FOG-2, a heart- and brain-enriched cofactor for GATA transcription factors

Molecular and Cellular Biology

Volumn 19, Issue 6, 1999, Pages 4495-4502

  Lu, Jian Rong ^a   McKinsey, Timothy A ^a   Xu, Hongtao ^a   Wang, Da Zhi ^a   Richardson, James A ^b   Olson, Eric N ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN FOG 2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; EMBRYO; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; HEART MUSCLE CELL; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; RAT; TESTIS;

EID: 0033049126     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.6.4495     Document Type: Article

References (40)

1. Argentin, S., A. Ardati, S. Trembley, I. Lihrmann, L. Robitaille, J. Drouin, and M. Nemer. 1994. Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells. Mol. Cell. Biol. 14:777-790.
2. Clarke, M. F., J. F. Kukowska-Latallo, E. Westin, M. Smith, and E. V. Prochownik. 1988. Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol. Cell. Biol. 8:884-892.
3. Cubadda, Y., P. Heitzler, R. P. Ray, M. Bourouis, P. Ramain, W. Gelbart, P. Simpson, and M. Haenlin. 1997. u-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila. Genes Dev. 11:3083-3095.
4. Durocher, D., C.-Y. Chen, A. Ardati, R. J. Schwartz, and M. Nemer. 1996. The atrial natriuretic factor promoter is a downstream target for Nkx2.5 in the myocardium. Mol. Cell. Biol. 16:4648-4655.
5. Evans, T. 1997. Regulation of cardiac gene expression by GATA4/5/6. Trends Cardiovasc. Med. 7:75-83.
6. Evans, T., and G. Felsenfeld. 1998. The erythroid-specific transcription factor eryfl: a new finger protein. Cell 58:877-885.
7. Gove, C., M. Walmsley, S. Nijjar, D. Bertwistle, M. Guille, G. Partington, A. Bomford, and R. Patient. 1997. Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors. EMBO J. 16:355-368.
8. Grepin, C., L. L. Dagnino, L. Robitaille, L. L. Haberstroh, T. Antakely, and M. Nemer. 1994. A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription. Mol. Cell. Biol. 14:3115-3129.
9. Grepin, C., L. Robitaille, T. Antakely, and M. Nemer. 1995. Inhibition of transcription factor GATA-4 expression blocks in vitro cardiac muscle differentiation. Mol. Cell. Biol. 15:4095-4102.
10. Haenlin, M., Y. Cubadda, P. Blondeau, P. Heitzler, P. Lutz, P. Simpson, and P. Ramain. 1997. Transcriptional activity of Pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila. Genes Dev. 11:3096-3108.
11. Ip, H. S., D. B. Wilson, M. Heikinheimo, Z. Tang, C. N. Ting, M. C. Simon, J. M. Leiden, and M. S. Parmacek. 1994. The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Mol. Cell. Biol. 14:7517-7526.
12. Jiang, Y., and T. Evans. 1996. The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Dev. Biol. 174:257-270.
13. Kulessa, H., J. Frampton, and T. Graf. 1995. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes Dev. 9:1250-1262.
14. Kuo, C. T., E. E. Morrisey, R. Anandappa, K. Sigrist, M. M. Lu, M. S. Parmacek, C. Soudais, and J. M. Leiden. 1998. The GATA-4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 11:1048-1060.
15. Lachman, H. M., and A. I. Skoultchi. 1984. Expression of c-myc changes during differentiation of mouse erythroleukemia cells. Nature 310:592-594.
16. Laverriere, A. C., C. MacNeill, C. Mueller, R. E. Poelmann, J. B. Burch, and T. Evans. 1998. GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. J. Biol. Chem. 269:23177-23184.
17. Lawson, M. A., D. B. Whyte, and P. L. Mellon. 1996. GATA factors are essential for activity of the neuron-specific enhancer of the gonadotropin-releasing hormone gene. Mol. Cell. Biol. 16:3596-3605.
18. Lee, Y., T. Shioi, H. Kasahara, S. M. Jobe, R. J. Wiese, B. E. Markham, and S. Izumo. 1998. The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol. Cell. Biol. 18:3120-3129.
19. Lien, C.-L., C. Wu, B. Mercer, R. Webb, J. A. Richardson, and E. N. Olson. 1999. Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development 126:25-84.
20. Lu, J.-R., J. A. Richardson, and E. N. Olson. 1998. Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs. Mech. Dev. 73:23-32.
21. Molkentin, J. D., J. Lu, C. L. Antos, B. Markham, J. Richardson, J. Robbins, S. Grant, and E. N. Olson. 1998. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93:215-228.
22. Molkentin, J. D., D. Kalvakalanou, and B. E. Markham. 1994. Transcription factor GATA-4 regulates cardiac muscle-specific expression of the α-cardiac myosin heavy-chain gene in vivo. Mol. Cell. Biol. 14:4947-4957.
23. Molkentin, J. D., Q. Lin, S. A. Duncan, and E. N. Olson. 1997. Requirement of the transcription factor GATA-4 for heart tube formation and ventral morphogenesis. Genes Dev. 11:1061-1072.
24. Orkin, S. H. 1995. Hematopoiesis: how does it happen? Curr. Opin. Cell Biol. 7:870-877.
25. Pandolfi, P. P., M. E. Roth, A. Karis, M. W. Leonard, E. Dzierzak, F. G. Grosveld, and J. D. Engel. 1995. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis. Nat, Genet. 11:40-44.
26. Pevny, L., M. C. Simon, E. Robertson, W. H. Klein, S. F. Tsai, V. D'Agati, S. H. Orkin, and F. Constantini. 1991. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 349:257-260.
27. Pevny, L., C. S. Lin, V. D'Agati, M. C. Simon, S. H. Orkin, and F. Constantini. 1995. Development of hematopoietic cells lacking transcription factor GATA-1. Development 121:163-172.
28. Ramain, P., P. Heitzler, M. Haenlin, and P. Simpson. 1993. Pannier, a negative regulator of achaete and scute in Drosophila, encodes, a zinc finger protein with homology to the vertebrate transcription factor GATA-1. Development 119:1277-1291.
29. Robbins, J. 1997. Altering cardiac function via transgenesis. Trends Cardiovasc. Med. 7:185-191.
30. Searcy, R. D., E. B. Vincent, C. M. Liberatore, and K. E. Yutzey. 1998. A GATA-dependent Nkx2-5 regulatory element activates early cardiac gene expression in transgenic mice. Development 125:4461-4470.
31. Shivdasani, R. A., Y. Fujiwara, M. A. McDevitt, and S. H. Orkin. 1997. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 16: 3965-3973.
32. Thuerauf, D. J., D. S. Hanford, and C. C. Glembotski. 1994. Regulation of rat brain natriuretic peptide transcription. J. Biol. Chem. 269:17772-17775.
33. Ting, C. N., M. C. Olson, K. P. Barton, and J. M. Leiden. 1996. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature 384:474-478.
34. Tsai, S. F., D. J. Martin, L. I. Zon, A. D. D'Andrea, G. G. Wong, and S. H. Orkin. 1989. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature 33-446-451.
35. Tsai, S. F., G. Keller, C. T. Kuo, M. Weiss, J. Chen, M. Rosenblatt, F. W. Alt, and S. H. Orkin. 1994. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371:221-226.
36. Tsang, A. P., J. E. Visvader, C. A. Turner, Y. Fujiwara, C. Yu, M. Weiss, M. Crossley, and S. H. Orkin. 1997. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90:109-119.
37. Tsang, A. P., Y. Fujiwara, D. B. Hom, and S. H. Orkin. 1998. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes Dev. 12:1176-1188.
38. Visvader, J. E., M. Crossley, J. Hill, S. H. Orkin, and J. M. Adams. 1995. The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line. Mol. Cell. Biol. 15:634-641.
39. Weiss, M., C. Yu, and S. H. Orkin. 1997. Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. Mol. Cell. Biol. 17:1642-1651.
40. Yamamato, M., L. J. Ko, M. W. Leonard, H. Beug, S. H. Orkin, and J. D. Engel. 1990. Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Genes Dev. 4:1650-1662.