GATA transcription factors and cardiac development

Seminars in Cell and Developmental Biology

Volumn 10, Issue 1, 1999, Pages 85-91

  Charron, Frédéric ^a,b   Nemer, Mona ^a,b,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Embryonic development; GATA factors; Heart; Transcription; Ventricular hypertrophy

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DNA BINDING PROTEIN; GATA 5A PROTEIN, XENOPUS; GATA 5B PROTEIN, XENOPUS; GATA-5A PROTEIN, XENOPUS; GATA-5B PROTEIN, XENOPUS; GATA4 PROTEIN, XENOPUS; GATA5 PROTEIN, HUMAN; GATA5 PROTEIN, MOUSE; GATA5 PROTEIN, RAT; GATA6 PROTEIN, HUMAN; GATA6 PROTEIN, MOUSE; GATA6 PROTEIN, XENOPUS; HOMEODOMAIN PROTEIN; NKX 2.5 PROTEIN, XENOPUS; NKX-2.5 PROTEIN, XENOPUS; NKX2 5 PROTEIN, HUMAN; NKX2 5 PROTEIN, MOUSE; NKX2-5 PROTEIN, HUMAN; NKX2-5 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 5; TRANSCRIPTION FACTOR GATA 6; XENOPUS PROTEIN;

ANIMAL; CARDIOMEGALY; CHICKEN; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART; HEART MUSCLE; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; PRENATAL DEVELOPMENT; RAT; REVIEW; SIGNAL TRANSDUCTION; XENOPUS;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CARDIOMEGALY; CHICKENS; DNA-BINDING PROTEINS; GATA4 TRANSCRIPTION FACTOR; GATA5 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HOMEODOMAIN PROTEINS; HUMANS; MICE; MYOCARDIUM; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; XENOPUS; XENOPUS PROTEINS;

EID: 0033070327     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1006/scdb.1998.0281     Document Type: Article

References (50)

1. Orkin SH (1995) Transcription factors and hematopoietic development. J Biol Chem 270:4955-4958
2. Simon MC (1995) Gotta have GATA. Nature Genet 11:9-11
3. Briegel K, Limi KC, Plank C, Beug H, Engel JD, Zenke M (1993) Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. Genes Dev 7:1097-1109
4. Ting CN, Olson MC, Barton KP, Leiden JM (1996) Transcription factor GATA-3 is required for development of the T-cell lineage. Nature 384:474-478
5. Pandolfi PP, Roth ME, Karis A, Leonard MW, Dzierzak E, Grosveld FG, Engel JD, Lindenbaum MH (1995) Targeted disruption of the GATA-3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis. Nature Genet 11:40-44
6. Pevny L, Simon MC, Robertson E, Klein WH, Tsai SF, D'Agati V, Orkin SH, Costantini F (1991) Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 349:257-260
7. Tsai FY, Keller G, Kuo FC, Weiss M, Chen J, Rosenblatt M, Alt FW, Orkin SH (1994) An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371:221-226
8. Grépin C, Dagnino L, Robitaille L, Haberstroh L, Antakly T, Nemer M (1994) A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription. Mol Cell Biol 14:3115-3129
9. Viger RS, Mertineit C, Trasler JM, Nemer M (1998) Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter. Development 125:2665-2675
10. Laverriere AC, MacNeill C, Mueller C, Poelmann RE, Burch JB, Evans T (1994) GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. J Biol Chem 269:23177-23184
11. Jiang YM, Evans T (1996) The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Dev Biol 174:258-270
12. Heikinheimo M, Scandrett JM, Wilson DB (1994) Localisation of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development. Dev Biol 164:361-373
13. Morrisey EE, Ip HS, Tang ZH, Lu MM, Parmacek MS (1997) GATA-5 - a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development. Dev Biol 183:21-36
14. Qureshi ST, Bronchain O, Nemer M, Malo D (1996) Mapping of the Gata6 gene to mouse chromosome 18. Mam Gen 7:705-706
15. Morrisey EE, Ip HS, Lu MM, Parmacek MS (1996) GATA-6 - a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm. Dev Biol 177:309-322
16. Gove C, Walmsley M, Nijjar S, Bertwistle D, Guille M, Partington G, Bomford A, Patient R (1997) Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors. EMBO J 16:355-368
17. Kelley C, Blumberg H, Zon LI, Evans T (1993) GATA-4 is a novel transcription factor expressed in endocardium of the developing heart. Development 118:817-827
18. Durocher D, Charron F, Warren R, Schwartz RJ, Nemer M (1997) The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J. 16:5687-5696
19. Ip HS, Wilson DB, Heikinheimo M, Tang Z, Ting CN, Simon MC, Leiden JM, Parmacek MS (1994) The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Mol Cell Biol 14:7517-7526
20. Murphy AM, Thompson WR, Peng LF, Jones L2 (1997) Regulation of the rat cardiac troponin I gene by the transcription factor GATA-4. Biochem J 322:393-401
21. Di Lisi R, Millino C, Calabria E, Altruda F, Schiaffino S, Ausoni S (1998) Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo. J Biol Chem 273:25371-25380
22. Rosoff ML, Nathanson NM (1998) GATA factor-dependent regulation of cardiac m2 muscarinic acetylcholine gene transcription. J Biol Chem 273:9124-9129
23. Wang GF, Nikovits WJR, Schleinitz M, Stockdale FE (1998) A positive GATA element and a negative vitamin D receptor-like element control atrial chamber-specific expression of a slow myosin heavy-chain gene during cardiac morphogenesis. Mol Cell Biol 18:6023-6034
24. Morrisey EE, Ip HS, Tang Z, Parmacek MS (1997) GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily. J Biol Chem 272:8515-8524
25. Grépin C, Robitaille L, Antakly T, Nemer M (1995) Inhibition of transcription factor GATA-4 expression blocks in vitro cardiac muscle differentiation. Mol Cell Biol 15:4095-4102
26. Grépin C, Nemer G, Nemer M (1997) Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor. Development 124:2387-2395
27. Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, Parmacek MS, Soudais C, Leiden JM (1997) GATA-4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev 11:1048-1060
28. Molkentin JD, Lin Q, Duncan SA, Olson EN (1997) Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev 11:1061-1072
29. Narita N, Bielinska M, Wilson DB (1997) Cardiomyocyte differentiation by GATA-4-deficient embryonic stem cells. Development 124:3755-3764
30. Serbedzija GN, Chen JN, Fishman MC (1998) Regulation in the heart field of zebrafish. Development 125:1095-1101
31. Harvey RP (1996) NK-2 homeobox genes and heart development. Dev Biol 178:203-216
32. Azpiazu N, Frasch M (1993) Tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev 7:1325-1340
33. Bodmer R (1993) The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118:719-729
34. Lyons I, Parsons LM, Hartley L, Li R, Andrews JE, Robb L, Harvey RP (1995) Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev 9:1654-1666
35. Chen JN, Fishman MC (1996) Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122:3809-3816
36. Cleaver OB, Patterson KD, Krieg PA (1996) Overexpression of the tinman-related genes XNKX-2.5 and XNKX-2.3 in xenopus embryos results in myocardial hyperplasia. Development 122:3549-3556
37. Durocher D, Chen CY, Ardati A, Schwartz RJ, Nemer M (1996) The ANF promoter is a downstream target for Nkx-2.5 in the myocardium. Mol Cell Biol 16:4648-4655
38. Sepulveda JL, Belaguli N, Nigam V, Chen CY, Nemer M, Schwartz RJ (1998) GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol Cell Biol 18:3405-3415
39. Lee Y, Shioi T, Kasahara H, Jobe SM, Wiese RJ, Markham BE, Izumo S (1998) The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol Cell Biol 18:3120-3129
40. Staehling-Hampton K, Hoffmann FM, Baylies MK, Rushton E, Bate M (1994) dpp induces mesodermal gene expression in Drosophila. Nature 372:783-786
41. Frasch M (1995) Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosaphila embryo. Nature 374:464-467
42. Hogan BL (1996) Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10:1580-1594
43. Schultheiss TM, Burch JB, Lassar AB (1997) A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev 11:451-62:26
44. Molkentin JD, Kalvakolanu DV, Markham BE (1994) Transcription factor GATA-4 regulates cardiac muscle-specific expression of the α-myosin heavy-chain gene. Mol Cell Biol 14:4947-4957
45. McGrew MJ, Bogdanova N, Hasegawa K, Hughes SH, Kitsis RN, Rosenthal N (1996) Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus. Mol Cell Biol 16:4524-4538
46. Herzig TC, Jobe SM, Aoki H, Molkentin JD, Cowley AW Jr, Izumo S, Markham BE (1997) Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc Natl Acad Sci USA 94:7543-7548
47. Hasegawa K, Lee SJ, Jobe SM, Markham BE, Kitsis RN (1997) cis-Acting sequences that mediate induction of beta-myosin heavy chain gene expression during left ventricular hypertrophy due to aortic constriction. Circulation 96:3943-3953
48. Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN (1998) A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93:215-228
49. Charron F, Paradis P, Bronchain O, Nemer G, Nemer M (1998) Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression. Submitted
50. Marttila M, Toth M, Nemer M, Ruskoaho H (1998) Transcriptional regulation of the BNP gene in response to hemodynamic stress through GATA-4 binding sites. Submitted