GATA4 is a dosage-sensitive regulator of cardiac morphogenesis

Developmental Biology

Volumn 275, Issue 1, 2004, Pages 235-244

  Pu, William T ^a,b   Ishiwata, Takahiro ^c   Juraszek, Amy L ^a,b   Ma, Qing ^c   Izumo, Seigo ^c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Cardiac morphogenesis; GATA4; Heart

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYCLIN D2; TRANSCRIPTION FACTOR GATA 4;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; ATRIOVENTRICULAR CANAL; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY BLOOD VESSEL; DIASTOLE; DIASTOLIC BLOOD PRESSURE; EMBRYO; GENE EXPRESSION; GENE TARGETING; GESTATION PERIOD; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART RIGHT VENTRICLE DOUBLE OUTLET; HEMODYNAMICS; HYPOPLASIA; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTOLE;

EID: 4644358238     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2004.08.008     Document Type: Article

References (31)

1. C.T. Basson, D.R. Bachinsky, R.C. Lin, T. Levi, J.A. Elkins, J. Soults, D. Grayzel, E. Kroumpouzou, T.A. Traill, J. Leblanc-Straceski, B. Renault, R. Kucherlapati, J.G. Seidman, and C.E. Seidman Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome Nat. Genet. 15 1997 30 35
2. C. Biben, R. Weber, S. Kesteven, E. Stanley, L. McDonald, D.A. Elliott, L. Barnett, F. Koentgen, L. Robb, M. Feneley, and R.P. Harvey Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5 Circ. Res. 87 2000 888 895
3. B.G. Bruneau, G. Nemer, J.P. Schmitt, F. Charron, L. Robitaille, S. Caron, D.A. Conner, M. Gessler, M. Nemer, C.E. Seidman, and J.G. Seidman A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease Cell 106 2001 709 721
4. F. Chen, H. Kook, R. Milewski, A.D. Gitler, M.M. Lu, J. Li, R. Nazarian, R. Schnepp, K. Jen, C. Biben, G. Runke, J.P. Mackay, J. Novotny, R.J. Schwartz, R.P. Harvey, M.C. Mullins, and J.A. Epstein Hop is an unusual homeobox gene that modulates cardiac development Cell 110 2002 713 723
5. J.D. Crispino, M.B. Lodish, B.L. Thurberg, S.H. Litovsky, T. Collins, J.D. Molkentin, and S.H. Orkin Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors Genes Dev. 15 2001 839 844
6. V. Garg, I.S. Kathiriya, R. Barnes, M.K. Schluterman, I.N. King, C.A. Butler, C.R. Rothrock, R.S. Eapen, K. Hirayama-Yamada, K. Joo, R. Matsuoka, J.C. Cohen, and D. Srivastava GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5 Nature 424 2003 443 447
7. J.I. Hoffman Incidence of congenital heart disease: I. Postnatal incidence Pediatr. Cardiol. 16 1995 103 113
8. T. Ishiwata, M. Nakazawa, W.T. Pu, S.G. Tevosian, and S. Izumo Developmental changes in ventricular diastolic function correlate with changes in ventricular myoarchitecture in normal mouse embryos Circ. Res. 93 2003 857 865
9. K. Kitta, R.M. Day, Y. Kim, I. Torregroza, T. Evans, and Y.J. Suzuki Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cells J. Biol. Chem. 278 2003 4705 4712
10. I. Kostetskii, Y. Jiang, E. Kostetskaia, S. Yuan, T. Evans, and M. Zile Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation Dev. Biol. 206 1999 206 218
11. C.T. Kuo, E.E. Morrisey, R. Anandappa, K. Sigrist, M.M. Lu, M.S. Parmacek, C. Soudais, and J.M. Leiden GATA4 transcription factor is required for ventral morphogenesis and heart tube formation Genes Dev. 11 1997 1048 1060
12. C.L. Lien, C. Wu, B. Mercer, R. Webb, J.A. Richardson, and E.N. Olson Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer Development 126 1999 75 84
13. J.D. Molkentin The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression J. Biol. Chem. 275 2000 38949 38952
14. J.D. Molkentin, Q. Lin, S.A. Duncan, and E.N. Olson Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis Genes Dev. 11 1997 1061 1072
15. N. Narita, M. Bielinska, and D.B. Wilson Wild-type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouse Dev. Biol. 189 1997 270 274
16. A.W. Nugent, P.E. Daubeney, P. Chondros, J.B. Carlin, M. Cheung, L.C. Wilkinson, A.M. Davis, S.G. Kahler, C.W. Chow, J.L. Wilkinson, and R.G. Weintraub The epidemiology of childhood cardiomyopathy in Australia N. Engl. J. Med. 348 2003 1639 1646
17. T. Pehlivan, B.R. Pober, M. Brueckner, S. Garrett, R. Slaugh, R. Van Rheeden, D.B. Wilson, M.S. Watson, and A.V. Hing GATA4 haploinsufficiency in patients with interstitial deletion of chromosome region 8p23.1 and congenital heart disease Am. J. Med. Genet. 83 1999 201 206
18. G.A. Porter Jr., R.F. Makuck, and S.A. Rivkees Intracellular calcium plays an essential role in cardiac development Dev. Dyn. 227 2003 280 290
19. C.I. Rodriguez, F. Buchholz, J. Galloway, R. Sequerra, J. Kasper, R. Ayala, A.F. Stewart, and S.M. Dymecki High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP Nat. Genet. 25 2000 139 140
20. J.J. Schott, D.W. Benson, C.T. Basson, W. Pease, G.M. Silberbach, J.P. Moak, B.J. Maron, C.E. Seidman, and J.G. Seidman Congenital heart disease caused by mutations in the transcription factor NKX2-5 Science 281 1998 108 111
21. R.D. Searcy, E.B. Vincent, C.M. Liberatore, and K.E. Yutzey A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice Development 125 1998 4461 4470
22. C.H. Shin, Z.P. Liu, R. Passier, C.L. Zhang, D.Z. Wang, T.M. Harris, H. Yamagishi, J.A. Richardson, G. Childs, and E.N. Olson Modulation of cardiac growth and development by HOP, an unusual homeodomain protein Cell 110 2002 725 735
23. D. Srivastava, and E.N. Olson A genetic blueprint for cardiac development Nature 407 2000 221 226
24. Y.J. Suzuki, R.M. Day, C.C. Tan, T.H. Sandven, Q. Liang, J.D. Molkentin, and B.L. Fanburg Activation of GATA-4 by serotonin in pulmonary artery smooth muscle cells J. Biol. Chem. 278 2003 17525 17531
25. M. Tanaka, Z. Chen, S. Bartunkova, N. Yamasaki, and S. Izumo The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development Development 126 1999 1269 1280
26. H. Tanaka, I. Matsumura, K. Nakajima, H. Daino, J. Sonoyama, H. Yoshida, K. Oritani, T. Machii, M. Yamamoto, T. Hirano, and Y. Kanakura GATA-1 blocks IL-6-induced macrophage differentiation and apoptosis through the sustained expression of cyclin D1 and bcl-2 in a murine myeloid cell line M1 Blood 95 2000 1264 1273
27. S.G. Tevosian, A.E. Deconinck, M. Tanaka, M. Schinke, S.H. Litovsky, S. Izumo, Y. Fujiwara, and S.H. Orkin FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium Cell 101 2000 729 739
28. J.T. Thompson, M.S. Rackley, and T.X. O'Brien Up-regulation of the cardiac homeobox gene Nkx2-5 (CSX) in feline right ventricular pressure overload Am. J. Physiol. 274 1998 H1569 H1573
29. Z. Wang, P. Sicinski, R.A. Weinberg, Y. Zhang, and K. Ravid Characterization of the mouse cyclin D3 gene: exon/intron organization and promoter activity Genomics 35 1996 156 163
30. L. Williams-Simons, and H. Westphal EIIaCreâ€"Utility of a general deleter strain Transgenic Res. 8 1999 53 54
31. R. Zeller, K.D. Bloch, B.S. Williams, R.J. Arceci, and C.E. Seidman Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis Genes Dev. 1 1987 693 698