메뉴 건너뛰기




Volumn 23, Issue 1, 2006, Pages 37-49

Impact of growth factors in the regulation of apoptosis in low-risk myelodysplastic syndromes

Author keywords

Apoptosis; Erythropoietin; Fas; G CSF; Mitochondria; Myelodysplastic syndrome

Indexed keywords

FERRITIN; HEMOPOIETIC GROWTH FACTOR; PROTEIN BCL 2; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

EID: 33646858141     PISSN: 13570560     EISSN: None     Source Type: Journal    
DOI: 10.1385/MO:23:1:37     Document Type: Review
Times cited : (5)

References (136)
  • 1
    • 0030682515 scopus 로고    scopus 로고
    • Erythroid response to treatment with G-CSF plus erythropoietin for the anaemia of patients with myelodysplastic syndromes: Proposal for a predictive model
    • Hellstrom-Lindberg E, et al. Erythroid response to treatment with G-CSF plus erythropoietin for the anaemia of patients with myelodysplastic syndromes: proposal for a predictive model. Br J Haematol 1997;99(2):344-351.
    • (1997) Br J Haematol , vol.99 , Issue.2 , pp. 344-351
    • Hellstrom-Lindberg, E.1
  • 2
    • 2642686614 scopus 로고    scopus 로고
    • Treatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor plus erythropoietin: Results from a randomized phase II study and long-term follow-up of 71 patients
    • Hellstrom-Lindberg E, et al. Treatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor plus erythropoietin: results from a randomized phase II study and long-term follow-up of 71 patients. Blood 1998;92(1):68-75.
    • (1998) Blood , vol.92 , Issue.1 , pp. 68-75
    • Hellstrom-Lindberg, E.1
  • 3
    • 0036180269 scopus 로고    scopus 로고
    • Increased incidence of mitochondrial cytochrome c-oxidase gene mutations in patients with myelodysplastic syndromes
    • Reddy PL, et al. Increased incidence of mitochondrial cytochrome c-oxidase gene mutations in patients with myelodysplastic syndromes. Br J Haematol 2002;116(3): 564-575.
    • (2002) Br J Haematol , vol.116 , Issue.3 , pp. 564-575
    • Reddy, P.L.1
  • 4
    • 0031906395 scopus 로고    scopus 로고
    • Pathogenesis, etiology and epidemiology of myelodysplastic syndromes
    • Aul C, Bowen DT, Yoshida Y. Pathogenesis, etiology and epidemiology of myelodysplastic syndromes. Haematologica 1998;83(1):71-86.
    • (1998) Haematologica , vol.83 , Issue.1 , pp. 71-86
    • Aul, C.1    Bowen, D.T.2    Yoshida, Y.3
  • 5
    • 0031981671 scopus 로고    scopus 로고
    • Increasing incidence of myelodysplastic syndromes: Real or fictitious?
    • Aul C, Germing U, Gattermann N, Minning H. Increasing incidence of myelodysplastic syndromes: real or fictitious? Leuk Res 1998;22(1):93-100.
    • (1998) Leuk Res , vol.22 , Issue.1 , pp. 93-100
    • Aul, C.1    Germing, U.2    Gattermann, N.3    Minning, H.4
  • 6
    • 0026688084 scopus 로고
    • Age-related incidence and other epidemiological aspects of myelodysplastic syndromes
    • Aul C, Gattermann N, Schneider W. Age-related incidence and other epidemiological aspects of myelodysplastic syndromes. Br J Haematol 1992;82(2):358-367.
    • (1992) Br J Haematol , vol.82 , Issue.2 , pp. 358-367
    • Aul, C.1    Gattermann, N.2    Schneider, W.3
  • 8
    • 0030016365 scopus 로고    scopus 로고
    • Epidemiological characteristics of myelodysplastic syndrome in a well-defined French population
    • Maynadie M, et al. Epidemiological characteristics of myelodysplastic syndrome in a well-defined French population. Br J Cancer 1996;74(2):288-290.
    • (1996) Br J Cancer , vol.74 , Issue.2 , pp. 288-290
    • Maynadie, M.1
  • 9
    • 0035375406 scopus 로고    scopus 로고
    • Epidemiological features of myelodysplastic syndromes: Results from regional cancer surveys and hospital-based statistics
    • Aul C, Giagounidis A, Germing U. Epidemiological features of myelodysplastic syndromes: results from regional cancer surveys and hospital-based statistics. Int J Hematol 2001;73(4):405-410.
    • (2001) Int J Hematol , vol.73 , Issue.4 , pp. 405-410
    • Aul, C.1    Giagounidis, A.2    Germing, U.3
  • 10
    • 0025871416 scopus 로고
    • Increasing prevalence of the myelodysplastic syndrome. An international Delphi study
    • Reizenstein P, Dabrowski L. Increasing prevalence of the myelodysplastic syndrome. An international Delphi study. Anticancer Res 1991;11(3):1069-1070.
    • (1991) Anticancer Res , vol.11 , Issue.3 , pp. 1069-1070
    • Reizenstein, P.1    Dabrowski, L.2
  • 12
    • 33646856085 scopus 로고    scopus 로고
    • No evidence of increasing incidence of MDS
    • Germing U, et al. No evidence of increasing incidence of MDS. Leuk Res 2003;27 (suppl 1):S2.
    • (2003) Leuk Res , vol.27 , Issue.1 SUPPL.
    • Germing, U.1
  • 13
    • 0019952276 scopus 로고
    • Proposals for the classification of the myelodysplastic syndromes
    • Bennett JM, et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982;51(2): 189-199.
    • (1982) Br J Haematol , vol.51 , Issue.2 , pp. 189-199
    • Bennett, J.M.1
  • 15
    • 0034305979 scopus 로고    scopus 로고
    • Problematic WHO reclassification of myelodysplastic syndromes
    • Members of the International MDS Study Group
    • Greenberg P, et al. Problematic WHO reclassification of myelodysplastic syndromes. Members of the International MDS Study Group. J Clin Oncol 2000;18(19):3447-3452.
    • (2000) J Clin Oncol , vol.18 , Issue.19 , pp. 3447-3452
    • Greenberg, P.1
  • 16
    • 0035892129 scopus 로고    scopus 로고
    • Myelodysplastic syndromes, from French-American-British to World Health Organization: Comparison of classifications on 431 unselected patients from a single institution
    • Nosslinger T, et al. Myelodysplastic syndromes, from French-American- British to World Health Organization: comparison of classifications on 431 unselected patients from a single institution. Blood 2001;98(10):2935-2941.
    • (2001) Blood , vol.98 , Issue.10 , pp. 2935-2941
    • Nosslinger, T.1
  • 17
    • 0033757263 scopus 로고    scopus 로고
    • Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: A retrospective analysis of 1600 patients
    • Germing U, Gattermann N, Strupp C, Aivado M, Aul C. Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: a retrospective analysis of 1600 patients. Leuk Res 2000;24(12):983-992.
    • (2000) Leuk Res , vol.24 , Issue.12 , pp. 983-992
    • Germing, U.1    Gattermann, N.2    Strupp, C.3    Aivado, M.4    Aul, C.5
  • 18
    • 0037089225 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: From French-American-British to World Health Organization: A commentary
    • Bennett JM, Brunning RD, Vardiman JW. Myelodysplastic syndromes: from French-American-British to World Health Organization: a commentary. Blood 2002;99(8):3074-3075.
    • (2002) Blood , vol.99 , Issue.8 , pp. 3074-3075
    • Bennett, J.M.1    Brunning, R.D.2    Vardiman, J.W.3
  • 19
    • 0037093222 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: Prognostic significance of multilineage dysplasia in patients with refractory anemia or refractory anemia with ringed sideroblasts
    • author reply 3871
    • Dunkley SM, Manoharan A, Kwan YL. Myelodysplastic syndromes: prognostic significance of multilineage dysplasia in patients with refractory anemia or refractory anemia with ringed sideroblasts. Blood 2002;99(10): 3870-3871; author reply 3871.
    • (2002) Blood , vol.99 , Issue.10 , pp. 3870-3871
    • Dunkley, S.M.1    Manoharan, A.2    Kwan, Y.L.3
  • 21
    • 0023886688 scopus 로고
    • Prognostic factors in chronic myelodysplastic syndromes: A multivariate analysis in 107 cases
    • Garcia S, et al. Prognostic factors in chronic myelodysplastic syndromes: a multivariate analysis in 107 cases. Am J Hematol 1988;27(3):163-168.
    • (1988) Am J Hematol , vol.27 , Issue.3 , pp. 163-168
    • Garcia, S.1
  • 22
    • 0023881235 scopus 로고
    • Prognostic features of chronic myelomonocytic leukaemia: A modified Bournemouth score gives the best prediction of survival
    • Worsley A, et al. Prognostic features of chronic myelomonocytic leukaemia: a modified Bournemouth score gives the best prediction of survival. Br Haematol 1988;68(1):17-21.
    • (1988) Br Haematol , vol.68 , Issue.1 , pp. 17-21
    • Worsley, A.1
  • 23
    • 0026504855 scopus 로고
    • Primary myelodysplastic syndromes: Analysis of prognostic factors in 235 patients and proposals for an improved scoring system
    • Aul C, et al. Primary myelodysplastic syndromes: analysis of prognostic factors in 235 patients and proposals for an improved scoring system. Leukemia 1992;6(1):52-59.
    • (1992) Leukemia , vol.6 , Issue.1 , pp. 52-59
    • Aul, C.1
  • 24
    • 0027372507 scopus 로고
    • Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: A report on 408 cases
    • Morel P, et al. Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: a report on 408 cases. Leukemia 1993;7(9):1315-1323.
    • (1993) Leukemia , vol.7 , Issue.9 , pp. 1315-1323
    • Morel, P.1
  • 25
    • 0030897009 scopus 로고    scopus 로고
    • International scoring system for evaluating prognosis in myelodysplastic syndromes
    • Greenberg P, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997;89(6):2079-2088.
    • (1997) Blood , vol.89 , Issue.6 , pp. 2079-2088
    • Greenberg, P.1
  • 26
    • 0034174757 scopus 로고    scopus 로고
    • Myelodysplastic syndromes
    • Miller KB. Myelodysplastic syndromes. Curr Treat Options Oncol 2000;1(1):63-69.
    • (2000) Curr Treat Options Oncol , vol.1 , Issue.1 , pp. 63-69
    • Miller, K.B.1
  • 27
    • 0026569868 scopus 로고
    • Clinical features of MDS
    • Hamblin T. Clinical features of MDS. Leuk Res 1992; 16(1):89-93.
    • (1992) Leuk Res , vol.16 , Issue.1 , pp. 89-93
    • Hamblin, T.1
  • 28
    • 0030121938 scopus 로고    scopus 로고
    • Myelodysplastic syndromes
    • Koeffler HP. Myelodysplastic syndromes. Semin Hematol 1996;33(2):87-94.
    • (1996) Semin Hematol , vol.33 , Issue.2 , pp. 87-94
    • Koeffler, H.P.1
  • 29
    • 0033616140 scopus 로고    scopus 로고
    • Apoptosis in human disease: A new skin for the old ceremony?
    • Fadeel B, Orrenius S, Zhivotovsky B. Apoptosis in human disease: a new skin for the old ceremony? Biochem Biophys Res Commun 1999;266(3):699-717.
    • (1999) Biochem Biophys Res Commun , vol.266 , Issue.3 , pp. 699-717
    • Fadeel, B.1    Orrenius, S.2    Zhivotovsky, B.3
  • 30
    • 0032863163 scopus 로고    scopus 로고
    • All along the watch-tower: On the regulation of apoptosis regulators
    • Fadeel B, Zhivotovsky B, Orrenius S. All along the watch-tower: on the regulation of apoptosis regulators. FASEB J 1999;13(13):1647-1657.
    • (1999) FASEB J , vol.13 , Issue.13 , pp. 1647-1657
    • Fadeel, B.1    Zhivotovsky, B.2    Orrenius, S.3
  • 31
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. The biochemistry of apoptosis. Nature 2000;407(6805):770- 776.
    • (2000) Nature , vol.407 , Issue.6805 , pp. 770-776
    • Hengartner, M.O.1
  • 32
    • 0034536743 scopus 로고    scopus 로고
    • Regulation of death receptor-mediated apoptosis pathways
    • Schmitz I, Kirchhoff S, Krammer PH. Regulation of death receptor-mediated apoptosis pathways. Int J Biochem Cell Biol 2000;32(11-12):1123-1136.
    • (2000) Int J Biochem Cell Biol , vol.32 , Issue.11-12 , pp. 1123-1136
    • Schmitz, I.1    Kirchhoff, S.2    Krammer, P.H.3
  • 33
    • 0037069929 scopus 로고    scopus 로고
    • Chemotherapy: Targeting the mitochondrial cell death pathway
    • Debatin KM, Poncet D, Kroemer G. Chemotherapy: targeting the mitochondrial cell death pathway. Oncogene 2002;21(57):8786-8803.
    • (2002) Oncogene , vol.21 , Issue.57 , pp. 8786-8803
    • Debatin, K.M.1    Poncet, D.2    Kroemer, G.3
  • 35
  • 36
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998;281(5381):1309-1312.
    • (1998) Science , vol.281 , Issue.5381 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 37
  • 38
    • 0030773136 scopus 로고    scopus 로고
    • Implication of mitochondria in apoptosis
    • Petit PX, et al. Implication of mitochondria in apoptosis. Mol Cell Biochem 1997;174(1-2):185-188.
    • (1997) Mol Cell Biochem , vol.174 , Issue.1-2 , pp. 185-188
    • Petit, P.X.1
  • 39
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102(1): 33-42.
    • (2000) Cell , vol.102 , Issue.1 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 40
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: How Pandora's box opens
    • Zamzami N, Kroemer G. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2001;2(1):67-71.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , Issue.1 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2
  • 41
    • 0035349906 scopus 로고    scopus 로고
    • The genetics and pathology of oxidative phosphorylation
    • Smeitink J, van den Heuvel L, DiMauro S. The genetics and pathology of oxidative phosphorylation. Nat Rev Genet 2001;2(5):342-352.
    • (2001) Nat Rev Genet , vol.2 , Issue.5 , pp. 342-352
    • Smeitink, J.1    Van Den Heuvel, L.2    DiMauro, S.3
  • 42
    • 0034630187 scopus 로고    scopus 로고
    • The mitochondrion in cell death control: Certainties and incognita
    • Loeffler M, Kroemer G. The mitochondrion in cell death control: certainties and incognita. Exp Cell Res 2000; 256(1):19-26.
    • (2000) Exp Cell Res , vol.256 , Issue.1 , pp. 19-26
    • Loeffler, M.1    Kroemer, G.2
  • 44
    • 0033491193 scopus 로고    scopus 로고
    • CD95 (APO-1/Fas)-mediated apoptosis: Live and let die
    • Krammer PH. CD95 (APO-1/Fas)-mediated apoptosis: live and let die. Adv Immunol 1999;71:163-210.
    • (1999) Adv Immunol , vol.71 , pp. 163-210
    • Krammer, P.H.1
  • 46
    • 0027289648 scopus 로고
    • Myelodysplastic syndromes: From morphology to molecular biology. Part I. Classification, natural history and cell biology of myelodysplasia
    • Yoshida Y, Stephenson J, Mufti GJ. Myelodysplastic syndromes: from morphology to molecular biology. Part I. Classification, natural history and cell biology of myelodysplasia. Int J Hematol 1993;57(2):87-97.
    • (1993) Int J Hematol , vol.57 , Issue.2 , pp. 87-97
    • Yoshida, Y.1    Stephenson, J.2    Mufti, G.J.3
  • 47
    • 0029020851 scopus 로고
    • Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes
    • Raza A, et al. Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes. Blood 1995;86(1): 268-276.
    • (1995) Blood , vol.86 , Issue.1 , pp. 268-276
    • Raza, A.1
  • 48
    • 0032437584 scopus 로고    scopus 로고
    • "Low-risk" myelodysplastic syndrome is associated with excessive apoptosis and an increased ratio of pro- Versus anti-apoptotic bcl-2-related proteins
    • Parker JE, et al. "Low-risk" myelodysplastic syndrome is associated with excessive apoptosis and an increased ratio of pro- versus anti-apoptotic bcl-2-related proteins. Br J Haematol 1998;103(4):1075-1082.
    • (1998) Br J Haematol , vol.103 , Issue.4 , pp. 1075-1082
    • Parker, J.E.1
  • 49
    • 0034551738 scopus 로고    scopus 로고
    • The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS
    • Parker JE, et al. The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS. Blood 2000;96(12):3932-3938.
    • (2000) Blood , vol.96 , Issue.12 , pp. 3932-3938
    • Parker, J.E.1
  • 50
    • 0036113177 scopus 로고    scopus 로고
    • Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes
    • Boudard D, et al. Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes. Am J Hematol 2002;70(2):115-125.
    • (2002) Am J Hematol , vol.70 , Issue.2 , pp. 115-125
    • Boudard, D.1
  • 51
    • 18344401654 scopus 로고    scopus 로고
    • Morphological changes and apoptosis in bone marrow from patients with myelodysplastic syndromes treated with granulocyte-CSF and erythropoietin
    • Hellstrom-Lindberg E, Kanter-Lewensohn L, Ost A. Morphological changes and apoptosis in bone marrow from patients with myelodysplastic syndromes treated with granulocyte-CSF and erythropoietin. Leuk Res 1997;21(5):415-425.
    • (1997) Leuk Res , vol.21 , Issue.5 , pp. 415-425
    • Hellstrom-Lindberg, E.1    Kanter-Lewensohn, L.2    Ost, A.3
  • 52
    • 0032848438 scopus 로고    scopus 로고
    • Apoptosis in patients with myelodysplastic syndromes: Differential involvement of marrow cells in "good" versus "poor" prognosis patients and correlation with apoptosis-related genes
    • Tsoplou P, et al. Apoptosis in patients with myelodysplastic syndromes: differential involvement of marrow cells in "good" versus "poor" prognosis patients and correlation with apoptosis-related genes. Leukemia 1999;13(10):1554-1563.
    • (1999) Leukemia , vol.13 , Issue.10 , pp. 1554-1563
    • Tsoplou, P.1
  • 53
    • 0029957664 scopus 로고    scopus 로고
    • Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells
    • Rajapaksa R, Ginzton N, Rott LS, Greenberg PL. Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells. Blood 1996;88(11):4275-4287.
    • (1996) Blood , vol.88 , Issue.11 , pp. 4275-4287
    • Rajapaksa, R.1    Ginzton, N.2    Rott, L.S.3    Greenberg, P.L.4
  • 54
    • 0030926080 scopus 로고    scopus 로고
    • Fas/Apo-1 (CD95) expression and apoptosis in patients with myelodysplastic syndromes
    • Bouscary D, et al. Fas/Apo-1 (CD95) expression and apoptosis in patients with myelodysplastic syndromes. Leukemia 1997;11(6):839-845.
    • (1997) Leukemia , vol.11 , Issue.6 , pp. 839-845
    • Bouscary, D.1
  • 55
    • 17744389188 scopus 로고    scopus 로고
    • Expression and activity of caspases 1 and 3 in myelodysplastic syndromes
    • Boudard D, et al. Expression and activity of caspases 1 and 3 in myelodysplastic syndromes. Leukemia 2000;14(12):2045-2051.
    • (2000) Leukemia , vol.14 , Issue.12 , pp. 2045-2051
    • Boudard, D.1
  • 56
    • 0032933930 scopus 로고    scopus 로고
    • Biological characteristics of myelodysplastic syndrome patients who demonstrated high versus no intramedullary apoptosis
    • Dar S, et al. Biological characteristics of myelodysplastic syndrome patients who demonstrated high versus no intramedullary apoptosis. Eur J Haematol 1999;62(2):90-94.
    • (1999) Eur J Haematol , vol.62 , Issue.2 , pp. 90-94
    • Dar, S.1
  • 57
    • 0033781130 scopus 로고    scopus 로고
    • Evaluation of apoptosis as a prognostic factor in myelodysplastic syndromes
    • Shimazaki K, Ohshima K, Suzumiya J, Kawasaki C, Kikuchi M. Evaluation of apoptosis as a prognostic factor in myelodysplastic syndromes. Br J Haematol 2000; 110(3):584-590.
    • (2000) Br J Haematol , vol.110 , Issue.3 , pp. 584-590
    • Shimazaki, K.1    Ohshima, K.2    Suzumiya, J.3    Kawasaki, C.4    Kikuchi, M.5
  • 58
    • 0036213268 scopus 로고    scopus 로고
    • What does apoptosis have to do with clinical features in myelodysplastic syndrome?
    • Ramos F, Fuertes-Nunez M, Suarez-Vilela D, Fernandez-Lopez A. What does apoptosis have to do with clinical features in myelodysplastic syndrome? Haematologica 2002;87(4):381-391.
    • (2002) Haematologica , vol.87 , Issue.4 , pp. 381-391
    • Ramos, F.1    Fuertes-Nunez, M.2    Suarez-Vilela, D.3    Fernandez-Lopez, A.4
  • 59
    • 0030999750 scopus 로고    scopus 로고
    • Apoptosis and the dilemma of cancer chemotherapy
    • Hannun YA. Apoptosis and the dilemma of cancer chemotherapy. Blood 1997;89(6):1845-1853.
    • (1997) Blood , vol.89 , Issue.6 , pp. 1845-1853
    • Hannun, Y.A.1
  • 60
    • 0032408713 scopus 로고    scopus 로고
    • Apoptosis and its role in the myelodysplastic syndromes: Implications for disease natural history and treatment
    • Greenberg PL. Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment. Leuk Res 1998;22(12):1123-1136.
    • (1998) Leuk Res , vol.22 , Issue.12 , pp. 1123-1136
    • Greenberg, P.L.1
  • 61
    • 17144441932 scopus 로고    scopus 로고
    • Evidence for involvement of tumor necrosis factor-alpha in apoptotic death of bone marrow cells in myelodysplastic syndromes
    • Mundle SD, et al. Evidence for involvement of tumor necrosis factor-alpha in apoptotic death of bone marrow cells in myelodysplastic syndromes. Am J Hematol 1999;60(1):36-47.
    • (1999) Am J Hematol , vol.60 , Issue.1 , pp. 36-47
    • Mundle, S.D.1
  • 62
    • 0029048258 scopus 로고
    • Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia
    • Maciejewski JP, Selleri C, Sato T, Anderson S, Young NS. Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia. Br J Haematol 1995;91(1):245-252.
    • (1995) Br J Haematol , vol.91 , Issue.1 , pp. 245-252
    • Maciejewski, J.P.1    Selleri, C.2    Sato, T.3    Anderson, S.4    Young, N.S.5
  • 63
    • 0029965280 scopus 로고    scopus 로고
    • FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
    • Chinnaiyan AM, et al. FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem 1996;271(9):4961-4965.
    • (1996) J Biol Chem , vol.271 , Issue.9 , pp. 4961-4965
    • Chinnaiyan, A.M.1
  • 64
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998;281(5381):1305-1308.
    • (1998) Science , vol.281 , Issue.5381 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 65
    • 0032950951 scopus 로고    scopus 로고
    • Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis
    • De Maria R, et al. Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis. Blood 1999;93(3): 796-803.
    • (1999) Blood , vol.93 , Issue.3 , pp. 796-803
    • De Maria, R.1
  • 66
    • 0029166876 scopus 로고
    • Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells
    • Nagafuji K, et al. Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells. Blood 1995; 86(3):883-889.
    • (1995) Blood , vol.86 , Issue.3 , pp. 883-889
    • Nagafuji, K.1
  • 67
    • 0031656518 scopus 로고    scopus 로고
    • A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome
    • Gersuk GM, et al. A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome. Br J Haematol 1998;103(1): 176-188.
    • (1998) Br J Haematol , vol.103 , Issue.1 , pp. 176-188
    • Gersuk, G.M.1
  • 68
    • 0031845360 scopus 로고    scopus 로고
    • Fas/APO-1 (CD95) expression in myelodysplastic syndromes
    • Lepelley P, et al. Fas/APO-1 (CD95) expression in myelodysplastic syndromes. Leuk Lymphoma 1998;30(3-4): 307-312.
    • (1998) Leuk Lymphoma , vol.30 , Issue.3-4 , pp. 307-312
    • Lepelley, P.1
  • 69
    • 0035100089 scopus 로고    scopus 로고
    • Apoptosis in refractory anaemia with ringed sideroblasts is initiated at the stem cell level and associated with increased activation of caspases
    • Hellstrom-Lindberg E, Schmidt-Mende J, Forsblom AM, Christensson B, Fadeel B, Zhivotovsky B. Apoptosis in refractory anaemia with ringed sideroblasts is initiated at the stem cell level and associated with increased activation of caspases. Br J Haematol 2001;112(3):714-726.
    • (2001) Br J Haematol , vol.112 , Issue.3 , pp. 714-726
    • Hellstrom-Lindberg, E.1    Schmidt-Mende, J.2    Forsblom, A.M.3    Christensson, B.4    Fadeel, B.5    Zhivotovsky, B.6
  • 70
    • 85009895235 scopus 로고    scopus 로고
    • TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors
    • Plasilova M, et al. TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors. Leukemia 2002;16(1):67-73.
    • (2002) Leukemia , vol.16 , Issue.1 , pp. 67-73
    • Plasilova, M.1
  • 71
    • 0035892123 scopus 로고    scopus 로고
    • Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: Effects on in vitro hemopoiesis
    • Zang DY, Goodwin RG, Loken MR, Bryant E, Deeg HJ. Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: effects on in vitro hemopoiesis. Blood 2001;98(10):3058-3065.
    • (2001) Blood , vol.98 , Issue.10 , pp. 3058-3065
    • Zang, D.Y.1    Goodwin, R.G.2    Loken, M.R.3    Bryant, E.4    Deeg, H.J.5
  • 72
    • 0035013475 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor inhibits Fas-triggered apoptosis in bone marrow cells isolated from patients with refractory anemia with ringed sideroblasts
    • Schmidt-Mende J, et al. Granulocyte colony-stimulating factor inhibits Fas-triggered apoptosis in bone marrow cells isolated from patients with refractory anemia with ringed sideroblasts. Leukemia 2001;15(5):742-751.
    • (2001) Leukemia , vol.15 , Issue.5 , pp. 742-751
    • Schmidt-Mende, J.1
  • 73
    • 0032744065 scopus 로고    scopus 로고
    • Sequential activation of caspase-1 and caspase-3-like proteases during apoptosis in myelodysplastic syndromes
    • Ali A, et al. Sequential activation of caspase-1 and caspase-3-like proteases during apoptosis in myelodysplastic syndromes. J Hematother Stem Cell Res 1999;8(4):343-356.
    • (1999) J Hematother Stem Cell Res , vol.8 , Issue.4 , pp. 343-356
    • Ali, A.1
  • 74
    • 0033176431 scopus 로고    scopus 로고
    • Spontaneous down-regulation of Fas-associated phosphatase-1 may contribute to excessive apoptosis in myelodysplastic marrows
    • Mundle SD, et al. Spontaneous down-regulation of Fas-associated phosphatase-1 may contribute to excessive apoptosis in myelodysplastic marrows. Int J Hematol 1999;70(2):83-90.
    • (1999) Int J Hematol , vol.70 , Issue.2 , pp. 83-90
    • Mundle, S.D.1
  • 75
    • 0034051401 scopus 로고    scopus 로고
    • Activity of the caspase-3/CPP32 enzyme is increased in "early stage" myelodysplastic syndromes with excessive apoptosis, but caspase inhibition does not enhance colony formation in vitro
    • Bouscary D, et al. Activity of the caspase-3/CPP32 enzyme is increased in "early stage" myelodysplastic syndromes with excessive apoptosis, but caspase inhibition does not enhance colony formation in vitro. Exp Hematol 2000;28(7):784-791.
    • (2000) Exp Hematol , vol.28 , Issue.7 , pp. 784-791
    • Bouscary, D.1
  • 76
    • 20844462217 scopus 로고    scopus 로고
    • Rescue of early stage myelodysplastic syndrome-deriving erythroid precursors by the ectopic expression of a dominant negative form of FADD
    • Claessens YE, et al. Rescue of early stage myelodysplastic syndrome-deriving erythroid precursors by the ectopic expression of a dominant negative form of FADD. Blood 2005;105(10):4035-4042.
    • (2005) Blood , vol.105 , Issue.10 , pp. 4035-4042
    • Claessens, Y.E.1
  • 77
    • 0037307728 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors
    • Tehranchi R, et al. Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors. Blood 2003;101(3):1080-1086.
    • (2003) Blood , vol.101 , Issue.3 , pp. 1080-1086
    • Tehranchi, R.1
  • 78
    • 15844405224 scopus 로고    scopus 로고
    • Novel insights into the biology of myelodysplastic syndromes: Excessive apoptosis and the role of cytokines
    • Raza A, et al. Novel insights into the biology of myelodysplastic syndromes: excessive apoptosis and the role of cytokines. Int J Hematol 1996;63(4):265-278.
    • (1996) Int J Hematol , vol.63 , Issue.4 , pp. 265-278
    • Raza, A.1
  • 79
    • 0034254254 scopus 로고    scopus 로고
    • Anti-TNF therapies in rheumatoid arthritis, Crohn's disease, sepsis, and myelodysplastic syndromes
    • Raza A. Anti-TNF therapies in rheumatoid arthritis, Crohn's disease, sepsis, and myelodysplastic syndromes. Microsc Res Tech 2000;50(3):229-235.
    • (2000) Microsc Res Tech , vol.50 , Issue.3 , pp. 229-235
    • Raza, A.1
  • 80
    • 0027086859 scopus 로고
    • Measurement of serum cytokine levels in patients with myelodysplastic syndromes
    • Verhoef GE, et al. Measurement of serum cytokine levels in patients with myelodysplastic syndromes. Leukemia 1992;6(12):1268-1272.
    • (1992) Leukemia , vol.6 , Issue.12 , pp. 1268-1272
    • Verhoef, G.E.1
  • 81
    • 0028000565 scopus 로고
    • Low serum levels of tumor necrosis factor and interleukin-1 beta in myelodysplastic syndromes responsive to recombinant erythropoietin
    • Musto P, et al. Low serum levels of tumor necrosis factor and interleukin-1 beta in myelodysplastic syndromes responsive to recombinant erythropoietin. Haematologica 1994;79(3):265-268.
    • (1994) Haematologica , vol.79 , Issue.3 , pp. 265-268
    • Musto, P.1
  • 82
    • 0006372543 scopus 로고    scopus 로고
    • Biological consequences of stromal abnormalities in the myelodysplastic syndrome (MDS): Its influence on the hematopoietic dysregulation
    • Silverman LR, Zinzar S, Holland JF. Biological consequences of stromal abnormalities in the myelodysplastic syndrome (MDS): Its influence on the hematopoietic dysregulation. Leuk Res 1997;21(1, Supplement 1):S20.
    • (1997) Leuk Res , vol.21 , Issue.1 SUPPL. 1
    • Silverman, L.R.1    Zinzar, S.2    Holland, J.F.3
  • 83
    • 0032941565 scopus 로고    scopus 로고
    • Bone marrow stroma from refractory anemia of myelodysplastic syndrome is defective in its ability to support normal CD34-positive cell proliferation and differentiation in vitro
    • Aizawa S, et al. Bone marrow stroma from refractory anemia of myelodysplastic syndrome is defective in its ability to support normal CD34-positive cell proliferation and differentiation in vitro. Leuk Res 1999;23(3):239-246.
    • (1999) Leuk Res , vol.23 , Issue.3 , pp. 239-246
    • Aizawa, S.1
  • 84
    • 0034490531 scopus 로고    scopus 로고
    • Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia
    • Tennant GB, et al. Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia. Br J Haematol 2000;111(3):853-862.
    • (2000) Br J Haematol , vol.111 , Issue.3 , pp. 853-862
    • Tennant, G.B.1
  • 85
    • 0031004494 scopus 로고    scopus 로고
    • Incidence and role of apoptosis in myelodysplastic syndrome: Morphological and ultrastructural assessment
    • Bogdanovic AD, et al. Incidence and role of apoptosis in myelodysplastic syndrome: morphological and ultrastructural assessment. Leukemia 1997;11(5):656-659.
    • (1997) Leukemia , vol.11 , Issue.5 , pp. 656-659
    • Bogdanovic, A.D.1
  • 86
    • 0031015630 scopus 로고    scopus 로고
    • Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia
    • Kuhl JS, Krajewski S, Duran GE, Reed JC, Sikic BI. Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia. Br J Cancer 1997;75(2):268-274.
    • (1997) Br J Cancer , vol.75 , Issue.2 , pp. 268-274
    • Kuhl, J.S.1    Krajewski, S.2    Duran, G.E.3    Reed, J.C.4    Sikic, B.I.5
  • 87
    • 0032892867 scopus 로고    scopus 로고
    • Significance of electron-dense deposits in the mitochondrial matrix of erythroid precursors in aplastic anaemia and myelodysplastic syndrome
    • Bessho F, Ohnishi H, Tabuchi K, Kobayashi M, Hayashi Y. Significance of electron-dense deposits in the mitochondrial matrix of erythroid precursors in aplastic anaemia and myelodysplastic syndrome. Br J Haematol 1999;105(1): 149-154.
    • (1999) Br J Haematol , vol.105 , Issue.1 , pp. 149-154
    • Bessho, F.1    Ohnishi, H.2    Tabuchi, K.3    Kobayashi, M.4    Hayashi, Y.5
  • 88
    • 0035075298 scopus 로고    scopus 로고
    • Mitochondrial disruption and limited apoptosis of erythroblasts are associated with high risk myelodysplasia. An ultrastructural analysis
    • van de Loosdrecht AA, et al. Mitochondrial disruption and limited apoptosis of erythroblasts are associated with high risk myelodysplasia. An ultrastructural analysis. Leuk Res 2001;25(5):385-393.
    • (2001) Leuk Res , vol.25 , Issue.5 , pp. 385-393
    • Van De Loosdrecht, A.A.1
  • 89
    • 0033565557 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and its role in cell death
    • Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J 1999;341(Pt 2):233-249.
    • (1999) Biochem J , vol.341 , Issue.2 PART , pp. 233-249
    • Crompton, M.1
  • 90
    • 0034494799 scopus 로고    scopus 로고
    • Increased apoptosis in acquired sideroblastic anaemia
    • Matthes TW, Meyer G, Samii K, Beris P. Increased apoptosis in acquired sideroblastic anaemia. Br J Haematol 2000;111(3):843-852.
    • (2000) Br J Haematol , vol.111 , Issue.3 , pp. 843-852
    • Matthes, T.W.1    Meyer, G.2    Samii, K.3    Beris, P.4
  • 91
    • 0034142678 scopus 로고    scopus 로고
    • From sideroblastic anemia to the role of mitochondrial DNA mutations in myelodysplastic syndromes
    • Gattermann N. From sideroblastic anemia to the role of mitochondrial DNA mutations in myelodysplastic syndromes. Leuk Res 2000;24(2):141-151.
    • (2000) Leuk Res , vol.24 , Issue.2 , pp. 141-151
    • Gattermann, N.1
  • 92
    • 0019423856 scopus 로고
    • Sequence and organization of the human mitochondrial genome
    • Anderson S, et al. Sequence and organization of the human mitochondrial genome. Nature 1981;290(5806):457-465.
    • (1981) Nature , vol.290 , Issue.5806 , pp. 457-465
    • Anderson, S.1
  • 93
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • Richter C, Park JW, Ames BN. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci USA 1988;85(17):6465-6467.
    • (1988) Proc Natl Acad Sci USA , vol.85 , Issue.17 , pp. 6465-6467
    • Richter, C.1    Park, J.W.2    Ames, B.N.3
  • 94
    • 0030990904 scopus 로고    scopus 로고
    • Mitochondrial DNA amplification in AML: A hypothesis
    • Gattermann N, Aul C. Mitochondrial DNA amplification in AML: a hypothesis. Br J Haematol 1997;97(1):242.
    • (1997) Br J Haematol , vol.97 , Issue.1 , pp. 242
    • Gattermann, N.1    Aul, C.2
  • 95
    • 0033060854 scopus 로고    scopus 로고
    • The mitochondrial genome: Structure, transcription, translation and replication
    • Taanman JW. The mitochondrial genome: structure, transcription, translation and replication. Biochim Biophys Acta 1999;1410(2):103-123.
    • (1999) Biochim Biophys Acta , vol.1410 , Issue.2 , pp. 103-123
    • Taanman, J.W.1
  • 96
    • 0038281403 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in patients with myelodysplastic syndromes
    • Shin MG, Kajigaya S, Levin BC, Young NS. Mitochondrial DNA mutations in patients with myelodysplastic syndromes. Blood 2003;101(8):3118-3125.
    • (2003) Blood , vol.101 , Issue.8 , pp. 3118-3125
    • Shin, M.G.1    Kajigaya, S.2    Levin, B.C.3    Young, N.S.4
  • 97
    • 2942563746 scopus 로고    scopus 로고
    • Mitochondrial DNA sequence heterogeneity in circulating normal human CD34 cells and granulocytes
    • Shin MG, et al. Mitochondrial DNA sequence heterogeneity in circulating normal human CD34 cells and granulocytes. Blood 2004;103(12):4466-4477.
    • (2004) Blood , vol.103 , Issue.12 , pp. 4466-4477
    • Shin, M.G.1
  • 98
    • 0036493359 scopus 로고    scopus 로고
    • In vitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: Evidence for Fas-dependent apoptosis
    • Claessens Y-E, et al. In vitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: evidence for Fas-dependent apoptosis. Blood 2002;99(5):1594-1601.
    • (2002) Blood , vol.99 , Issue.5 , pp. 1594-1601
    • Claessens, Y.-E.1
  • 99
    • 33646868263 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor and erythropoietin treatment in MDS: A comparison of in vitro and in vivo effects on apoptosis and clonal growth
    • Tehranchi R, et al. Granulocyte colony-stimulating factor and erythropoietin treatment in MDS: A comparison of in vitro and in vivo effects on apoptosis and clonal growth. Leuk Res 2003;27(Suppl. 1):S71-72.
    • (2003) Leuk Res , vol.27 , Issue.1 SUPPL.
    • Tehranchi, R.1
  • 100
    • 0242422377 scopus 로고    scopus 로고
    • Mitochondrial ferritin: A new player in iron metabolism
    • Drysdale J, et al. Mitochondrial ferritin: a new player in iron metabolism. Blood Cells Mol Dis 2002;29(3):376-383.
    • (2002) Blood Cells Mol Dis , vol.29 , Issue.3 , pp. 376-383
    • Drysdale, J.1
  • 101
    • 0037372442 scopus 로고    scopus 로고
    • Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia
    • Cazzola M, et al. Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia. Blood 2003;101(5):1996-2000.
    • (2003) Blood , vol.101 , Issue.5 , pp. 1996-2000
    • Cazzola, M.1
  • 102
    • 22044434111 scopus 로고    scopus 로고
    • Aberrant mitochondrial iron distribution and maturation arrest characterizes early erythroid precursors in low-risk myelodysplastic syndromes
    • Tehranchi R, et al. Aberrant mitochondrial iron distribution and maturation arrest characterizes early erythroid precursors in low-risk myelodysplastic syndromes. Blood 2005; 106(1):247-253.
    • (2005) Blood , vol.106 , Issue.1 , pp. 247-253
    • Tehranchi, R.1
  • 103
    • 14944358625 scopus 로고    scopus 로고
    • Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis
    • Nie G, Sheftel AD, Kim SF, Ponka P. Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis. Blood 2005;105(5): 2161-2167.
    • (2005) Blood , vol.105 , Issue.5 , pp. 2161-2167
    • Nie, G.1    Sheftel, A.D.2    Kim, S.F.3    Ponka, P.4
  • 104
    • 0035480007 scopus 로고    scopus 로고
    • Hematopoietic development: A balancing act
    • Cantor AB, Orkin SH. Hematopoietic development: a balancing act. Curr Opin Genet Dev 2001;11(5):513-519.
    • (2001) Curr Opin Genet Dev , vol.11 , Issue.5 , pp. 513-519
    • Cantor, A.B.1    Orkin, S.H.2
  • 105
    • 0037071383 scopus 로고    scopus 로고
    • Transcriptional regulation of erythropoiesis: An affair involving multiple partners
    • Cantor AB, Orkin SH. Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene 2002;21(21):3368-3376.
    • (2002) Oncogene , vol.21 , Issue.21 , pp. 3368-3376
    • Cantor, A.B.1    Orkin, S.H.2
  • 106
    • 0031035425 scopus 로고    scopus 로고
    • Erythropoietin-induced activation of STAT5 is impaired in the myelodysplastic syndrome
    • Hoefsloot LH, et al. Erythropoietin-induced activation of STAT5 is impaired in the myelodysplastic syndrome. Blood 1997;89(5):1690-1700.
    • (1997) Blood , vol.89 , Issue.5 , pp. 1690-1700
    • Hoefsloot, L.H.1
  • 107
    • 0033619265 scopus 로고    scopus 로고
    • Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1
    • De Maria R, et al. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature 1999; 401(6752):489-493.
    • (1999) Nature , vol.401 , Issue.6752 , pp. 489-493
    • De Maria, R.1
  • 108
    • 0032863499 scopus 로고    scopus 로고
    • Ineffective erythropoiesis in myelodysplastic syndromes: Correlation with Fas expression but not with lack of erythropoietin receptor signal transduction
    • Fontenay-Roupie M, et al. Ineffective erythropoiesis in myelodysplastic syndromes: correlation with Fas expression but not with lack of erythropoietin receptor signal transduction. Br J Haematol 1999;106(2):464-473.
    • (1999) Br J Haematol , vol.106 , Issue.2 , pp. 464-473
    • Fontenay-Roupie, M.1
  • 109
    • 0028275077 scopus 로고
    • Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the Gl and S phases of the cell cycle without growth arrest or stabilization of wild-type p53
    • Kelley LL, et al. Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the Gl and S phases of the cell cycle without growth arrest or stabilization of wild-type p53. Mol Cell Biol 1994;14(6):4183-4192.
    • (1994) Mol Cell Biol , vol.14 , Issue.6 , pp. 4183-4192
    • Kelley, L.L.1
  • 110
    • 0027360191 scopus 로고
    • Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: A mechanism for controlled rates of erythrocyte production
    • Kelley LL, et al. Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production. Blood 1993;82(8):2340-2352.
    • (1993) Blood , vol.82 , Issue.8 , pp. 2340-2352
    • Kelley, L.L.1
  • 111
    • 0033890345 scopus 로고    scopus 로고
    • Stem cell factor and erythropoietin inhibit apoptosis of human erythroid progenitor cells through different signalling pathways
    • Sui X, Krantz SB, Zhao ZJ. Stem cell factor and erythropoietin inhibit apoptosis of human erythroid progenitor cells through different signalling pathways. Br J Haematol 2000;110(1):63-70.
    • (2000) Br J Haematol , vol.110 , Issue.1 , pp. 63-70
    • Sui, X.1    Krantz, S.B.2    Zhao, Z.J.3
  • 112
    • 0035127294 scopus 로고    scopus 로고
    • The granulocyte colony-stimulating factor receptor supports erythroid differentiation in the absence of the erythropoietin receptor or Stat5
    • Millot GA, Svinarchuk F, Lacout C, Vainchenker W, Dumenil D. The granulocyte colony-stimulating factor receptor supports erythroid differentiation in the absence of the erythropoietin receptor or Stat5. Br J Haematol 2001;112(2):449-458.
    • (2001) Br J Haematol , vol.112 , Issue.2 , pp. 449-458
    • Millot, G.A.1    Svinarchuk, F.2    Lacout, C.3    Vainchenker, W.4    Dumenil, D.5
  • 113
    • 0025370701 scopus 로고
    • Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor
    • Negrin R, et al. Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor. Blood 1990;76(1):36-43.
    • (1990) Blood , vol.76 , Issue.1 , pp. 36-43
    • Negrin, R.1
  • 114
    • 0000225805 scopus 로고
    • Randomized phase II study of recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with neutropenia secondary to myelodysplastic syndrome (MDS)
    • Shuster MW, Thompson JA, Larson RA, Dugan. Randomized phase II study of recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with neutropenia secondary to myelodysplastic syndrome (MDS). Blood 1995;86:338a.
    • (1995) Blood , vol.86
    • Shuster, M.W.1    Thompson, J.A.2    Larson, R.A.3    Dugan4
  • 115
    • 0000399876 scopus 로고
    • Phase-III randomized multicenter trial of G-CSF vs observation for myelodysplastic syndromes (MDS)
    • Greenberg P, et al. Phase-III randomized multicenter trial of G-CSF vs observation for myelodysplastic syndromes (MDS). Blood 1993;82 (Suppl. 1)(10):A196.
    • (1993) Blood , vol.82 , Issue.1-10 SUPPL.
    • Greenberg, P.1
  • 116
    • 0025735327 scopus 로고
    • Recombinant human erythropoietin in patients with myelodysplastic syndromes
    • Schouten HC, et al. Recombinant human erythropoietin in patients with myelodysplastic syndromes. Leukemia 1991;5(5):432-436.
    • (1991) Leukemia , vol.5 , Issue.5 , pp. 432-436
    • Schouten, H.C.1
  • 117
    • 0028953367 scopus 로고
    • Efficacy of erythropoietin in the myelodysplastic syndromes: A meta-analysis of 205 patients from 17 studies
    • Hellstrom-Lindberg E. Efficacy of erythropoietin in the myelodysplastic syndromes: a meta-analysis of 205 patients from 17 studies. Br J Haematol 1995;89(1):67-71.
    • (1995) Br J Haematol , vol.89 , Issue.1 , pp. 67-71
    • Hellstrom-Lindberg, E.1
  • 118
    • 0028900601 scopus 로고
    • The use of r-HuEpo in the treatment of anaemia related to myelodysplasia (MDS)
    • Rose EH, Abels RI, Nelson RA, McCullough DM, Lessin L. The use of r-HuEpo in the treatment of anaemia related to myelodysplasia (MDS). Br J Haematol 1995;89(4):831-837.
    • (1995) Br J Haematol , vol.89 , Issue.4 , pp. 831-837
    • Rose, E.H.1    Abels, R.I.2    Nelson, R.A.3    McCullough, D.M.4    Lessin, L.5
  • 119
    • 0030958668 scopus 로고    scopus 로고
    • Response to recombinant human erythropoietin in patients with myelodysplastic syndromes
    • Stasi R, et al. Response to recombinant human erythropoietin in patients with myelodysplastic syndromes. Clin Cancer Res 1997;3(5):733-739.
    • (1997) Clin Cancer Res , vol.3 , Issue.5 , pp. 733-739
    • Stasi, R.1
  • 120
    • 0032409909 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled study with subcutaneous recombinant human erythropoietin in patients with low-risk myelodysplastic syndromes
    • Italian Cooperative Study Group for rHuEpo in Myelodysplastic Syndromes
    • Italian Cooperative Study Group for rHuEpo in Myelodysplastic Syndromes. A randomized double-blind placebo-controlled study with subcutaneous recombinant human erythropoietin in patients with low-risk myelodysplastic syndromes. Italian Cooperative Study Group for rHuEpo in Myelodysplastic Syndromes. Br J Haematol 1998;103(4):1070-1074.
    • (1998) Br J Haematol , vol.103 , Issue.4 , pp. 1070-1074
  • 121
    • 0035179679 scopus 로고    scopus 로고
    • Long-term follow-up of 18 patients with myelodysplastic syndromes responding to recombinant erythropoietin treatment
    • Hast R, Wallvik J, Folin A, Bernell P, Stenke L. Long-term follow-up of 18 patients with myelodysplastic syndromes responding to recombinant erythropoietin treatment. Leuk Res 2001;25(1):13-18.
    • (2001) Leuk Res , vol.25 , Issue.1 , pp. 13-18
    • Hast, R.1    Wallvik, J.2    Folin, A.3    Bernell, P.4    Stenke, L.5
  • 122
    • 0027361750 scopus 로고
    • A combination of granulocyte colony-stimulating factor and erythropoietin may synergistically improve the anaemia in patients with myelodysplastic syndromes
    • Hellstrom-Lindberg E, et al. A combination of granulocyte colony-stimulating factor and erythropoietin may synergistically improve the anaemia in patients with myelodysplastic syndromes. Leuk Lymph 1993;11(3-4):221-228.
    • (1993) Leuk Lymph , vol.11 , Issue.3-4 , pp. 221-228
    • Hellstrom-Lindberg, E.1
  • 123
    • 0029940725 scopus 로고    scopus 로고
    • Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: Evidence for in vivo synergy
    • Negrin RS, et al. Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: evidence for in vivo synergy. Blood 1996;87(10):4076-4081.
    • (1996) Blood , vol.87 , Issue.10 , pp. 4076-4081
    • Negrin, R.S.1
  • 124
    • 17544392895 scopus 로고    scopus 로고
    • Erythropoietin plus granulocyte colony-stimulating factor in the treatment of myelodysplastic syndromes. Identification of a subgroup of responders
    • The Spanish Erythropathology Group
    • Remacha AF, et al. Erythropoietin plus granulocyte colony-stimulating factor in the treatment of myelodysplastic syndromes. Identification of a subgroup of responders. The Spanish Erythropathology Group. Haematologica 1999; 84(12):1058-1064.
    • (1999) Haematologica , vol.84 , Issue.12 , pp. 1058-1064
    • Remacha, A.F.1
  • 125
    • 0034043581 scopus 로고    scopus 로고
    • Treatment of anaemia in myelodysplastic syndromes with prolonged administration of recombinant human granulocyte colony-stimulating factor and erythropoietin
    • Mantovani L, et al. Treatment of anaemia in myelodysplastic syndromes with prolonged administration of recombinant human granulocyte colony-stimulating factor and erythropoietin. Br J Haematol 2000;109(2):367-375.
    • (2000) Br J Haematol , vol.109 , Issue.2 , pp. 367-375
    • Mantovani, L.1
  • 126
    • 0036268260 scopus 로고    scopus 로고
    • The place of growth factors in the treatment of myelodysplastic syndromes
    • Ugo V, Casadevall N. [The place of growth factors in the treatment of myelodysplastic syndromes]. Pathol Biol (Paris) 2002;50(4):268-274.
    • (2002) Pathol Biol (Paris) , vol.50 , Issue.4 , pp. 268-274
    • Ugo, V.1    Casadevall, N.2
  • 127
    • 3142619150 scopus 로고    scopus 로고
    • Health, economic, and quality-of-life effects of erythropoietin and granulocyte colony-stimulating factor for the treatment of myelodysplastic syndromes: A randomized, controlled trial
    • Casadevall N, et al. Health, economic, and quality-of-life effects of erythropoietin and granulocyte colony-stimulating factor for the treatment of myelodysplastic syndromes: a randomized, controlled trial. Blood 2004;104(2): 321-327.
    • (2004) Blood , vol.104 , Issue.2 , pp. 321-327
    • Casadevall, N.1
  • 128
    • 0141887123 scopus 로고    scopus 로고
    • Approach to anemia associated with myelodysplastic syndromes
    • Hellstrom-Lindberg E. Approach to anemia associated with myelodysplastic syndromes. Curr Hematol Rep 2003;2(2):122-129.
    • (2003) Curr Hematol Rep , vol.2 , Issue.2 , pp. 122-129
    • Hellstrom-Lindberg, E.1
  • 129
    • 3042741335 scopus 로고    scopus 로고
    • Treatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor and erythropoetin: Response and impact on survival in a long-term follow-up of 129 patients
    • Jadersten M, et al. Treatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor and erythropoetin: response and impact on survival in a long-term follow-up of 129 patients. Blood 2003;102(11): 184-5a.
    • (2003) Blood , vol.102 , Issue.11
    • Jadersten, M.1
  • 130
    • 0026699167 scopus 로고
    • Kit ligand improves in vitro erythropoiesis in myelodysplastic syndrome
    • Backx B, Broeders L, Lowenberg B. Kit ligand improves in vitro erythropoiesis in myelodysplastic syndrome. Blood 1992;80(5):1213-1217.
    • (1992) Blood , vol.80 , Issue.5 , pp. 1213-1217
    • Backx, B.1    Broeders, L.2    Lowenberg, B.3
  • 131
    • 0032794124 scopus 로고    scopus 로고
    • Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39
    • Hassan Z, Fadeel B, Zhivotovsky B, Hellstrom-Lindberg E. Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39. Exp Hematol 1999;27(8):1322-1329.
    • (1999) Exp Hematol , vol.27 , Issue.8 , pp. 1322-1329
    • Hassan, Z.1    Fadeel, B.2    Zhivotovsky, B.3    Hellstrom-Lindberg, E.4
  • 132
    • 0025885415 scopus 로고
    • Granulocyte colony-stimulating factor and its receptor
    • Demetri GD, Griffin JD. Granulocyte colony-stimulating factor and its receptor. Blood 1991;78(11):2791-2808.
    • (1991) Blood , vol.78 , Issue.11 , pp. 2791-2808
    • Demetri, G.D.1    Griffin, J.D.2
  • 133
    • 0036070180 scopus 로고    scopus 로고
    • Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment
    • Miyamoto T, et al. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev Cell 2002;3(1):137-147.
    • (2002) Dev Cell , vol.3 , Issue.1 , pp. 137-147
    • Miyamoto, T.1
  • 134
    • 19744364850 scopus 로고    scopus 로고
    • Hypochromic red blood cells in low-risk myelodysplastic syndromes: Effects of treatment with pro-erythroid growth factors
    • Ljung T, Bäck R, Hellstrom Lindberg E. Hypochromic red blood cells in low-risk myelodysplastic syndromes: effects of treatment with pro-erythroid growth factors. Haematologica 2004;89(12):1446-1453.
    • (2004) Haematologica , vol.89 , Issue.12 , pp. 1446-1453
    • Ljung, T.1    Bäck, R.2    Hellstrom Lindberg, E.3
  • 135
    • 0034665776 scopus 로고    scopus 로고
    • Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: Evidence for involvement at the hematopoietic stem cell level
    • Nilsson L, et al. Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level. Blood 2000;96(6): 2012-2021.
    • (2000) Blood , vol.96 , Issue.6 , pp. 2012-2021
    • Nilsson, L.1
  • 136
    • 0036433664 scopus 로고    scopus 로고
    • rHuEpo administration in patients with low-risk myelodysplastic syndromes: Evaluation of erythroid precursors' response by fluorescence in situ hybridization on May-Grunwald-Giemsa-stained bone marrow samples
    • Rigolin GM, et al. rHuEpo administration in patients with low-risk myelodysplastic syndromes: evaluation of erythroid precursors' response by fluorescence in situ hybridization on May-Grunwald-Giemsa-stained bone marrow samples. Br J Haematol 2002;119(3):652-659.
    • (2002) Br J Haematol , vol.119 , Issue.3 , pp. 652-659
    • Rigolin, G.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.