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Volumn 64, Issue 9, 2004, Pages 3022-3029

Apoptotic Signaling Pathways Induced by Nitric Oxide in Human Lymphoblastoid Cells Expressing Wild-Type or Mutant p53

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; DEATH RECEPTOR 5; ENDONUCLEASE; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; OXIDOREDUCTASE; PHOSPHATASE; PROCASPASE 10; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN MDM2; PROTEIN P53; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SURVIVIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

EID: 2342583373     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-1880     Document Type: Article
Times cited : (66)

References (52)
  • 3
    • 0036498865 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian cell death machinery
    • Joza N, Kroemer G, Penninger JM. Genetic analysis of the mammalian cell death machinery. Trends Genet 2002;18:142-9.
    • (2002) Trends Genet , vol.18 , pp. 142-149
    • Joza, N.1    Kroemer, G.2    Penninger, J.M.3
  • 4
    • 0031743648 scopus 로고    scopus 로고
    • p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
    • Muller M, Wilder S, Bannasch D, et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 1998;188:2033-45.
    • (1998) J Exp Med , vol.188 , pp. 2033-2045
    • Muller, M.1    Wilder, S.2    Bannasch, D.3
  • 6
    • 0035085998 scopus 로고    scopus 로고
    • p53 signaling and cell cycle checkpoints
    • Stewart ZA, Pietenpol JA. p53 signaling and cell cycle checkpoints. Chem Res Toxicol 2001;14:243-63.
    • (2001) Chem Res Toxicol , vol.14 , pp. 243-263
    • Stewart, Z.A.1    Pietenpol, J.A.2
  • 7
    • 0037037822 scopus 로고    scopus 로고
    • The p53 network in lung carcinogenesis
    • Robles AI, Linke SP, Harris CC. The p53 network in lung carcinogenesis. Oncogene 2002;21:6898-907.
    • (2002) Oncogene , vol.21 , pp. 6898-6907
    • Robles, A.I.1    Linke, S.P.2    Harris, C.C.3
  • 9
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995;80:293-9.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 10
    • 0031253977 scopus 로고    scopus 로고
    • KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
    • Wu GS, Bums TF, McDonald ER 3rd, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997;17:141-3.
    • (1997) Nat Genet , vol.17 , pp. 141-143
    • Wu, G.S.1    Bums, T.F.2    McDonald III, E.R.3
  • 12
    • 0032522463 scopus 로고    scopus 로고
    • p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
    • Sheikh MS, Burns TF, Huang Y, et al. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res 1998;58:1593-8.
    • (1998) Cancer Res , vol.58 , pp. 1593-1598
    • Sheikh, M.S.1    Burns, T.F.2    Huang, Y.3
  • 13
    • 0029003501 scopus 로고
    • Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
    • Owen-Schaub LB, Zhang W, Cusack JC, et al. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 1995;15:3032-40.
    • (1995) Mol Cell Biol , vol.15 , pp. 3032-3040
    • Owen-Schaub, L.B.1    Zhang, W.2    Cusack, J.C.3
  • 14
    • 0030871457 scopus 로고    scopus 로고
    • p53-dependent DNA damage-induced apoptosis requites Fas/ APO-1-independent activation of CPP32β
    • Fuchs EJ, McKenna KA, Bedi A. p53-dependent DNA damage-induced apoptosis requites Fas/APO-1-independent activation of CPP32β. Cancer Res 1997;57:2550-4.
    • (1997) Cancer Res , vol.57 , pp. 2550-2554
    • Fuchs, E.J.1    McKenna, K.A.2    Bedi, A.3
  • 15
    • 0035008833 scopus 로고    scopus 로고
    • Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene
    • Guan B, Yue P, Clayman GL, Sun SY. Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene. J Cell Physiol 2001;188:98-105.
    • (2001) J Cell Physiol , vol.188 , pp. 98-105
    • Guan, B.1    Yue, P.2    Clayman, G.L.3    Sun, S.Y.4
  • 16
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapototic gene, is induced by p53
    • Nakano K, Vousden KH. PUMA, a novel proapototic gene, is induced by p53. Mol Cell 2001;7:683-94.
    • (2001) Mol Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 18
    • 0034640281 scopus 로고    scopus 로고
    • Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
    • Oda E, Ohki R, Murasawa H, et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science (Wash DC) 2000;288:1053-8.
    • (2000) Science (Wash DC) , vol.288 , pp. 1053-1058
    • Oda, E.1    Ohki, R.2    Murasawa, H.3
  • 19
    • 0034977277 scopus 로고    scopus 로고
    • Apaf-1 is a transcriptional target for E2F and p53
    • Moroni MC, Hickman ES, Denchi EL, et al. Apaf-1 is a transcriptional target for E2F and p53. Nat Cell Biol 2001;3:552-8.
    • (2001) Nat Cell Biol , vol.3 , pp. 552-558
    • Moroni, M.C.1    Hickman, E.S.2    Denchi, E.L.3
  • 20
    • 0035884191 scopus 로고    scopus 로고
    • Apaf-1 is a transcriptional target of p53 in DNA damage-induced apoptosis
    • Robles AI, Bemmels NA, Foraker AB, Harris CC. Apaf-1 is a transcriptional target of p53 in DNA damage-induced apoptosis. Cancer Res 2001;61:6660-4.
    • (2001) Cancer Res , vol.61 , pp. 6660-6664
    • Robles, A.I.1    Bemmels, N.A.2    Foraker, A.B.3    Harris, C.C.4
  • 21
    • 0037314409 scopus 로고    scopus 로고
    • CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals
    • Jin S, Kalkum M, Overholtzer M, Stoffel A, Chait BT, Levine AJ. CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals. Genes Dev 2003;17:359-67.
    • (2003) Genes Dev , vol.17 , pp. 359-367
    • Jin, S.1    Kalkum, M.2    Overholtzer, M.3    Stoffel, A.4    Chait, B.T.5    Levine, A.J.6
  • 22
    • 0037427412 scopus 로고    scopus 로고
    • Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
    • Scorrano L, Korsmeyer SJ. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem Biophys Res Commun 2003;304:437-44.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 437-444
    • Scorrano, L.1    Korsmeyer, S.J.2
  • 23
    • 0035970721 scopus 로고    scopus 로고
    • Nuclear and mitochondrial apoptotic pathways of p53
    • Moll UM, Zaika A. Nuclear and mitochondrial apoptotic pathways of p53. FEBS Lett 2001;493:65-9.
    • (2001) FEBS Lett , vol.493 , pp. 65-69
    • Moll, U.M.1    Zaika, A.2
  • 24
    • 0036679174 scopus 로고    scopus 로고
    • Nitric oxide-induced genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells expressing wild-type and mutant p53
    • Li CQ, Trudel LJ, Wogan GN. Nitric oxide-induced genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells expressing wild-type and mutant p53. Proc Natl Acad Sci USA 2002;99:10364-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10364-10369
    • Li, C.Q.1    Trudel, L.J.2    Wogan, G.N.3
  • 25
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102:33-42.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 26
    • 0033521741 scopus 로고    scopus 로고
    • Molecular characterization of mitochondrial apoptosis-inducing factor
    • Susin SA, Lorenzo HK, Zamzami N, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature (Lond) 1999;397:441-6.
    • (1999) Nature (Lond) , vol.397 , pp. 441-446
    • Susin, S.A.1    Lorenzo, H.K.2    Zamzami, N.3
  • 27
    • 0035811496 scopus 로고    scopus 로고
    • Endonuclease G is an apoptotic DNase when released from mitochondria
    • Li LY, Luo X, Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature (Lond) 2001;412:95-9.
    • (2001) Nature (Lond) , vol.412 , pp. 95-99
    • Li, L.Y.1    Luo, X.2    Wang, X.3
  • 28
    • 0037159784 scopus 로고    scopus 로고
    • Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans
    • Wang X, Yang C, Chai J, Shi Y, Xue D. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science (Wash DC) 2002;298:1587-92.
    • (2002) Science (Wash DC) , vol.298 , pp. 1587-1592
    • Wang, X.1    Yang, C.2    Chai, J.3    Shi, Y.4    Xue, D.5
  • 29
    • 0034905394 scopus 로고    scopus 로고
    • XIAP: Apoptotic brake and promising therapeutic target
    • Holcik M, Gibson H, Korneluk RG. XIAP: apoptotic brake and promising therapeutic target. Apoptosis 2001;6:253-61.
    • (2001) Apoptosis , vol.6 , pp. 253-261
    • Holcik, M.1    Gibson, H.2    Korneluk, R.G.3
  • 30
    • 0034607655 scopus 로고    scopus 로고
    • Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
    • Yang Y, Fang S, Jensen JP, Weissman AM, Ashwell JD. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science (Wash DC) 2000;288:874-7.
    • (2000) Science (Wash DC) , vol.288 , pp. 874-877
    • Yang, Y.1    Fang, S.2    Jensen, J.P.3    Weissman, A.M.4    Ashwell, J.D.5
  • 31
    • 0036479115 scopus 로고    scopus 로고
    • Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
    • Hoffman WH, Biade S, Zilfou JT, Chen J, Murphy M. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 2002;277:3247-57.
    • (2002) J Biol Chem , vol.277 , pp. 3247-3257
    • Hoffman, W.H.1    Biade, S.2    Zilfou, J.T.3    Chen, J.4    Murphy, M.5
  • 32
    • 18344369169 scopus 로고    scopus 로고
    • Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway
    • Mirza A, McGuirk M, Hockenberry TN, et al. Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway. Oncogene 2002;21:2613-22.
    • (2002) Oncogene , vol.21 , pp. 2613-2622
    • Mirza, A.1    McGuirk, M.2    Hockenberry, T.N.3
  • 33
    • 0036231450 scopus 로고    scopus 로고
    • Genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells exposed to peroxynitrite generated from SIN-1
    • Li CQ, Trudel LJ, Wogan GN. Genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells exposed to peroxynitrite generated from SIN-1. Chem Res Toxicol 2002;15:527-35.
    • (2002) Chem Res Toxicol , vol.15 , pp. 527-535
    • Li, C.Q.1    Trudel, L.J.2    Wogan, G.N.3
  • 34
    • 0032190057 scopus 로고    scopus 로고
    • p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines
    • Yu Y, Little JB. p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines. Cancer Res 1998;58:4277-81.
    • (1998) Cancer Res , vol.58 , pp. 4277-4281
    • Yu, Y.1    Little, J.B.2
  • 37
    • 0037422535 scopus 로고    scopus 로고
    • Nitric oxide-induced cellular stress and p53 activation in chronic inflammation
    • Hofseth LJ, Saito S, Hussain SP, et al. Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc Natl Acad Sci USA 2003;100:143-8.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 143-148
    • Hofseth, L.J.1    Saito, S.2    Hussain, S.P.3
  • 38
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death and cancer
    • Oren M. Decision making by p53: life, death and cancer. Cell Death Differ 2003; 10:431-42.
    • (2003) Cell Death Differ , vol.10 , pp. 431-442
    • Oren, M.1
  • 39
    • 0037013199 scopus 로고    scopus 로고
    • p53 activation by nitric oxide involves down-regulation of Mdm2
    • Wang X, Michael D, de Murcia G, Oren M. p53 activation by nitric oxide involves down-regulation of Mdm2. J Biol Chem 2002;277:15697-702.
    • (2002) J Biol Chem , vol.277 , pp. 15697-15702
    • Wang, X.1    Michael, D.2    De Murcia, G.3    Oren, M.4
  • 41
    • 0034383398 scopus 로고    scopus 로고
    • p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation
    • Takekawa M, Adachi M, Nakahata A, et al. p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. EMBO J 2000;19:6517-26.
    • (2000) EMBO J , vol.19 , pp. 6517-6526
    • Takekawa, M.1    Adachi, M.2    Nakahata, A.3
  • 42
    • 0034256962 scopus 로고    scopus 로고
    • p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest
    • Flatt PM, Polyak K, Tang LJ, et al. p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. Cancer Lett 2000;156:63-72.
    • (2000) Cancer Lett , vol.156 , pp. 63-72
    • Flatt, P.M.1    Polyak, K.2    Tang, L.J.3
  • 43
    • 0031828828 scopus 로고    scopus 로고
    • Reactive oxidants from nitric oxide, oxidants and cellular signalling, and repair of oxidative DNA damage: A Chemical Pathology Study Section workshop
    • Liebler DC, Aust AE, Wilson GL, Copeland ES. Reactive oxidants from nitric oxide, oxidants and cellular signalling, and repair of oxidative DNA damage: a Chemical Pathology Study Section workshop. Mol Carcinog 1998;22:209-20.
    • (1998) Mol Carcinog , vol.22 , pp. 209-220
    • Liebler, D.C.1    Aust, A.E.2    Wilson, G.L.3    Copeland, E.S.4
  • 44
    • 0034523818 scopus 로고    scopus 로고
    • Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
    • Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 2000;7:1166-73.
    • (2000) Cell Death Differ , vol.7 , pp. 1166-1173
    • Korsmeyer, S.J.1    Wei, M.C.2    Saito, M.3    Weiler, S.4    Oh, K.J.5    Schlesinger, P.H.6
  • 45
    • 0035023857 scopus 로고    scopus 로고
    • Regulation of inhibitor of apoptosis expression by nitric oxide and cytokines: Relation to apoptosis induction in rat mesangial cells and raw 264.7 macrophages
    • Manderscheid M, Messmer UK, Franzen R, Pfeilschifter J. Regulation of inhibitor of apoptosis expression by nitric oxide and cytokines: relation to apoptosis induction in rat mesangial cells and raw 264.7 macrophages. J Am Soc Nephrol 2001;12:1151-63.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1151-1163
    • Manderscheid, M.1    Messmer, U.K.2    Franzen, R.3    Pfeilschifter, J.4
  • 46
    • 20244376287 scopus 로고    scopus 로고
    • Increased survivin transcript levels: An independent negative predictor of survival in soft tissue sarcoma patients
    • Kappler M, Kohler T, Kampf C, et al. Increased survivin transcript levels: an independent negative predictor of survival in soft tissue sarcoma patients. Int J Cancer 2001;95:360-3.
    • (2001) Int J Cancer , vol.95 , pp. 360-363
    • Kappler, M.1    Kohler, T.2    Kampf, C.3
  • 47
    • 0034667372 scopus 로고    scopus 로고
    • Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells
    • Sasaki H, Sheng Y, Kotsuji F, Tsang BK. Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells. Cancer Res 2000;60:5659-66.
    • (2000) Cancer Res , vol.60 , pp. 5659-5666
    • Sasaki, H.1    Sheng, Y.2    Kotsuji, F.3    Tsang, B.K.4
  • 48
    • 0038722727 scopus 로고    scopus 로고
    • Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis
    • Yang QH, Church-Hajduk R, Ren J, Newton ML, Du C. Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis. Genes Dev 2003;17:1487-96.
    • (2003) Genes Dev , vol.17 , pp. 1487-1496
    • Yang, Q.H.1    Church-Hajduk, R.2    Ren, J.3    Newton, M.L.4    Du, C.5
  • 49
    • 0034117177 scopus 로고    scopus 로고
    • Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
    • Daugas E, Susin SA, Zamzami N, et al. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J 2000;14:729-39.
    • (2000) FASEB J , vol.14 , pp. 729-739
    • Daugas, E.1    Susin, S.A.2    Zamzami, N.3
  • 50
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science (Wash DC) 2001;292:727-30.
    • (2001) Science (Wash DC) , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3
  • 51
    • 0037192790 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein
    • Sun XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM. Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. J Biol Chem 2002;277:11345-51.
    • (2002) J Biol Chem , vol.277 , pp. 11345-11351
    • Sun, X.M.1    Bratton, S.B.2    Butterworth, M.3    MacFarlane, M.4    Cohen, G.M.5
  • 52
    • 0034671945 scopus 로고    scopus 로고
    • Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
    • Sigal A, Rotter V. Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res 2000;60:6788-93.
    • (2000) Cancer Res , vol.60 , pp. 6788-6793
    • Sigal, A.1    Rotter, V.2


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