362
    • Morgan, P.J.1    Lawson, W.2    Davidson, G.3    Howell, H.E.4
  • 12
    • 0028120836 scopus 로고
    • Melatonin: Binding Site Characteristics and Biochemical and Cellular Responses
    • Sugden, D. Melatonin: Binding Site Characteristics and Biochemical and Cellular Responses. Neurochem. Int. 1994, 24, 147-157.
    • (1994) Neurochem. Int. , vol.24 , pp. 147-157
    • Sugden, D.1
  • 13
    • 0028306136 scopus 로고
    • Expression Cloning of a High-Affinity Melatonin Receptor from Xenopus Dermal Melanophores
    • Ebisawa, T.; Karne, S.; Lerner, M. R.; Reppert, S. M. Expression Cloning of a High-Affinity Melatonin Receptor from Xenopus Dermal Melanophores. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 6133-6137.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 6133-6137
    • Ebisawa, T.1    Karne, S.2    Lerner, M.R.3    Reppert, S.M.4
  • 14
    • 0028018966 scopus 로고
    • Cloning and Characterization of a Mammalian Melatonin Receptor that Mediates Reproductive and Circadian Responses
    • (a) Reppert, S. M.; Weaver, D. R.; Ebisawa, T. Cloning and Characterization of a Mammalian Melatonin Receptor that Mediates Reproductive and Circadian Responses. Neuron 1994, 13, 1177-1185.
    • (1994) Neuron , vol.13 , pp. 1177-1185
    • Reppert, S.M.1    Weaver, D.R.2    Ebisawa, T.3
  • 16
    • 0028868913 scopus 로고
    • Melatonin Receptors are for the Birds: Molecular Analysis of two Receptor Subtypes Differentially Expressed in Chick Brain
    • (c) Reppert, S. M.; Weaver, D. R.; Cassone, V. M.; Godson, C. D; Kolakowski, L. F., Jr. Melatonin Receptors are for the Birds: Molecular Analysis of two Receptor Subtypes Differentially Expressed in Chick Brain. Neuron 1995, 15, 1003-1015.
    • (1995) Neuron , vol.15 , pp. 1003-1015
    • Reppert, S.M.1    Weaver, D.R.2    Cassone, V.M.3    Godson, C.D.4    Kolakowski Jr., L.F.5
  • 17
    • 0016695162 scopus 로고
    • Structure Activity-Relationships of Melatonin and Related Indoleamines
    • (a) Heward, C. B.; Hadley, M. E. Structure Activity-Relationships of Melatonin and Related Indoleamines. Life Sci. 1975, 17, 1167-1177.
    • (1975) Life Sci. , vol.17 , pp. 1167-1177
    • Heward, C.B.1    Hadley, M.E.2
  • 18
    • 0027716547 scopus 로고
    • 2-Substituted 5-methoxy N-acyltryptamines: Synthesis, Binding Affinity for the Melatonin Receptor, and Evaluation of the Biological Activity
    • (b) Spadoni, G.; Stankov, B.; Duranti, A.; Biella, G.; Lucini, V.; Salvatori, A.; Fraschini, F. 2-Substituted 5-methoxy N-acyltryptamines: Synthesis, Binding Affinity for the Melatonin Receptor, and Evaluation of the Biological Activity. J. Med. Chem. 1993, 36, 4069-4074.
    • (1993) J. Med. Chem. , vol.36 , pp. 4069-4074
    • Spadoni, G.1    Stankov, B.2    Duranti, A.3    Biella, G.4    Lucini, V.5    Salvatori, A.6    Fraschini, F.7
  • 19
    • 0028310827 scopus 로고
    • Mapping the Melatonin Receptor. 1. The 5-Methoxyl Group of Melatonin is not an Essential Requirement for Biological Activity
    • (c) Garratt, P. J.; Jones, R.; Rowe, S. J.; Sugden, D. Mapping the Melatonin Receptor. 1. The 5-Methoxyl Group of Melatonin is not an Essential Requirement for Biological Activity. Bioorg. Med. Chem. Lett. 1994, 4, 1555-1558.
    • (1994) Bioorg. Med. Chem. Lett. , vol.4 , pp. 1555-1558
    • Garratt, P.J.1    Jones, R.2    Rowe, S.J.3    Sugden, D.4
  • 20
    • 0028970287 scopus 로고
    • Mapping the Melatonin Receptor. 3. Design and Synthesis of Melatonin Agonists and Antagonists Derived from 2-Phenyltryptamines
    • (d) Garratt, P. J.; Jones R.; Tocher, D. A.; Sugden, D. Mapping the Melatonin Receptor. 3. Design and Synthesis of Melatonin Agonists and Antagonists Derived from 2-Phenyltryptamines. J. Med. Chem. 1995, 38, 1132-1139.
    • (1995) J. Med. Chem. , vol.38 , pp. 1132-1139
    • Garratt, P.J.1    Jones, R.2    Tocher, D.A.3    Sugden, D.4
  • 21
    • 0028309734 scopus 로고
    • Mapping the Melatonin Receptor. 2. Synthesis and Biological Activity of Indole Derived Melatonin Analogues with Restricted Conformations of the C-3 Amidoethane Side Chain
    • (e) Garrat, P. J.; Vonhoff, S.; Rowe, S. J.; Sugden, D. Mapping the Melatonin Receptor. 2. Synthesis and Biological Activity of Indole Derived Melatonin Analogues with Restricted Conformations of the C-3 Amidoethane Side Chain. Bioorg. Med. Chem. Lett. 1994, 4, 1559-1564.
    • (1994) Bioorg. Med. Chem. Lett. , vol.4 , pp. 1559-1564
    • Garrat, P.J.1    Vonhoff, S.2    Rowe, S.J.3    Sugden, D.4
  • 22
    • 0012084152 scopus 로고
    • New Molecules Active at the Melatonin Receptor Level
    • Fraschini, F., Reiter, R. J., Stankov, B., Eds.; Plenum Press: New York and London
    • (f) Fraschini, F.; Stankov, B. New Molecules Active at the Melatonin Receptor Level. In The pineal gland and its hormones; Fraschini, F., Reiter, R. J., Stankov, B., Eds.; Plenum Press: New York and London, 1995; pp 131-138.
    • (1995) The Pineal Gland and Its Hormones , pp. 131-138
    • Fraschini, F.1    Stankov, B.2
  • 26
    • 0027489431 scopus 로고
    • Conformational Properties of Melatonin and two Conformationally Restricted Agonists: A Molecular Mechanics and NMR Spectroscopy Study
    • Jansen, J. M.; Karlén, A.; Grol, C. J.; Hacksell, U. Conformational Properties of Melatonin and two Conformationally Restricted Agonists: a Molecular Mechanics and NMR Spectroscopy Study. Drug Des. Discovery 1993, 10, 115-133.
    • (1993) Drug Des. Discovery , vol.10 , pp. 115-133
    • Jansen, J.M.1    Karlén, A.2    Grol, C.J.3    Hacksell, U.4
  • 27
    • 0027482462 scopus 로고
    • 2-Amido-8-methoxytetralins: A Series of Nonindolic Melatonin-like Agents
    • Copinga, S.; Tepper, P. G.; Grol, C. J.; Horn, A. S.; Dubocovich, M. L. 2-Amido-8-methoxytetralins: A Series of Nonindolic Melatonin-like Agents. J. Med. Chem. 1993, 36, 2891-2898.
    • (1993) J. Med. Chem. , vol.36 , pp. 2891-2898
    • Copinga, S.1    Tepper, P.G.2    Grol, C.J.3    Horn, A.S.4    Dubocovich, M.L.5
  • 28
    • 0029616447 scopus 로고
    • Radioligand Binding Affinity and Biological Activity of the Enantiomers of a Chiral Melatonin Analogue
    • Sudgen, D.; Davies, D. J.; Garratt, P. J.; Jones, R.; Vonhoff, S. Radioligand Binding Affinity and Biological Activity of the Enantiomers of a Chiral Melatonin Analogue. Eur. J. Pharmacol. 1995, 287, 239-243.
    • (1995) Eur. J. Pharmacol. , vol.287 , pp. 239-243
    • Sudgen, D.1    Davies, D.J.2    Garratt, P.J.3    Jones, R.4    Vonhoff, S.5
  • 29
    • 15144353048 scopus 로고    scopus 로고
    • Langlois M.; Mathé-Allainmat, M.; Renard, P.; Delagrange, Ph.; Guadiola-LeMaitre, B. French Patent 95 04503
    • Langlois M.; Mathé-Allainmat, M.; Renard, P.; Delagrange, Ph.; Guadiola-LeMaitre, B. French Patent 95 04503.
  • 31
    • 0028909154 scopus 로고
    • Structural Requirements at the Melatonin Receptor
    • Sugden, D.; Chong, N. W. S.; Lewis, D. F. V. Structural Requirements at the Melatonin Receptor. Br. J. Pharmacol. 1995, 114, 618-623.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 618-623
    • Sugden, D.1    Chong, N.W.S.2    Lewis, D.F.V.3
  • 32
    • 0030598632 scopus 로고    scopus 로고
    • A Rhodopsin-based Model for Melatonin Recognition at its G-Protein Coupled Receptor
    • Navajas, C.; Kokkola, T.; Poso, A.; Honka, N.; Gynther, J.; Laitinen, J. T. A Rhodopsin-based Model for Melatonin Recognition at its G-Protein Coupled Receptor. Eur. J. Pharmacol. 1996, 304, 173-183.
    • (1996) Eur. J. Pharmacol. , vol.304 , pp. 173-183
    • Navajas, C.1    Kokkola, T.2    Poso, A.3    Honka, N.4    Gynther, J.5    Laitinen, J.T.6
  • 33
    • 0030220790 scopus 로고    scopus 로고
    • The High Affinity Melatonin Binding Site Probed with Conformationally Restricted Ligands-II. Homology Modeling of the Receptor
    • Grol, C. J.; Jansen, J. M. The High Affinity Melatonin Binding Site Probed with Conformationally Restricted Ligands-II. Homology Modeling of the Receptor. Bioorg. Med. Chem. 1996, 4, 1333-1339.
    • (1996) Bioorg. Med. Chem. , vol.4 , pp. 1333-1339
    • Grol, C.J.1    Jansen, J.M.2
  • 34
    • 0023751431 scopus 로고
    • Comparative molecular field analysis (CoMFA). 1. Effect of Shape on Binding of Steroids to Carrier Proteins
    • Cramer, R. D. III; Patterson, D. E.; Bunce, J. D. Comparative molecular field analysis (CoMFA). 1. Effect of Shape on Binding of Steroids to Carrier Proteins. J. Am. Chem. Soc. 1988, 110, 5959-5967.
    • (1988) J. Am. Chem. Soc. , vol.110 , pp. 5959-5967
    • Cramer III, R.D.1    Patterson, D.E.2    Bunce, J.D.3
  • 38
    • 0027762073 scopus 로고
    • Three Dimensional QSAR of Human Immunodeficiency Virus (I) Protease Inhibitors. 1. A CoMFA Study Employing Experimentally Determined Alignment Rules
    • Waller, C. L.; Oprea, T. I.; Giolitti, A.; Marshall, G. R. Three Dimensional QSAR of Human Immunodeficiency Virus (I) Protease Inhibitors. 1. A CoMFA Study Employing Experimentally Determined Alignment Rules. J. Med. Chem 1993, 36, 4152-4160.
    • (1993) J. Med. Chem , vol.36 , pp. 4152-4160
    • Waller, C.L.1    Oprea, T.I.2    Giolitti, A.3    Marshall, G.R.4
  • 39
    • 0030201178 scopus 로고    scopus 로고
    • The High Affinity Melatonin Binding Site Probed with Conformationally Restricted Ligands-I. Pharmacophore and Minireceptor Models
    • Jansen, J. M.; Copinga, S.; Gruppen, G.; Molinari, E. J.; Dubocovich, M. L.; Grol, C. J. The High Affinity Melatonin Binding Site Probed with Conformationally Restricted Ligands-I. Pharmacophore and Minireceptor Models. Bioorg Med. Chem. 1996, 4, 1332.
    • (1996) Bioorg Med. Chem. , vol.4 , pp. 1332
    • Jansen, J.M.1    Copinga, S.2    Gruppen, G.3    Molinari, E.J.4    Dubocovich, M.L.5    Grol, C.J.6


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