-
1
-
-
0023838532
-
1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
-
1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 52:487-501; 1988.
-
(1988)
Cell
, vol.52
, pp. 487-501
-
-
Abraham, C.R.1
Selkoe, D.J.2
Potter, H.3
-
3
-
-
0025265675
-
1-antichymotrypsin is associated solely with amyloid deposits containing the β-protein and is localized in specific cells of both normal and diseased brain
-
1-antichymotrypsin is associated solely with amyloid deposits containing the β-protein and is localized in specific cells of both normal and diseased brain. Neurobiol. Aging 11:123-129; 1990.
-
(1990)
Neurobiol. Aging
, vol.11
, pp. 123-129
-
-
Abraham, C.R.1
Shirahama, T.2
Potter, H.3
-
4
-
-
0028588694
-
Congo Red protects against toxicity of β-amyloid peptides on rat hippocampal neurones
-
4. Burgevin, M.-C.; Passat, M.; Daniel, N.; Capet, M.; Doble, A. Congo Red protects against toxicity of β-amyloid peptides on rat hippocampal neurones. Neuroreport 5:2429-2432; 1994.
-
(1994)
Neuroreport
, vol.5
, pp. 2429-2432
-
-
Burgevin, M.-C.1
Passat, M.2
Daniel, N.3
Capet, M.4
Doble, A.5
-
5
-
-
0026756887
-
Methodological variables in the assessment of beta amyloid neurotoxicity
-
5. Busciglio, J.; Lorenzo, A.; Yankner, B. A. Methodological variables in the assessment of beta amyloid neurotoxicity. Neurobiol. Aging 13: 609-612; 1992.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 609-612
-
-
Busciglio, J.1
Lorenzo, A.2
Yankner, B.A.3
-
6
-
-
0028178004
-
Brain interleukin-1β in Alzheimer's disease and vascular dementia
-
6. Cacabelos, R.; Alvarez, X. A.; Fernandez-Novoa, L.; Franco, A.; Mangues, R.; Pellicar, A.; Nishimura, T. Brain interleukin-1β in Alzheimer's disease and vascular dementia. Methods Find. Exp. Clin. Pharmacol. 16:141-151; 1994.
-
(1994)
Methods Find. Exp. Clin. Pharmacol.
, vol.16
, pp. 141-151
-
-
Cacabelos, R.1
Alvarez, X.A.2
Fernandez-Novoa, L.3
Franco, A.4
Mangues, R.5
Pellicar, A.6
Nishimura, T.7
-
7
-
-
0027526419
-
Release of excess amyloid β protein from a mutant β protein precursor
-
7. Cai, X.-D.; Golde, T. E.; Younkin, S. G. Release of excess amyloid β protein from a mutant β protein precursor. Science 259:514-5161 1993.
-
(1993)
Science
, vol.259
, pp. 514-5161
-
-
Cai, X.-D.1
Golde, T.E.2
Younkin, S.G.3
-
8
-
-
0022878817
-
In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease β-protein
-
8. Castaño, E. M.; Ghiso, J.; Prelli, F.; Gorevic, P. D.; Migheli, A.; Frangione, B. In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease β-protein. Biochem. Biophys. Res. Commun. 141:782-789; 1986.
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.141
, pp. 782-789
-
-
Castaño, E.M.1
Ghiso, J.2
Prelli, F.3
Gorevic, P.D.4
Migheli, A.5
Frangione, B.6
-
9
-
-
0026075602
-
Early onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
-
9. Chartier-Harlin M.-C.; Crawford, F.; Houlden, H.; Warren, A.; Hughes, D.; Fidandi, L.; et al. Early onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene. Nature 353:844-846; 1991.
-
(1991)
Nature
, vol.353
, pp. 844-846
-
-
Chartier-Harlin, M.-C.1
Crawford, F.2
Houlden, H.3
Warren, A.4
Hughes, D.5
Fidandi, L.6
-
10
-
-
0028178047
-
Apolipoprotein E, E4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region
-
10. Chartier-Harlin, M.-C.; Parfitt, M.; Legrain, S.; Perez-Tur, J.; et al. Apolipoprotein E, E4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region. Hum. Mol. Genet. 3:569-574; 1994.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 569-574
-
-
Chartier-Harlin, M.-C.1
Parfitt, M.2
Legrain, S.3
Perez-Tur, J.4
-
11
-
-
0026745610
-
Mutation of the β-amyloid precursor protein in familial Alzheimer's diseases increases β-protein production
-
11. Citron, M.; Oltersdorf, T.; Haass, C.; McConlogue, L.; Hung, A. Y.; Seubert, P.; et al. Mutation of the β-amyloid precursor protein in familial Alzheimer's diseases increases β-protein production. Nature 360:672-674; 1992.
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
-
12
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
12. Corder, E. H.; Saunders, A. M.; Strittmatter, W. J.; Schmechel, D. E.; et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923; 1993.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
-
13
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
-
13. Corder, E. H.; Saunders, A. M.; Risch, N. J.; Strittmatter, W. J.; et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat. Genet. 7:180-184; 1994.
-
(1994)
Nat. Genet.
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
Strittmatter, W.J.4
-
14
-
-
0028889206
-
Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1
-
14. Das, S.; Potter, H. Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron 14:447-456; 1995.
-
(1995)
Neuron
, vol.14
, pp. 447-456
-
-
Das, S.1
Potter, H.2
-
15
-
-
0029160765
-
A biotechnological method provides access to aggregation component monomeric Alzheimer's 1-42 residue amyloid peptide
-
15. Döbeli, H.; Draeger, N.; Huber, G.; Jakob, P.; et al. A biotechnological method provides access to aggregation component monomeric Alzheimer's 1-42 residue amyloid peptide. Biotechniques 13:988-993; 1995.
-
(1995)
Biotechniques
, vol.13
, pp. 988-993
-
-
Döbeli, H.1
Draeger, N.2
Huber, G.3
Jakob, P.4
-
16
-
-
0027258149
-
Cells with a familial Alzheimer's disease mutation produce authentic β-peptide
-
16. Dovey, H. F.; Suomensaari-Chrysler, S.; Lieberburg, I.; Sinha, S.; Keim, P. S. Cells with a familial Alzheimer's disease mutation produce authentic β-peptide. Neuroreport 4:1039-1042; 1993.
-
(1993)
Neuroreport
, vol.4
, pp. 1039-1042
-
-
Dovey, H.F.1
Suomensaari-Chrysler, S.2
Lieberburg, I.3
Sinha, S.4
Keim, P.S.5
-
18
-
-
0028872558
-
Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implications for the pathogenesis and treatment of Alzheimer's disease
-
18. Evans, K. C.; Berger, E. P.; Cho, C.-G.; Weisgraber, K. H.; Lansbury, P. T. Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implications for the pathogenesis and treatment of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 92:763-767; 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 763-767
-
-
Evans, K.C.1
Berger, E.P.2
Cho, C.-G.3
Weisgraber, K.H.4
Lansbury, P.T.5
-
20
-
-
0028981009
-
Solubilization of β amyloid-(1-42) peptide: Reversing the β-sheet conformation induced by aluminum with silicates
-
20. Fasman, G. D.; Perczel, A.; Moore, C. D. Solubilization of β amyloid-(1-42) peptide: Reversing the β-sheet conformation induced by aluminum with silicates. Proc. Natl. Acad. Sci. USA 92:369-371; 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 369-371
-
-
Fasman, G.D.1
Perczel, A.2
Moore, C.D.3
-
22
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
22. Glenner, G. G.; Wong, C. W. Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 122:885-890; 1984.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
23
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer disease
-
23. Goate, A.; Chartier-Harlin, M.-C.; Mullan, M.; Brown, J.; Crawford, F.; Fidani, L.; Giuffra, L.; et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer disease. Nature 349:704-706; 1991.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
-
24
-
-
0022449937
-
Abnormal in vivo metabolism of apolipoprotein E4 in humans
-
24. Gregg, R. E.; Zech, L. A.; Schaefer, E. J.; Stark, D.; Wilson, D.; Brewer, H. B. Abnormal in vivo metabolism of apolipoprotein E4 in humans. J. Clin. Invest. 78:815-821; 1986.
-
(1986)
J. Clin. Invest.
, vol.78
, pp. 815-821
-
-
Gregg, R.E.1
Zech, L.A.2
Schaefer, E.J.3
Stark, D.4
Wilson, D.5
Brewer, H.B.6
-
25
-
-
0001360461
-
Brain interleukin-1 and S100 immunoreactivity elevated in Down's syndrome and Alzheimer's disease
-
25. Griffin, W. S. T.; Stanley, L. C.; Ling, C.; et al. Brain interleukin-1 and S100 immunoreactivity elevated in Down's syndrome and Alzheimer's disease. Proc. Natl. Acad. Sci. USA 86:7611-7615; 1989.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7611-7615
-
-
Griffin, W.S.T.1
Stanley, L.C.2
Ling, C.3
-
26
-
-
0028926976
-
Interleukin-1 expression in different plaque types in Alzheimer's disease: Significance in plaque evolution
-
26. Griffin, W. S. T.; Sheng, J. G.; Roberts, G. W.; Mrak, R. E. Interleukin-1 expression in different plaque types in Alzheimer's disease: Significance in plaque evolution. J. Neuropathol. Exp. Neurol. 54: 276-281; 1995.
-
(1995)
J. Neuropathol. Exp. Neurol.
, vol.54
, pp. 276-281
-
-
Griffin, W.S.T.1
Sheng, J.G.2
Roberts, G.W.3
Mrak, R.E.4
-
27
-
-
0026879650
-
Presenile dementia and cerebral hemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene
-
27. Hendriks, L.; Van Duijn, C. M.; Cras, P.; et al. Presenile dementia and cerebral hemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene. Nat. Genet. 1:218-221; 1992.
-
(1992)
Nat. Genet.
, vol.1
, pp. 218-221
-
-
Hendriks, L.1
Van Duijn, C.M.2
Cras, P.3
-
28
-
-
0028987849
-
Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular site of catabolism
-
28. Higaki, J.; Quon, D.; Zhong, Z.; Cordell, B. Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular site of catabolism. Neuron 14:651-659; 1995.
-
(1995)
Neuron
, vol.14
, pp. 651-659
-
-
Higaki, J.1
Quon, D.2
Zhong, Z.3
Cordell, B.4
-
29
-
-
0028899724
-
Quantitative analysis of senile plaques in Alzheimer disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome)
-
29. Hyman, B. T.; West, H. L.; Rebeck, G. W.; Buldyrev, S. V.; Mantegna, R. N.; Ukleja, M.; Havlin, S.; Stanley, H. E. Quantitative analysis of senile plaques in Alzheimer disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome). Proc. Natl. Acad. Sci. USA 92:3586-3590; 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3586-3590
-
-
Hyman, B.T.1
West, H.L.2
Rebeck, G.W.3
Buldyrev, S.V.4
Mantegna, R.N.5
Ukleja, M.6
Havlin, S.7
Stanley, H.E.8
-
30
-
-
0028169925
-
Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)
-
30. Iwatsubo, T.; Odaka, A.; Suzuki, N.; Mizusawa, H.; Nukina, N.; Ihara, Y. Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43). Neuron 13:45-53; 1994.
-
(1994)
Neuron
, vol.13
, pp. 45-53
-
-
Iwatsubo, T.1
Odaka, A.2
Suzuki, N.3
Mizusawa, H.4
Nukina, N.5
Ihara, Y.6
-
31
-
-
0027195933
-
Seeding "one-dimensional crystalization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
-
31. Jarrett, J. T.; Lansbury, P. T. Seeding "one-dimensional crystalization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73:1055-1058; 1993.
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury, P.T.2
-
32
-
-
0027258525
-
The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
32. Jarrett, J. T.; Berger, E. P.; Lansbury, P. T. The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease. Biochemistry 32:4693-4697; 1993.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury, P.T.3
-
34
-
-
0023425365
-
Synthetic β-peptide of Alzheimer disease forms amyloid-like fibrils in vitro
-
34. Kirschner, D. A.; Inouye, H.; Duffy, L. K.; Sinclair, A.; Selkoe, D. J. Synthetic β-peptide of Alzheimer disease forms amyloid-like fibrils in vitro. Proc. Natl. Acad. Sci. USA 84:6953-6957; 1987.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 6953-6957
-
-
Kirschner, D.A.1
Inouye, H.2
Duffy, L.K.3
Sinclair, A.4
Selkoe, D.J.5
-
35
-
-
0028913416
-
Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: Implications for Alzheimer's disease
-
35. Kisilevsky, R.; Lemieux, L. J.; Fraser, P. E.; Kong, X.; Hultin, P. G.; Szarek, W. A. Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: Implications for Alzheimer's disease. Nat. Med. 1:143-148; 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 143-148
-
-
Kisilevsky, R.1
Lemieux, L.J.2
Fraser, P.E.3
Kong, X.4
Hultin, P.G.5
Szarek, W.A.6
-
37
-
-
0028286934
-
Lack of association between apolipoprotein E allele E4 and sporadic Alzheimer's disease
-
37. Lannfelt, L.; Lilius, L.; Nastase, M.; Viitanen, M.; et al. Lack of association between apolipoprotein E allele E4 and sporadic Alzheimer's disease. Neurosci. Lett. 169:175-178; 1994.
-
(1994)
Neurosci. Lett.
, vol.169
, pp. 175-178
-
-
Lannfelt, L.1
Lilius, L.2
Nastase, M.3
Viitanen, M.4
-
38
-
-
0025296269
-
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, dutch type
-
38. Levy, E.; Carman, M. D.; Fernandez-Madrid, I. J.; Power, M. D.; Lieberburg, I.; Van Duinen, S. G.; Bots, G. T. A. M.; Luyendijk, W.; Frangione, B. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, dutch type. Science 248:1124-1126; 1990.
-
(1990)
Science
, vol.248
, pp. 1124-1126
-
-
Levy, E.1
Carman, M.D.2
Fernandez-Madrid, I.J.3
Power, M.D.4
Lieberburg, I.5
Van Duinen, S.G.6
Bots, G.T.A.M.7
Luyendijk, W.8
Frangione, B.9
-
39
-
-
0029150716
-
A familial Alzheimer's disease locus on chromosome 1
-
39. Levy-Lahad, E.; Wijsman, E. M.; Nemens, E.; Anderson, L.; Goddard, K. A. B.; Weber, J. L.; Bird, T. D.; Schellenberg, G. D. A familial Alzheimer's disease locus on chromosome 1. Science 269:970-973; 1995.
-
(1995)
Science
, vol.269
, pp. 970-973
-
-
Levy-Lahad, E.1
Wijsman, E.M.2
Nemens, E.3
Anderson, L.4
Goddard, K.A.B.5
Weber, J.L.6
Bird, T.D.7
Schellenberg, G.D.8
-
40
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
40. Levy-Lahad, E.; Wasco, W.; Poorkaj, P.; Romano, D. M.; Oshima, J.; Pettingell, W. H.; Yu, C.-E.; Jondro, P. D.; Schmidt, S. D.; Wang, K.; Crowley, A. C.; Fu, Y.-H.; Guenette, S. Y.; Galas, D.; Nemens, E.; Wijsman, E. M.; Bird, T. D.; Schellenberg, G. D.; Tanzi, R. E. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269:973-977; 1995.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.-E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.-H.12
Guenette, S.Y.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
41
-
-
0029618686
-
A potential familial Alzheimer's disease gene on chromosome 1 related to AD3
-
41. Li, J.; Ma, J.; Potter, H. A potential familial Alzheimer's disease gene on chromosome 1 related to AD3. Proc. Natl. Acad. Sci. USA 92: 12180-12184; 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12180-12184
-
-
Li, J.1
Ma, J.2
Potter, H.3
-
42
-
-
0027717482
-
Characterization of amyloid fibril β-peptide in familial Alzheimer's disease with APP717 mutations
-
42. Liepnieks, J. J.; Ghetti, B.; Farlow, M.; Roses, A. D.; Benson, M. D. Characterization of amyloid fibril β-peptide in familial Alzheimer's disease with APP717 mutations. Biochem. Biophys. Res. Commun. 197:386-392; 1993.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.197
, pp. 386-392
-
-
Liepnieks, J.J.1
Ghetti, B.2
Farlow, M.3
Roses, A.D.4
Benson, M.D.5
-
43
-
-
0028172886
-
β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo Red
-
43. Lorenzo, A.; Yankner, B. A. β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo Red. Proc. Natl. Acad. Sci. USA 91:12243-12247; 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
44
-
-
0028173205
-
1antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
-
1antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 372:92-94; 1994.
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer, H.B.3
Das, S.4
Potter, H.5
-
45
-
-
0028816355
-
Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotype risks
-
45. Maestre, G.; Ottman, R.; Stern, Y.; Gurland, B.; et al. Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotype risks. Ann. Neurol. 37:254-259; 1995.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 254-259
-
-
Maestre, G.1
Ottman, R.2
Stern, Y.3
Gurland, B.4
-
46
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
46. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63; 1983.
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
47
-
-
0026907151
-
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
-
47. Mullan, M.; Crawford, F.; Axelman, K.; Houlden, H.; Lulius, L.; Winblad, B.; Lannfelt, L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid. Nat. Genet. 1:345-347; 1992.
-
(1992)
Nat. Genet.
, vol.1
, pp. 345-347
-
-
Mullan, M.1
Crawford, F.2
Axelman, K.3
Houlden, H.4
Lulius, L.5
Winblad, B.6
Lannfelt, L.7
-
48
-
-
0025971426
-
Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
-
48. Namba, Y.; Tomonaga, M.; Kawasaki, H.; Otomon, E.; Ikeda, K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. 541:163-166; 1991.
-
(1991)
Brain Res.
, vol.541
, pp. 163-166
-
-
Namba, Y.1
Tomonaga, M.2
Kawasaki, H.3
Otomon, E.4
Ikeda, K.5
-
49
-
-
0028106152
-
Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer disease and normal aging
-
49. Näslund, J.; Schierhorn, A.; Hellman, U.; Lannfelt, L.; Roses, A. D.; et al. Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer disease and normal aging. Proc. Natl. Acad. Sci. USA 91:8378-8382; 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8378-8382
-
-
Näslund, J.1
Schierhorn, A.2
Hellman, U.3
Lannfelt, L.4
Roses, A.D.5
-
50
-
-
0029043032
-
Apolipoprotein E polymorphism influences not only cerebral senile plaque load but also Alzheimer-type neurofibrillary tangle formation
-
50. Ohm, T. G.; Kirca, M.; Bohl, J.; Scharnagl, H.; Groß, W.; März, W. Apolipoprotein E polymorphism influences not only cerebral senile plaque load but also Alzheimer-type neurofibrillary tangle formation. Neuroscience 66:583-587; 1995.
-
(1995)
Neuroscience
, vol.66
, pp. 583-587
-
-
Ohm, T.G.1
Kirca, M.2
Bohl, J.3
Scharnagl, H.4
Groß, W.5
März, W.6
-
52
-
-
0025735884
-
Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage
-
52. Pericak-Vance, M. A.; Bebout, J. L.; Gaskell, P. C.; Yamaoka, L. H.; et al. Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage. Am. J. Hum. Genet. 48:1034-1050; 1991.
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 1034-1050
-
-
Pericak-Vance, M.A.1
Bebout, J.L.2
Gaskell, P.C.3
Yamaoka, L.H.4
-
54
-
-
0025992417
-
In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity
-
54. Pike, C. J.; Walencewicz, A. J.; Glabe, C. G.; Cotman, C. W. In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563:311-314; 1991.
-
(1991)
Brain Res.
, vol.563
, pp. 311-314
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
Cotman, C.W.4
-
55
-
-
0027447286
-
Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
-
55. Pike, C. J.; Burdick, D.; Walencewicz, A. J.; Glabe, C. G.; Cotman, C. W. Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state. J. Neurosci. 13:1676-1687; 1993.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
57
-
-
0002742452
-
1antichymotrypsin and β-protein form a stable complex in vitro
-
Iqbal, K.; MacLachlan, D. R. C.; Winblad, B.; Wisniewski, H. M., eds. New York: John Wiley & Sons
-
1antichymotrypsin and β-protein form a stable complex in vitro. In: Iqbal, K.; MacLachlan, D. R. C.; Winblad, B.; Wisniewski, H. M., eds. Alzheimer's disease: Basic mechanisms, diagnosis, and therapeutic strategies. New York: John Wiley & Sons; 1991:275-279.
-
(1991)
Alzheimer's Disease: Basic Mechanisms, Diagnosis, and Therapeutic Strategies
, pp. 275-279
-
-
Potter, H.1
Abraham, C.R.2
Dressier, D.3
-
58
-
-
0027082694
-
The involvement of proteases, protease inhibitors, and an acute phase response in Alzheimer's disease
-
58. Potter, H.; Nelson, R. B.; Das, S.; Siman, R.; Kayyali, U. S.; Dressler, D. The involvement of proteases, protease inhibitors, and an acute phase response in Alzheimer's disease. Ann. NY Acad. Sci. 674:161-173; 1992.
-
(1992)
Ann. NY Acad. Sci.
, vol.674
, pp. 161-173
-
-
Potter, H.1
Nelson, R.B.2
Das, S.3
Siman, R.4
Kayyali, U.S.5
Dressler, D.6
-
59
-
-
0001421726
-
Beyond β-protein: New steps in the pathogenic pathway to Alzheimer's disease
-
Iqbal, K.; Mortimer, J. A.; Winblad, B.; Wisniewski, W. H., eds. New York: John Wiley & Sons
-
59. Potter, H.; Ma, J.; Das, S.; Geller, L. N.; Benjamin, M.; Kayyali. U. S.; Dressler, D. Beyond β-protein: New steps in the pathogenic pathway to Alzheimer's disease. In: Iqbal, K.; Mortimer, J. A.; Winblad, B.; Wisniewski, W. H., eds. Research advances in Alzheimer's disease and related disorders. New York: John Wiley & Sons; 1995:643-654.
-
(1995)
Research Advances in Alzheimer's Disease and Related Disorders
, pp. 643-654
-
-
Potter, H.1
Ma, J.2
Das, S.3
Geller, L.N.4
Benjamin, M.5
Kayyali, U.S.6
Dressler, D.7
-
60
-
-
0027374047
-
Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
-
60. Rebeck, G. W.; Reiter, J. S.; Strickland, D. K.; Hyman, B. T. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions. Neuron 11:575-580; 1993.
-
(1993)
Neuron
, vol.11
, pp. 575-580
-
-
Rebeck, G.W.1
Reiter, J.S.2
Strickland, D.K.3
Hyman, B.T.4
-
61
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
61. Rogaev, E. I.; Sherrington, R.; Rogaeva, E. A.; Levesque, G.; Ikeda, M.; Liang, Y.; Chi, H.; Lin, C.; Holman, K.; Tsuda, T.; Mar, L.; Sorbl, S.; Nacmias, B.; Piacentini, S.; Amaducci, L.; Chumakov, I.; Cohen, D.; Lannfelt, L.; Fraser, P.E.; Rommens, J. M.; St. George-Hyslop, P. H. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376:775-778; 1995.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
Mar, L.11
Sorbl, S.12
Nacmias, B.13
Piacentini, S.14
Amaducci, L.15
Chumakov, I.16
Cohen, D.17
Lannfelt, L.18
Fraser, P.E.19
Rommens, J.M.20
St. George-Hyslop, P.H.21
more..
-
62
-
-
0027332081
-
β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer's disease
-
62. Roher, A. E.; Lowenson, J. D.; Clarke, S.; Woods, A. S.; Cotter, R. J.; Gowing, E.; Ball, M. J. β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 90:10836-10840; 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10836-10840
-
-
Roher, A.E.1
Lowenson, J.D.2
Clarke, S.3
Woods, A.S.4
Cotter, R.J.5
Gowing, E.6
Ball, M.J.7
-
63
-
-
0025002021
-
Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease
-
63. Rozemuller, J. M.; Stam, F. C.; Eikelenboom, P. Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease. Neurosci. Lett. 119:75-78; 1990.
-
(1990)
Neurosci. Lett.
, vol.119
, pp. 75-78
-
-
Rozemuller, J.M.1
Stam, F.C.2
Eikelenboom, P.3
-
65
-
-
0028026587
-
Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils
-
65. Sanan, D. A.; Weisgraber, K. H.; Russell, S. J.; Mahley, R. W.; Huang, D.; et al. Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils. J. Clin. Invest. 94:860-869; 1994.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 860-869
-
-
Sanan, D.A.1
Weisgraber, K.H.2
Russell, S.J.3
Mahley, R.W.4
Huang, D.5
-
66
-
-
0029073383
-
Genetic dissection of Alzheimer disease, a heterogeneous disorder
-
66. Schellenberg, G. D. Genetic dissection of Alzheimer disease, a heterogeneous disorder. Proc. Natl. Acad. Sci. USA 92:8552-8559; 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8552-8559
-
-
Schellenberg, G.D.1
-
67
-
-
0026471656
-
Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14
-
67. Schellenberg, G. D.; Bird, T. D.; Wijsman, E. M.; Orr, H. T.; Anderson, L.; Nemens, E.; White, J. A.; Bonnycastle, L.; Weber, J. L.; Alonsa, M. E.; Potter, H.; Heston, L. L.; Martin, G. M. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science 258:668-671; 1992.
-
(1992)
Science
, vol.258
, pp. 668-671
-
-
Schellenberg, G.D.1
Bird, T.D.2
Wijsman, E.M.3
Orr, H.T.4
Anderson, L.5
Nemens, E.6
White, J.A.7
Bonnycastle, L.8
Weber, J.L.9
Alonsa, M.E.10
Potter, H.11
Heston, L.L.12
Martin, G.M.13
-
68
-
-
0027365822
-
Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
-
68. Schmechel, D. E.; Saunders, A. M.; Strittmatter, W. J.; Grain, B. J.; et al. Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:9649-9653;1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
Grain, B.J.4
-
69
-
-
0027999030
-
Transthyretin sequesters amyloid β protein and prevents amyloid formation
-
69. Schwartzman, A. L.; Gregori, L.; Vitek, M. P.; Lyubski, S.; et al. Transthyretin sequesters amyloid β protein and prevents amyloid formation. Proc. Natl. Acad. Sci. USA 91:8368-8372; 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8368-8372
-
-
Schwartzman, A.L.1
Gregori, L.2
Vitek, M.P.3
Lyubski, S.4
-
70
-
-
0028170818
-
Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease
-
70. Selkoe, D. J. Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10:373-403; 1994.
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 373-403
-
-
Selkoe, D.J.1
-
71
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early onset familial Alzheimer's disease
-
71. Sherrington, R.; Rogaev, E. I.; Liang, Y.; Rogaeva, E. A.; Levesque, G.; et al. Cloning of a gene bearing missense mutations in early onset familial Alzheimer's disease. Nature 375:754-760; 1995.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
-
73
-
-
0001744084
-
Plasma amyloid β-protein (Aβ) ending at Aβ42(43) is increased in carriers of familial AD (FAD) linked to chromosome 14
-
73. Song, X.-H.; Suzuki, N.; Bird, T.; Peskind, E.; Schellenberg. G. D.; Younkin, S. G. Plasma amyloid β-protein (Aβ) ending at Aβ42(43) is increased in carriers of familial AD (FAD) linked to chromosome 14. Soc. Neurosci. Abstr. 21:1501; 1995.
-
(1995)
Soc. Neurosci. Abstr.
, vol.21
, pp. 1501
-
-
Song, X.-H.1
Suzuki, N.2
Bird, T.3
Peskind, E.4
Schellenberg, G.D.5
Younkin, S.G.6
-
74
-
-
0027032695
-
Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14
-
74. St. George-Hyslop, P.; Haines, J.; Rogaev, E.; Mortilla, M.; Vaula, G.; et al. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nat. Genet. 2:330-334; 1992.
-
(1992)
Nat. Genet.
, vol.2
, pp. 330-334
-
-
St. George-Hyslop, P.1
Haines, J.2
Rogaev, E.3
Mortilla, M.4
Vaula, G.5
-
75
-
-
0027407565
-
Apolipoprotein E: High affinity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
75. Strittmatter, W. J.; Saunders, A. M.; Schmechel, D.; Pericak-Vance, M.; Enghild, J.; Salvesen, G. S.; Roses, A. D. Apolipoprotein E: High affinity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:1977-1981; 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
76
-
-
0028322017
-
An increased percentage of long amyloid β-protein by familial amyloid β-protein precursor (βAPP717) mutants
-
76. Suzuki, N.; Cheung, T. T.; Cai, M.-D.; Odaka, A.; Otvos, L.; Eckman, C.; Golde, T. E.; Younkin, S. G. An increased percentage of long amyloid β-protein by familial amyloid β-protein precursor (βAPP717) mutants. Science 264:1336-1340; 1994.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, M.-D.3
Odaka, A.4
Otvos, L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
77
-
-
0028587336
-
APP717 missence mutation affects the ratio of amyloid β protein species (Aβ1-42/43 and Aβ1-40) in familial Alzheimer's disease brain
-
77. Tamaoka, A.; Odaka, A.; Ishibashi, Y.; Usami, M.; Sahara, N.; Suzuki, N.; Nukina, N.; Mizusawa, H.; Shoji, S.; Kanazawa, I.; Mori, H. APP717 missence mutation affects the ratio of amyloid β protein species (Aβ1-42/43 and Aβ1-40) in familial Alzheimer's disease brain. J. Biol. Chem. 269:32721-32724; 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32721-32724
-
-
Tamaoka, A.1
Odaka, A.2
Ishibashi, Y.3
Usami, M.4
Sahara, N.5
Suzuki, N.6
Nukina, N.7
Mizusawa, H.8
Shoji, S.9
Kanazawa, I.10
Mori, H.11
-
78
-
-
0028331604
-
Amyloid β protein-induced neuronal cell death: Neurotoxic properties of aggregated amyloid β protein
-
78. Ueda, K.; Fukui, Y.; Kageyama, H. Amyloid β protein-induced neuronal cell death: Neurotoxic properties of aggregated amyloid β protein. Brain Res. 639:240-244; 1994.
-
(1994)
Brain Res.
, vol.639
, pp. 240-244
-
-
Ueda, K.1
Fukui, Y.2
Kageyama, H.3
-
79
-
-
0025369198
-
Amyloid β protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)
-
79. Van Broeckhoven, C.; Hann, J.; Bakker, E.; Hardy, J. A.; Van Hul, W.; Wehnert, A.; Vegter-Van der Vlis, M.; et al. Amyloid β protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch). Science 248:1120-1122; 1990.
-
(1990)
Science
, vol.248
, pp. 1120-1122
-
-
Van Broeckhoven, C.1
Hann, J.2
Bakker, E.3
Hardy, J.A.4
Van Hul, W.5
Wehnert, A.6
Vegter-Van Der Vlis, M.7
-
80
-
-
0027031612
-
Mapping of a gene predisposing to early onset Alzheimer's disease to chromosome 14q24.3
-
80. Van Broeckhoven, C.; Backhovens, H.; Cruts, M.; De Winter, G.; Bruyland, M.; Cras, P.; Martin J.-J. Mapping of a gene predisposing to early onset Alzheimer's disease to chromosome 14q24.3. Nat. Genet. 2:335-339;1992.
-
(1992)
Nat. Genet.
, vol.2
, pp. 335-339
-
-
Van Broeckhoven, C.1
Backhovens, H.2
Cruts, M.3
De Winter, G.4
Bruyland, M.5
Cras, P.6
Martin, J.-J.7
-
81
-
-
0028350675
-
ApoE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease
-
81. Van Broeckhoven, C.; Backhovens, H.; Cruts, M.; Martin, J. J.; Crook, R.; Houlden, H.; Hardy, J. ApoE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease. Neurosci. Lett. 169:179-180; 1994.
-
(1994)
Neurosci. Lett.
, vol.169
, pp. 179-180
-
-
Van Broeckhoven, C.1
Backhovens, H.2
Cruts, M.3
Martin, J.J.4
Crook, R.5
Houlden, H.6
Hardy, J.7
-
82
-
-
0028988736
-
The apolipoprotein E ∈2 allele is associated with an increased risk of early onset Alzheimer's disease and a reduced survival
-
82. Van Duijn, C. M.; de Knijff, P.; Wehnert, A.; De Voecht, J.; et al. The apolipoprotein E ∈2 allele is associated with an increased risk of early onset Alzheimer's disease and a reduced survival. Ann. Neurol. 37: 605-610; 1995.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 605-610
-
-
Van Duijn, C.M.1
De Knijff, P.2
Wehnert, A.3
De Voecht, J.4
-
83
-
-
0026045862
-
Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation
-
83. Wisniewski, T.; Ghiso, J.; Frangione, B. Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochem. Biophys. Res. Commun. 179:1247-1254; 1991.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.179
, pp. 1247-1254
-
-
Wisniewski, T.1
Ghiso, J.2
Frangione, B.3
-
84
-
-
0026542786
-
Apolipoprotein E: A pathologic chaperone in patients with cerebral and systemic amyloid
-
84. Wisniewski, T.; Frangione, B. Apolipoprotein E: A pathologic chaperone in patients with cerebral and systemic amyloid. Neurosci. Lett. 135:235-238; 1992.
-
(1992)
Neurosci. Lett.
, vol.135
, pp. 235-238
-
-
Wisniewski, T.1
Frangione, B.2
-
85
-
-
0027255422
-
Apolipoprotein E: Binding to soluble Alzheimer's β-amyloid
-
85. Wisniewski, T.; Golabek, A.; Matsubara, E.; Ghiso, J.; Frangione, B. Apolipoprotein E: Binding to soluble Alzheimer's β-amyloid. Biochem. Biophys. Res. Commun. 192:359-365; 1993.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.192
, pp. 359-365
-
-
Wisniewski, T.1
Golabek, A.2
Matsubara, E.3
Ghiso, J.4
Frangione, B.5
-
86
-
-
0027970307
-
Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro
-
86. Wisniewski, T.; Castaño, E. M.; Golabek, A.; Vogel, T.; Frangione, B. Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am. J. Pathol. 145:1030-1035; 1994.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1030-1035
-
-
Wisniewski, T.1
Castaño, E.M.2
Golabek, A.3
Vogel, T.4
Frangione, B.5
-
87
-
-
0026432318
-
β-Amyloid and the pathogenesis of Alzheimer's disease
-
87. Yankner, B. A.; Mesulam, M.-M. β-Amyloid and the pathogenesis of Alzheimer's disease. N. Engl. J. Med. 325:1849; 1991.
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 1849
-
-
Yankner, B.A.1
Mesulam, M.-M.2
-
88
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid β-protein: Reversal by tachykinin neuro-peptides
-
88. Yankner, B. A.; Duffy, L. K.; Kirschner, D. A. Neurotrophic and neurotoxic effects of amyloid β-protein: Reversal by tachykinin neuro-peptides. Science 250:280-282; 1990.
-
(1990)
Science
, vol.250
, pp. 280-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
|