Androgen receptors in human preadipocytes and adipocytes: Regional specificities and regulation by sex steroids

American Journal of Physiology - Cell Physiology

Volumn 274, Issue 6 43-6, 1998, Pages

  Dieudonne M N ^a   Pecquery, R ^a   Boumediene, A ^a   Leneveu, M C ^a   Giudicelli, Y ^a  

^a CENTRE HOSPITALIER INTERCOMMUNAL   (France)

Author keywords

Adipogenesis; Cultured preadipocytes; Sex hormones

Indexed keywords

ANDROGEN RECEPTOR; SEX HORMONE;

ADIPOCYTE; ADULT; AGED; ANATOMICAL VARIATION; ANIMAL CELL; ARTICLE; BODY FAT; CELL CULTURE; CELL SPECIFICITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIPID STORAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; SEX DIFFERENCE;

ANIMALIA;

EID: 0031798630     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.274.6.c1645     Document Type: Article

References (41)

1. Beato, M. Gene regulation by steroid hormones. Cell 56: 335-344, 1989.
2. Berthois, Y., T. Dong, F. Roux-Dossetom, and P. M. Martin. Expression of estrogen receptor and its messenger ribonucleic acid in the MCF-7 cell line: multiparametric analysis of its processing and regulation by estrogen. Mol. Cell. Endocrinol. 74: 11-20, 1990.
3. Björntorp, P. The regulation of adipose tissue distribution in humans. Int. J. Obes. 20: 291-302, 1996.
4. Bradford, A. M. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72: 248-254, 1976.
5. Chang, C. S., J. Kokontis, and S. T. Liao. Molecular cloning of human and complementary DNA encoding androgen receptors. Science 240: 324-326, 1988.
6. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
7. De Pergola, G., X. Xu, S. Yang, R. Giorgino, and P. Björntorp. Up-regulation of androgen receptor binding in male rat fat pad adipose precursor cells exposed to testosterone: study in a whole cell assay system. J. Steroid Biochem. Mol. Biol. 37: 553-558, 1990.
8. Deslex, S., R. Negrel, and G. Ailhaud. Development of a chemically defined serum free medium for differentiation of rat adipose precursor cells. Exp. Cell Res. 168: 15-30, 1987.
9. Diaz-Sanchez, V., S. Morimoto, A. Morales, G. Robles-Diaz, and M. Cerbon. Androgen receptor in the rat pancreas: genetic expression and steroid regulation. Pancreas 11: 241-245, 1995.
10. 2/β-adrenoceptor-coupled adenylate cyclase system and their relationship with adrenergic responsiveness in hamster fat cells from different anatomical sites. Eur. J. Biochem. 205: 867-873, 1992.
11. Dieudonné, M. N., R. Pecquery, M. C. Leneveu, J. P. Dausse, and Y. Giudicelli. In vitro up-regulatory effect of testosterone on alpha(2)-adrenoreceptor expression in adipose tissue. Endocrine 2: 567-570, 1994.
12. Dieudonné, M. N., R. Pecquery, M. C. Leneveu, A. M. Jaubert, and Y. Giudicelli. Androgen receptors in cultured rat adipose precursor cells during proliferation and differentiation: regional specificities and regulation by testosterone. Endocrine 3: 537-541, 1995.
13. Hauner, H., P. Schmid, and E. F. Pfeiffer. Glucocorticoids and insulin promote the differentiation of human adipocyte precursor cells into fat cells. J. Clin. Endocrinol. Metab. 64: 832-835, 1987.
14. Jacobson, W., J. Routledge, H. Davies, T. Saich, I. Hughes, A. Brinkmann, B. Brown, and P. Clarkson. Localisation of androgen receptors in dermal fibroblasts, grown in vitro, from normal subjects and from patients with androgen insensitivity syndrome. Horm. Res. 44: 75-84, 1995.
15. Jaubert, A. M., R. Pecquery, I. Sichez, M. N. Dieudonné, J. F. Cloix, and Y. Giudicelli. Androgen receptors in hamster white adipocytes and their precursor cells: regional variations and modulation by androgens. Endocrine 1: 535-540, 1993.
16. Kemppainen, J. A., M. V. Lane, M. Sar, and E. M. Wilson. Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation - specificity for steroids and anti-hormones. J. Biol. Chem. 267: 968-974, 1992.
17. Krongrad, A., C. M. Wilson, J. D. Wilson, D. R. Allman, and M. J. McPhaul. Androgen increases androgen receptor protein while decreasing receptor mRNA in LNCap cells. Mol. Cell. Endocrinol. 76: 79-88, 1991.
18. Krotkiewski, M., P. Björntorp, L. Sjöström, and U. Smith. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. J. Clin. Invest. 72: 1150-1162, 1983.
19. Lacasa, D., B. Agli, M. Mur, J. P. Dausse, and Y. Giudicelli. Influence of ovarian status and regional fat distribution on protein kinase C in rat fat cells. J. Endocrinol. 140: 275-282, 1994.
20. Lacasa, D., E. Garcia, D. Henriot, B. Agli, and Y. Giudicelli. Site-related specificities of the control by androgenic status of adipogenesis and mitogen-activated protein kinase cascade/c-fos signaling pathways in rat preadipocytes. Endocrinology 138: 3181-3186, 1997.
21. Lacasa, D., M. Mur, B. Agli, and Y. Giudicelli. Protein kinase C in rat adipocytes is influenced by the androgenic status and the regional fat distribution. J. Endocrinol. 138: 493-501, 1993.
22. Lee, C., D. M. Sutkowski, J. A. Sensibar, D. Zelner, I. Kim, I. Amsel, N. Shaw, G. S. Prins, and J. M. Kozlowski. Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCap, by dihydrotestosterone. Endocrinology 136: 796-803, 1995.
23. Marin, P., L. Lönn, B. Andersson, B. Oden, L. Olbe, B. A. Bengtsson, and P. Björntorp. Assimilation of trigycerides in subcutaneous and intraabdominal adipose tissues in vivo in men: effects of testosterone. J. Clin. Endocrinol. Metab. 81: 1018-1022, 1996.
24. Menard, C. S., and R. E. Harlan. Up-regulation of androgen receptor immunoreactivity in the rat brain by androgenic-anabolic steroids. Brain Res. 622: 226-236, 1993.
25. Miller, L. K., J. G. Kral, G. W. Strains, and B. Zumoff. Androgen binding to ammonium sulfate precipitates of human adipose tissue cytosols. Steroids 55: 410-415, 1990.
26. Mizutani, T., Y. Nishikawa, H. Adachi, T. Enomoto, H. Ikegami, H. Kurachi, T. Nomura, and A. Miyake. Identification of estrogen receptors in human adipose tissue and adipocytes. J. Clin. Endocrinol. Metab. 78: 950-954, 1994.
27. Mora, G. R., G. S. Prins, and V. B. Mahesh. Autoregulation of androgen receptor protein and messenger RNA in rat ventral prostate is protein synthesis dependent. J. Steroid Biochem. Mol. Biol. 58: 539-549, 1996.
28. 2-adrenoreceptor protein and mRNA by a direct effect of androgens in white adipocytes. Biochem. Biophys. Res. Commun. 206: 112-118, 1995.
29. 2-receptor subtypes in the adrenergic control of lipolysis. Biochim. Biophys. Acta 731: 397-405, 1983.
30. Peiris, A. N., M. S. Sothman, R. G. Hoffman, M. I. Hensen, C. R. Wilson, A. B. Gustafson, and A. Kissebah. Adiposity, fat distribution and cardiovascular risk. Ann. Intern. Med. 110: 867-872, 1989.
31. Price, T. M., and S. N. O'Brien. Determination of estrogen receptor messenger ribonucleic acid (messenger RNA) and cytochrome-P450 aromatase messenger RNA Levels in adipocytes and adipose stromal cells by competitive polymerase chain reaction amplification. J. Clin. Endocrinol. Metab. 77: 1041-1045, 1993.
32. Rebuffé-Scrive, M., L. Enk, N. Crona, P. Lönnroth, L. Abrabamsson, U. Smith, and P. Björntorp. Fat cell metabolism in different regions in women: effect of menstrual cycle, pregnancy and lactation. J. Clin. Invest. 75: 1973-1976, 1985.
33. Rebuffé-Scrive, M., P. Lönnroth, P. Marin, C. Wesslau, P. Björntorp, and U. Smith. Regional adipose tissue metabolism in men and postmenopausal women. Int. J. Obes. 11: 347-355, 1987.
34. Rebuffé-Scrive, M., P. Marin, and P. Björntorp. Effect of testosterone on abdominal adipose tissue in men. Int. J. Obes. 15: 791-795, 1991.
35. Roncari, D. A. K., and R. L. R. Van. Promotion of human adipocyte precursor replication by 17-beta estradiol in culture. J. Clin. Invest. 62: 03-508, 1978.
36. Vague, J., J. M. Meignen, and J. F. Negrin. Effects of testosterone and estrogens on deltoid and trochanter adipocytes in two cases of transsexualism. Horm. Metab. Res. 16: 380-381, 1984.
37. Vornberger, W., G. Prins, N. A. Musto, and C. Suarez-Quian. Androgen receptor distribution in rat testis: new implications for androgen regulation of spermatogenesis. Endocrinology 134: 2307-2316, 1994.
38. Wahli, W., and M. Martinuzzo. Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression. FASEB J. 5: 2243-2249, 1991.
39. Wise, S., and H. Green. Participation of one isoenzyme of cytosolic glycero-P-dehydrogenase in adipose conversion of 3T3 cells. J. Biol. Chem. 254: 273-275, 1979.
40. Wolf, D. A., T. Herzinger, H. Hermeking, D. Blaschke, and W. Horz. Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen. Mol. Endocrinol. 7: 924-936, 1993.
41. Xu, X., G. De Pergola, and P. Björntorp. The effect of androgens on the regulation of lipolysis in adipose precursor cells. Endocrinology 126: 1229-1234, 1990.