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Volumn 69, Issue 4, 2003, Pages 1109-1117

Ammonium induces aberrant blastocyst differentiation, metabolism, pH regulation, gene expression and subsequently alters fetal development in the mouse

Author keywords

Assisted reproductive technology; Early development; In vitro fertilization

Indexed keywords

AMMONIA;

EID: 0141683784     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.103.018093     Document Type: Article
Times cited : (194)

References (64)
  • 1
    • 14544272393 scopus 로고
    • Culture of preimplantation embryos: Facts and artifacts
    • Bavister BD. Culture of preimplantation embryos: facts and artifacts. Hum Reprod Update 1995; 1:91-148.
    • (1995) Hum Reprod Update , vol.1 , pp. 91-148
    • Bavister, B.D.1
  • 2
    • 85131482322 scopus 로고    scopus 로고
    • Embryo culture systems
    • Trounson AO, Gardner DK (eds.). Boca Raton, FL: CRC Press
    • Gardner DK, Lane M. Embryo culture systems. In: Trounson AO, Gardner DK (eds.), Handbook of In Vitro Fertilization, 2nd ed. Boca Raton, FL: CRC Press; 1999:205-264.
    • (1999) Handbook of In Vitro Fertilization, 2nd Ed. , pp. 205-264
    • Gardner, D.K.1    Lane, M.2
  • 3
    • 0037600175 scopus 로고    scopus 로고
    • Development of viable mammalian embryos in vitro: Evolution of sequential media
    • Cibelli J, Lanza R, Campbell K, West MD (eds.). San Diego: Elsevier Science
    • Gardner DK, Lane M. Development of viable mammalian embryos in vitro: evolution of sequential media. In: Cibelli J, Lanza R, Campbell K, West MD (eds.), Principles of Cloning. San Diego: Elsevier Science; 2002:187-213.
    • (2002) Principles of Cloning , pp. 187-213
    • Gardner, D.K.1    Lane, M.2
  • 4
    • 0015544306 scopus 로고
    • Requirements for the maturation of hamster oocytes in vitro
    • Gwatkin RB, Haidri AA. Requirements for the maturation of hamster oocytes in vitro. Exp Cell Res 1973; 76:1-7.
    • (1973) Exp Cell Res , vol.76 , pp. 1-7
    • Gwatkin, R.B.1    Haidri, A.A.2
  • 5
    • 0022516899 scopus 로고
    • Vitamins and amino acids stimulate hamster blastocysts to hatch in vitro
    • Kane MT, Carney EW, Bavister BD. Vitamins and amino acids stimulate hamster blastocysts to hatch in vitro. J Exp Zool 1986; 239:429-432.
    • (1986) J Exp Zool , vol.239 , pp. 429-432
    • Kane, M.T.1    Carney, E.W.2    Bavister, B.D.3
  • 6
    • 0023356080 scopus 로고
    • Stimulatory and inhibitory effects of amino acids on the development of hamster eight-cell embryos in vitro
    • Carney EW, Bavister BD. Stimulatory and inhibitory effects of amino acids on the development of hamster eight-cell embryos in vitro. J In Vitro Fertil Embryo Transf 1987; 4:162-167.
    • (1987) J In Vitro Fertil Embryo Transf , vol.4 , pp. 162-167
    • Carney, E.W.1    Bavister, B.D.2
  • 7
    • 0024058960 scopus 로고
    • Protein-free culture medium containing polyvinyl alcohol, vitamins, and amino acids supports development of 8-cell hamster embryos to hatching blastocysts
    • Kane MT, Bavister BD. Protein-free culture medium containing polyvinyl alcohol, vitamins, and amino acids supports development of 8-cell hamster embryos to hatching blastocysts. J Exp Zool 1988; 247: 183-187.
    • (1988) J Exp Zool , vol.247 , pp. 183-187
    • Kane, M.T.1    Bavister, B.D.2
  • 8
    • 0025189706 scopus 로고
    • Influence of single amino acids on the development of hamster 1-cell embryos in vitro
    • Bavister BD, Arlotto T. Influence of single amino acids on the development of hamster 1-cell embryos in vitro. Mol Reprod Dev 1990; 25:45-51.
    • (1990) Mol Reprod Dev , vol.25 , pp. 45-51
    • Bavister, B.D.1    Arlotto, T.2
  • 9
    • 0028889774 scopus 로고
    • Analysis of stimulatory and inhibitory amino acids for development of hamster 1-cell embryos in vitro
    • McKiernan SH, Clayton MK, Bavister BD. Analysis of stimulatory and inhibitory amino acids for development of hamster 1-cell embryos in vitro. Mol Reprod Dev 1995; 42:188-199.
    • (1995) Mol Reprod Dev , vol.42 , pp. 188-199
    • McKiernan, S.H.1    Clayton, M.K.2    Bavister, B.D.3
  • 10
    • 0027469082 scopus 로고
    • Amino acids and ammonium regulate mouse embryo development in culture
    • Gardner DK, Lane M. Amino acids and ammonium regulate mouse embryo development in culture. Biol Reprod 1993; 48:377-385.
    • (1993) Biol Reprod , vol.48 , pp. 377-385
    • Gardner, D.K.1    Lane, M.2
  • 11
    • 0028053125 scopus 로고
    • Enhanced rates of cleavage and development for sheep zygotes cultured to the blastocyst stage in vitro in the absence of serum and somatic cells: Amino acids, vitamins, and culturing embryos in groups stimulate development
    • Gardner DK, Lane M, Spitzer A, Batt PA. Enhanced rates of cleavage and development for sheep zygotes cultured to the blastocyst stage in vitro in the absence of serum and somatic cells: amino acids, vitamins, and culturing embryos in groups stimulate development. Biol Reprod 1994; 50:390-400.
    • (1994) Biol Reprod , vol.50 , pp. 390-400
    • Gardner, D.K.1    Lane, M.2    Spitzer, A.3    Batt, P.A.4
  • 12
    • 0028606797 scopus 로고
    • Increase in postimplantation development of cultured mouse embryos by amino acids and induction of fetal retardation and exencephaly by ammonium ions
    • Lane M, Gardner DK. Increase in postimplantation development of cultured mouse embryos by amino acids and induction of fetal retardation and exencephaly by ammonium ions. J Reprod Fertil 1994; 102:305-312.
    • (1994) J Reprod Fertil , vol.102 , pp. 305-312
    • Lane, M.1    Gardner, D.K.2
  • 13
    • 0030455186 scopus 로고    scopus 로고
    • Alleviation of the '2-cell block' and development to the blastocyst of CF1 mouse embryos: Role of amino acids, EDTA and physical parameters
    • Gardner DK, Lane M. Alleviation of the '2-cell block' and development to the blastocyst of CF1 mouse embryos: role of amino acids, EDTA and physical parameters. Hum Reprod 1996; 11:2703-2712.
    • (1996) Hum Reprod , vol.11 , pp. 2703-2712
    • Gardner, D.K.1    Lane, M.2
  • 14
    • 0030880676 scopus 로고    scopus 로고
    • Nonessential amino acids and glutamine decrease the time of the first three cleavage divisions and increase compaction of mouse zygotes in vitro
    • Lane M, Gardner DK. Nonessential amino acids and glutamine decrease the time of the first three cleavage divisions and increase compaction of mouse zygotes in vitro. J Assist Reprod Genet 1997; 14: 398-403.
    • (1997) J Assist Reprod Genet , vol.14 , pp. 398-403
    • Lane, M.1    Gardner, D.K.2
  • 15
    • 0031039706 scopus 로고    scopus 로고
    • Differential regulation of mouse embryo development and viability by amino acids
    • Lane M, Gardner DK. Differential regulation of mouse embryo development and viability by amino acids. J Reprod Fertil 1997; 109: 153-164.
    • (1997) J Reprod Fertil , vol.109 , pp. 153-164
    • Lane, M.1    Gardner, D.K.2
  • 16
    • 0027471711 scopus 로고
    • Mouse embryo cleavage, metabolism and viability: Role of medium composition
    • Gardner DK, Sakkas D. Mouse embryo cleavage, metabolism and viability: role of medium composition. Hum Reprod 1993; 8:288-295.
    • (1993) Hum Reprod , vol.8 , pp. 288-295
    • Gardner, D.K.1    Sakkas, D.2
  • 17
    • 0033920352 scopus 로고    scopus 로고
    • Amino acids and preimplantation development of the mouse in protein-free potassium simplex optimized medium
    • Biggers JD, McGinnis LK, Raffin M. Amino acids and preimplantation development of the mouse in protein-free potassium simplex optimized medium. Biol Reprod 2000; 63:281-293.
    • (2000) Biol Reprod , vol.63 , pp. 281-293
    • Biggers, J.D.1    McGinnis, L.K.2    Raffin, M.3
  • 18
  • 19
    • 0032409174 scopus 로고    scopus 로고
    • Intracellular pH of the mouse preimplantation embryo: Amino acids act as buffers of intracellular pH
    • Edwards LJ, Williams DA, Gardner DK. Intracellular pH of the mouse preimplantation embryo: amino acids act as buffers of intracellular pH. Hum Reprod 1998; 13:3441-3448.
    • (1998) Hum Reprod , vol.13 , pp. 3441-3448
    • Edwards, L.J.1    Williams, D.A.2    Gardner, D.K.3
  • 20
    • 0025278874 scopus 로고
    • Glycine protects pre-implantation mouse conceptuses from a detrimental effect on development of the inorganic ions in oviductal fluid
    • Van Winkle LJ, Haghighat N, Campione AL. Glycine protects pre-implantation mouse conceptuses from a detrimental effect on development of the inorganic ions in oviductal fluid. J Exp Zool 1990; 253: 215-219.
    • (1990) J Exp Zool , vol.253 , pp. 215-219
    • Van Winkle, L.J.1    Haghighat, N.2    Campione, A.L.3
  • 21
    • 0035182391 scopus 로고    scopus 로고
    • Mechanisms for managing cellular and homeostatic stress in vitro
    • Lane M. Mechanisms for managing cellular and homeostatic stress in vitro. Theriogenology 2001; 55:225-236.
    • (2001) Theriogenology , vol.55 , pp. 225-236
    • Lane, M.1
  • 23
    • 0035230411 scopus 로고    scopus 로고
    • Osmoregulation and cell volume regulation in the preimplantation embryo
    • Baltz JM. Osmoregulation and cell volume regulation in the preimplantation embryo. Curr Top Dev Biol 2001; 52:55-106.
    • (2001) Curr Top Dev Biol , vol.52 , pp. 55-106
    • Baltz, J.M.1
  • 24
    • 0026634993 scopus 로고
    • Developmentally related changes in the metabolism of glucose and glutamine by cattle embryos produced and cocultured in vitro
    • Rieger D, Loskutoff NM, Betteridge KJ. Developmentally related changes in the metabolism of glucose and glutamine by cattle embryos produced and cocultured in vitro. J Reprod Fertil 1992; 95:585-595.
    • (1992) J Reprod Fertil , vol.95 , pp. 585-595
    • Rieger, D.1    Loskutoff, N.M.2    Betteridge, K.J.3
  • 25
    • 0000767725 scopus 로고
    • The 2-cell block in CF1 mouse embryos is associated with an increase in glycolysis and a decrease in tricarboxylic acid (TCA) cycle activity: Alleviation of the 2-cell block is associated with the restoration of in vivo metabolic pathway activities
    • Gardner DK, Lane M. The 2-cell block in CF1 mouse embryos is associated with an increase in glycolysis and a decrease in tricarboxylic acid (TCA) cycle activity: alleviation of the 2-cell block is associated with the restoration of in vivo metabolic pathway activities. Biol Reprod 1993; 49(suppl 1):52.
    • (1993) Biol Reprod , vol.49 , Issue.SUPPL. 1 , pp. 52
    • Gardner, D.K.1    Lane, M.2
  • 26
    • 0031810817 scopus 로고    scopus 로고
    • Amino acids and vitamins prevent culture-induced metabolic perturbations and associated loss of viability of mouse blastocysts
    • Lane M, Gardner DK. Amino acids and vitamins prevent culture-induced metabolic perturbations and associated loss of viability of mouse blastocysts. Hum Reprod 1998; 13:991-997.
    • (1998) Hum Reprod , vol.13 , pp. 991-997
    • Lane, M.1    Gardner, D.K.2
  • 27
    • 0015823536 scopus 로고
    • A survey of naturally occurring chelating ligands
    • Lindenbaum A. A survey of naturally occurring chelating ligands. Adv Exp Med Biol 1973; 40:67-77.
    • (1973) Adv Exp Med Biol , vol.40 , pp. 67-77
    • Lindenbaum, A.1
  • 28
    • 0032798552 scopus 로고    scopus 로고
    • Temporal and differential effects of amino acids on bovine embryo development in culture
    • Steeves TE, Gardner DK. Temporal and differential effects of amino acids on bovine embryo development in culture. Biol Reprod 1999; 61:731-740.
    • (1999) Biol Reprod , vol.61 , pp. 731-740
    • Steeves, T.E.1    Gardner, D.K.2
  • 30
    • 0030696589 scopus 로고    scopus 로고
    • Culture and selection of viable blastocysts: A feasible proposition for human IVF?
    • Gardner DK, Lane M. Culture and selection of viable blastocysts: a feasible proposition for human IVF? Hum Reprod Update 1997; 3: 367-382.
    • (1997) Hum Reprod Update , vol.3 , pp. 367-382
    • Gardner, D.K.1    Lane, M.2
  • 31
    • 0032977125 scopus 로고    scopus 로고
    • Preliminary clinical experience with human blastocyst development in vitro without co-culture
    • Behr B, Pool TB, Milki AA, Moore D, Gebhardt J, Dasig D. Preliminary clinical experience with human blastocyst development in vitro without co-culture. Hum Reprod 1999; 14:454-457.
    • (1999) Hum Reprod , vol.14 , pp. 454-457
    • Behr, B.1    Pool, T.B.2    Milki, A.A.3    Moore, D.4    Gebhardt, J.5    Dasig, D.6
  • 32
    • 0034478834 scopus 로고    scopus 로고
    • Embryo nutrition and energy metabolism and its relationship to embryo growth, differentiation, and viability
    • Gardner DK, Pool TB, Lane M. Embryo nutrition and energy metabolism and its relationship to embryo growth, differentiation, and viability. Semin Reprod Med 2000; 18:205-218.
    • (2000) Semin Reprod Med , vol.18 , pp. 205-218
    • Gardner, D.K.1    Pool, T.B.2    Lane, M.3
  • 33
    • 0032422202 scopus 로고    scopus 로고
    • A prospective randomized trial of blastocyst culture and transfer in in-vitro fertilization
    • Gardner DK, Schoolcraft WB, Wagley L, Schlenker T, Stevens J, Hesla J. A prospective randomized trial of blastocyst culture and transfer in in-vitro fertilization. Hum Reprod 1998; 13:3434-3440.
    • (1998) Hum Reprod , vol.13 , pp. 3434-3440
    • Gardner, D.K.1    Schoolcraft, W.B.2    Wagley, L.3    Schlenker, T.4    Stevens, J.5    Hesla, J.6
  • 34
    • 0032459225 scopus 로고    scopus 로고
    • Development of serum-free media for the culture and transfer of human blastocysts
    • Gardner DK. Development of serum-free media for the culture and transfer of human blastocysts. Hum Reprod 1998; 13(suppl 4):218-225.
    • (1998) Hum Reprod , vol.13 , Issue.SUPPL. 4 , pp. 218-225
    • Gardner, D.K.1
  • 35
    • 0026598536 scopus 로고
    • Effect of incubation volume and embryo density on the development and viability of mouse embryos in vitro
    • Lane M, Gardner DK. Effect of incubation volume and embryo density on the development and viability of mouse embryos in vitro. Hum Reprod 1992; 7:558-562.
    • (1992) Hum Reprod , vol.7 , pp. 558-562
    • Lane, M.1    Gardner, D.K.2
  • 36
    • 0024389675 scopus 로고
    • The human blastocyst: Cell number, death and allocation during late preimplantation development in vitro
    • Hardy K, Handyside AH, Winston RM. The human blastocyst: cell number, death and allocation during late preimplantation development in vitro. Development 1989; 107:597-604.
    • (1989) Development , vol.107 , pp. 597-604
    • Hardy, K.1    Handyside, A.H.2    Winston, R.M.3
  • 37
    • 0033780350 scopus 로고    scopus 로고
    • EDTA stimulates cleavage stage bovine embryo development in culture but inhibits blastocyst development and differentiation
    • Gardner DK, Lane MW, Lane M. EDTA stimulates cleavage stage bovine embryo development in culture but inhibits blastocyst development and differentiation. Mol Reprod Dev 2000; 57:256-261.
    • (2000) Mol Reprod Dev , vol.57 , pp. 256-261
    • Gardner, D.K.1    Lane, M.W.2    Lane, M.3
  • 38
    • 0036356227 scopus 로고    scopus 로고
    • Apoptosis in the preimplantation mouse embryo: Effect of strain difference and in vitro culture
    • Kamjoo M, Brison DR, Kimber SJ. Apoptosis in the preimplantation mouse embryo: effect of strain difference and in vitro culture. Mol Reprod Dev 2002; 61:67-77.
    • (2002) Mol Reprod Dev , vol.61 , pp. 67-77
    • Kamjoo, M.1    Brison, D.R.2    Kimber, S.J.3
  • 39
    • 0033981528 scopus 로고    scopus 로고
    • Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo
    • Lane M, Gardner DK. Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo. Biol Reprod 2000; 62: 16-22.
    • (2000) Biol Reprod , vol.62 , pp. 16-22
    • Lane, M.1    Gardner, D.K.2
  • 40
    • 0029805367 scopus 로고    scopus 로고
    • Bicarbonate/chloride exchange and intracellular pH throughout preimplantation mouse embryo development
    • Zhao Y, Baltz JM. Bicarbonate/chloride exchange and intracellular pH throughout preimplantation mouse embryo development. Am J Physiol 1996; 271:C1512-C1520.
    • (1996) Am J Physiol , vol.271
    • Zhao, Y.1    Baltz, J.M.2
  • 41
    • 0033120151 scopus 로고    scopus 로고
    • + antiporter activity in hamster embryos is activated during fertilization
    • + antiporter activity in hamster embryos is activated during fertilization. Dev Biol 1999; 208:244-252.
    • (1999) Dev Biol , vol.208 , pp. 244-252
    • Lane, M.1    Baltz, J.M.2    Bavister, B.D.3
  • 43
    • 0017693935 scopus 로고
    • Application of a morphological time scale to hereditary differences in prenatal mouse development
    • Wahlsten D, Wainwright P. Application of a morphological time scale to hereditary differences in prenatal mouse development. J Embryol Exp Morphol 1977; 42:79-92.
    • (1977) J Embryol Exp Morphol , vol.42 , pp. 79-92
    • Wahlsten, D.1    Wainwright, P.2
  • 44
    • 0034793005 scopus 로고    scopus 로고
    • Effect of essential amino acids on mouse embryo viability and ammonium production
    • Lane M, Hooper K, Gardner DK. Effect of essential amino acids on mouse embryo viability and ammonium production. J Assist Reprod Genet 2001; 18:519-525.
    • (2001) J Assist Reprod Genet , vol.18 , pp. 519-525
    • Lane, M.1    Hooper, K.2    Gardner, D.K.3
  • 45
    • 0020070864 scopus 로고
    • Quantitative changes in total RNA, total poly(A), and ribosomes in early mouse embryos
    • Piko L, Clegg KB. Quantitative changes in total RNA, total poly(A), and ribosomes in early mouse embryos. Dev Biol 1982; 89:362-378.
    • (1982) Dev Biol , vol.89 , pp. 362-378
    • Piko, L.1    Clegg, K.B.2
  • 46
    • 0028997958 scopus 로고
    • Preimplantation development of mouse embryos in KSOM: Augmentation by amino acids and analysis of gene expression
    • Ho Y, Wigglesworth K, Eppig JJ, Schultz RM. Preimplantation development of mouse embryos in KSOM: augmentation by amino acids and analysis of gene expression. Mol Reprod Dev 1995; 41:232-238.
    • (1995) Mol Reprod Dev , vol.41 , pp. 232-238
    • Ho, Y.1    Wigglesworth, K.2    Eppig, J.J.3    Schultz, R.M.4
  • 48
    • 0034796209 scopus 로고    scopus 로고
    • Fetal exencephaly arising as a result of preimplantation exposure to ammonium chloride
    • Sinawat S. Fetal exencephaly arising as a result of preimplantation exposure to ammonium chloride. J Med Assoc Thai 2001; 84:821-830.
    • (2001) J Med Assoc Thai , vol.84 , pp. 821-830
    • Sinawat, S.1
  • 49
    • 0030885435 scopus 로고    scopus 로고
    • Effects of glutamine and taurine on preimplantation development and cleavage of mouse embryos in vitro
    • Devreker F, Hardy K. Effects of glutamine and taurine on preimplantation development and cleavage of mouse embryos in vitro. Biol Reprod 1997; 57:921-928.
    • (1997) Biol Reprod , vol.57 , pp. 921-928
    • Devreker, F.1    Hardy, K.2
  • 50
    • 0026362774 scopus 로고
    • Metabolism of the preimplantation mammalian embryo
    • Leese HJ. Metabolism of the preimplantation mammalian embryo. Oxf Rev Reprod Biol 1991; 13:35-72.
    • (1991) Oxf Rev Reprod Biol , vol.13 , pp. 35-72
    • Leese, H.J.1
  • 51
    • 0022617168 scopus 로고
    • Noninvasive measurement of nutrient uptake by single cultured preimplantation mouse embryos
    • Gardner DK, Leese HJ. Noninvasive measurement of nutrient uptake by single cultured preimplantation mouse embryos. Hum Reprod 1986; 1:25-27.
    • (1986) Hum Reprod , vol.1 , pp. 25-27
    • Gardner, D.K.1    Leese, H.J.2
  • 52
    • 0024512816 scopus 로고
    • Noninvasive measurement of glucose and pyruvate uptake by individual human oocytes and preimplantation embryos
    • Hardy K, Hooper MA, Handyside AH, Rutherford AJ, Winston RM, Leese HJ. Noninvasive measurement of glucose and pyruvate uptake by individual human oocytes and preimplantation embryos. Hum Reprod 1989; 4:188-191.
    • (1989) Hum Reprod , vol.4 , pp. 188-191
    • Hardy, K.1    Hooper, M.A.2    Handyside, A.H.3    Rutherford, A.J.4    Winston, R.M.5    Leese, H.J.6
  • 53
    • 0025346983 scopus 로고
    • Non-invasive measurement of pyruvate and glucose uptake and lactate production by single human preimplantation embryos
    • Gott AL, Hardy K, Winston RM, Leese HJ. Non-invasive measurement of pyruvate and glucose uptake and lactate production by single human preimplantation embryos. Hum Reprod 1990; 5:104-108.
    • (1990) Hum Reprod , vol.5 , pp. 104-108
    • Gott, A.L.1    Hardy, K.2    Winston, R.M.3    Leese, H.J.4
  • 54
    • 0027442748 scopus 로고
    • Uptake and metabolism of pyruvate and glucose by individual sheep preattachment embryos developed in vivo
    • Gardner DK, Lane M, Batt P. Uptake and metabolism of pyruvate and glucose by individual sheep preattachment embryos developed in vivo. Mol Reprod Dev 1993; 36:313-319.
    • (1993) Mol Reprod Dev , vol.36 , pp. 313-319
    • Gardner, D.K.1    Lane, M.2    Batt, P.3
  • 55
    • 0025993329 scopus 로고
    • Glucose and phosphate inhibit respiration and oxidative metabolism in cultured hamster 8-cell embryos: Evidence for the crabtree effect
    • Seshagiri PB, Bavister BD. Glucose and phosphate inhibit respiration and oxidative metabolism in cultured hamster 8-cell embryos: evidence for the crabtree effect. Mol Reprod Dev 1991; 30:105-111.
    • (1991) Mol Reprod Dev , vol.30 , pp. 105-111
    • Seshagiri, P.B.1    Bavister, B.D.2
  • 56
    • 0024353339 scopus 로고
    • Differential effects of ammonia and β-methylene-DL-aspartate on metabolism of glutamate and related amino acids by astrocytes and neurons in primary culture
    • Lai JC, Murthy CR, Cooper AJ, Hertz E, Hertz L. Differential effects of ammonia and β-methylene-DL-aspartate on metabolism of glutamate and related amino acids by astrocytes and neurons in primary culture. Neurochem Res 1989; 14:377-389.
    • (1989) Neurochem Res , vol.14 , pp. 377-389
    • Lai, J.C.1    Murthy, C.R.2    Cooper, A.J.3    Hertz, E.4    Hertz, L.5
  • 57
    • 0026350138 scopus 로고
    • Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: Effects of in vitro treatment with ammonia, hyperammonemia and hepatic encephalopathy
    • Faff-Michalak L, Albrecht J. Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: effects of in vitro treatment with ammonia, hyperammonemia and hepatic encephalopathy. Metab Brain Dis 1991; 6:187-197.
    • (1991) Metab Brain Dis , vol.6 , pp. 187-197
    • Faff-Michalak, L.1    Albrecht, J.2
  • 58
    • 0023710552 scopus 로고
    • Effects of ammonia and β-methylene-DL-aspartate on the oxidation of glucose and pyruvate by neurons and astrocytes in primary culture
    • Fitzpatrick SM, Cooper AJ, Hertz L. Effects of ammonia and β-methylene-DL-aspartate on the oxidation of glucose and pyruvate by neurons and astrocytes in primary culture. J Neurochem 1988; 51:1197-1203.
    • (1988) J Neurochem , vol.51 , pp. 1197-1203
    • Fitzpatrick, S.M.1    Cooper, A.J.2    Hertz, L.3
  • 59
    • 0023281974 scopus 로고
    • Cerebral ammonia metabolism in normal and hyperammonemic rats
    • Cooper AJ, Lai JC. Cerebral ammonia metabolism in normal and hyperammonemic rats. Neurochem Pathol 1987; 6:67-95.
    • (1987) Neurochem Pathol , vol.6 , pp. 67-95
    • Cooper, A.J.1    Lai, J.C.2
  • 60
    • 0000278851 scopus 로고    scopus 로고
    • Regulation of substrate utilization in mouse embryos by the malate-aspartate shuttle
    • Lane M, Gardner DK. Regulation of substrate utilization in mouse embryos by the malate-aspartate shuttle. Biol Reprod 2000; 62(suppl 1):371.
    • (2000) Biol Reprod , vol.62 , Issue.SUPPL. 1 , pp. 371
    • Lane, M.1    Gardner, D.K.2
  • 62
    • 0032799053 scopus 로고    scopus 로고
    • Bicarbonate/chloride exchange regulates intracellular pH of embryos but not oocytes of the hamster
    • Lane M, Baltz JM, Bavister BD. Bicarbonate/chloride exchange regulates intracellular pH of embryos but not oocytes of the hamster. Biol Reprod 1999; 61:452-457.
    • (1999) Biol Reprod , vol.61 , pp. 452-457
    • Lane, M.1    Baltz, J.M.2    Bavister, B.D.3
  • 63
    • 0034112603 scopus 로고    scopus 로고
    • Differential effects of culture on imprinted H19 expression in the pre-implantation mouse embryo
    • Doherty AS, Mann MR, Tremblay KD, Bartolomei MS, Schultz RM. Differential effects of culture on imprinted H19 expression in the pre-implantation mouse embryo. Biol Reprod 2000; 62:1526-1535.
    • (2000) Biol Reprod , vol.62 , pp. 1526-1535
    • Doherty, A.S.1    Mann, M.R.2    Tremblay, K.D.3    Bartolomei, M.S.4    Schultz, R.M.5
  • 64
    • 0037883058 scopus 로고    scopus 로고
    • In vivo rates of mouse embryo development can be attained in vitro
    • Reed LJ, Lane M, Gardner DK. In vivo rates of mouse embryo development can be attained in vitro. Theriogenology 2003; 59:349.
    • (2003) Theriogenology , vol.59 , pp. 349
    • Reed, L.J.1    Lane, M.2    Gardner, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.