Synthesis and biological activity of conformationally restricted tricyclic analogs of the hormone melatonin

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 10, 1996, Pages 1071-1076

  Leclerc, V ^a   Depreux, P ^a   Lesieur, D ^a   Caignard, D H ^b   Renard, P ^b   Delagrange, P ^b   Guardiola Lemaitre, B ^b   Morgan, P ^c  

^a IFR114   (France)

^b ADIR   (France)

^c ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; DIOXANE; FORSKOLIN; FURAN DERIVATIVE; HORMONE ANALOG; MELATONIN; MELATONIN RECEPTOR; NAPHTHALENE DERIVATIVE; PYRAN DERIVATIVE; RECEPTOR SUBTYPE; TETRALIN DERIVATIVE;

AGONIST; ANIMAL TISSUE; ARTICLE; DRUG CONFORMATION; DRUG SYNTHESIS; HORMONE RECEPTOR INTERACTION; HYPOPHYSIS PARS TUBERALIS; MOLECULAR RECOGNITION; NONHUMAN; PHOTOPERIODICITY; RECEPTOR AFFINITY; SHEEP; STRUCTURE ACTIVITY RELATION;

ANIMALIA; OVIS ARIES;

EID: 0030000102     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00175-8     Document Type: Article

References (23)

1. Lerner A.B., Case D.J., Takahashi Y., Lee T.H., Mori W., J. Am. Chem. Soc., 1959, 81, 6084-6085.
2. Pevet P., Masson-Pevet M., Hermes M.L.H.J., Buijs R.M., Cangulhem B., Colloque Inserm, Paris : John Libbey; 1989, 43-51.
3. Arendt J., Boberly A.A., Franey C., Wright J., Neurosci. Lett., 1984, 45, 317-321.
4. Guardiola-Lemaître B., Adv. Pineal Res., 1991, 351-353.
5. Claustrat B., Le Bards D., Brun J., Thivolle P., Mallo C., Arendt J., Chazot G., Adv. Pineal Res., 1989, 305-310.
6. Yous S., Andrieux J., Howell H.E., Morgan P.J., Renard P., Pfeiffer B., Lesieur D., Guardiola-Lemaitre B., J. Med. Chem., 1992, 35, 1484-1485.
7. Depreux P., Lesieur D., Ait Mansour H., Morgan P., Howell H.E., Renard P., Caignard D.H., Pfeiffer B., Delagrange P., Guardiola B., Yous S., Demarque A., Adam G., Andrieux J., J. Med. Chem., 1994, 37, 3231-3239.
8. Unpublished results.
9. Spadoni G., Stankov B., Duranti A., Biella G., Lucini V., Salvatori A., Fraschini F., J. Med. Chem., 1993, 36, 4069-4074.
10. Garratt P.J., Vonhoff S., Rowe S.J., Sugden D., Bioorg. Med. Chem. Lett., 1994, 4, 1559-1564.
11. Garratt P.J., Jones R., Rowe S.J., Sugden D., Bioorg. Med. Chem. Lett., 1994, 4, 1555-1558.
12. Sugden D., Chong N.W.S., Lewis D.F.V., Br. J. Pharmacol., 1995, 114, 618-623.
13. Newman M.S., Hung W.M., J. Org. Chem., 1973, 38, 4073-4074.
14. Chaikin S.W., Brown W.G., J. Am. Chem. Soc., 1949, 71, 122-125.
15. Kawase Y., Nakamoto S., Bull. Chem. Soc. Jap., 1962, 35, 1624-1625.
16. Svanholm U., Parker V.D., J. Chem. Soc. Perkin Trans. II, 1974, 2, 169-173.
17. Rao U., Balasubramanian K.K., Tetrahedron Lett., 1983, 24, 5023-5024.
18. Weitkamp A.W., Advances in catalysis and related subjects, 1968, 1-110.
19. Garratt P.J., Doecke C.W., Weber J.C., Paquette L.A., J. Org. Chem., 1986, 51, 449-452.
20. Kawasaki I., Matsuda K., Kaneko T., Bull. Chem. Soc. Jap., 1971, 44, 1986-1987.
21. Wadsworth W.S.Jr., Emmons W.D., J. Am. Chem. Soc., 1961, 83, 1733-1738.
22. Morgan P.J., Lawson M., Davidson G., Howell H.E., J. Mol. Endocrinol., 1989, 5, 3-8.
23. Morgan P.J., Williams L.M., Davidson G., Laxson W., Howell H.E., J. Neuroendocrinol., 1989, 1, 1-4.