Evidence for leptin binding to proteins in serum of rodents and humans: Modulation with obesity

Diabetes

Volumn 45, Issue 11, 1996, Pages 1638-1643

  Houseknecht, Karen L ^a   Mantzoros, Chris S ^a   Kuliawat, Regina ^a   Hadro, Edward ^a   Flier, Jeffrey S ^a   Kahn, Barbara B ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; GENE PRODUCT; PROTEIN; RECOMBINANT PROTEIN;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BINDING COMPETITION; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROPHORESIS; FEMALE; HUMAN; IMMUNOBLOTTING; ISOTOPE LABELING; MACROMOLECULE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BINDING; RADIOIMMUNOASSAY; SUCROSE GRADIENT;

EID: 0029907970     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.11.1638     Document Type: Article

References (21)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994
2. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on weight regulation in ob/ob mice. Science 269:540-543, 1995
3. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burkley SK, Friedman JM: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995
4. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549, 1995
5. Weigle DS, Bukowski TR, Foster DC, Holderman S, Kramer JM, Lasser G, Lofton-Day CE, Prunkard DE, Raymond C, Kuijper JL: Recombinant of protein reduces feeding and body weight in the ob/ob mouse. J Clin Invest 96:2005-2070, 1995
6. Stephens TW, Basinski M, Bristow PK, Bue-Valleskey JM, Burgett SG, Craft K, Hale J, Hoffmann J, Hsiung HM, Kriauciunas A, MacKeller W, Rosteck PR, Schoner B, Smith D, Tinsley FC, Zhang XY, Heiman M: The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377:530-532, 1995
7. Sainsbury A, Cusin I, Doyle P, Rohner-Jeanrenaud F, Jeanrenaud B: Intracerebroventricular administration of neuropeptide Y to normal rats increases obese gene expression in white adipose tissue. Diobetologia 39:353-356, 1996
8. Schwartz MW, Baskin DG, Bukowski TR, Kuijper JI, Foster D, Lasser G, Prunkard DE, Porte D, Woods SC, Seeley RJ, Weigle DS: Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in 06/06 mice. Diabetes 45:531-535, 1996
9. Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, Rosato EL, Colberg J, Caro JF: Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J Clin Invest 95:2986-2988, 1995
10. Frederich RC, Lollman B, Hamann A, Napolitano-Rosen A, Kahn BB, Lowell BB, Flier JS: Expression of ob mRNA and its encoded protein in rodents: impact of nutrition and obesity. J Clin Invest 96:1658-1663, 1995
11. Frederich RC, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier JS: Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nature Med 1:1311-1314, 1995
12. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature, Med 11:1155-1161, 1995
13. Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J: Identification and expression cloning of a leptin receptor, OB-R. Cell 83:1263-1271, 1995
14. Chen H, Chariat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84:491-495, 1996
15. Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM: Abnormal splicing of the leptin receptor in diabetic mice. Nature 379:632, 1996
16. Heaney ML, Golde DW: Soluble hormone receptors. Blood 82:1945-1948, 1993
17. Bonner JC, Brody AR: Cytokine-binding proteins in the lung. Am J Physiol 12:L869-L878, 1995
18. Lowell BB, Susulic VS, Hamann A, Lawitts JA, Himms-Hagen J, Boyer BB, Kozak LP, Flier JS: Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature 366:740-742, 1993
19. Gnudi L, Tozzo E, Shepherd PR, Bliss JL, Kahn BB: High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance. Endocrinology 135:995-1002, 1995
20. Baumann G: Growth hormone-binding proteins: state of the art. J Endocrinol 141:1-6, 1994
21. Clemmons DR: IGF binding proteins and their functions. Mol Reprod Dev 35:368-375, 1993