Synthesis of N1-phenethyl substituted indole derivatives as new melatoninergic agonists and antagonists

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 1, 2002, Pages 31-39

  Tsotinis, Andrew ^a   Vlachou, Margarita ^a   Eleutheriades, Andreas ^a   Prinea, Effie ^a   Ebreo, Darren ^b   The, Muy Teck ^b   Sugden, David ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Melatonin agonist antagonist; N1 substituted indole; Synthesis; Xenopus laevis melanophore model

Indexed keywords

2 [5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL] 2 METHYLPROPIONAMINE; 2 [5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL] 2 METHYLPROPIONITRILE; INDOLE DERIVATIVE; LIGAND; MELATONIN; N [2 [5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL] 2 METHYLPROPYL]ACETAMIDE; N [2 [5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL] 2 METHYLPROPYL]BUTYRAMIDE; N [2 [5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL] 2 METHYLPROPYL]CYCLOBUTANECARBOXAMIDE; N [2 [5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL] 2 METHYLPROPYL]CYCLOPROPANECARBOXAMIDE; N [2 [5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL] 2 METHYLPROPYL]PROPIONAMIDE; UNCLASSIFIED DRUG; ACETAMIDE DERIVATIVE; CELL RECEPTOR; CELL SURFACE RECEPTOR; MELATONIN RECEPTOR; N (2 (1 (2 PHENETHYL) 1H INDOL 3 YL)ETHYL)ACETAMIDE; N (2 (5 METHOXY 1 (2 PHENETHYL) 1H INDOL 3 YL)ETHYL)ACETAMIDE; N-(2-(1-(2-PHENETHYL)-1H-INDOL-3-YL)ETHYL)ACETAMIDE; N-(2-(5-METHOXY-1-(2-PHENETHYL)-1H-INDOL-3-YL)ETHYL)ACETAMIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; MELANOPHORE; NONHUMAN; XENOPUS LAEVIS; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACETAMIDES; ANIMALS; INDOLES; LIGANDS; MELANOPHORES; MELATONIN; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0036369308     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.31     Document Type: Article

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