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Volumn 85, Issue 4, 2003, Pages 925-934

Amyloid precursor protein-processing products affect mononuclear phagocyte activation: Pathways for sAPP- and Aβ-mediated neurotoxicity

Author keywords

Alzheimer's disease; Amyloid precursor protein; Glutamate; Microglia; Neurotoxicity

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CYTOKINE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SUPEROXIDE DISMUTASE;

EID: 0037573524     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01739.x     Document Type: Article
Times cited : (39)

References (38)
  • 1
    • 0030610645 scopus 로고    scopus 로고
    • Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E
    • Barger S. and Harmon A. (1997) Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388, 878-881.
    • (1997) Nature , vol.388 , pp. 878-881
    • Barger, S.1    Harmon, A.2
  • 2
    • 0035146889 scopus 로고    scopus 로고
    • Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
    • Barger S. W. and Basile A. S. (2001) Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. J. Neurochem. 76, 846-854.
    • (2001) J. Neurochem. , vol.76 , pp. 846-854
    • Barger, S.W.1    Basile, A.S.2
  • 4
    • 0032983334 scopus 로고    scopus 로고
    • Beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease
    • Bianca V. D., Dusi S., Bianchini E., Dal Pra I. and Rossi F. (1999) beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease. J. Biol. Chem. 274, 15493-15499.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15493-15499
    • Bianca, V.D.1    Dusi, S.2    Bianchini, E.3    Dal Pra, I.4    Rossi, F.5
  • 5
    • 0345381021 scopus 로고    scopus 로고
    • Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage
    • Chapman G. A., Moores K., Harrison D., Campbell C. A., Stewart B. R. and Strijbos P. J. (2000) Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage. J. Neurosci. 20, RC87.
    • (2000) J. Neurosci. , vol.20
    • Chapman, G.A.1    Moores, K.2    Harrison, D.3    Campbell, C.A.4    Stewart, B.R.5    Strijbos, P.J.6
  • 7
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T. and Holbrook N. J. (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408, 239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 10
    • 0028105846 scopus 로고
    • Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture
    • Giulian D., Li J., Leara B. and Keenen C. (1994) Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture. Neurochem. Int. 25, 227-233.
    • (1994) Neurochem. Int. , vol.25 , pp. 227-233
    • Giulian, D.1    Li, J.2    Leara, B.3    Keenen, C.4
  • 11
    • 0029040685 scopus 로고
    • Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain
    • Giulian D., Haverkamp L., Li J. and Karshin W. (1995) Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain. Neurochem. Int. 27, 119-137.
    • (1995) Neurochem. Int. , vol.27 , pp. 119-137
    • Giulian, D.1    Haverkamp, L.2    Li, J.3    Karshin, W.4
  • 12
    • 0002125233 scopus 로고    scopus 로고
    • Rat hippocampal neurons in low-density culture
    • Goslin K. and Banker G., eds. The MIT Press, Cambridge, MA
    • Goslin K., Asmussen H. and Banker G. (1998) Rat hippocampal neurons in low-density culture, in Culturing Nerve Cells, 2 Edition (Goslin K. and Banker G., eds), pp. 339-370. The MIT Press, Cambridge, MA.
    • (1998) Culturing Nerve Cells, 2 Edition , pp. 339-370
    • Goslin, K.1    Asmussen, H.2    Banker, G.3
  • 15
    • 0032562615 scopus 로고    scopus 로고
    • Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein
    • Ikezu T., Trapp B. D., Song K. S., Schlegel A., Lisanti M. P. and Okamoto T. (1998) Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein. J. Biol. Chem. 273, 10485-10495.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10485-10495
    • Ikezu, T.1    Trapp, B.D.2    Song, K.S.3    Schlegel, A.4    Lisanti, M.P.5    Okamoto, T.6
  • 18
    • 0037207291 scopus 로고    scopus 로고
    • Transduction of bovine adrenal chromaffin cells using a recombinant adenovirus expressing GFP
    • Li X., Drakulich D., Zhang P., Shen M., Weber G. A., Ikezu T. and Hexum T. (2002) Transduction of bovine adrenal chromaffin cells using a recombinant adenovirus expressing GFP. J. Neurosci. Methods 122, 91-96.
    • (2002) J. Neurosci. Methods , vol.122 , pp. 91-96
    • Li, X.1    Drakulich, D.2    Zhang, P.3    Shen, M.4    Weber, G.A.5    Ikezu, T.6    Hexum, T.7
  • 19
  • 20
    • 0037308834 scopus 로고    scopus 로고
    • C1q-calreticulin induced oxidative neurotoxicity: Relevance for the neuropathogenesis of Alzheimer's disease
    • Luo X., Weber G. A., Zheng J., Gendelman H. E. and Ikezu T. (2003) C1q-calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease. J. Neuroimmunol. 135, 62-71.
    • (2003) J. Neuroimmunol. , vol.135 , pp. 62-71
    • Luo, X.1    Weber, G.A.2    Zheng, J.3    Gendelman, H.E.4    Ikezu, T.5
  • 21
    • 0032944604 scopus 로고    scopus 로고
    • Inflammation of the brain in Alzheimer's disease: Implications for therapy
    • McGeer P. L. and McGeer E. G. (1999) Inflammation of the brain in Alzheimer's disease: implications for therapy. J. Leukoc. Biol. 65, 409-415.
    • (1999) J. Leukoc. Biol. , vol.65 , pp. 409-415
    • McGeer, P.L.1    McGeer, E.G.2
  • 22
    • 0032891880 scopus 로고    scopus 로고
    • Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35]
    • Meda L., Baron P., Prat E., Scarpini E., Scarlato G., Cassatella M. A. and Rossi F. (1999) Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35]. J. Neuroimmunol. 93, 45-52.
    • (1999) J. Neuroimmunol. , vol.93 , pp. 45-52
    • Meda, L.1    Baron, P.2    Prat, E.3    Scarpini, E.4    Scarlato, G.5    Cassatella, M.A.6    Rossi, F.7
  • 25
    • 0026907151 scopus 로고
    • A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid
    • Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B. and Lannfelt L. (1992) A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nat. Genet. 1, 345-347.
    • (1992) Nat. Genet. , vol.1 , pp. 345-347
    • Mullan, M.1    Crawford, F.2    Axelman, K.3    Houlden, H.4    Lilius, L.5    Winblad, B.6    Lannfelt, L.7
  • 26
    • 0024678458 scopus 로고
    • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • Murphy T. H., Miyamoto M., Sastre A., Schnaar R. L. and Coyle J. T. (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2, 1547-1558.
    • (1989) Neuron , vol.2 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 27
    • 0033006151 scopus 로고    scopus 로고
    • Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide
    • Noda M., Nakanishi H. and Akaike N. (1999) Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide. Neuroscience 92, 1465-1474.
    • (1999) Neuroscience , vol.92 , pp. 1465-1474
    • Noda, M.1    Nakanishi, H.2    Akaike, N.3
  • 28
    • 0026743059 scopus 로고
    • Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines
    • Piani D., Spranger M., Frei K., Schaffner A. and Fontana A. (1992) Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines. Eur. J. Immunol. 22, 2429-2436.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2429-2436
    • Piani, D.1    Spranger, M.2    Frei, K.3    Schaffner, A.4    Fontana, A.5
  • 29
    • 0035478598 scopus 로고    scopus 로고
    • Oxidative glutamate toxicity can be a component of the excitotoxicity cascade
    • Schubert D. and Piasecki D. (2001) Oxidative glutamate toxicity can be a component of the excitotoxicity cascade. J. Neurosci. 21, 7455-7462.
    • (2001) J. Neurosci. , vol.21 , pp. 7455-7462
    • Schubert, D.1    Piasecki, D.2
  • 30
    • 0028118846 scopus 로고
    • Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death
    • Shearman M. S., Ragan C. I. and Iversen L. L. (1994) Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death. Proc. Natl Acad. Sci. USA 91, 1470-1474.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 1470-1474
    • Shearman, M.S.1    Ragan, C.I.2    Iversen, L.L.3
  • 32
    • 0026726052 scopus 로고
    • Electrophysiological recording from Xenopus oocytes
    • Stuhmer W. (1992) Electrophysiological recording from Xenopus oocytes. Meth Enzymol 207, 319-339.
    • (1992) Meth Enzymol. , vol.207 , pp. 319-339
    • Stuhmer, W.1
  • 34
    • 0032984124 scopus 로고    scopus 로고
    • A predominant apoptotic death pathway of neuronal PC12 cells induced by activated microglia is displaced by a non-apoptotic death pathway following blockage of caspase-3-dependent cascade
    • Tanabe K., Nakanishi H., Maeda H., Nishioku T, Hashimoto K., Liou S. Y., Akamine A. and Yamamoto K. (1999) A predominant apoptotic death pathway of neuronal PC12 cells induced by activated microglia is displaced by a non-apoptotic death pathway following blockage of caspase-3-dependent cascade. J. Biol. Chem. 274, 15725-15731.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15725-15731
    • Tanabe, K.1    Nakanishi, H.2    Maeda, H.3    Nishioku, T.4    Hashimoto, K.5    Liou, S.Y.6    Akamine, A.7    Yamamoto, K.8
  • 35
    • 0028484557 scopus 로고
    • Downregulation of in vitro neurotoxicity of brain macrophages by prostaglandin E2 and a beta-adrenergic agonist
    • Thery C., Dobbertin A. and Mallat M. (1994) Downregulation of in vitro neurotoxicity of brain macrophages by prostaglandin E2 and a beta-adrenergic agonist. Glia 11, 383-386.
    • (1994) Glia , vol.11 , pp. 383-386
    • Thery, C.1    Dobbertin, A.2    Mallat, M.3
  • 36
    • 0033118464 scopus 로고    scopus 로고
    • The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages
    • Van Muiswinkel F. L., Raupp S. F., de Vos N. M., Smits H. A., Verhoef J., Eikelenboom P. and Nottet H. S. (1999) The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages. J. Neuroimmunol. 96, 121-130.
    • (1999) J. Neuroimmunol. , vol.96 , pp. 121-130
    • Van Muiswinkel, F.L.1    Raupp, S.F.2    De Vos, N.M.3    Smits, H.A.4    Verhoef, J.5    Eikelenboom, P.6    Nottet, H.S.7
  • 38
    • 0032983786 scopus 로고    scopus 로고
    • Memantine in severe dementia: Results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine)
    • Winblad B. and Poritis N. (1999) Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine). Int. J. Geriatr. Psychiatry 14, 135-146.
    • (1999) Int. J. Geriatr. Psychiatry , vol.14 , pp. 135-146
    • Winblad, B.1    Poritis, N.2


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