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Volumn 85, Issue 5, 2006, Pages 1319-1340

Obesity and androgens: facts and perspectives

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANTIANDROGEN; BIOFUEL; CYPROTERONE ACETATE; DROSPIRENONE; ENZYME; ESTROGEN; FINASTERIDE; FLUTAMIDE; GESTODENE; GHRELIN; GONADORELIN AGONIST; GONADOTROPIN; LEPTIN; METFORMIN; ORAL CONTRACEPTIVE AGENT; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; SPIRONOLACTONE; TESTOSTERONE;

EID: 33646110761     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2005.10.054     Document Type: Article
Times cited : (362)

References (223)
  • 2
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn B.B., and Flier J.S. Obesity and insulin resistance. J Clin Invest 106 (2000) 473-481
    • (2000) J Clin Invest , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 3
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue. their relation to the metabolic syndrome
    • Wajchenberg B.L. Subcutaneous and visceral adipose tissue. their relation to the metabolic syndrome. Endocr Rev 21 (2000) 697-738
    • (2000) Endocr Rev , vol.21 , pp. 697-738
    • Wajchenberg, B.L.1
  • 4
    • 0011970705 scopus 로고    scopus 로고
    • Obesity and hormonal abnormalities
    • Bjorntorp P. (Ed), John Wiley & Sons, Chichester (UK)
    • Pasquali R., and Vicennati V. Obesity and hormonal abnormalities. In: Bjorntorp P. (Ed). International textbook of obesity (2001), John Wiley & Sons, Chichester (UK) 225-239
    • (2001) International textbook of obesity , pp. 225-239
    • Pasquali, R.1    Vicennati, V.2
  • 6
    • 0037396460 scopus 로고    scopus 로고
    • Androgens and coronary artery disease
    • Hu F.C.W., and von Eckardstein A. Androgens and coronary artery disease. Endocr Rev 24 (2003) 183-217
    • (2003) Endocr Rev , vol.24 , pp. 183-217
    • Hu, F.C.W.1    von Eckardstein, A.2
  • 7
    • 0024538169 scopus 로고
    • On the regulation of sex-hormone-binding globulin. A challenge of old dogma and outlines of an alternative mechanism
    • Von Shoultz B., and Carlstrom K. On the regulation of sex-hormone-binding globulin. A challenge of old dogma and outlines of an alternative mechanism. J Steroid Biochem 32 (1989) 327-334
    • (1989) J Steroid Biochem , vol.32 , pp. 327-334
    • Von Shoultz, B.1    Carlstrom, K.2
  • 8
    • 0034474076 scopus 로고    scopus 로고
    • Sex steroid hormones, sex hormone-binding globulin, and obesity in men and women
    • Tchernof A., and Despres J.P. Sex steroid hormones, sex hormone-binding globulin, and obesity in men and women. Horm Metab Res 32 (2000) 526-536
    • (2000) Horm Metab Res , vol.32 , pp. 526-536
    • Tchernof, A.1    Despres, J.P.2
  • 9
    • 0025240105 scopus 로고
    • Characterization of obese women with reduced sex hormone-binding globulin concentrations
    • Pasquali R., Casimirri F., Platé L., and Capelli M. Characterization of obese women with reduced sex hormone-binding globulin concentrations. Horm Metab Res 22 (1990) 303-306
    • (1990) Horm Metab Res , vol.22 , pp. 303-306
    • Pasquali, R.1    Casimirri, F.2    Platé, L.3    Capelli, M.4
  • 10
    • 0020563854 scopus 로고
    • Relationship of androgenic activity to body fat topography, fat cell morphology and metabolic aberrations in premenopausal women
    • Evans D.J., Hoffmann R.G., Kalkhoff R.K., and Kissebah A.H. Relationship of androgenic activity to body fat topography, fat cell morphology and metabolic aberrations in premenopausal women. J Clin Endocrinol Metab 57 (1983) 304-310
    • (1983) J Clin Endocrinol Metab , vol.57 , pp. 304-310
    • Evans, D.J.1    Hoffmann, R.G.2    Kalkhoff, R.K.3    Kissebah, A.H.4
  • 13
    • 0023181204 scopus 로고
    • Maintenance of normal circulating levels of Δ4-androstenedine and dehydroepiandrosterone in simple obesity despite increased metabolic clearance rates. evidence for a servo-control mechanism
    • Kurtz B.R., Givens J.R., Komindrr S., Stevens M.D., Karas J.G., Bittle J.B., et al. Maintenance of normal circulating levels of Δ4-androstenedine and dehydroepiandrosterone in simple obesity despite increased metabolic clearance rates. evidence for a servo-control mechanism. J Clin Endocrinol Metab 64 (1987) 1261-1267
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 1261-1267
    • Kurtz, B.R.1    Givens, J.R.2    Komindrr, S.3    Stevens, M.D.4    Karas, J.G.5    Bittle, J.B.6
  • 14
    • 0030460782 scopus 로고    scopus 로고
    • The endocrinology of obesity
    • Smith S.R. The endocrinology of obesity. Endocr Metab Clin North Am 25 (1996) 921-942
    • (1996) Endocr Metab Clin North Am , vol.25 , pp. 921-942
    • Smith, S.R.1
  • 15
    • 0025050724 scopus 로고
    • Plasma free and nonsex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity
    • Zumoff B., Strain G., Miller L.K., Rosner W., Senie R., Seres D., et al. Plasma free and nonsex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity. J Clin Endocrinol Metab 71 (1990) 929-931
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 929-931
    • Zumoff, B.1    Strain, G.2    Miller, L.K.3    Rosner, W.4    Senie, R.5    Seres, D.6
  • 19
    • 0027210856 scopus 로고
    • Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men
    • Vermeulen A., Kaufman J.M., Deslypere J.P., and Thomas G. Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men. J Clin Endocrinol Metab 76 (1993) 1140-1146
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1140-1146
    • Vermeulen, A.1    Kaufman, J.M.2    Deslypere, J.P.3    Thomas, G.4
  • 20
    • 0027520830 scopus 로고
    • Origin and significance of plasma androsterone glucuronide levels. a parameter of adrenal androgen secretion and hepatic 5 alpha-reductase activity
    • Giagulli Giagulli V.A., Giorgino R., and Vermeulen A. Origin and significance of plasma androsterone glucuronide levels. a parameter of adrenal androgen secretion and hepatic 5 alpha-reductase activity. J Clin Endocrinol Metab 76 (1993) 918-923
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 918-923
    • Giagulli Giagulli, V.A.1    Giorgino, R.2    Vermeulen, A.3
  • 21
    • 0026761599 scopus 로고
    • Lower endogenous androgens predict central adiposity in men
    • Khaw K.T., and Barrett-Connor E. Lower endogenous androgens predict central adiposity in men. Ann Epidemiol 2 (1992) 675-682
    • (1992) Ann Epidemiol , vol.2 , pp. 675-682
    • Khaw, K.T.1    Barrett-Connor, E.2
  • 23
    • 84995867052 scopus 로고
    • Visceral fat accumulation in relation to sex hormones in obese men and women undergoing weight loss therapy
    • Leenen R., van der Koy K., Seidell J.C., Deurenberg P., and Kopperschaar H.P.F. Visceral fat accumulation in relation to sex hormones in obese men and women undergoing weight loss therapy. J Clin Endocrinol Metab 78 (1994) 1515-1520
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1515-1520
    • Leenen, R.1    van der Koy, K.2    Seidell, J.C.3    Deurenberg, P.4    Kopperschaar, H.P.F.5
  • 24
    • 0023809454 scopus 로고
    • Inhibition of sex hormone-binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactin
    • Plymate S.R., Matej L.A., Jones R.E., and Friedl K.E. Inhibition of sex hormone-binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactin. J Clin Endocrinol Metab 67 (1988) 460-464
    • (1988) J Clin Endocrinol Metab , vol.67 , pp. 460-464
    • Plymate, S.R.1    Matej, L.A.2    Jones, R.E.3    Friedl, K.E.4
  • 25
    • 0033304934 scopus 로고    scopus 로고
    • The insulin-related ovarian regulatory system in health and disease
    • Poretsky L., Cataldo N.A., Rosenwaks Z., and Giudice L.C. The insulin-related ovarian regulatory system in health and disease. Endocr Rev 20 (1999) 535-582
    • (1999) Endocr Rev , vol.20 , pp. 535-582
    • Poretsky, L.1    Cataldo, N.A.2    Rosenwaks, Z.3    Giudice, L.C.4
  • 27
    • 0028894345 scopus 로고
    • Insulin regulates testosterone and sex hormone-binding globulin concentrations in adult normal weight and obese men
    • Pasquali R., Casimirri F., De Iasio R., Mesini P., Boschi S., Chierici R., et al. Insulin regulates testosterone and sex hormone-binding globulin concentrations in adult normal weight and obese men. J Clin Endocrinol Metab 80 (1995) 654-658
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 654-658
    • Pasquali, R.1    Casimirri, F.2    De Iasio, R.3    Mesini, P.4    Boschi, S.5    Chierici, R.6
  • 28
    • 18844362098 scopus 로고    scopus 로고
    • Increasing insulin resistance is associated with a decrease in leydig cell testosterone secretion in men
    • Pitteloud N., Hardin M., Dwyer A.A., Valassi E., Yialamas M., Elahi D., et al. Increasing insulin resistance is associated with a decrease in leydig cell testosterone secretion in men. J Clin Endocrinol Metab 90 (2005) 2636-2641
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2636-2641
    • Pitteloud, N.1    Hardin, M.2    Dwyer, A.A.3    Valassi, E.4    Yialamas, M.5    Elahi, D.6
  • 29
    • 0000840138 scopus 로고
    • Role of extraglandular estrogen in goman endocrinology
    • Greep P.O., and Astwood E. (Eds), American Physiological Society, Washington (DC) Handbook of physiology. Sect. 7: Endocrinology. Vol. 11
    • Siiteri P.K., and McDonald P.C. Role of extraglandular estrogen in goman endocrinology. In: Greep P.O., and Astwood E. (Eds). Female reproduction system (1973), American Physiological Society, Washington (DC) 615 Handbook of physiology. Sect. 7: Endocrinology. Vol. 11
    • (1973) Female reproduction system , pp. 615
    • Siiteri, P.K.1    McDonald, P.C.2
  • 31
    • 0003128718 scopus 로고
    • Functional aberrations of the hypothalamic-pituitary system in polycystic ovary. A consideration of the pathogenesis
    • James W.H.T., Serio M., and Giusti G. (Eds), Academic Press, New York
    • Yen S.S.C., Chaney C., and Judd H.L. Functional aberrations of the hypothalamic-pituitary system in polycystic ovary. A consideration of the pathogenesis. In: James W.H.T., Serio M., and Giusti G. (Eds). The endocrine function of the human ovary (1976), Academic Press, New York 373-380
    • (1976) The endocrine function of the human ovary , pp. 373-380
    • Yen, S.S.C.1    Chaney, C.2    Judd, H.L.3
  • 32
    • 0023864662 scopus 로고
    • Pathogenesis and treatment of polycystic ovary syndrome
    • McKenna T.J. Pathogenesis and treatment of polycystic ovary syndrome. N Engl J Med 318 (1988) 558-562
    • (1988) N Engl J Med , vol.318 , pp. 558-562
    • McKenna, T.J.1
  • 33
    • 0014629578 scopus 로고
    • Conversion of blood androgens to estrogens in normal adult men and women
    • Longcope C., Kato T., and Horton R. Conversion of blood androgens to estrogens in normal adult men and women. J Clin Invest 48 (1969) 2191-2201
    • (1969) J Clin Invest , vol.48 , pp. 2191-2201
    • Longcope, C.1    Kato, T.2    Horton, R.3
  • 34
    • 0024505275 scopus 로고
    • Endocrine aspects of obesity
    • Glass A.R. Endocrine aspects of obesity. Endocr Metab Clin North Am 73 (1989) 139-160
    • (1989) Endocr Metab Clin North Am , vol.73 , pp. 139-160
    • Glass, A.R.1
  • 36
    • 0023915573 scopus 로고
    • Effect of massive weight loss on hypothalamic-pituitary-gonadal function in obese men
    • Strain G.W., Zumoff B., Miller L.K., et al. Effect of massive weight loss on hypothalamic-pituitary-gonadal function in obese men. J Clin Endocrinol Metab 66 (1988) 1019-1023
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 1019-1023
    • Strain, G.W.1    Zumoff, B.2    Miller, L.K.3
  • 39
    • 0141570989 scopus 로고    scopus 로고
    • Reversal of the hypogonadotropic hypogonadism of obese men by administration of the aromatase inhibitor testolactone
    • Zumoff B., Miller L.K., and Strain G.W. Reversal of the hypogonadotropic hypogonadism of obese men by administration of the aromatase inhibitor testolactone. Metabolism 52 (1999) 1126-1128
    • (1999) Metabolism , vol.52 , pp. 1126-1128
    • Zumoff, B.1    Miller, L.K.2    Strain, G.W.3
  • 40
    • 0021746013 scopus 로고
    • Impaired growth hormone response to growth hormone releasing factor in obesity. a pituitary defect reversed with weight reduction
    • Williams T., Berelowitz M., Joffe S.N., Thorner M.O., Rivier J., Vale W., et al. Impaired growth hormone response to growth hormone releasing factor in obesity. a pituitary defect reversed with weight reduction. N Engl J Med 311 (1984) 1403-1407
    • (1984) N Engl J Med , vol.311 , pp. 1403-1407
    • Williams, T.1    Berelowitz, M.2    Joffe, S.N.3    Thorner, M.O.4    Rivier, J.5    Vale, W.6
  • 41
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice. what have we learned and where they lead us?
    • Couse J.F., and Korach K.H. Estrogen receptor null mice. what have we learned and where they lead us?. Endocr Rev 20 (1999) 358-417
    • (1999) Endocr Rev , vol.20 , pp. 358-417
    • Couse, J.F.1    Korach, K.H.2
  • 42
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
    • Smith E.P., Boyd J., Frank G.R., Takasashi H., Cohen R.M., Specker B., et al. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 331 (1994) 1056-1061
    • (1994) N Engl J Med , vol.331 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank, G.R.3    Takasashi, H.4    Cohen, R.M.5    Specker, B.6
  • 44
    • 77957126077 scopus 로고    scopus 로고
    • Effect of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopaual women
    • The Writing Group for the PEPI Trial
    • The Writing Group for the PEPI Trial. Effect of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopaual women. JAMA 273 (1996) 199-208
    • (1996) JAMA , vol.273 , pp. 199-208
  • 45
    • 0037302039 scopus 로고    scopus 로고
    • Hormone replacement therapy dissociates fat mass and bone mass, and tends to reduce weight gain in early postmenopausal women. a randomized controlled 5-year clinical trial of the Danish Osteoporosis Prevention Study
    • Jensen L.B., Vestergaard P., Hermann A.P., Gram J., Eiken P., Abrahamsen B., et al. Hormone replacement therapy dissociates fat mass and bone mass, and tends to reduce weight gain in early postmenopausal women. a randomized controlled 5-year clinical trial of the Danish Osteoporosis Prevention Study. J Bone Miner Res 18 (2003) 333-342
    • (2003) J Bone Miner Res , vol.18 , pp. 333-342
    • Jensen, L.B.1    Vestergaard, P.2    Hermann, A.P.3    Gram, J.4    Eiken, P.5    Abrahamsen, B.6
  • 49
    • 0029972402 scopus 로고    scopus 로고
    • The regulation of adipose tissue distribution in humans
    • Bjorntorp P. The regulation of adipose tissue distribution in humans. Int J Obes 20 (1996) 291-302
    • (1996) Int J Obes , vol.20 , pp. 291-302
    • Bjorntorp, P.1
  • 50
    • 0034473226 scopus 로고    scopus 로고
    • The abdominal obesity phenotype and insulin resistance are associated with abnormalities of the hypothalamic-pituitary-adrenal axis in humans
    • Pasquali R., and Vicennati V. The abdominal obesity phenotype and insulin resistance are associated with abnormalities of the hypothalamic-pituitary-adrenal axis in humans. Horm Metab Res 32 (2000) 521-525
    • (2000) Horm Metab Res , vol.32 , pp. 521-525
    • Pasquali, R.1    Vicennati, V.2
  • 51
    • 0002803873 scopus 로고    scopus 로고
    • Centralization of body fat
    • Bjorntorp P. (Ed), John Wiley & Sons, Chichester (UK)
    • Bjorntorp P. Centralization of body fat. In: Bjorntorp P. (Ed). International textbook of obesity (2001), John Wiley & Sons, Chichester (UK) 213-224
    • (2001) International textbook of obesity , pp. 213-224
    • Bjorntorp, P.1
  • 53
    • 0035656177 scopus 로고    scopus 로고
    • Pathophysiology of modulation of local glucocorticoid levels by11 β -hydroxysteroid dehydrogenase
    • Sandeep T.C., and Walker B.R. Pathophysiology of modulation of local glucocorticoid levels by11 β -hydroxysteroid dehydrogenase. Trends Endocrinol Metab 12 (2001) 446-453
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 446-453
    • Sandeep, T.C.1    Walker, B.R.2
  • 54
    • 4043077286 scopus 로고    scopus 로고
    • 11β-hydroxysteroid dehydrogenase type 1. a tissue specific regulation of glucorticoid response
    • Tomlinson J.W., Walker E.A., Bujalska I.J., Draper N., Lavery G.G., Cooper M.S., et al. 11β-hydroxysteroid dehydrogenase type 1. a tissue specific regulation of glucorticoid response. Endocr Rev 25 (2004) 831-866
    • (2004) Endocr Rev , vol.25 , pp. 831-866
    • Tomlinson, J.W.1    Walker, E.A.2    Bujalska, I.J.3    Draper, N.4    Lavery, G.G.5    Cooper, M.S.6
  • 56
    • 0034024622 scopus 로고    scopus 로고
    • Effects of stress on reproduction in nonrodent mammals. the role of glucocorticoids and sex differences
    • Tilbrook A.J., Turner A.I., and Clarke I.J. Effects of stress on reproduction in nonrodent mammals. the role of glucocorticoids and sex differences. Rev Reprod 5 (2000) 105-113
    • (2000) Rev Reprod , vol.5 , pp. 105-113
    • Tilbrook, A.J.1    Turner, A.I.2    Clarke, I.J.3
  • 57
    • 0028577497 scopus 로고
    • Gonadal steroid hormone receptors and sex differences in the hypothalamo-pituitary-adrenal axis
    • Handa R.J., Burgess L.H., Kerr J.E., and O'Keefe J.A. Gonadal steroid hormone receptors and sex differences in the hypothalamo-pituitary-adrenal axis. Horm Behav 28 (1994) 464-476
    • (1994) Horm Behav , vol.28 , pp. 464-476
    • Handa, R.J.1    Burgess, L.H.2    Kerr, J.E.3    O'Keefe, J.A.4
  • 58
    • 0029960048 scopus 로고    scopus 로고
    • The inhibitory effect of testosterone on hypothalamic-pituitary-adrenal responses to stress is mediated by the medial preoptic area
    • Viau V., and Meaney M.J. The inhibitory effect of testosterone on hypothalamic-pituitary-adrenal responses to stress is mediated by the medial preoptic area. J Neurosci 16 (1996) 1866-1876
    • (1996) J Neurosci , vol.16 , pp. 1866-1876
    • Viau, V.1    Meaney, M.J.2
  • 59
    • 0036113817 scopus 로고    scopus 로고
    • Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes
    • Viau V. Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes. J Neuroendocrinol 14 (2002) 506-513
    • (2002) J Neuroendocrinol , vol.14 , pp. 506-513
    • Viau, V.1
  • 60
    • 0029011866 scopus 로고
    • Effects of age and gender on pituitary-adrenocortical responsiveness in humans
    • Born J., Ditschuneit I., Schreiber M., Dodt C., and Fehm H.L. Effects of age and gender on pituitary-adrenocortical responsiveness in humans. Eur J Endocrinol 132 (1995) 705-711
    • (1995) Eur J Endocrinol , vol.132 , pp. 705-711
    • Born, J.1    Ditschuneit, I.2    Schreiber, M.3    Dodt, C.4    Fehm, H.L.5
  • 61
    • 0033974740 scopus 로고    scopus 로고
    • Production rates of testosterone in patients with Cushing's syndrome
    • Vierhapper H., Nowotny P., and Waldhausl W. Production rates of testosterone in patients with Cushing's syndrome. Metabolism 49 (2000) 229-231
    • (2000) Metabolism , vol.49 , pp. 229-231
    • Vierhapper, H.1    Nowotny, P.2    Waldhausl, W.3
  • 62
    • 0031773511 scopus 로고    scopus 로고
    • Menstrual abnormalities in women with Cushing's disease are correlated with hypercortisolemia rather than raised circulating androgen levels
    • Lado-Abeal J., Rodriguez-Arnao J., Newell-Price J.D., Perry L.A., Grossman A.B., Besser G.M., et al. Menstrual abnormalities in women with Cushing's disease are correlated with hypercortisolemia rather than raised circulating androgen levels. J Clin Endocrinol Metab 83 (1998) 3083-3088
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3083-3088
    • Lado-Abeal, J.1    Rodriguez-Arnao, J.2    Newell-Price, J.D.3    Perry, L.A.4    Grossman, A.B.5    Besser, G.M.6
  • 63
    • 33646119608 scopus 로고    scopus 로고
    • Sex difference in the relationship between the hypothalamic-pituitary-adrenal (HPA) axis and sex hormones in obesity
    • Vicennati V., Ceroni L., Genghini S., Patton L., Pagotto U., and Pasquali R. Sex difference in the relationship between the hypothalamic-pituitary-adrenal (HPA) axis and sex hormones in obesity. Obes Res 14 (2006)
    • (2006) Obes Res , vol.14
    • Vicennati, V.1    Ceroni, L.2    Genghini, S.3    Patton, L.4    Pagotto, U.5    Pasquali, R.6
  • 65
    • 0031767057 scopus 로고    scopus 로고
    • Leptin. in search for role(s) in human physiology and pathophysiology
    • Mantzoros C.S., and Moschos S. Leptin. in search for role(s) in human physiology and pathophysiology. Clin Endocrinol (Oxf) 49 (1998) 551-567
    • (1998) Clin Endocrinol (Oxf) , vol.49 , pp. 551-567
    • Mantzoros, C.S.1    Moschos, S.2
  • 66
    • 0348107406 scopus 로고    scopus 로고
    • Regulation of adipocytokines and insulin resistance
    • Fasshauer M., and Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia 46 (2003) 1594-1603
    • (2003) Diabetologia , vol.46 , pp. 1594-1603
    • Fasshauer, M.1    Paschke, R.2
  • 68
    • 0031054698 scopus 로고    scopus 로고
    • Depot- and sex specific differences in human leptin mRNA expression. implications for the control of regional fat distribution
    • Montague C.T., Prins J.B., Sanders l., Digby J.E., and O'Rahilly S. Depot- and sex specific differences in human leptin mRNA expression. implications for the control of regional fat distribution. Diabetes 46 (1997) 342-347
    • (1997) Diabetes , vol.46 , pp. 342-347
    • Montague, C.T.1    Prins, J.B.2    Sanders, l.3    Digby, J.E.4    O'Rahilly, S.5
  • 69
    • 0036205363 scopus 로고    scopus 로고
    • Circulating concentrations of soluble leptin receptor. influence of menstrual cycle and diet
    • Shimizu H., Shimomura K., Negishi M., Masumago M., Uehara Y., Sato N., et al. Circulating concentrations of soluble leptin receptor. influence of menstrual cycle and diet. Nutrition 18 (2002) 309-312
    • (2002) Nutrition , vol.18 , pp. 309-312
    • Shimizu, H.1    Shimomura, K.2    Negishi, M.3    Masumago, M.4    Uehara, Y.5    Sato, N.6
  • 70
    • 0033822726 scopus 로고    scopus 로고
    • Differences in circulating concentrations of total, free and bound leptin relate to gender and body composition in adult humans
    • McConway M.G., Johnson D., Kelly A., Griffin D., Smith J., and Wallace A.M. Differences in circulating concentrations of total, free and bound leptin relate to gender and body composition in adult humans. Ann Clin Biochem 37 (2000) 717-723
    • (2000) Ann Clin Biochem , vol.37 , pp. 717-723
    • McConway, M.G.1    Johnson, D.2    Kelly, A.3    Griffin, D.4    Smith, J.5    Wallace, A.M.6
  • 71
    • 0029907970 scopus 로고    scopus 로고
    • Evidence for leptin binding to proteins in serum of rodents and humans. modulation with obesity
    • Housecknecht K.L., Mantzoros C.S., Kuliawat R., Hadro E., Flier J.S., and Kahn B.B. Evidence for leptin binding to proteins in serum of rodents and humans. modulation with obesity. Diabetes 45 (1996) 1638-1643
    • (1996) Diabetes , vol.45 , pp. 1638-1643
    • Housecknecht, K.L.1    Mantzoros, C.S.2    Kuliawat, R.3    Hadro, E.4    Flier, J.S.5    Kahn, B.B.6
  • 73
    • 0033019136 scopus 로고    scopus 로고
    • In vivo and in vitro ob gene expression and leptin secretion in rat adipocytes. evidence for a regional specific regulation by sex steroid hormones
    • Machinal F., Dieudonne M.N., Leneveu M.C., Pecquery R., and Guidicelli Y. In vivo and in vitro ob gene expression and leptin secretion in rat adipocytes. evidence for a regional specific regulation by sex steroid hormones. Endocrinology 140 (1999) 1567-1574
    • (1999) Endocrinology , vol.140 , pp. 1567-1574
    • Machinal, F.1    Dieudonne, M.N.2    Leneveu, M.C.3    Pecquery, R.4    Guidicelli, Y.5
  • 74
    • 0030942844 scopus 로고    scopus 로고
    • The leptin receptor
    • Tartaglia L.A. The leptin receptor. J Biol Chem 272 (1997) 6093-6096
    • (1997) J Biol Chem , vol.272 , pp. 6093-6096
    • Tartaglia, L.A.1
  • 75
    • 0032444364 scopus 로고    scopus 로고
    • Cellular mechanism of pulsatile LHRH release
    • Terasawa F. Cellular mechanism of pulsatile LHRH release. Gen Com Endocrinol 112 (1998) 283-295
    • (1998) Gen Com Endocrinol , vol.112 , pp. 283-295
    • Terasawa, F.1
  • 77
    • 0030790504 scopus 로고    scopus 로고
    • The adipose obese gene product, leptin. evidence of a direct inhibitory role in ovarian function
    • Spicer J.L., and Francisco C.C. The adipose obese gene product, leptin. evidence of a direct inhibitory role in ovarian function. Endocrinology 138 (1997) 3374-3379
    • (1997) Endocrinology , vol.138 , pp. 3374-3379
    • Spicer, J.L.1    Francisco, C.C.2
  • 80
    • 0030010388 scopus 로고    scopus 로고
    • Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
    • Chehab F.F., Lim M.E., and Lu R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet 12 (1996) 318-320
    • (1996) Nat Genet , vol.12 , pp. 318-320
    • Chehab, F.F.1    Lim, M.E.2    Lu, R.3
  • 81
    • 0036800760 scopus 로고    scopus 로고
    • Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
    • Faroqui L.S., Matarese G., Lord G.M., Keogh J.M., Lawrence E., Agwu C., et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 110 (2002) 1093-1103
    • (2002) J Clin Invest , vol.110 , pp. 1093-1103
    • Faroqui, L.S.1    Matarese, G.2    Lord, G.M.3    Keogh, J.M.4    Lawrence, E.5    Agwu, C.6
  • 82
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clement K., Vaisse C., Lahlou N., Cabrol S., Pelloux V., Cassuto D., et al. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 392 (1998) 398-401
    • (1998) Nature , vol.392 , pp. 398-401
    • Clement, K.1    Vaisse, C.2    Lahlou, N.3    Cabrol, S.4    Pelloux, V.5    Cassuto, D.6
  • 83
    • 0036317022 scopus 로고    scopus 로고
    • Effect of leptin replacement on pituitary hormone regulation in patients with severe lipodystrophy
    • Oral E.A., Ruiz E., Andewelt A., Sebring N., Wagner A.J., Depaoli A.M., et al. Effect of leptin replacement on pituitary hormone regulation in patients with severe lipodystrophy. J Clin Endocrinol Metab 87 (2002) 3110-3117
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3110-3117
    • Oral, E.A.1    Ruiz, E.2    Andewelt, A.3    Sebring, N.4    Wagner, A.J.5    Depaoli, A.M.6
  • 85
    • 2542487416 scopus 로고    scopus 로고
    • Minireviw. a hypothalamic role in energy balance with special emphasis on leptin
    • Sahu A. Minireviw. a hypothalamic role in energy balance with special emphasis on leptin. Endocrinology 145 (2004) 2613-2620
    • (2004) Endocrinology , vol.145 , pp. 2613-2620
    • Sahu, A.1
  • 86
    • 0031464271 scopus 로고    scopus 로고
    • Gender differences in serum leptin in obese people. relationship with testosterone, body fat distribution and insulin sensitivity
    • Vettor R., De Pergola G., Pagano C., Englaro P., Laudadio E., Giorgino F., et al. Gender differences in serum leptin in obese people. relationship with testosterone, body fat distribution and insulin sensitivity. Eur J Clin Invest 27 (1997) 1016-1024
    • (1997) Eur J Clin Invest , vol.27 , pp. 1016-1024
    • Vettor, R.1    De Pergola, G.2    Pagano, C.3    Englaro, P.4    Laudadio, E.5    Giorgino, F.6
  • 88
    • 0030848557 scopus 로고    scopus 로고
    • Contribution of androgens to the gender differences in leptin production in obese children and adolescents
    • Wabitsch M., Blum W.S., Muche R., Braun M., Hube F., Rascher W., et al. Contribution of androgens to the gender differences in leptin production in obese children and adolescents. J Clin Invest 100 (1997) 808-813
    • (1997) J Clin Invest , vol.100 , pp. 808-813
    • Wabitsch, M.1    Blum, W.S.2    Muche, R.3    Braun, M.4    Hube, F.5    Rascher, W.6
  • 90
    • 0033304558 scopus 로고    scopus 로고
    • Leptin and androgens in male obesity. evidence for leptin contribution to reduced androgen levels
    • Isidori A.M., Caprio M., Strollo F., Moretti C., Frajese G., Isidori A., et al. Leptin and androgens in male obesity. evidence for leptin contribution to reduced androgen levels. J Clin Endocrinol Metab 84 (1999) 3673-3680
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3673-3680
    • Isidori, A.M.1    Caprio, M.2    Strollo, F.3    Moretti, C.4    Frajese, G.5    Isidori, A.6
  • 91
    • 0033055585 scopus 로고    scopus 로고
    • Leptin antagonizes the insulin-like factor-1 augmentation of steroidogenesis in granulosa and theca cells of the human ovary
    • Agarwal S.K., Vogel k., Weistman S.R., and Magoffin D.A. Leptin antagonizes the insulin-like factor-1 augmentation of steroidogenesis in granulosa and theca cells of the human ovary. J Clin Endocrinol Metab 84 (1999) 1072-1076
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1072-1076
    • Agarwal, S.K.1    Vogel, k.2    Weistman, S.R.3    Magoffin, D.A.4
  • 92
    • 0031983521 scopus 로고    scopus 로고
    • Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis
    • Spicer J.L., and Francisco C.C. Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis. Biol Reprod 58 (1998) 207-212
    • (1998) Biol Reprod , vol.58 , pp. 207-212
    • Spicer, J.L.1    Francisco, C.C.2
  • 94
    • 0031046147 scopus 로고    scopus 로고
    • Direct intraovarian effects of leptin. impairment of the synergistic action of insulin-like growth factor-I on FSH-dependent 17β-estradiol production by rat ovarian granulosa cells
    • Zachow R.J., and Magoffin D.A. Direct intraovarian effects of leptin. impairment of the synergistic action of insulin-like growth factor-I on FSH-dependent 17β-estradiol production by rat ovarian granulosa cells. Endocrinology 1378 (1997) 847-850
    • (1997) Endocrinology , vol.1378 , pp. 847-850
    • Zachow, R.J.1    Magoffin, D.A.2
  • 95
    • 0036693293 scopus 로고    scopus 로고
    • Impact of obesity and leptin levels on the secretion of estradiol inhibin A and inhibin B during ovarian stimulation with gonadotropins
    • Urbancsek J., Fedorcsak P., Klinga K., Devènyi N., Papp Z., Rabe T., et al. Impact of obesity and leptin levels on the secretion of estradiol inhibin A and inhibin B during ovarian stimulation with gonadotropins. Gynecol Endocrinol 16 (2004) 285-292
    • (2004) Gynecol Endocrinol , vol.16 , pp. 285-292
    • Urbancsek, J.1    Fedorcsak, P.2    Klinga, K.3    Devènyi, N.4    Papp, Z.5    Rabe, T.6
  • 96
    • 2642683229 scopus 로고    scopus 로고
    • C-peptide and insulin, but not c19 steroids, support the predictive value of body mass index on leptin in serum of premenopausal women
    • Geisthovel F., Meysing A., and Brabant G. C-peptide and insulin, but not c19 steroids, support the predictive value of body mass index on leptin in serum of premenopausal women. Hum Reprod 13 (1998) 547-553
    • (1998) Hum Reprod , vol.13 , pp. 547-553
    • Geisthovel, F.1    Meysing, A.2    Brabant, G.3
  • 99
    • 0031903341 scopus 로고    scopus 로고
    • Serum leptin in obese women with polycystic ovary syndrome is correlated with body weight and fat distribution but not with androgen and insulin levels
    • Vicennati V., Gambineri A., Calzoni L., Casimirri F., Macor C., Vettor R., et al. Serum leptin in obese women with polycystic ovary syndrome is correlated with body weight and fat distribution but not with androgen and insulin levels. Metabolism 47 (1998) 988-992
    • (1998) Metabolism , vol.47 , pp. 988-992
    • Vicennati, V.1    Gambineri, A.2    Calzoni, L.3    Casimirri, F.4    Macor, C.5    Vettor, R.6
  • 100
    • 0034880392 scopus 로고    scopus 로고
    • Disruption of the synchronous secretion of leptin, LH, and ovarian androgens in nonobese adolescents with the polycystic ovarian syndrome
    • Veldhuis J.D., Pincus S.M., Garcia-Rudaz M.C., Ropelato M.G., Escobar M.E., and Barontini M. Disruption of the synchronous secretion of leptin, LH, and ovarian androgens in nonobese adolescents with the polycystic ovarian syndrome. J Clin Endocrinol Metab 86 (2001) 3772-3778
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3772-3778
    • Veldhuis, J.D.1    Pincus, S.M.2    Garcia-Rudaz, M.C.3    Ropelato, M.G.4    Escobar, M.E.5    Barontini, M.6
  • 102
    • 0033805978 scopus 로고    scopus 로고
    • Preliminary evidence that ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans
    • Arvat E., Di Vito L., Broglio F., Papotti M., Muccioli G., Dieguez C., et al. Preliminary evidence that ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans. J Endocrinol Invest 23 (2000) 493-495
    • (2000) J Endocrinol Invest , vol.23 , pp. 493-495
    • Arvat, E.1    Di Vito, L.2    Broglio, F.3    Papotti, M.4    Muccioli, G.5    Dieguez, C.6
  • 103
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone releasing acylated peptide from stomach. Nature 402 (1999) 656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 104
    • 0013493636 scopus 로고    scopus 로고
    • Ghrelin. the link connecting growth with metabolism and energy homeostasis
    • Casanueva F., and Dieguez G. Ghrelin. the link connecting growth with metabolism and energy homeostasis. Rev Endocr Metab Dis 3 (2002) 325-338
    • (2002) Rev Endocr Metab Dis , vol.3 , pp. 325-338
    • Casanueva, F.1    Dieguez, G.2
  • 106
    • 18244391222 scopus 로고    scopus 로고
    • Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion
    • Shiiya T., Nakazato M., Minuta M., Date Y., Mondal M.S., Tanaka M., et al. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 87 (2002) 240-244
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 240-244
    • Shiiya, T.1    Nakazato, M.2    Minuta, M.3    Date, Y.4    Mondal, M.S.5    Tanaka, M.6
  • 107
    • 3142658638 scopus 로고    scopus 로고
    • Alterations of the dynamics of circulating ghrelin, adiponectin, and leptin in humans
    • Yildiz B.O., Suckard M.A., Wong Ml., McCann S.M., and Licinio J. Alterations of the dynamics of circulating ghrelin, adiponectin, and leptin in humans. Proc Natl Acad Sci U S A 101 (2004) 10434-10439
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10434-10439
    • Yildiz, B.O.1    Suckard, M.A.2    Wong, Ml.3    McCann, S.M.4    Licinio, J.5
  • 109
    • 0036688882 scopus 로고    scopus 로고
    • Role of ghrelin polymorphism in obesity based on three different studies
    • Ukkola O., Ravussin E., Jacobson P., Perisse l., Rankinen T., Tschop M., et al. Role of ghrelin polymorphism in obesity based on three different studies. Obes Res 10 (2002) 782-791
    • (2002) Obes Res , vol.10 , pp. 782-791
    • Ukkola, O.1    Ravussin, E.2    Jacobson, P.3    Perisse, l.4    Rankinen, T.5    Tschop, M.6
  • 110
    • 1042267409 scopus 로고    scopus 로고
    • Prader-Willy syndrome. advances in genetics, pathophysiology and treatment
    • Goldstone A.P. Prader-Willy syndrome. advances in genetics, pathophysiology and treatment. Trends Endocrinol Metab 15 (2004) 12-20
    • (2004) Trends Endocrinol Metab , vol.15 , pp. 12-20
    • Goldstone, A.P.1
  • 112
    • 0038030760 scopus 로고    scopus 로고
    • Ghrelin secretion in humans is sexually dymorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels
    • Barkan A.L., Dimaraki E.V., Jessup S.K., Symons K.V., Ermolenko M., and Jaffe C.A. Ghrelin secretion in humans is sexually dymorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels. J Clin Endocrinol Metab 88 (2003) 2180-2184
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2180-2184
    • Barkan, A.L.1    Dimaraki, E.V.2    Jessup, S.K.3    Symons, K.V.4    Ermolenko, M.5    Jaffe, C.A.6
  • 113
    • 2942528459 scopus 로고    scopus 로고
    • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
    • van der Lely A.J., Thchop M., Heiman M.L., and Ghigo E. Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocr Rev 25 (2004) 426-457
    • (2004) Endocr Rev , vol.25 , pp. 426-457
    • van der Lely, A.J.1    Thchop, M.2    Heiman, M.L.3    Ghigo, E.4
  • 115
    • 3042735648 scopus 로고    scopus 로고
    • The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans
    • Gnanapavan S., Kola B., Bustin S.A., Morris D.G., McGee P., Fairclough, et al. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab 87 (2002) 2988-2991
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2988-2991
    • Gnanapavan, S.1    Kola, B.2    Bustin, S.A.3    Morris, D.G.4    McGee, P.5    Fairclough6
  • 118
    • 0242432330 scopus 로고    scopus 로고
    • Developmental, stage-specific and hormonally regulated expression of growth hormone secretagogue receptor messenger ribonucleic acid in rat testis
    • Barreiro M.L., Suominen J.S., Gaytan F., Pinilla L., Chopin L.K., Casanueva F.F., et al. Developmental, stage-specific and hormonally regulated expression of growth hormone secretagogue receptor messenger ribonucleic acid in rat testis. Biol Reprod 68 (2003) 1631-1640
    • (2003) Biol Reprod , vol.68 , pp. 1631-1640
    • Barreiro, M.L.1    Suominen, J.S.2    Gaytan, F.3    Pinilla, L.4    Chopin, L.K.5    Casanueva, F.F.6
  • 119
    • 0035846447 scopus 로고    scopus 로고
    • Testis-specific and developmentally induced expression of a ghrelin gene-derived transcript that encodes a novel polypeptide in the mouse
    • Tanaka M., Hayashida Y., Nakao N., Nakai N., and Nakashima K. Testis-specific and developmentally induced expression of a ghrelin gene-derived transcript that encodes a novel polypeptide in the mouse. Biochem Biophys Acta 1522 (2001) 62-65
    • (2001) Biochem Biophys Acta , vol.1522 , pp. 62-65
    • Tanaka, M.1    Hayashida, Y.2    Nakao, N.3    Nakai, N.4    Nakashima, K.5
  • 122
    • 21444456024 scopus 로고    scopus 로고
    • Short-term modification of sex hormones is associated with changes in ghrelin circulating levels in healthy normal men
    • Gambineri A., Pagotto U., De Iasio R., Meriggiola M.C., Costantino A., Patton L., et al. Short-term modification of sex hormones is associated with changes in ghrelin circulating levels in healthy normal men. J Endocrinol Invest 28 (2005) 241-246
    • (2005) J Endocrinol Invest , vol.28 , pp. 241-246
    • Gambineri, A.1    Pagotto, U.2    De Iasio, R.3    Meriggiola, M.C.4    Costantino, A.5    Patton, L.6
  • 124
    • 0037329049 scopus 로고    scopus 로고
    • Immunolocalization of ghrelin and its functional receptor, the type 1a GH-secretagogue receptor, in the cyclic human ovary
    • Gaytán F., Barreiro M.L., Chopin L.K., Herington A.C., Morales C., Pinilla L., et al. Immunolocalization of ghrelin and its functional receptor, the type 1a GH-secretagogue receptor, in the cyclic human ovary. J Clin Endocrinol Metab 88 (2003) 879-887
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 879-887
    • Gaytán, F.1    Barreiro, M.L.2    Chopin, L.K.3    Herington, A.C.4    Morales, C.5    Pinilla, L.6
  • 125
    • 0038030760 scopus 로고    scopus 로고
    • Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels
    • Barkan A.L., Dimaraki E.V., Jessup S.K., Symons K.V., Ermolenko M., Jaffe C.A., et al. Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels. J Clin Endocrinol Metab 88 (2003) 2180-2184
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2180-2184
    • Barkan, A.L.1    Dimaraki, E.V.2    Jessup, S.K.3    Symons, K.V.4    Ermolenko, M.5    Jaffe, C.A.6
  • 126
    • 17944379112 scopus 로고    scopus 로고
    • Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
    • 4753-48
    • Ariyasu H., Takaya K., Tagami T., Ogawa Y., Hosoda K., Akamizu T., et al. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab 86 (2001) 4753-48
    • (2001) J Clin Endocrinol Metab , vol.86
    • Ariyasu, H.1    Takaya, K.2    Tagami, T.3    Ogawa, Y.4    Hosoda, K.5    Akamizu, T.6
  • 127
    • 0036925201 scopus 로고    scopus 로고
    • Plasma ghrelin, obesity, and the polycystic ovary syndrome. correlation with insulin resistance and androgen levels
    • Pagotto U., Gambineri A., Vicennati V., Heiman M.L., Tschöp M., and Pasquali R. Plasma ghrelin, obesity, and the polycystic ovary syndrome. correlation with insulin resistance and androgen levels. J Clin Endocrinol Metab 87 (2002) 5625-5629
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5625-5629
    • Pagotto, U.1    Gambineri, A.2    Vicennati, V.3    Heiman, M.L.4    Tschöp, M.5    Pasquali, R.6
  • 129
    • 0142025214 scopus 로고    scopus 로고
    • Anti-androgen treatment increases circulating ghrelin levels in obese women with polycystic ovary syndrome
    • Gambineri A., Pagotto U., Tschöp M., Vicennati V., Manicardi E., Carcello A., et al. Anti-androgen treatment increases circulating ghrelin levels in obese women with polycystic ovary syndrome. J Endocrinol Invest 26 (2003) 493-498
    • (2003) J Endocrinol Invest , vol.26 , pp. 493-498
    • Gambineri, A.1    Pagotto, U.2    Tschöp, M.3    Vicennati, V.4    Manicardi, E.5    Carcello, A.6
  • 130
    • 3242730062 scopus 로고    scopus 로고
    • Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition
    • Moran L.J., Noakes M., Clifton P.M., Wittert G.A., Tomlinson L., Galletly C., et al. Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. J Clin Endocrinol Metab 89 (2004) 3337-3344
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3337-3344
    • Moran, L.J.1    Noakes, M.2    Clifton, P.M.3    Wittert, G.A.4    Tomlinson, L.5    Galletly, C.6
  • 131
    • 0028033594 scopus 로고
    • The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function
    • Chamberlain N.L., Driver E.D., and Miesfeld R.L. The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function. Nucleic Acids Res 22 (1994) 3181-3186
    • (1994) Nucleic Acids Res , vol.22 , pp. 3181-3186
    • Chamberlain, N.L.1    Driver, E.D.2    Miesfeld, R.L.3
  • 132
    • 0028922314 scopus 로고
    • Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor. possible pathogenetic relevance for the (CAG)n-expanded neuropathies
    • Kazemi-Esfariani P., trifiro M.A., and Pinski L. Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor. possible pathogenetic relevance for the (CAG)n-expanded neuropathies. Hum Mol Genet 4 (1995) 523-527
    • (1995) Hum Mol Genet , vol.4 , pp. 523-527
    • Kazemi-Esfariani, P.1    trifiro, M.A.2    Pinski, L.3
  • 133
    • 0034976483 scopus 로고    scopus 로고
    • Polymorphisms of the androgen receptor gene and the estrogen beta gene are associated with androgen levels in women
    • Westberg I., Baghaei F., Rosmond R., Hellstrand M., Landen M., Jansson M., et al. Polymorphisms of the androgen receptor gene and the estrogen beta gene are associated with androgen levels in women. J Clin Endocrinol Metab 86 (2001) 2562-2568
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2562-2568
    • Westberg, I.1    Baghaei, F.2    Rosmond, R.3    Hellstrand, M.4    Landen, M.5    Jansson, M.6
  • 134
    • 0033978514 scopus 로고    scopus 로고
    • Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamide length
    • Irvine R.A., Ma H., Yu M.C., Ross R.K., Stallcup M.R., and Coetzee G.A. Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamide length. Hum Mol Genet 9 (2000) 267-274
    • (2000) Hum Mol Genet , vol.9 , pp. 267-274
    • Irvine, R.A.1    Ma, H.2    Yu, M.C.3    Ross, R.K.4    Stallcup, M.R.5    Coetzee, G.A.6
  • 136
    • 0032786806 scopus 로고    scopus 로고
    • Evidence that the CAG repeat in the androgen receptor gene is associated with the age-related decline in serum androgen levels in men
    • Krithivas K., Yurgalevitch S.M., Mohr B.A., Wilcox C.J., Batter S.J., Brown M., et al. Evidence that the CAG repeat in the androgen receptor gene is associated with the age-related decline in serum androgen levels in men. J Endocrinol 162 (1999) 137-142
    • (1999) J Endocrinol , vol.162 , pp. 137-142
    • Krithivas, K.1    Yurgalevitch, S.M.2    Mohr, B.A.3    Wilcox, C.J.4    Batter, S.J.5    Brown, M.6
  • 139
    • 0033592186 scopus 로고    scopus 로고
    • Linkage between male infertility and tronucleotide repeat expansion in the androgen-receptor gene
    • Dowsing A.T., Young E.L., Clarck M., McLachlan R.I., de Kretser D.M., and Trounson A.O. Linkage between male infertility and tronucleotide repeat expansion in the androgen-receptor gene. Lancet 354 (1999) 640-643
    • (1999) Lancet , vol.354 , pp. 640-643
    • Dowsing, A.T.1    Young, E.L.2    Clarck, M.3    McLachlan, R.I.4    de Kretser, D.M.5    Trounson, A.O.6
  • 140
    • 0037260483 scopus 로고    scopus 로고
    • Androgen receptor gene repeats and indices of obesity in older adults
    • Gustafson D.R., Wen M.J., and Koppanati B.M. Androgen receptor gene repeats and indices of obesity in older adults. Int J Obes 27 (2003) 75-81
    • (2003) Int J Obes , vol.27 , pp. 75-81
    • Gustafson, D.R.1    Wen, M.J.2    Koppanati, B.M.3
  • 141
    • 0033724587 scopus 로고    scopus 로고
    • Androgen receptor gene CAG trinucleotide repeats in anovulatoty infertility and polycystic ovaries
    • Mifsud A., Ramirez S., and Yong E.L. Androgen receptor gene CAG trinucleotide repeats in anovulatoty infertility and polycystic ovaries. J Clin Endocrinol Metab 83 (2000) 3484-3488
    • (2000) J Clin Endocrinol Metab , vol.83 , pp. 3484-3488
    • Mifsud, A.1    Ramirez, S.2    Yong, E.L.3
  • 142
    • 0036146428 scopus 로고    scopus 로고
    • The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian caucasian women with infertility related to polycystic ovary syndrome
    • The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian caucasian women with infertility related to polycystic ovary syndrome. J Clin Endocrinol Metab 87 (2002) 161-165
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 161-165
  • 143
    • 0028238319 scopus 로고
    • Size polymorphism of the androgen receptor among female hispanics and correlation with androgenic characteristics
    • Legro R.S., Shabahrami B., Lobo R.A., and Kovacs B.W. Size polymorphism of the androgen receptor among female hispanics and correlation with androgenic characteristics. Obstet Gynecol 83 (1994) 701-706
    • (1994) Obstet Gynecol , vol.83 , pp. 701-706
    • Legro, R.S.1    Shabahrami, B.2    Lobo, R.A.3    Kovacs, B.W.4
  • 145
    • 0035989073 scopus 로고    scopus 로고
    • Intrinsic regional differences in androgen receptors and dihydrotestosterone metabolism in human preadipocytes
    • Joyner J., Hutley L., and Cameron D. Intrinsic regional differences in androgen receptors and dihydrotestosterone metabolism in human preadipocytes. Horm Metab Res 34 (2002) 223-228
    • (2002) Horm Metab Res , vol.34 , pp. 223-228
    • Joyner, J.1    Hutley, L.2    Cameron, D.3
  • 147
    • 0037902870 scopus 로고    scopus 로고
    • Behind adrenal and ovarian androgen generation. increased peripheral 5a-reductase activity in women with polycystic ovary syndrome
    • Fassnacht M., Schlenz N., Schneider S.B., Wudy S.A., Allolio B., and Arlt W. Behind adrenal and ovarian androgen generation. increased peripheral 5a-reductase activity in women with polycystic ovary syndrome. J Clin Endocrinol Metab 88 (2003) 2760-2766
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2760-2766
    • Fassnacht, M.1    Schlenz, N.2    Schneider, S.B.3    Wudy, S.A.4    Allolio, B.5    Arlt, W.6
  • 148
    • 0035931115 scopus 로고    scopus 로고
    • A guide to 17 β-hydroxysteroid dehydrogenases
    • Adamski J., and Jacob F.J. A guide to 17 β-hydroxysteroid dehydrogenases. Mol Cell Endocrinol 171 (2001) 1-4
    • (2001) Mol Cell Endocrinol , vol.171 , pp. 1-4
    • Adamski, J.1    Jacob, F.J.2
  • 149
    • 0034993363 scopus 로고    scopus 로고
    • Analysis and characteristics of multiple types of human 17β-hydroxysteroid dehydrogenases
    • Luu-The V. Analysis and characteristics of multiple types of human 17β-hydroxysteroid dehydrogenases. J Steroid Biochem Mol Biol 76 (2001) 143-151
    • (2001) J Steroid Biochem Mol Biol , vol.76 , pp. 143-151
    • Luu-The, V.1
  • 150
    • 0036171657 scopus 로고    scopus 로고
    • The effect of obesity and the ratio of type 3 17β-hydroxysteroid dehydrogenase mRNA to cytochrome P450 aromatase mRNA in subcutaneous abdominal and intra-abdominal adipose tissue in women
    • Corbould A.M., Badwen M.J., Lavranos T.C., Rogers R.J., and Judd D.J. The effect of obesity and the ratio of type 3 17β-hydroxysteroid dehydrogenase mRNA to cytochrome P450 aromatase mRNA in subcutaneous abdominal and intra-abdominal adipose tissue in women. Int J Obes 26 (2002) 165-175
    • (2002) Int J Obes , vol.26 , pp. 165-175
    • Corbould, A.M.1    Badwen, M.J.2    Lavranos, T.C.3    Rogers, R.J.4    Judd, D.J.5
  • 151
    • 0001429526 scopus 로고    scopus 로고
    • Characteristics of a highly labile human type 5 17β-hydroxysteroid dehydrogenase
    • Dufort I., Rheault P., Huang X.-F., Soucy P., and Luu-The V. Characteristics of a highly labile human type 5 17β-hydroxysteroid dehydrogenase. Endocrinology 140 (1999) 568-574
    • (1999) Endocrinology , vol.140 , pp. 568-574
    • Dufort, I.1    Rheault, P.2    Huang, X.-F.3    Soucy, P.4    Luu-The, V.5
  • 152
    • 0034287545 scopus 로고    scopus 로고
    • Human 3a-hydroxysteroid dehydrogenases isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily. functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
    • Penning T.M., Burczynski M.E., Jez J.M., Hung C.F., Lin H.K., Ma H., et al. Human 3a-hydroxysteroid dehydrogenases isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily. functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones. Biochem J 351 (2003) 67-77
    • (2003) Biochem J , vol.351 , pp. 67-77
    • Penning, T.M.1    Burczynski, M.E.2    Jez, J.M.3    Hung, C.F.4    Lin, H.K.5    Ma, H.6
  • 154
    • 9444222625 scopus 로고    scopus 로고
    • Androgen generation in adipose tissue in women with simple obesity-a site-specific role for 17β-hydroxysteroid dehydrogenase type 5
    • Quinkler M., Sinha B., Tomlinson J.W., Bujalska I.J., Stewart P.M., and Artl W. Androgen generation in adipose tissue in women with simple obesity-a site-specific role for 17β-hydroxysteroid dehydrogenase type 5. J Endocrinol 183 (2004) 331-342
    • (2004) J Endocrinol , vol.183 , pp. 331-342
    • Quinkler, M.1    Sinha, B.2    Tomlinson, J.W.3    Bujalska, I.J.4    Stewart, P.M.5    Artl, W.6
  • 155
    • 0242468434 scopus 로고    scopus 로고
    • Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway
    • Singh R., Artaza J.N., Taylor W.E., Gonzales-Cadavid N.F., and Bhasin S. Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology 144 (2003) 5081-5088
    • (2003) Endocrinology , vol.144 , pp. 5081-5088
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Gonzales-Cadavid, N.F.4    Bhasin, S.5
  • 156
    • 0031798630 scopus 로고    scopus 로고
    • Androgen receptors in human preadipocytes and adipocytes. regional specificities and regulation by sex steroids
    • Dieudonne M.N., Pecquery R., Boumedienne A., Leneveu M.C., and Guidicelly Y. Androgen receptors in human preadipocytes and adipocytes. regional specificities and regulation by sex steroids. Am J Physiol 274 (1998) C1645-C1652
    • (1998) Am J Physiol , vol.274
    • Dieudonne, M.N.1    Pecquery, R.2    Boumedienne, A.3    Leneveu, M.C.4    Guidicelly, Y.5
  • 157
    • 85057489107 scopus 로고    scopus 로고
    • Endocrine determinants of fat distribution
    • Bray G., and Bouchard C. (Eds), Marcel Dekker, New York
    • Pasquali R., Vicennati V., and Pagotto U. Endocrine determinants of fat distribution. In: Bray G., and Bouchard C. (Eds). Handbook of obesity (2003), Marcel Dekker, New York 671-692
    • (2003) Handbook of obesity , pp. 671-692
    • Pasquali, R.1    Vicennati, V.2    Pagotto, U.3
  • 158
    • 0019422161 scopus 로고
    • Tissue lipoprotein lipase activity and its action in lipoprotein metabolism
    • Cryer A. Tissue lipoprotein lipase activity and its action in lipoprotein metabolism. J Biochem 13 (1981) 525-541
    • (1981) J Biochem , vol.13 , pp. 525-541
    • Cryer, A.1
  • 159
    • 0031711943 scopus 로고    scopus 로고
    • L'adipocyte, cellule sécrétrice et endocrine
    • Ailhaud G. L'adipocyte, cellule sécrétrice et endocrine. Méd/Sci 14 (1998) 858-864
    • (1998) Méd/Sci , vol.14 , pp. 858-864
    • Ailhaud, G.1
  • 160
    • 4243548752 scopus 로고
    • High adipose tissue lipoprotein lipase activity plays a causal role in the etiology of obesity
    • Angel A., Anderson H., Bouchard C., Lau D., Leiter L., and Mendelson R. (Eds), John Libbey, London
    • Kern P.A. High adipose tissue lipoprotein lipase activity plays a causal role in the etiology of obesity. In: Angel A., Anderson H., Bouchard C., Lau D., Leiter L., and Mendelson R. (Eds). Progress in obesity research. Proceedings of the 7th International Congress on Obesity; 1994; Toronto, Canada (1994), John Libbey, London 89-94
    • (1994) Progress in obesity research. Proceedings of the 7th International Congress on Obesity; 1994; Toronto, Canada , pp. 89-94
    • Kern, P.A.1
  • 161
    • 7044250697 scopus 로고    scopus 로고
    • Direct effect of sex steroid hormones on adipose tissue and obesity
    • Mayes J.S., and Watson Gh. Direct effect of sex steroid hormones on adipose tissue and obesity. Obes Rev 5 (2004) 197-216
    • (2004) Obes Rev , vol.5 , pp. 197-216
    • Mayes, J.S.1    Watson, Gh.2
  • 162
    • 0030857555 scopus 로고    scopus 로고
    • Sex differences in visceral fat lipolysis and metabolic complications of obesity
    • Lonnqvist F., Thorne A., Large V., and Arner P. Sex differences in visceral fat lipolysis and metabolic complications of obesity. Arterioscler Thromb Vasc Biol 17 (1997) 1472-1480
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1472-1480
    • Lonnqvist, F.1    Thorne, A.2    Large, V.3    Arner, P.4
  • 163
    • 0030967580 scopus 로고    scopus 로고
    • Glucose and free fatty acid metabolism in human obesity. Relationships to insulin resistance
    • Bonadonna R., and Bonora E. Glucose and free fatty acid metabolism in human obesity. Relationships to insulin resistance. Diabetes Rev 5 (1997) 21-51
    • (1997) Diabetes Rev , vol.5 , pp. 21-51
    • Bonadonna, R.1    Bonora, E.2
  • 164
    • 0027287413 scopus 로고
    • Fat cell adrenergic receptors and the control of white and brown fat cell function
    • Lafontan M., and Berlan M. Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res 34 (1993) 1057-1091
    • (1993) J Lipid Res , vol.34 , pp. 1057-1091
    • Lafontan, M.1    Berlan, M.2
  • 165
    • 0030816898 scopus 로고    scopus 로고
    • Comparison of hormone-sensitive lipase activity in visceral and subcutaneous human adipose tissue
    • Reynisdottir S., Dauzats M., Thorne A., and Langin D. Comparison of hormone-sensitive lipase activity in visceral and subcutaneous human adipose tissue. J Clin Endocrinol Metab 82 (1997) 4162-4166
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4162-4166
    • Reynisdottir, S.1    Dauzats, M.2    Thorne, A.3    Langin, D.4
  • 166
    • 0025110822 scopus 로고
    • Androgen binding to ammonium sulfate precipitates of human adipose tissue cytosols
    • Miller L.K., Kral J.G., Strain G.W., and Zumoff B. Androgen binding to ammonium sulfate precipitates of human adipose tissue cytosols. Steroids 55 (1990) 410-415
    • (1990) Steroids , vol.55 , pp. 410-415
    • Miller, L.K.1    Kral, J.G.2    Strain, G.W.3    Zumoff, B.4
  • 167
    • 0025633635 scopus 로고
    • Up-regulation of androgen receptor binding in male rat fat pad adipose precursor cells exposed to testosterone. study in a whole cell assay system
    • De Pergola G., Xu X.F., Yang S.M., Giorgino R., and Bjorntorp P. Up-regulation of androgen receptor binding in male rat fat pad adipose precursor cells exposed to testosterone. study in a whole cell assay system. J Steroid Biochem Mol Biol 37 (1990) 553-558
    • (1990) J Steroid Biochem Mol Biol , vol.37 , pp. 553-558
    • De Pergola, G.1    Xu, X.F.2    Yang, S.M.3    Giorgino, R.4    Bjorntorp, P.5
  • 168
    • 1842833569 scopus 로고    scopus 로고
    • Effect of testosterone on lipolysis in human pre-adipocytes from different fat depots
    • Dicker A., Ryden M., Naslund E., Muchlen I.E., Wiren M., Lafontan M., et al. Effect of testosterone on lipolysis in human pre-adipocytes from different fat depots. Diabetologia 47 (2004) 420-428
    • (2004) Diabetologia , vol.47 , pp. 420-428
    • Dicker, A.1    Ryden, M.2    Naslund, E.3    Muchlen, I.E.4    Wiren, M.5    Lafontan, M.6
  • 169
    • 0028797188 scopus 로고
    • Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men. effects of androgens
    • Marin P., Oden B., and Bjorntorp P. Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men. effects of androgens. J Clin Endocrinol Metab 80 (1995) 239-243
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 239-243
    • Marin, P.1    Oden, B.2    Bjorntorp, P.3
  • 171
    • 0026347185 scopus 로고
    • Postmenopausal hormone replacement therapy prevents central distribution of body fat after menopause
    • Haarbo J., Marslew U., Gottfredsen A., and Christiansen C. Postmenopausal hormone replacement therapy prevents central distribution of body fat after menopause. Metabolism 40 (1991) 323-326
    • (1991) Metabolism , vol.40 , pp. 323-326
    • Haarbo, J.1    Marslew, U.2    Gottfredsen, A.3    Christiansen, C.4
  • 172
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285 (2001) 2486-2497
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 173
    • 0033048634 scopus 로고    scopus 로고
    • Associations of obesity markers, insulin, and sex hormones with HDL-cholesterol levels in Turkish and German individuals
    • Hergenc G., Schulte H., Assmann G., and von Eckardstein A. Associations of obesity markers, insulin, and sex hormones with HDL-cholesterol levels in Turkish and German individuals. Atherosclerosis 145 (1999) 147-156
    • (1999) Atherosclerosis , vol.145 , pp. 147-156
    • Hergenc, G.1    Schulte, H.2    Assmann, G.3    von Eckardstein, A.4
  • 174
    • 0034128215 scopus 로고    scopus 로고
    • Low serum testosterone levels as a predictor of increased visceral fat in Japanese-American men
    • Tsai E.C., Boyko E.J., Leonetti D.L., and Fujimto W.Y. Low serum testosterone levels as a predictor of increased visceral fat in Japanese-American men. Int J Obes 24 (1996) 485-491
    • (1996) Int J Obes , vol.24 , pp. 485-491
    • Tsai, E.C.1    Boyko, E.J.2    Leonetti, D.L.3    Fujimto, W.Y.4
  • 175
    • 0031016129 scopus 로고    scopus 로고
    • Association between plasma total testosterone and cardiovascular risk factors in healthy adult men. the TELECOM study
    • Simon D., Charles M.A., Nahoul K., Orssaud G., Kremski J., Hully V., et al. Association between plasma total testosterone and cardiovascular risk factors in healthy adult men. the TELECOM study. J Clin Endocrinol Metab 82 (1997) 682-685
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 682-685
    • Simon, D.1    Charles, M.A.2    Nahoul, K.3    Orssaud, G.4    Kremski, J.5    Hully, V.6
  • 176
    • 0038495077 scopus 로고    scopus 로고
    • Testosterone for secondary prevention in men with ischaemic heart disease
    • Malkin C.J., Pugh P.J., Jones T.H., and Channer K.S. Testosterone for secondary prevention in men with ischaemic heart disease. Quat J Med 96 (2003) 521-529
    • (2003) Quat J Med , vol.96 , pp. 521-529
    • Malkin, C.J.1    Pugh, P.J.2    Jones, T.H.3    Channer, K.S.4
  • 177
    • 0034456450 scopus 로고    scopus 로고
    • Trasdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men
    • Testosterone gel study group
    • Wang C., Swerdloff R.S., Iranmanesh A., Dobs A., Snyder P.J., Cunningham G., et al., Testosterone gel study group. Trasdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. J Clin Endocrinol Metab 85 (2000) 2839-2853
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2839-2853
    • Wang, C.1    Swerdloff, R.S.2    Iranmanesh, A.3    Dobs, A.4    Snyder, P.J.5    Cunningham, G.6
  • 178
    • 0027102382 scopus 로고
    • The effects of testosterone treatment on body composition and metabolism in middle-aged obese men
    • Marin P., Holmang S., Jonsson L., Sjostrom L., Kvist H., Holm G., et al. The effects of testosterone treatment on body composition and metabolism in middle-aged obese men. Int J Obes 16 (1992) 991-997
    • (1992) Int J Obes , vol.16 , pp. 991-997
    • Marin, P.1    Holmang, S.2    Jonsson, L.3    Sjostrom, L.4    Kvist, H.5    Holm, G.6
  • 179
    • 0344210985 scopus 로고    scopus 로고
    • Effect of testosterone suppression in young men by the gonadotropin releasing hormone antagonist cetrorelix on plasma lipids, lipolytic enzymes, lipid transfer proteins, insulin, and leptin
    • Buchter D., Behere H.M., Kliesch S., Chirazi A., Nieschlag E., Assmann G., et al. Effect of testosterone suppression in young men by the gonadotropin releasing hormone antagonist cetrorelix on plasma lipids, lipolytic enzymes, lipid transfer proteins, insulin, and leptin. Exp Clin Endocr Diabetes 107 (1999) 522-529
    • (1999) Exp Clin Endocr Diabetes , vol.107 , pp. 522-529
    • Buchter, D.1    Behere, H.M.2    Kliesch, S.3    Chirazi, A.4    Nieschlag, E.5    Assmann, G.6
  • 180
    • 0026053850 scopus 로고
    • Low sex hormone binding globulin concentration as an independent risk factor for development of NIDDM. 12 yr follow-up of population study of women in Gotemburg
    • Lindstedt G., Lundberg P., Lapidus L., Lundgren H., Bengtsson C., and Bjorntorp P. Low sex hormone binding globulin concentration as an independent risk factor for development of NIDDM. 12 yr follow-up of population study of women in Gotemburg. Diabetes 40 (1991) 123-128
    • (1991) Diabetes , vol.40 , pp. 123-128
    • Lindstedt, G.1    Lundberg, P.2    Lapidus, L.3    Lundgren, H.4    Bengtsson, C.5    Bjorntorp, P.6
  • 181
    • 1842728480 scopus 로고    scopus 로고
    • Role of changes in dietary habits in polycystic ovary syndrome
    • Pasquali R., and Gambineri A. Role of changes in dietary habits in polycystic ovary syndrome. Reprod Biomed Online 8 (2004) 431-439
    • (2004) Reprod Biomed Online , vol.8 , pp. 431-439
    • Pasquali, R.1    Gambineri, A.2
  • 182
    • 0142185995 scopus 로고    scopus 로고
    • Insulin-lowering agents in the management of polycystic ovary syndrome
    • De Leo V., la Marca A., and Petraglia F. Insulin-lowering agents in the management of polycystic ovary syndrome. Endocr Rev 24 (2003) 633-667
    • (2003) Endocr Rev , vol.24 , pp. 633-667
    • De Leo, V.1    la Marca, A.2    Petraglia, F.3
  • 183
    • 1042276554 scopus 로고    scopus 로고
    • Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome
    • Gambineri A., Pelusi C., Genghini S., Morselli-Labate A.M., Cacciari M., Pagotto U., et al. Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 60 (2004) 241-249
    • (2004) Clin Endocrinol (Oxf) , vol.60 , pp. 241-249
    • Gambineri, A.1    Pelusi, C.2    Genghini, S.3    Morselli-Labate, A.M.4    Cacciari, M.5    Pagotto, U.6
  • 184
    • 0026637840 scopus 로고
    • The effects of short term testosterone exposure on insulin sensitivity in female rats
    • Holmang A., Larsson B.M., Brzezinska Z., and Bjorntorp P. The effects of short term testosterone exposure on insulin sensitivity in female rats. Am J Physiol 262 (1992) E851-E855
    • (1992) Am J Physiol , vol.262
    • Holmang, A.1    Larsson, B.M.2    Brzezinska, Z.3    Bjorntorp, P.4
  • 185
    • 0031985351 scopus 로고    scopus 로고
    • Imprinting of females offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats
    • Nilsson C., Niklasson M., Erikson E., Bjorntorp P., and Holmag A. Imprinting of females offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats. J Clin Invest 101 (1998) 74-78
    • (1998) J Clin Invest , vol.101 , pp. 74-78
    • Nilsson, C.1    Niklasson, M.2    Erikson, E.3    Bjorntorp, P.4    Holmag, A.5
  • 186
    • 0031456016 scopus 로고    scopus 로고
    • Insulin resistance and the polycystic ovary syndrome. mechanisms and implications for pathogenesis
    • Dunaif A. Insulin resistance and the polycystic ovary syndrome. mechanisms and implications for pathogenesis. Endocr Rev 18 (1997) 774-800
    • (1997) Endocr Rev , vol.18 , pp. 774-800
    • Dunaif, A.1
  • 187
    • 0038010509 scopus 로고    scopus 로고
    • Diabetes prevalence and risk factors in polycystic ovary syndrome
    • Legro R.S. Diabetes prevalence and risk factors in polycystic ovary syndrome. Curr Opin Endocrinol Diab 9 (2002) 451-458
    • (2002) Curr Opin Endocrinol Diab , vol.9 , pp. 451-458
    • Legro, R.S.1
  • 188
    • 4344592692 scopus 로고    scopus 로고
    • Glucose intolerance in a large cohort of Mediterranean women with polycystic ovary syndrome. Phenotype and associated factors
    • Gambineri A., Pelusi C., Manicardi E., Vicennati V., Cacciari M., Morselli-Labate A.M., et al. Glucose intolerance in a large cohort of Mediterranean women with polycystic ovary syndrome. Phenotype and associated factors. Diabetes 53 (2004) 2353-2358
    • (2004) Diabetes , vol.53 , pp. 2353-2358
    • Gambineri, A.1    Pelusi, C.2    Manicardi, E.3    Vicennati, V.4    Cacciari, M.5    Morselli-Labate, A.M.6
  • 189
    • 0038307320 scopus 로고    scopus 로고
    • Polycystic ovary syndrome and cardiovascular disease. a premature association?
    • Legro R.S. Polycystic ovary syndrome and cardiovascular disease. a premature association?. Endocr Rev 24 (2003) 302-312
    • (2003) Endocr Rev , vol.24 , pp. 302-312
    • Legro, R.S.1
  • 190
    • 0031036534 scopus 로고    scopus 로고
    • Achievement of near-normal body weight as the prerequisite to normalize sex hormone-binding globulin concentrations in massively obese men
    • Pasquali R., Vicennati V., Scopinaro N., Marinari G., Flamia R., Casimirri F., et al. Achievement of near-normal body weight as the prerequisite to normalize sex hormone-binding globulin concentrations in massively obese men. Int J Obes 21 (1997) 1-5
    • (1997) Int J Obes , vol.21 , pp. 1-5
    • Pasquali, R.1    Vicennati, V.2    Scopinaro, N.3    Marinari, G.4    Flamia, R.5    Casimirri, F.6
  • 191
    • 0023003363 scopus 로고
    • Sex steroid, gonadotropin, cortisol, and prolactin in healthy, massively obese women. correlation with abdominal fat cell size and effect of weight loss
    • Grenman S., Konnemaa T., Iryale K., Kaiola H.L., and Grouroos M. Sex steroid, gonadotropin, cortisol, and prolactin in healthy, massively obese women. correlation with abdominal fat cell size and effect of weight loss. J Clin Endocrinol Metab 63 (1986) 1257-1261
    • (1986) J Clin Endocrinol Metab , vol.63 , pp. 1257-1261
    • Grenman, S.1    Konnemaa, T.2    Iryale, K.3    Kaiola, H.L.4    Grouroos, M.5
  • 192
    • 0031027956 scopus 로고    scopus 로고
    • 17a-hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without polycystic ovary syndrome after dietary weight loss
    • Jakubowicz D.J., and Nestler J.E. 17a-hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without polycystic ovary syndrome after dietary weight loss. J Clin Endocrinol Metab 82 (1997) 556-560
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 556-560
    • Jakubowicz, D.J.1    Nestler, J.E.2
  • 193
    • 17744400090 scopus 로고    scopus 로고
    • Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome
    • Pasquali R., Gambineri A., Biscotti D., Vicennati V., Gagliardi L., Colitta D., et al. Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. J Clin Endocrinol Metab 85 (2000) 2767-2774
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2767-2774
    • Pasquali, R.1    Gambineri, A.2    Biscotti, D.3    Vicennati, V.4    Gagliardi, L.5    Colitta, D.6
  • 195
    • 0142247208 scopus 로고    scopus 로고
    • Metformin in polycystic ovary syndrome. systematic review and meta-analysis
    • Lord J.M., Flight I.H., and Norman R.J. Metformin in polycystic ovary syndrome. systematic review and meta-analysis. BMJ 25 327 (2003) 951-953
    • (2003) BMJ , vol.25 , Issue.327 , pp. 951-953
    • Lord, J.M.1    Flight, I.H.2    Norman, R.J.3
  • 196
    • 0036009792 scopus 로고    scopus 로고
    • Female androgen insufficiency. the Princeton consensus statement on definition, classification and assessment
    • Bachamann G.A., Bancroft G., Braunstein G., Burger S.R., Davis l., Dennerstein I., et al. Female androgen insufficiency. the Princeton consensus statement on definition, classification and assessment. Fertil Steril 77 (2002) 660-665
    • (2002) Fertil Steril , vol.77 , pp. 660-665
    • Bachamann, G.A.1    Bancroft, G.2    Braunstein, G.3    Burger, S.R.4    Davis, l.5    Dennerstein, I.6
  • 198
    • 0030010984 scopus 로고    scopus 로고
    • Exogenous androgens influence body composition and regional body fat distribution in obese postmenopausal women-a clinical research center study
    • Lovejoy J.C., Bray G.A., Bourgeois M.O., Macchiavelli R., Rood J.C., Greeson C., et al. Exogenous androgens influence body composition and regional body fat distribution in obese postmenopausal women-a clinical research center study. J Clin Endocrinol Metab 81 (1996) 2198-2203
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2198-2203
    • Lovejoy, J.C.1    Bray, G.A.2    Bourgeois, M.O.3    Macchiavelli, R.4    Rood, J.C.5    Greeson, C.6
  • 199
    • 0033692898 scopus 로고    scopus 로고
    • Effect of estradiol with or without testosterone on body composition and relationship with lipids in postmenopausal women
    • Davis S.R., Walker K.Z., and Strauss B.J. Effect of estradiol with or without testosterone on body composition and relationship with lipids in postmenopausal women. Menopause 7 (2000) 395-401
    • (2000) Menopause , vol.7 , pp. 395-401
    • Davis, S.R.1    Walker, K.Z.2    Strauss, B.J.3
  • 200
    • 0034618866 scopus 로고    scopus 로고
    • Transdermal testosterone treatment in women with impaired sexual function after oophorectomy
    • Shifren J.L., Braunstein J., Simon P., Casson J.E., Buster R.E., Red Burki E.S., et al. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. N Engl J Med 343 (2000) 682-688
    • (2000) N Engl J Med , vol.343 , pp. 682-688
    • Shifren, J.L.1    Braunstein, J.2    Simon, P.3    Casson, J.E.4    Buster, R.E.5    Red Burki, E.S.6
  • 201
    • 0008564051 scopus 로고    scopus 로고
    • Effects of androgens in men with the metabolic syndrome
    • Marin P. Effects of androgens in men with the metabolic syndrome. Aging Male 1 (1998) 129-136
    • (1998) Aging Male , vol.1 , pp. 129-136
    • Marin, P.1
  • 202
    • 0029263607 scopus 로고
    • Effects of testosterone and triglycerides uptake and mobilization in different adipose tissues in male rats in vivo
    • Li M., and Bjorntorp P. Effects of testosterone and triglycerides uptake and mobilization in different adipose tissues in male rats in vivo. Obes Res 3 (1995) 113-119
    • (1995) Obes Res , vol.3 , pp. 113-119
    • Li, M.1    Bjorntorp, P.2
  • 205
    • 1842863035 scopus 로고    scopus 로고
    • The ageing male: testosterone deficiency and testosterone replacement. An up-date
    • Alexandersen P., and Christensen C. The ageing male: testosterone deficiency and testosterone replacement. An up-date. Atherosclerosis 173 (2004) 157-169
    • (2004) Atherosclerosis , vol.173 , pp. 157-169
    • Alexandersen, P.1    Christensen, C.2
  • 206
    • 0742289422 scopus 로고    scopus 로고
    • Association of endogenous testosterone with blood pressure and left ventricular mass in men. The Tromso Study
    • Svartberg J., von Muhlen D., Schirmer H., Barret-Connor E., Sundfjord J., and Jorde R. Association of endogenous testosterone with blood pressure and left ventricular mass in men. The Tromso Study. Eur J Endocrinol 150 (2004) 65-71
    • (2004) Eur J Endocrinol , vol.150 , pp. 65-71
    • Svartberg, J.1    von Muhlen, D.2    Schirmer, H.3    Barret-Connor, E.4    Sundfjord, J.5    Jorde, R.6
  • 207
    • 0038823605 scopus 로고    scopus 로고
    • Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency
    • Boyanow M.A., Boneva Z., and Christov V.G. Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency. Aging Male 6 (2003) 1-7
    • (2003) Aging Male , vol.6 , pp. 1-7
    • Boyanow, M.A.1    Boneva, Z.2    Christov, V.G.3
  • 208
    • 0033013807 scopus 로고    scopus 로고
    • Antiandrogen treatment of polycystic ovary syndrome
    • Rittmaster R.S. Antiandrogen treatment of polycystic ovary syndrome. Endocrinol Metab Clin North Am 28 (1999) 409-421
    • (1999) Endocrinol Metab Clin North Am , vol.28 , pp. 409-421
    • Rittmaster, R.S.1
  • 209
    • 0022535044 scopus 로고
    • Treatment of hirsutism and acne with cyproterone acetate
    • Miller J.A., and Jabobs H.S. Treatment of hirsutism and acne with cyproterone acetate. Clin Endocrinol Metab 15 (1986) 373-389
    • (1986) Clin Endocrinol Metab , vol.15 , pp. 373-389
    • Miller, J.A.1    Jabobs, H.S.2
  • 210
    • 0022571455 scopus 로고
    • Paradoxical effects of the antiandrogen cyproterone acetate on lipid and lipoprotein metabolism
    • Wynn V., Godsland I.F., Seed M., and Jacobs H.S. Paradoxical effects of the antiandrogen cyproterone acetate on lipid and lipoprotein metabolism. Clin Endocrinol (Oxf) 24 (1986) 183-191
    • (1986) Clin Endocrinol (Oxf) , vol.24 , pp. 183-191
    • Wynn, V.1    Godsland, I.F.2    Seed, M.3    Jacobs, H.S.4
  • 211
  • 213
    • 0033694297 scopus 로고    scopus 로고
    • Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls. effect of flutamide
    • Ibánez L., Potau N., Marcos M.V., and De Zegher F. Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls. effect of flutamide. J Clin Endocrinol Metab 85 (2000) 3251-3255
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3251-3255
    • Ibánez, L.1    Potau, N.2    Marcos, M.V.3    De Zegher, F.4
  • 214
    • 0034523425 scopus 로고    scopus 로고
    • Polycystic ovarian syndrome. evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone
    • Eagleson C.A., Gingrich M.B., Pastor C.L., Azora T.K., Bust C.M., Evans W.S., et al. Polycystic ovarian syndrome. evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone. J Clin Endocrinol Metab 85 (2000) 4047-4052
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4047-4052
    • Eagleson, C.A.1    Gingrich, M.B.2    Pastor, C.L.3    Azora, T.K.4    Bust, C.M.5    Evans, W.S.6
  • 216
    • 0031726522 scopus 로고    scopus 로고
    • The effect of a pure antiandrogen receptor blocker, flutamide, on the lipid profile in the polycystic ovary syndrome
    • DiamantiKandarakis E., Mitrakou A., Raptis S., Tolis G., and Duleba A.J. The effect of a pure antiandrogen receptor blocker, flutamide, on the lipid profile in the polycystic ovary syndrome. J Clin Endocrinol Metab 83 (1998) 2699-2705
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2699-2705
    • DiamantiKandarakis, E.1    Mitrakou, A.2    Raptis, S.3    Tolis, G.4    Duleba, A.J.5
  • 217
    • 0024474182 scopus 로고
    • Flutamide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in advanced prostatic cancer
    • Brogden R.N., and Clissold S.P. Flutamide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in advanced prostatic cancer. Drugs 38 (1989) 185-203
    • (1989) Drugs , vol.38 , pp. 185-203
    • Brogden, R.N.1    Clissold, S.P.2
  • 218
    • 0023228346 scopus 로고
    • Inhibition of rat testicular 17a-hydroxylase and 17,20-lyase activities by antiandrogens (flutamide, hydroxyflutamide, RU 23908, cyproterone acetate) in vitro
    • Ayub M., and Levell M.J. Inhibition of rat testicular 17a-hydroxylase and 17,20-lyase activities by antiandrogens (flutamide, hydroxyflutamide, RU 23908, cyproterone acetate) in vitro. J Steroid Biochem 28 (1987) 43-50
    • (1987) J Steroid Biochem , vol.28 , pp. 43-50
    • Ayub, M.1    Levell, M.J.2
  • 219
    • 0038644550 scopus 로고    scopus 로고
    • Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism
    • Ibanez L., Ong K., Amin R., Dunger D., and de Zegher F. Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism. J Clin Endocrinol Metab 88 (2003) 2600-2606
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2600-2606
    • Ibanez, L.1    Ong, K.2    Amin, R.3    Dunger, D.4    de Zegher, F.5
  • 220
    • 10744232993 scopus 로고    scopus 로고
    • Flutamide-metformin therapy to reduce fat mass in hyperinsulinemic ovarian hyperandrogenism. effects in adolescents and in women on third-generation oral contraception
    • Ibanez L., and de Zegher F. Flutamide-metformin therapy to reduce fat mass in hyperinsulinemic ovarian hyperandrogenism. effects in adolescents and in women on third-generation oral contraception. J Clin Endocrinol Metab 88 (2003) 4720-4724
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4720-4724
    • Ibanez, L.1    de Zegher, F.2
  • 221
    • 11144354560 scopus 로고    scopus 로고
    • Ethynilestradiol-drospirenoine, fltamide-metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism. opposite effects on adipokines and body adiposity
    • Ibanez L., and de Zegher F. Ethynilestradiol-drospirenoine, fltamide-metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism. opposite effects on adipokines and body adiposity. J Clin Endocrinol Metab (2004) 1592-1594
    • (2004) J Clin Endocrinol Metab , pp. 1592-1594
    • Ibanez, L.1    de Zegher, F.2
  • 222
    • 0033833321 scopus 로고    scopus 로고
    • Drospirenone. pharmacology and pharmacokinetics of unique progestagen
    • Krattenmaker R. Drospirenone. pharmacology and pharmacokinetics of unique progestagen. Contraception 62 (2000) 29-38
    • (2000) Contraception , vol.62 , pp. 29-38
    • Krattenmaker, R.1
  • 223
    • 0032124873 scopus 로고    scopus 로고
    • Pituitary desensitization to gonadotropin-releasing hormone increases abdominal adiposity in hyperandrogenic anovulatory women
    • Dumesic D.A., Abbott D.H., Eisner J.R., Herrmann R.R., Reed J.E., Welch T.J., et al. Pituitary desensitization to gonadotropin-releasing hormone increases abdominal adiposity in hyperandrogenic anovulatory women. Fertil Steril 70 (1998) 94-101
    • (1998) Fertil Steril , vol.70 , pp. 94-101
    • Dumesic, D.A.1    Abbott, D.H.2    Eisner, J.R.3    Herrmann, R.R.4    Reed, J.E.5    Welch, T.J.6


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