System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-β peptide 1- 40

Journal of Neuroscience

Volumn 26, Issue 12, 2006, Pages 3345-3356

  Qin, Si ^a,b   Colin, Catherine ^a,b   Hinners, Ina ^a,b,d   Gervais, Annie ^a,b   Cheret, Cyril ^a,b   Mallat, Michel ^a,b,c  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d KeyNeurotek AG   (Germany)

Author keywords

Alzheimer's disease; Apolipoprotein E; Microglia; Neuronal death; NMDA receptor; System X c

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; ANTIPORTER; APOLIPOPROTEIN E; CYSTEINE; GLUTAMIC ACID; ISOPROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; AMINO ACID TRANSPORTER; AMYLOID BETA PROTEIN; PEPTIDE FRAGMENT; SLC7A11 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE INACTIVATION; GENE TARGETING; HUMAN; MALE; MICROGLIA; MOUSE; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; RAT; SENILE PLAQUE; TRANSGENIC MOUSE; WILD TYPE; ALZHEIMER DISEASE; ANIMAL; C57BL MOUSE; CELL COMMUNICATION; CELL DEATH; CELL SURVIVAL; COCULTURE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; NERVE DEGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION; WISTAR RAT;

ALZHEIMER DISEASE; AMINO ACID TRANSPORT SYSTEM Y+; AMYLOID BETA-PROTEIN; ANIMALS; APOLIPOPROTEINS E; CELL COMMUNICATION; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; FEMALE; GENE EXPRESSION REGULATION; GLUTAMIC ACID; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROGLIA; NERVE DEGENERATION; NEURONS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR;

EID: 33645217828     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5186-05.2006     Document Type: Article

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