Binding affinity and biological activity of oxygen and sulfur isosteres at melatonin receptors as a function of their hydrogen bonding capability

Bioorganic Chemistry

Volumn 32, Issue 1, 2004, Pages 1-12

  Davies, David J ^a   Faust, Rüdiger ^a   Garratt, Peter J ^a   Marivingt Mounir, Cécile ^a   Kathryn Davidson, ^b   Teh, Muy Teck ^b,c   Sugden, David ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c Clinical Sciences Research Centre   (United Kingdom)

Author keywords

Hydrogen bonds; Lawesson's reagent; Melanophores; Melatonin

Indexed keywords

3 (2 NITROVINYL) 5 METHYLTHIOINDOLE; ACETAMIDE DERIVATIVE; ACETIC ACID DERIVATIVE; AMIDE; HYDROGEN; INDOLE DERIVATIVE; MELATONIN; MELATONIN DERIVATIVE; MELATONIN RECEPTOR; N ACETYL 5 ETHOXYTRYPTAMINE; N [2 (5 ETHOXYINDOL 3 YL)ETHYL]THIOACETAMIDE; N [2 (5 ETHYLTHIOINDOL 3 YL)ETHYL]ACETAMIDE; N [2 (5 ETHYLTHIOINDOL 3 YL)ETHYL]THIOACETAMIDE; N [2 (5 METHOXYINDOL 3 YL)ETHYL]THIOACETAMIDE; N [2 (5 METHYLTHIOINDOL 3 YL)ETHYL]ACETAMIDE; OXYGEN; SULFUR DERIVATIVE; TRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

AMPHIBIA; ANIMAL CELL; ARTICLE; ASSAY; ATOMIC PARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; HYDROGEN BOND; MELANOPHORE; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

AMPHIBIA; MELANOPHORA;

EID: 0348231818     PISSN: 00452068     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bioorg.2003.09.004     Document Type: Article

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