-
1
-
-
0032579277
-
A novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinoma
-
Apergis GA, Crawford N, Ghosh D, Steppan CM, Vorachek WR, et al. 1998. A novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinoma. J. Biol. Chem. 273:2917-25
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2917-2925
-
-
Apergis, G.A.1
Crawford, N.2
Ghosh, D.3
Steppan, C.M.4
Vorachek, W.R.5
-
2
-
-
0027237596
-
Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
-
Azpiazu N, Frasch M. 1993. Tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 7:1325-40
-
(1993)
Genes Dev.
, vol.7
, pp. 1325-1340
-
-
Azpiazu, N.1
Frasch, M.2
-
3
-
-
0036696087
-
The genetics of congenital heart disease: A point in the revolution
-
Benson DW. 2002. The genetics of congenital heart disease: a point in the revolution. Cardiol. Clin. 20:385-94
-
(2002)
Cardiol. Clin.
, vol.20
, pp. 385-394
-
-
Benson, D.W.1
-
4
-
-
0028281469
-
The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome)
-
Basson CT, Cowley GS, Solomon SD, Weissman B, Poznanski AK, et al. 1994. The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome). N. Engl. J. Med. 330:885-91
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 885-891
-
-
Basson, C.T.1
Cowley, G.S.2
Solomon, S.D.3
Weissman, B.4
Poznanski, A.K.5
-
5
-
-
0032479573
-
Congenital heart disease caused by mutations in the transcription factor NKX2-5
-
Schott JJ, Benson DW, Basson CT, Pease W, Silberbach GM, et al. 1998. Congenital heart disease caused by mutations in the transcription factor NKX2-5. Science 281:108-11
-
(1998)
Science
, vol.281
, pp. 108-111
-
-
Schott, J.J.1
Benson, D.W.2
Basson, C.T.3
Pease, W.4
Silberbach, G.M.5
-
6
-
-
0027454207
-
Mapping a gene for familial situs abnormalities to human chromosome Xq24-q27.1
-
Casey B, Devoto M, Jones KL, Ballabio A. 1993. Mapping a gene for familial situs abnormalities to human chromosome Xq24-q27.1. Nat. Genet. 5:403-7
-
(1993)
Nat. Genet.
, vol.5
, pp. 403-407
-
-
Casey, B.1
Devoto, M.2
Jones, K.L.3
Ballabio, A.4
-
7
-
-
0030200833
-
Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors
-
Williamson JA, Bosher JM, Skinner A, Sheer D, Williams T, Hurst HC. 1996. Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors. Genomics 35:262-64
-
(1996)
Genomics
, vol.35
, pp. 262-264
-
-
Williamson, J.A.1
Bosher, J.M.2
Skinner, A.3
Sheer, D.4
Williams, T.5
Hurst, H.C.6
-
8
-
-
0033582940
-
GATA4 haploinsufficiency in patients with interstitial deletion of chromosome region 8p23.1 and congenital heart disease
-
Pehlivan T, Pober BR, Brueckner M, Garrett S, Slaugh R, et al. 1999. GATA4 haploinsufficiency in patients with interstitial deletion of chromosome region 8p23.1 and congenital heart disease. Am. J. Med. Genet. 83:201-6
-
(1999)
Am. J. Med. Genet.
, vol.83
, pp. 201-206
-
-
Pehlivan, T.1
Pober, B.R.2
Brueckner, M.3
Garrett, S.4
Slaugh, R.5
-
9
-
-
10744226877
-
Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot
-
Pizzuti A, Sarkozy A, Newton AL, Conti E, Flex E, et al. 2003. Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Hum. Mutat. 22:372-77
-
(2003)
Hum. Mutat.
, vol.22
, pp. 372-377
-
-
Pizzuti, A.1
Sarkozy, A.2
Newton, A.L.3
Conti, E.4
Flex, E.5
-
10
-
-
0033430230
-
Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways
-
Benson DW, Silberbach GM, Kavanaugh-McHugh A, Cottrill C, Zhang Y, et al. 1999. Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways. J. Clin. Invest. 104:1567-73
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1567-1573
-
-
Benson, D.W.1
Silberbach, G.M.2
Kavanaugh-McHugh, A.3
Cottrill, C.4
Zhang, Y.5
-
11
-
-
0035923555
-
NKX2.5 mutations in patients with tetralogy of fallot
-
Goldmuntz E, Geiger E, Benson DW. 2001. NKX2.5 mutations in patients with tetralogy of fallot. Circulation 104:2565-68
-
(2001)
Circulation
, vol.104
, pp. 2565-2568
-
-
Goldmuntz, E.1
Geiger, E.2
Benson, D.W.3
-
12
-
-
0036631483
-
Progressive AV-block and anomalous venous return among cardiac anomalies associated with two novel missense mutations in the CSX/NKX2-5 gene
-
Gutierrez-Roelens I, Sluysmans T, Gewillig M, Devriendt K, Vikkula M. 2002. Progressive AV-block and anomalous venous return among cardiac anomalies associated with two novel missense mutations in the CSX/NKX2-5 gene. Hum. Mutat. 20:75-76
-
(2002)
Hum. Mutat.
, vol.20
, pp. 75-76
-
-
Gutierrez-Roelens, I.1
Sluysmans, T.2
Gewillig, M.3
Devriendt, K.4
Vikkula, M.5
-
13
-
-
0036306830
-
Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease
-
Ikeda Y, Hiroi Y, Hosoda T, Utsunomiya T, Matsuo S, et al. 2002. Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease. Circ. J. 66:561-63
-
(2002)
Circ. J.
, vol.66
, pp. 561-563
-
-
Ikeda, Y.1
Hiroi, Y.2
Hosoda, T.3
Utsunomiya, T.4
Matsuo, S.5
-
14
-
-
0033912859
-
Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease
-
Kasahara H, Lee B, Schott JJ, Benson DW, Seidman JG, et al. 2000. Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease. J. Clin. Invest. 106:299-308
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 299-308
-
-
Kasahara, H.1
Lee, B.2
Schott, J.J.3
Benson, D.W.4
Seidman, J.G.5
-
15
-
-
0242636701
-
NKX2.5 mutations in patients with congenital heart disease
-
McElhinney DB, Geiger E, Blinder J, Benson DW, Goldmuntz E. 2003. NKX2.5 mutations in patients with congenital heart disease. J. Am. Coll. Cardiol. 42:1650-55
-
(2003)
J. Am. Coll. Cardiol.
, vol.42
, pp. 1650-1655
-
-
McElhinney, D.B.1
Geiger, E.2
Blinder, J.3
Benson, D.W.4
Goldmuntz, E.5
-
16
-
-
0036848609
-
Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD
-
Watanabe Y, Benson DW, Yano S, Akagi T, Yoshino M, Murray JC. 2002. Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD. J. Med. Genet. 39:807-11
-
(2002)
J. Med. Genet.
, vol.39
, pp. 807-811
-
-
Watanabe, Y.1
Benson, D.W.2
Yano, S.3
Akagi, T.4
Yoshino, M.5
Murray, J.C.6
-
17
-
-
4444223413
-
Biochemical analyses of eight NKX2.5 homeodomain missense mutations causing atrioventricular block and cardiac anomalies
-
Kasahara H, Benson DW. 2004. Biochemical analyses of eight NKX2.5 homeodomain missense mutations causing atrioventricular block and cardiac anomalies. Cardiovasc. Res. 64:40-51
-
(2004)
Cardiovasc. Res.
, vol.64
, pp. 40-51
-
-
Kasahara, H.1
Benson, D.W.2
-
18
-
-
4844228952
-
Genetics of atrioventricular conduction disease in humans
-
Benson DW. 2004. Genetics of atrioventricular conduction disease in humans. Anat. Rec. 280A:934-39
-
(2004)
Anat. Rec.
, vol.280 A
, pp. 934-939
-
-
Benson, D.W.1
-
19
-
-
0043267988
-
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
-
Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, et al. 2003. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 424:443-47
-
(2003)
Nature
, vol.424
, pp. 443-447
-
-
Garg, V.1
Kathiriya, I.S.2
Barnes, R.3
Schluterman, M.K.4
King, I.N.5
-
20
-
-
20944442976
-
Phenotypes with GATA4 or NKX2.5 mutations in familial atrial septal defect
-
Hirayama-Yamada K, Kamisago M, Akimoto K, Aotsuka H, Nakamura Y, et al. 2005. Phenotypes with GATA4 or NKX2.5 mutations in familial atrial septal defect. Am. J. Med. Genet. A 135:47-52
-
(2005)
Am. J. Med. Genet. A
, vol.135
, pp. 47-52
-
-
Hirayama-Yamada, K.1
Kamisago, M.2
Akimoto, K.3
Aotsuka, H.4
Nakamura, Y.5
-
21
-
-
1842413728
-
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
-
Li QY, Newbury-Ecob RA, Terrett JA, Wilson DI, Curtis AR, et al. 1997. Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat. Genet. 15:21-29
-
(1997)
Nat. Genet.
, vol.15
, pp. 21-29
-
-
Li, Q.Y.1
Newbury-Ecob, R.A.2
Terrett, J.A.3
Wilson, D.I.4
Curtis, A.R.5
-
22
-
-
0030636780
-
Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome
-
Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, et al. 1997. Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nat. Genet. 15:30-35.
-
(1997)
Nat. Genet.
, vol.15
, pp. 30-35
-
-
Basson, C.T.1
Bachinsky, D.R.2
Lin, R.C.3
Levi, T.4
Elkins, J.A.5
-
23
-
-
0030900347
-
-
Erratum
-
Erratum. 1997. Nat. Genet. 15:411
-
(1997)
Nat. Genet.
, vol.15
, pp. 411
-
-
-
24
-
-
0036889943
-
Current advances in Holt-Oram syndrome
-
Huang T. 2002. Current advances in Holt-Oram syndrome. Curr. Opin. Pediatr. 14:691-95
-
(2002)
Curr. Opin. Pediatr.
, vol.14
, pp. 691-695
-
-
Huang, T.1
-
25
-
-
0037665257
-
Holt-Oram syndrome: A new mutation in the TBX5 gene in two unrelated families
-
Gruenauer-Kloevekorn C, Froster UG. 2003. Holt-Oram syndrome: a new mutation in the TBX5 gene in two unrelated families. Ann. Genet. 46:19-23
-
(2003)
Ann. Genet.
, vol.46
, pp. 19-23
-
-
Gruenauer-Kloevekorn, C.1
Froster, U.G.2
-
26
-
-
9244261087
-
The genetic contribution to congenital heart disease
-
Goldmuntz E. 2004. The genetic contribution to congenital heart disease. Pediatr. Clin. North Am. 51:1721-37
-
(2004)
Pediatr. Clin. North Am.
, vol.51
, pp. 1721-1737
-
-
Goldmuntz, E.1
-
27
-
-
0023625914
-
X-linked laterality sequence: Situs inversus, complex cardiac defects, splenic defects
-
Mathias RS, Lacro RV, Jones KL. 1987. X-linked laterality sequence: situs inversus, complex cardiac defects, splenic defects. Am. J. Med. Genet. 28:111-16
-
(1987)
Am. J. Med. Genet.
, vol.28
, pp. 111-116
-
-
Mathias, R.S.1
Lacro, R.V.2
Jones, K.L.3
-
28
-
-
16944362226
-
A submicroscopic deletion in Xq26 associated with familial situs ambiguus
-
Ferrero GB, Gebbia M, Pilia G, Witte D, Peier A, et al. 1997. A submicroscopic deletion in Xq26 associated with familial situs ambiguus. Am. J. Hum. Genet. 61:395-401
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 395-401
-
-
Ferrero, G.B.1
Gebbia, M.2
Pilia, G.3
Witte, D.4
Peier, A.5
-
29
-
-
16944364984
-
X-linked situs abnormalities result from mutations in ZIC3
-
Gebbia M, Ferrero GB, Pilia G, Bassi MT, Aylsworth A, et al. 1997. X-linked situs abnormalities result from mutations in ZIC3. Nat. Genet. 17:305-8
-
(1997)
Nat. Genet.
, vol.17
, pp. 305-308
-
-
Gebbia, M.1
Ferrero, G.B.2
Pilia, G.3
Bassi, M.T.4
Aylsworth, A.5
-
30
-
-
0036337344
-
A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice
-
Purandare SM, Ware SM, Kwan KM, Gebbia M, Bassi MT, et al. 2002. A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice. Development 129:2293-302
-
(2002)
Development
, vol.129
, pp. 2293-2302
-
-
Purandare, S.M.1
Ware, S.M.2
Kwan, K.M.3
Gebbia, M.4
Bassi, M.T.5
-
31
-
-
0347003520
-
Identification and functional analysis of ZIC3 mutations in heterotaxy and related congenital heart defects
-
Ware SM, Peng J, Zhu L, Fernbach S, Colicos S, et al. 2004. Identification and functional analysis of ZIC3 mutations in heterotaxy and related congenital heart defects. Am. J. Hum. Genet. 74:93-105
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 93-105
-
-
Ware, S.M.1
Peng, J.2
Zhu, L.3
Fernbach, S.4
Colicos, S.5
-
32
-
-
0029119180
-
Cloning and characterization of a second AP-2 transcription factor: AP-2 beta
-
Moser M, Imhof A, Pscherer A, Bauer R, Amselgruber W, et al. 1995. Cloning and characterization of a second AP-2 transcription factor: AP-2 beta. Development 121:2779-88
-
(1995)
Development
, vol.121
, pp. 2779-2788
-
-
Moser, M.1
Imhof, A.2
Pscherer, A.3
Bauer, R.4
Amselgruber, W.5
-
33
-
-
0033564061
-
Char syndrome, an inherited disorder with patent ductus arteriosus, maps to chromosome 6p12-p21
-
Satoda M, Pierpont ME, Diaz GA, Bornemeier RA, Gelb BD. 1999. Char syndrome, an inherited disorder with patent ductus arteriosus, maps to chromosome 6p12-p21. Circulation 99:3036-42
-
(1999)
Circulation
, vol.99
, pp. 3036-3042
-
-
Satoda, M.1
Pierpont, M.E.2
Diaz, G.A.3
Bornemeier, R.A.4
Gelb, B.D.5
-
34
-
-
0034022637
-
Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus
-
Satoda M, Zhao F, Diaz GA, Burn J, Goodship J, et al. 2000. Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus. Nat. Genet. 25:42-46
-
(2000)
Nat. Genet.
, vol.25
, pp. 42-46
-
-
Satoda, M.1
Zhao, F.2
Diaz, G.A.3
Burn, J.4
Goodship, J.5
-
35
-
-
20044365972
-
Syndromic patent ductus arteriosus: Evidence for haploinsufficient TFAP2B mutations and identification of a linked sleep disorder
-
Mani A, Radhakrishnan J, Farhi A, Carew KS, Warnes CA, et al. 2005. Syndromic patent ductus arteriosus: evidence for haploinsufficient TFAP2B mutations and identification of a linked sleep disorder. Proc. Natl Acad. Sci. USA 102:2975-79
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 2975-2979
-
-
Mani, A.1
Radhakrishnan, J.2
Farhi, A.3
Carew, K.S.4
Warnes, C.A.5
-
36
-
-
0034836484
-
Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation
-
Zhao F, Weismann CG, Satoda M, Pierpont ME, Sweeney E, et al. 2001. Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation. Am. J. Hum. Genet. 69:695-703
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 695-703
-
-
Zhao, F.1
Weismann, C.G.2
Satoda, M.3
Pierpont, M.E.4
Sweeney, E.5
-
37
-
-
2442656306
-
DiGeorge syndrome: An update
-
Baldini A. 2004. DiGeorge syndrome: an update. Curr. Opin. Cardiol. 19:201-4
-
(2004)
Curr. Opin. Cardiol.
, vol.19
, pp. 201-204
-
-
Baldini, A.1
-
38
-
-
0033598389
-
Congenital heart disease in mice deficient for the DiGeorge syndrome region
-
Lindsay EA, Botta A, Jurecic V, Carattini-Rivera S, Cheah YC, et al. 1999. Congenital heart disease in mice deficient for the DiGeorge syndrome region. Nature 401:379-83
-
(1999)
Nature
, vol.401
, pp. 379-383
-
-
Lindsay, E.A.1
Botta, A.2
Jurecic, V.3
Carattini-Rivera, S.4
Cheah, Y.C.5
-
39
-
-
17744395906
-
TBX1 is responsible for cardiovascular defects in velo-cardiofacial/ DiGeorge syndrome
-
Merscher S, Funke B, Epstein JA, Heyer J, Puech A, et al. 2001. TBX1 is responsible for cardiovascular defects in velo-cardiofacial/DiGeorge syndrome. Cell 104:619-29
-
(2001)
Cell
, vol.104
, pp. 619-629
-
-
Merscher, S.1
Funke, B.2
Epstein, J.A.3
Heyer, J.4
Puech, A.5
-
40
-
-
0035263599
-
Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice
-
Lindsay EA, Vitelli F, Su H, Morishima M, Huynh T, et al. 2001. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 410:97-101
-
(2001)
Nature
, vol.410
, pp. 97-101
-
-
Lindsay, E.A.1
Vitelli, F.2
Su, H.3
Morishima, M.4
Huynh, T.5
-
41
-
-
0035098557
-
DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
-
Jerome LA, Papaioannou VE. 2001. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1. Nat. Genet. 27:286-91
-
(2001)
Nat. Genet.
, vol.27
, pp. 286-291
-
-
Jerome, L.A.1
Papaioannou, V.E.2
-
42
-
-
10744223651
-
Role of TBX1 in human del22q11.2 syndrome
-
Yagi H, Furutani Y, Hamada H, Sasaki T, Asakawa S, et al. 2003. Role of TBX1 in human del22q11.2 syndrome. Lancet 362:1366-73
-
(2003)
Lancet
, vol.362
, pp. 1366-1373
-
-
Yagi, H.1
Furutani, Y.2
Hamada, H.3
Sasaki, T.4
Asakawa, S.5
-
43
-
-
17344369067
-
Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation
-
Stoller JZ, Epstein JA. 2005. Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation. Hum. Mol. Genet. 14:885-92
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 885-892
-
-
Stoller, J.Z.1
Epstein, J.A.2
-
44
-
-
0035653927
-
Mutation analysis of TBX1 in non-deleted patients with features of DGS/VCFS or isolated cardiovascular defects
-
Gong W, Gottlieb S, Collins J, Blescia A, Dietz H, et al. 2001. Mutation analysis of TBX1 in non-deleted patients with features of DGS/VCFS or isolated cardiovascular defects. J. Med. Genet. 38:E45
-
(2001)
J. Med. Genet.
, vol.38
-
-
Gong, W.1
Gottlieb, S.2
Collins, J.3
Blescia, A.4
Dietz, H.5
-
45
-
-
0033514433
-
Molecular cloning of FOG-2: A modulator of transcription factor GATA-4 in cardiomyocytes
-
Svensson EC, Tufts RL, Polk CE, Leiden JM. 1999. Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proc. Natl. Acad. Sci. USA 96:956-61
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 956-961
-
-
Svensson, E.C.1
Tufts, R.L.2
Polk, C.E.3
Leiden, J.M.4
-
46
-
-
0034648772
-
A genetic blueprint for cardiac development
-
Srivastava D, Olson EN. 2000. A genetic blueprint for cardiac development. Nature 407:221-26
-
(2000)
Nature
, vol.407
, pp. 221-226
-
-
Srivastava, D.1
Olson, E.N.2
-
48
-
-
0036195078
-
Wherefore heart thou? Embryonic origins of cardiogenic mesoderm
-
Yutzey KE, Kirby ML. 2002. Wherefore heart thou? Embryonic origins of cardiogenic mesoderm. Dev. Dyn. 223:307-20
-
(2002)
Dev. Dyn.
, vol.223
, pp. 307-320
-
-
Yutzey, K.E.1
Kirby, M.L.2
-
49
-
-
0037155776
-
Transcriptional regulation of vertebrate cardiac morphogenesis
-
Bruneau BG. 2002. Transcriptional regulation of vertebrate cardiac morphogenesis. Circ. Res. 90:509-19
-
(2002)
Circ. Res.
, vol.90
, pp. 509-519
-
-
Bruneau, B.G.1
-
50
-
-
0038485530
-
Heart development: Molecular insights into cardiac specification and early morphogenesis
-
Brand T. 2003. Heart development: molecular insights into cardiac specification and early morphogenesis. Dev. Biol. 258:1-19
-
(2003)
Dev. Biol.
, vol.258
, pp. 1-19
-
-
Brand, T.1
-
51
-
-
0027282774
-
The gene tinman is required for specification of the heart and visceral muscles in Drosophila
-
Bodmer R. 1993. The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118:719-29
-
(1993)
Development
, vol.118
, pp. 719-729
-
-
Bodmer, R.1
-
52
-
-
0000342273
-
Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements
-
Chen CY, Croissant J, Majesky M, Topouzis S, McQuinn T, et al. 1996. Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements. Dev. Genet. 19:119-30
-
(1996)
Dev. Genet.
, vol.19
, pp. 119-130
-
-
Chen, C.Y.1
Croissant, J.2
Majesky, M.3
Topouzis, S.4
McQuinn, T.5
-
53
-
-
0031647381
-
Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
-
Fu Y, Yan W, Mohun TJ, Evans SM. 1998. Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner. Development 125:4439-49
-
(1998)
Development
, vol.125
, pp. 4439-4449
-
-
Fu, Y.1
Yan, W.2
Mohun, T.J.3
Evans, S.M.4
-
54
-
-
0032380010
-
Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5
-
Grow MW, Krieg PA. 1998. Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5. Dev. Biol. 204:187-96
-
(1998)
Dev. Biol.
, vol.204
, pp. 187-196
-
-
Grow, M.W.1
Krieg, P.A.2
-
55
-
-
0027383023
-
Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
-
Lints TJ, Parsons LM, Hartley L, Lyons I, Harvey RP. 1993. Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119:419-31
-
(1993)
Development
, vol.119
, pp. 419-431
-
-
Lints, T.J.1
Parsons, L.M.2
Hartley, L.3
Lyons, I.4
Harvey, R.P.5
-
56
-
-
0029090829
-
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
-
Lyons I, Parsons LM, Hartley L, Li R, Andrews JE, et al. 1995. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev. 9:1654-66
-
(1995)
Genes Dev.
, vol.9
, pp. 1654-1666
-
-
Lyons, I.1
Parsons, L.M.2
Hartley, L.3
Li, R.4
Andrews, J.E.5
-
57
-
-
0344428124
-
Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5
-
Tanaka M, Wechsler SB, Lee IW, Yamasaki N, Lawitts JA, Izumo S. 1999. Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5. Development 126:1439-50
-
(1999)
Development
, vol.126
, pp. 1439-1450
-
-
Tanaka, M.1
Wechsler, S.B.2
Lee, I.W.3
Yamasaki, N.4
Lawitts, J.A.5
Izumo, S.6
-
58
-
-
0027937398
-
Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development
-
Heikinheimo M, Scandrett JM, Wilson DB. 1994. Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development. Dev. Biol. 164:361-73
-
(1994)
Dev. Biol.
, vol.164
, pp. 361-373
-
-
Heikinheimo, M.1
Scandrett, J.M.2
Wilson, D.B.3
-
59
-
-
0342658137
-
Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development
-
Chapman DL, Garvey N, Hancock S, Alexiou M, Agulnik SI, et al. 1996. Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev. Dyn. 206:379-90
-
(1996)
Dev. Dyn.
, vol.206
, pp. 379-390
-
-
Chapman, D.L.1
Garvey, N.2
Hancock, S.3
Alexiou, M.4
Agulnik, S.I.5
-
60
-
-
4544277159
-
The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system
-
Moskowitz IP, Pizard A, Patel VV, Bruneau BG, Kim JB, et al. 2004. The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system. Development 131:4107-16
-
(2004)
Development
, vol.131
, pp. 4107-4116
-
-
Moskowitz, I.P.1
Pizard, A.2
Patel, V.V.3
Bruneau, B.G.4
Kim, J.B.5
-
61
-
-
0035386434
-
Elevated expression of Nkx-2.5 in developing myocardial conduction cells
-
Thomas PS, Kasahara H, Edmonson AM, Izumo S, Yacoub MH, et al. 2001. Elevated expression of Nkx-2.5 in developing myocardial conduction cells. Anat. Rec. 263:307-13
-
(2001)
Anat. Rec.
, vol.263
, pp. 307-313
-
-
Thomas, P.S.1
Kasahara, H.2
Edmonson, A.M.3
Izumo, S.4
Yacoub, M.H.5
-
62
-
-
11144357335
-
Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block
-
Pashmforoush M, Lu JT, Chen H, Amand TS, Kondo R, et al. 2004. Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell 117:373-86
-
(2004)
Cell
, vol.117
, pp. 373-386
-
-
Pashmforoush, M.1
Lu, J.T.2
Chen, H.3
Amand, T.S.4
Kondo, R.5
-
63
-
-
0030996908
-
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
-
Molkentin JD, Lin Q, Duncan SA, Olson EN. 1997. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 11:1061-72
-
(1997)
Genes Dev.
, vol.11
, pp. 1061-1072
-
-
Molkentin, J.D.1
Lin, Q.2
Duncan, S.A.3
Olson, E.N.4
-
64
-
-
0030916211
-
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
-
Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, et al. 1997. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 11:1048-60
-
(1997)
Genes Dev.
, vol.11
, pp. 1048-1060
-
-
Kuo, C.T.1
Morrisey, E.E.2
Anandappa, R.3
Sigrist, K.4
Lu, M.M.5
-
65
-
-
17944378083
-
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
-
Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, et al. 2001. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 106:709-21
-
(2001)
Cell
, vol.106
, pp. 709-721
-
-
Bruneau, B.G.1
Nemer, G.2
Schmitt, J.P.3
Charron, F.4
Robitaille, L.5
-
66
-
-
0034234753
-
Ventricular expression of tbx5 inhibits normal heart chamber development
-
Liberatore CM, Searcy-Schrick RD, Yutzey KE. 2000. Ventricular expression of tbx5 inhibits normal heart chamber development. Dev. Biol. 223:169-80
-
(2000)
Dev. Biol.
, vol.223
, pp. 169-180
-
-
Liberatore, C.M.1
Searcy-Schrick, R.D.2
Yutzey, K.E.3
-
67
-
-
0034634279
-
Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5
-
Biben C, Weber R, Kesteven S, Stanley E, McDonald L, et al. 2000. Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5. Circ. Res. 87:888-95
-
(2000)
Circ. Res.
, vol.87
, pp. 888-895
-
-
Biben, C.1
Weber, R.2
Kesteven, S.3
Stanley, E.4
McDonald, L.5
-
68
-
-
0034947445
-
Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein
-
Kasahara H, Wakimoto H, Liu M, Maguire CT, Converso KL, et al. 2001. Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein. J. Clin. Invest. 108:189-201
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 189-201
-
-
Kasahara, H.1
Wakimoto, H.2
Liu, M.3
Maguire, C.T.4
Converso, K.L.5
-
69
-
-
0035996734
-
Developmentally modulated cardiac conduction failure in transgenic mice with fetal or postnatal overexpression of DNA non-binding mutant Nkx2.5
-
Wakimoto H, Kasahara H, Maguire CT, Izumo S, Berul CI. 2002. Developmentally modulated cardiac conduction failure in transgenic mice with fetal or postnatal overexpression of DNA non-binding mutant Nkx2.5. J. Cardiovasc. Electrophysiol. 13:682-88
-
(2002)
J. Cardiovasc. Electrophysiol.
, vol.13
, pp. 682-688
-
-
Wakimoto, H.1
Kasahara, H.2
Maguire, C.T.3
Izumo, S.4
Berul, C.I.5
-
70
-
-
0344394995
-
Cardiac electrophysiological phenotypes in postnatal expression of Nkx2.5 transgenic mice
-
Wakimoto H, Kasahara H, Maguire CT, Moskowitz IP, Izumo S, Berul CI. 2003. Cardiac electrophysiological phenotypes in postnatal expression of Nkx2.5 transgenic mice. Genesis 37:144-50
-
(2003)
Genesis
, vol.37
, pp. 144-150
-
-
Wakimoto, H.1
Kasahara, H.2
Maguire, C.T.3
Moskowitz, I.P.4
Izumo, S.5
Berul, C.I.6
-
71
-
-
0037350193
-
Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes
-
Kasahara H, Ueyama T, Wakimoto H, Liu MK, Maguire CT, et al. 2003. Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes. J. Mol. Cell. Cardiol. 35:243-56
-
(2003)
J. Mol. Cell. Cardiol.
, vol.35
, pp. 243-256
-
-
Kasahara, H.1
Ueyama, T.2
Wakimoto, H.3
Liu, M.K.4
Maguire, C.T.5
-
72
-
-
4644358238
-
GATA4 is a dosage-sensitive regulator of cardiac morphogenesis
-
Pu WT, Ishiwata T, Juraszek AL, Ma Q, Izumo S. 2004. GATA4 is a dosage-sensitive regulator of cardiac morphogenesis. Dev. Biol. 275:235-44
-
(2004)
Dev. Biol.
, vol.275
, pp. 235-244
-
-
Pu, W.T.1
Ishiwata, T.2
Juraszek, A.L.3
Ma, Q.4
Izumo, S.5
-
73
-
-
2442624606
-
Differential expression and function of Tbx5 and Tbx20 in cardiac development
-
Plageman TF Jr, Yutzey KE. 2004. Differential expression and function of Tbx5 and Tbx20 in cardiac development. J. Biol. Chem. 279:19026-34
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19026-19034
-
-
Plageman Jr., T.F.1
Yutzey, K.E.2
-
74
-
-
0034931034
-
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
-
Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, et al. 2001. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat. Genet. 28:276-80
-
(2001)
Nat. Genet.
, vol.28
, pp. 276-280
-
-
Hiroi, Y.1
Kudoh, S.2
Monzen, K.3
Ikeda, Y.4
Yazaki, Y.5
-
75
-
-
0031568805
-
The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation
-
Nagai T, Aruga J, Takada S, Gunther T, Sporle R, et al. 1997. The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation. Dev. Biol. 182:299-313
-
(1997)
Dev. Biol.
, vol.182
, pp. 299-313
-
-
Nagai, T.1
Aruga, J.2
Takada, S.3
Gunther, T.4
Sporle, R.5
-
77
-
-
0033575364
-
Differences in left-right axis pathways in mouse and chick: Functions of FGF8 and SHH
-
Meyers EN, Martin GR. 1999. Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH. Science 285:403-6
-
(1999)
Science
, vol.285
, pp. 403-406
-
-
Meyers, E.N.1
Martin, G.R.2
-
79
-
-
0034839927
-
Conotruncal myocardium arises from a secondary heart field
-
Waldo KL, Kumiski DH, Wallis KT, Stadt HA, Hutson MR, et al. 2001. Conotruncal myocardium arises from a secondary heart field. Development 128:3179-88
-
(2001)
Development
, vol.128
, pp. 3179-3188
-
-
Waldo, K.L.1
Kumiski, D.H.2
Wallis, K.T.3
Stadt, H.A.4
Hutson, M.R.5
-
80
-
-
0035477641
-
The outflow tract of the heart is recruited from a novel heart-forming field
-
Mjaatvedt CH, Nakaoka T, Moreno-Rodriguez R, Norris RA, Kern MJ, et al. 2001. The outflow tract of the heart is recruited from a novel heart-forming field. Dev. Biol. 238:97-109
-
(2001)
Dev. Biol.
, vol.238
, pp. 97-109
-
-
Mjaatvedt, C.H.1
Nakaoka, T.2
Moreno-Rodriguez, R.3
Norris, R.A.4
Kern, M.J.5
-
81
-
-
0029142767
-
Neural crest and cardiovascular patterning
-
Kirby ML, Waldo KL. 1995. Neural crest and cardiovascular patterning. Circ. Res. 77:211-15
-
(1995)
Circ. Res.
, vol.77
, pp. 211-215
-
-
Kirby, M.L.1
Waldo, K.L.2
-
82
-
-
15444347159
-
Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta
-
Moser M, Pscherer A, Roth C, Becker J, Mucher G, et al. 1997. Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta. Genes Dev. 11:1938-48
-
(1997)
Genes Dev.
, vol.11
, pp. 1938-1948
-
-
Moser, M.1
Pscherer, A.2
Roth, C.3
Becker, J.4
Mucher, G.5
-
83
-
-
0034445182
-
Molecular determinants of atrial and ventricular septal defects and patent ductus arteriosus
-
Vaughan CJ, Basson CT. 2000. Molecular determinants of atrial and ventricular septal defects and patent ductus arteriosus. Am. J. Med. Genet. 97:304-9
-
(2000)
Am. J. Med. Genet.
, vol.97
, pp. 304-309
-
-
Vaughan, C.J.1
Basson, C.T.2
-
84
-
-
0036797067
-
A genetic link between Tbx1 and fibroblast growth factor signaling
-
Vitelli F, Taddei I, Morishima M, Meyers EN, Lindsay EA, Baldini A. 2002. A genetic link between Tbx1 and fibroblast growth factor signaling. Development 129:4605-11
-
(2002)
Development
, vol.129
, pp. 4605-4611
-
-
Vitelli, F.1
Taddei, I.2
Morishima, M.3
Meyers, E.N.4
Lindsay, E.A.5
Baldini, A.6
-
85
-
-
0141458167
-
Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome
-
Yamagishi H, Srivastava D. 2003. Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome. Trends Mol. Med. 9:383-89
-
(2003)
Trends Mol. Med.
, vol.9
, pp. 383-389
-
-
Yamagishi, H.1
Srivastava, D.2
-
86
-
-
0031215021
-
Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene
-
Chieffo C, Garvey N, Gong W, Roe B, Zhang G, et al. 1997. Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene. Genomics 43:267-77
-
(1997)
Genomics
, vol.43
, pp. 267-277
-
-
Chieffo, C.1
Garvey, N.2
Gong, W.3
Roe, B.4
Zhang, G.5
-
87
-
-
0034963495
-
Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development
-
Garg V, Yamagishi C, Hu T, Kathiriya IS, Yamagishi H, Srivastava D. 2001. Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Dev. Biol. 235:62-73
-
(2001)
Dev. Biol.
, vol.235
, pp. 62-73
-
-
Garg, V.1
Yamagishi, C.2
Hu, T.3
Kathiriya, I.S.4
Yamagishi, H.5
Srivastava, D.6
-
88
-
-
1642402120
-
The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer
-
Brown CO III, Chi X, Garcia-Gras E, Shirai M, Feng XH, Schwartz RJ. 2004. The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J. Biol. Chem. 279:10659-69
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10659-10669
-
-
Brown III, C.O.1
Chi, X.2
Garcia-Gras, E.3
Shirai, M.4
Feng, X.H.5
Schwartz, R.J.6
-
89
-
-
0034705318
-
FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium
-
Tevosian SG, Deconinck AE, Tanaka M, Schinke M, Litovsky SH, et al. 2000. FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium. Cell 101:729-39
-
(2000)
Cell
, vol.101
, pp. 729-739
-
-
Tevosian, S.G.1
Deconinck, A.E.2
Tanaka, M.3
Schinke, M.4
Litovsky, S.H.5
-
91
-
-
0034617095
-
A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription
-
Svensson EC, Huggins GS, Dardik FB, Polk CE, Leiden JM. 2000. A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription. J. Biol. Chem. 275:20762-6
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20762-20766
-
-
Svensson, E.C.1
Huggins, G.S.2
Dardik, F.B.3
Polk, C.E.4
Leiden, J.M.5
-
92
-
-
0033945862
-
A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2
-
Svensson EC, Huggins GS, Lin H, Clendenin C, Jiang F, et al. 2000. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Nat. Genet. 25:353-56
-
(2000)
Nat. Genet.
, vol.25
, pp. 353-356
-
-
Svensson, E.C.1
Huggins, G.S.2
Lin, H.3
Clendenin, C.4
Jiang, F.5
-
93
-
-
0345516018
-
Epicardium-derived cells contribute a novel population to the myocardial wall and the atrioventricular cushions
-
Gittenberger-de Groot AC, Vrancken Peeters MP, Mentink MM, Gourdie RG, Poelmann RE. 1998. Epicardium-derived cells contribute a novel population to the myocardial wall and the atrioventricular cushions. Circ. Res. 82:1043-52
-
(1998)
Circ. Res.
, vol.82
, pp. 1043-1052
-
-
Gittenberger-De Groot, A.C.1
Vrancken Peeters, M.P.2
Mentink, M.M.3
Gourdie, R.G.4
Poelmann, R.E.5
-
94
-
-
0034711517
-
Epicardial outgrowth inhibition leads to compensatory mesothelial outflow tract collar and abnormal cardiac septation and coronary formation
-
Gittenberger-de Groot AC, Vrancken Peeters MP, Bergwerff M, Mentink MM, Poelmann RE. 2000. Epicardial outgrowth inhibition leads to compensatory mesothelial outflow tract collar and abnormal cardiac septation and coronary formation. Circ. Res. 87:969-71
-
(2000)
Circ. Res.
, vol.87
, pp. 969-971
-
-
Gittenberger-De Groot, A.C.1
Vrancken Peeters, M.P.2
Bergwerff, M.3
Mentink, M.M.4
Poelmann, R.E.5
-
95
-
-
0033551786
-
FOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation
-
Holmes M, Turner J, Fox A, Chisholm O, Crossley M, Chong B. 1999. hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation. J. Biol. Chem. 274:23491-98
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23491-23498
-
-
Holmes, M.1
Turner, J.2
Fox, A.3
Chisholm, O.4
Crossley, M.5
Chong, B.6
-
96
-
-
0033049126
-
FOG-2, a heart- and brain-enriched cofactor for GATA transcription factors
-
Lu JR, McKinsey TA, Xu H, Wang DZ, Richardson JA, Olson EN. 1999. FOG-2, a heart- and brain-enriched cofactor for GATA transcription factors. Mol. Cell. Biol. 19:4495-502
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4495-4502
-
-
Lu, J.R.1
McKinsey, T.A.2
Xu, H.3
Wang, D.Z.4
Richardson, J.A.5
Olson, E.N.6
-
97
-
-
0035312839
-
Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors
-
Crispino JD, Lodish MB, Thurberg BL, Litovsky SH, Collins T, et al. 2001. Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev. 15:839-44
-
(2001)
Genes Dev.
, vol.15
, pp. 839-844
-
-
Crispino, J.D.1
Lodish, M.B.2
Thurberg, B.L.3
Litovsky, S.H.4
Collins, T.5
-
98
-
-
0028148114
-
Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain
-
Damante G, Fabbro D, Pellizzari L, Civitareale D, Guazzi S, et al. 1994. Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain. Nucleic Acids Res. 22:3075-83
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3075-3083
-
-
Damante, G.1
Fabbro, D.2
Pellizzari, L.3
Civitareale, D.4
Guazzi, S.5
-
99
-
-
0030916275
-
Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: Basis of binding specificity
-
Gruschus JM, Tsao DH, Wang LH, Nirenberg M, Ferretti JA. 1997. Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry 36:5372-80
-
(1997)
Biochemistry
, vol.36
, pp. 5372-5380
-
-
Gruschus, J.M.1
Tsao, D.H.2
Wang, L.H.3
Nirenberg, M.4
Ferretti, J.A.5
-
100
-
-
0030587603
-
NK-2 homeobox genes and heart development
-
Harvey RP. 1996. NK-2 homeobox genes and heart development. Dev. Biol. 178:203-16
-
(1996)
Dev. Biol.
, vol.178
, pp. 203-216
-
-
Harvey, R.P.1
-
101
-
-
0029972345
-
Molecular cloning and characterization of human cardiac homeobox gene CSX1
-
Shiojima I, Komuro I, Mizuno T, Aikawa R, Akazawa H, et al. 1996. Molecular cloning and characterization of human cardiac homeobox gene CSX1. Circ. Res. 79:920-29
-
(1996)
Circ. Res.
, vol.79
, pp. 920-929
-
-
Shiojima, I.1
Komuro, I.2
Mizuno, T.3
Aikawa, R.4
Akazawa, H.5
-
102
-
-
0035895925
-
Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein
-
Kasahara H, Usheva A, Ueyama T, Aoki H, Horikoshi N, Izumo S. 2001. Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein. J. Biol. Chem. 276:4570-80
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4570-4580
-
-
Kasahara, H.1
Usheva, A.2
Ueyama, T.3
Aoki, H.4
Horikoshi, N.5
Izumo, S.6
-
103
-
-
0031844382
-
The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
-
Lee Y, Shioi T, Kasahara H, Jobe SM, Wiese RJ, et al. 1998. The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol. Cell. Biol. 18:3120-29
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3120-3129
-
-
Lee, Y.1
Shioi, T.2
Kasahara, H.3
Jobe, S.M.4
Wiese, R.J.5
-
104
-
-
0141615095
-
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart
-
Stennard FA, Costa MW, Elliott DA, Rankin S, Haast SJ, et al. 2003. Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev. Biol. 262:206-24
-
(2003)
Dev. Biol.
, vol.262
, pp. 206-224
-
-
Stennard, F.A.1
Costa, M.W.2
Elliott, D.A.3
Rankin, S.4
Haast, S.J.5
-
105
-
-
11144236620
-
Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C
-
Zang MX, Li Y, Xue LX, Jia HT, Jing H. 2004. Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C. J. Cell. Biochem. 93:1255-66
-
(2004)
J. Cell. Biochem.
, vol.93
, pp. 1255-1266
-
-
Zang, M.X.1
Li, Y.2
Xue, L.X.3
Jia, H.T.4
Jing, H.5
-
106
-
-
0034634624
-
Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease
-
Zhu W, Shiojima I, Hiroi Y, Zou Y, Akazawa H, et al. 2000. Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease. J. Biol. Chem. 275:35291-96
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35291-35296
-
-
Zhu, W.1
Shiojima, I.2
Hiroi, Y.3
Zou, Y.4
Akazawa, H.5
-
107
-
-
0029779002
-
The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium
-
Durocher D, Chen CY, Ardati A, Schwartz RJ, Nemer M. 1996. The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium. Mol. Cell. Biol. 16:4648-55
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4648-4655
-
-
Durocher, D.1
Chen, C.Y.2
Ardati, A.3
Schwartz, R.J.4
Nemer, M.5
-
108
-
-
0033583178
-
Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4
-
Shiojima I, Komuro I, Oka T, Hiroi Y, Mizuno T, et al. 1999. Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4. J. Biol. Chem. 274:8231-39
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8231-8239
-
-
Shiojima, I.1
Komuro, I.2
Oka, T.3
Hiroi, Y.4
Mizuno, T.5
-
109
-
-
0030465318
-
Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation
-
Chen JN, Fishman MC. 1996. Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122:3809-16
-
(1996)
Development
, vol.122
, pp. 3809-3816
-
-
Chen, J.N.1
Fishman, M.C.2
-
110
-
-
0033553573
-
Characterization of the murine A1 adenosine receptor promoter, potent regulation by GATA-4 and Nkx2.5
-
Rivkees SA, Chen M, Kulkarni J, Browne J, Zhao Z. 1999. Characterization of the murine A1 adenosine receptor promoter, potent regulation by GATA-4 and Nkx2.5. J. Biol. Chem. 274:14204-9
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14204-14209
-
-
Rivkees, S.A.1
Chen, M.2
Kulkarni, J.3
Browne, J.4
Zhao, Z.5
-
111
-
-
0034104297
-
Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis
-
Ruiz-Perez VL, Ide SE, Strom TM, Lorenz B, Wilson D, et al. 2000. Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis. Nat. Genet. 24:283-86
-
(2000)
Nat. Genet.
, vol.24
, pp. 283-286
-
-
Ruiz-Perez, V.L.1
Ide, S.E.2
Strom, T.M.3
Lorenz, B.4
Wilson, D.5
-
112
-
-
0043026950
-
High incidence of cardiac malformations in connexin40-deficient mice
-
Gu H, Smith FC, Taffet SM, Delmar M. 2003. High incidence of cardiac malformations in connexin40-deficient mice. Circ. Res. 93:201-6
-
(2003)
Circ. Res.
, vol.93
, pp. 201-206
-
-
Gu, H.1
Smith, F.C.2
Taffet, S.M.3
Delmar, M.4
-
113
-
-
0036660872
-
Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor
-
Muller JG, Thompson JT, Edmonson AM, Rackley MS, Kasahara H, et al. 2002. Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor. J. Mol. Cell. Cardiol. 34:807-21
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, pp. 807-821
-
-
Muller, J.G.1
Thompson, J.T.2
Edmonson, A.M.3
Rackley, M.S.4
Kasahara, H.5
-
114
-
-
0027500843
-
The two zinc finger-like domains of GATA-1 have different DNA binding specificities
-
Whyatt DJ, de Oer E, Grosveld F. 1993. The two zinc finger-like domains of GATA-1 have different DNA binding specificities. EMBO J. 12:4993-5005
-
(1993)
EMBO J.
, vol.12
, pp. 4993-5005
-
-
Whyatt, D.J.1
De Oer, E.2
Grosveld, F.3
-
115
-
-
0026648699
-
Distinct roles for the two cGATA-1 finger domains
-
Yang HY, Evans T. 1992. Distinct roles for the two cGATA-1 finger domains. Mol. Cell. Biol. 12:4562-70
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 4562-4570
-
-
Yang, H.Y.1
Evans, T.2
-
116
-
-
0030934971
-
GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily
-
Morrisey EE, Ip HS, Tang Z, Parmacek MS. 1997. GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily. J. Biol. Chem. 272:8515-24
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8515-8524
-
-
Morrisey, E.E.1
Ip, H.S.2
Tang, Z.3
Parmacek, M.S.4
-
117
-
-
0033070327
-
GATA transcription factors and cardiac development
-
Charron F, Nemer M. 1999. GATA transcription factors and cardiac development. Semin. Cell Dev. Biol. 10:85-91
-
(1999)
Semin. Cell Dev. Biol.
, vol.10
, pp. 85-91
-
-
Charron, F.1
Nemer, M.2
-
119
-
-
0035445835
-
Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome
-
Ghosh TK, Packham EA, Bonser AJ, Robinson TE, Cross SJ, Brook JD. 2001. Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum. Mol. Genet. 10:1983-94
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1983-1994
-
-
Ghosh, T.K.1
Packham, E.A.2
Bonser, A.J.3
Robinson, T.E.4
Cross, S.J.5
Brook, J.D.6
-
120
-
-
2442648749
-
TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed
-
Mori AD, Bruneau BG. 2004. TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed. Curr. Opin. Cardiol. 19:211-15
-
(2004)
Curr. Opin. Cardiol.
, vol.19
, pp. 211-215
-
-
Mori, A.D.1
Bruneau, B.G.2
-
121
-
-
0037424497
-
Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome
-
Fan C, Liu M, Wang Q. 2003. Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome. J. Biol. Chem. 278:8780-85
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8780-8785
-
-
Fan, C.1
Liu, M.2
Wang, Q.3
-
122
-
-
0035910569
-
Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins
-
Mizugishi K, Aruga J, Nakata K, Mikoshiba K. 2001. Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. J. Biol. Chem. 276:2180-88
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2180-2188
-
-
Mizugishi, K.1
Aruga, J.2
Nakata, K.3
Mikoshiba, K.4
-
123
-
-
0035831529
-
Physical and functional interactions between Zic and Gli proteins
-
Koyabu Y, Nakata K, Mizugishi K, Aruga J, Mikoshiba K. 2001. Physical and functional interactions between Zic and Gli proteins. J. Biol. Chem. 276:6889-92
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6889-6892
-
-
Koyabu, Y.1
Nakata, K.2
Mizugishi, K.3
Aruga, J.4
Mikoshiba, K.5
-
124
-
-
0034703026
-
Characterization of the activation domains of AP-2 family transcription factors
-
Wankhade S, Yu Y, Weinberg J, Tainsky MA, Kannan P. 2000. Characterization of the activation domains of AP-2 family transcription factors. J. Biol. Chem. 275:29701-8
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29701-29708
-
-
Wankhade, S.1
Yu, Y.2
Weinberg, J.3
Tainsky, M.A.4
Kannan, P.5
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