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Volumn 17, Issue 5, 1996, Pages 773-780

Alzheimer Aβ neurotoxicity: Promotion by antichymotrypsin, ApoE4; inhibition by Aβ-related peptides

Author keywords

ACT; Acute phase response; Alzheimer's disease; Amyloid; apoE; IL 1; Inflammation

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; INTERLEUKIN 1;

EID: 0000448998     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-4580(96)00112-1     Document Type: Article
Times cited : (100)

References (88)
  • 1
    • 0023838532 scopus 로고
    • 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
    • 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 52:487-501; 1988.
    • (1988) Cell , vol.52 , pp. 487-501
    • Abraham, C.R.1    Selkoe, D.J.2    Potter, H.3
  • 3
    • 0025265675 scopus 로고
    • 1-antichymotrypsin is associated solely with amyloid deposits containing the β-protein and is localized in specific cells of both normal and diseased brain
    • 1-antichymotrypsin is associated solely with amyloid deposits containing the β-protein and is localized in specific cells of both normal and diseased brain. Neurobiol. Aging 11:123-129; 1990.
    • (1990) Neurobiol. Aging , vol.11 , pp. 123-129
    • Abraham, C.R.1    Shirahama, T.2    Potter, H.3
  • 4
    • 0028588694 scopus 로고
    • Congo Red protects against toxicity of β-amyloid peptides on rat hippocampal neurones
    • 4. Burgevin, M.-C.; Passat, M.; Daniel, N.; Capet, M.; Doble, A. Congo Red protects against toxicity of β-amyloid peptides on rat hippocampal neurones. Neuroreport 5:2429-2432; 1994.
    • (1994) Neuroreport , vol.5 , pp. 2429-2432
    • Burgevin, M.-C.1    Passat, M.2    Daniel, N.3    Capet, M.4    Doble, A.5
  • 5
    • 0026756887 scopus 로고
    • Methodological variables in the assessment of beta amyloid neurotoxicity
    • 5. Busciglio, J.; Lorenzo, A.; Yankner, B. A. Methodological variables in the assessment of beta amyloid neurotoxicity. Neurobiol. Aging 13: 609-612; 1992.
    • (1992) Neurobiol. Aging , vol.13 , pp. 609-612
    • Busciglio, J.1    Lorenzo, A.2    Yankner, B.A.3
  • 7
    • 0027526419 scopus 로고
    • Release of excess amyloid β protein from a mutant β protein precursor
    • 7. Cai, X.-D.; Golde, T. E.; Younkin, S. G. Release of excess amyloid β protein from a mutant β protein precursor. Science 259:514-5161 1993.
    • (1993) Science , vol.259 , pp. 514-5161
    • Cai, X.-D.1    Golde, T.E.2    Younkin, S.G.3
  • 8
    • 0022878817 scopus 로고
    • In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease β-protein
    • 8. Castaño, E. M.; Ghiso, J.; Prelli, F.; Gorevic, P. D.; Migheli, A.; Frangione, B. In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease β-protein. Biochem. Biophys. Res. Commun. 141:782-789; 1986.
    • (1986) Biochem. Biophys. Res. Commun. , vol.141 , pp. 782-789
    • Castaño, E.M.1    Ghiso, J.2    Prelli, F.3    Gorevic, P.D.4    Migheli, A.5    Frangione, B.6
  • 9
    • 0026075602 scopus 로고
    • Early onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
    • 9. Chartier-Harlin M.-C.; Crawford, F.; Houlden, H.; Warren, A.; Hughes, D.; Fidandi, L.; et al. Early onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene. Nature 353:844-846; 1991.
    • (1991) Nature , vol.353 , pp. 844-846
    • Chartier-Harlin, M.-C.1    Crawford, F.2    Houlden, H.3    Warren, A.4    Hughes, D.5    Fidandi, L.6
  • 10
    • 0028178047 scopus 로고
    • Apolipoprotein E, E4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region
    • 10. Chartier-Harlin, M.-C.; Parfitt, M.; Legrain, S.; Perez-Tur, J.; et al. Apolipoprotein E, E4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region. Hum. Mol. Genet. 3:569-574; 1994.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 569-574
    • Chartier-Harlin, M.-C.1    Parfitt, M.2    Legrain, S.3    Perez-Tur, J.4
  • 11
    • 0026745610 scopus 로고
    • Mutation of the β-amyloid precursor protein in familial Alzheimer's diseases increases β-protein production
    • 11. Citron, M.; Oltersdorf, T.; Haass, C.; McConlogue, L.; Hung, A. Y.; Seubert, P.; et al. Mutation of the β-amyloid precursor protein in familial Alzheimer's diseases increases β-protein production. Nature 360:672-674; 1992.
    • (1992) Nature , vol.360 , pp. 672-674
    • Citron, M.1    Oltersdorf, T.2    Haass, C.3    McConlogue, L.4    Hung, A.Y.5    Seubert, P.6
  • 12
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • 12. Corder, E. H.; Saunders, A. M.; Strittmatter, W. J.; Schmechel, D. E.; et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923; 1993.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3    Schmechel, D.E.4
  • 13
    • 0028305380 scopus 로고
    • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
    • 13. Corder, E. H.; Saunders, A. M.; Risch, N. J.; Strittmatter, W. J.; et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat. Genet. 7:180-184; 1994.
    • (1994) Nat. Genet. , vol.7 , pp. 180-184
    • Corder, E.H.1    Saunders, A.M.2    Risch, N.J.3    Strittmatter, W.J.4
  • 14
    • 0028889206 scopus 로고
    • Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1
    • 14. Das, S.; Potter, H. Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron 14:447-456; 1995.
    • (1995) Neuron , vol.14 , pp. 447-456
    • Das, S.1    Potter, H.2
  • 15
    • 0029160765 scopus 로고
    • A biotechnological method provides access to aggregation component monomeric Alzheimer's 1-42 residue amyloid peptide
    • 15. Döbeli, H.; Draeger, N.; Huber, G.; Jakob, P.; et al. A biotechnological method provides access to aggregation component monomeric Alzheimer's 1-42 residue amyloid peptide. Biotechniques 13:988-993; 1995.
    • (1995) Biotechniques , vol.13 , pp. 988-993
    • Döbeli, H.1    Draeger, N.2    Huber, G.3    Jakob, P.4
  • 16
    • 0027258149 scopus 로고
    • Cells with a familial Alzheimer's disease mutation produce authentic β-peptide
    • 16. Dovey, H. F.; Suomensaari-Chrysler, S.; Lieberburg, I.; Sinha, S.; Keim, P. S. Cells with a familial Alzheimer's disease mutation produce authentic β-peptide. Neuroreport 4:1039-1042; 1993.
    • (1993) Neuroreport , vol.4 , pp. 1039-1042
    • Dovey, H.F.1    Suomensaari-Chrysler, S.2    Lieberburg, I.3    Sinha, S.4    Keim, P.S.5
  • 18
    • 0028872558 scopus 로고
    • Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implications for the pathogenesis and treatment of Alzheimer's disease
    • 18. Evans, K. C.; Berger, E. P.; Cho, C.-G.; Weisgraber, K. H.; Lansbury, P. T. Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implications for the pathogenesis and treatment of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 92:763-767; 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 763-767
    • Evans, K.C.1    Berger, E.P.2    Cho, C.-G.3    Weisgraber, K.H.4    Lansbury, P.T.5
  • 20
    • 0028981009 scopus 로고
    • Solubilization of β amyloid-(1-42) peptide: Reversing the β-sheet conformation induced by aluminum with silicates
    • 20. Fasman, G. D.; Perczel, A.; Moore, C. D. Solubilization of β amyloid-(1-42) peptide: Reversing the β-sheet conformation induced by aluminum with silicates. Proc. Natl. Acad. Sci. USA 92:369-371; 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 369-371
    • Fasman, G.D.1    Perczel, A.2    Moore, C.D.3
  • 22
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • 22. Glenner, G. G.; Wong, C. W. Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 122:885-890; 1984.
    • (1984) Biochem. Biophys. Res. Commun. , vol.122 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 23
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer disease
    • 23. Goate, A.; Chartier-Harlin, M.-C.; Mullan, M.; Brown, J.; Crawford, F.; Fidani, L.; Giuffra, L.; et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer disease. Nature 349:704-706; 1991.
    • (1991) Nature , vol.349 , pp. 704-706
    • Goate, A.1    Chartier-Harlin, M.-C.2    Mullan, M.3    Brown, J.4    Crawford, F.5    Fidani, L.6    Giuffra, L.7
  • 25
    • 0001360461 scopus 로고
    • Brain interleukin-1 and S100 immunoreactivity elevated in Down's syndrome and Alzheimer's disease
    • 25. Griffin, W. S. T.; Stanley, L. C.; Ling, C.; et al. Brain interleukin-1 and S100 immunoreactivity elevated in Down's syndrome and Alzheimer's disease. Proc. Natl. Acad. Sci. USA 86:7611-7615; 1989.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7611-7615
    • Griffin, W.S.T.1    Stanley, L.C.2    Ling, C.3
  • 26
    • 0028926976 scopus 로고
    • Interleukin-1 expression in different plaque types in Alzheimer's disease: Significance in plaque evolution
    • 26. Griffin, W. S. T.; Sheng, J. G.; Roberts, G. W.; Mrak, R. E. Interleukin-1 expression in different plaque types in Alzheimer's disease: Significance in plaque evolution. J. Neuropathol. Exp. Neurol. 54: 276-281; 1995.
    • (1995) J. Neuropathol. Exp. Neurol. , vol.54 , pp. 276-281
    • Griffin, W.S.T.1    Sheng, J.G.2    Roberts, G.W.3    Mrak, R.E.4
  • 27
    • 0026879650 scopus 로고
    • Presenile dementia and cerebral hemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene
    • 27. Hendriks, L.; Van Duijn, C. M.; Cras, P.; et al. Presenile dementia and cerebral hemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene. Nat. Genet. 1:218-221; 1992.
    • (1992) Nat. Genet. , vol.1 , pp. 218-221
    • Hendriks, L.1    Van Duijn, C.M.2    Cras, P.3
  • 28
    • 0028987849 scopus 로고
    • Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular site of catabolism
    • 28. Higaki, J.; Quon, D.; Zhong, Z.; Cordell, B. Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular site of catabolism. Neuron 14:651-659; 1995.
    • (1995) Neuron , vol.14 , pp. 651-659
    • Higaki, J.1    Quon, D.2    Zhong, Z.3    Cordell, B.4
  • 29
    • 0028899724 scopus 로고
    • Quantitative analysis of senile plaques in Alzheimer disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome)
    • 29. Hyman, B. T.; West, H. L.; Rebeck, G. W.; Buldyrev, S. V.; Mantegna, R. N.; Ukleja, M.; Havlin, S.; Stanley, H. E. Quantitative analysis of senile plaques in Alzheimer disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome). Proc. Natl. Acad. Sci. USA 92:3586-3590; 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3586-3590
    • Hyman, B.T.1    West, H.L.2    Rebeck, G.W.3    Buldyrev, S.V.4    Mantegna, R.N.5    Ukleja, M.6    Havlin, S.7    Stanley, H.E.8
  • 30
    • 0028169925 scopus 로고
    • Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)
    • 30. Iwatsubo, T.; Odaka, A.; Suzuki, N.; Mizusawa, H.; Nukina, N.; Ihara, Y. Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43). Neuron 13:45-53; 1994.
    • (1994) Neuron , vol.13 , pp. 45-53
    • Iwatsubo, T.1    Odaka, A.2    Suzuki, N.3    Mizusawa, H.4    Nukina, N.5    Ihara, Y.6
  • 31
    • 0027195933 scopus 로고
    • Seeding "one-dimensional crystalization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
    • 31. Jarrett, J. T.; Lansbury, P. T. Seeding "one-dimensional crystalization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73:1055-1058; 1993.
    • (1993) Cell , vol.73 , pp. 1055-1058
    • Jarrett, J.T.1    Lansbury, P.T.2
  • 32
    • 0027258525 scopus 로고
    • The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
    • 32. Jarrett, J. T.; Berger, E. P.; Lansbury, P. T. The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease. Biochemistry 32:4693-4697; 1993.
    • (1993) Biochemistry , vol.32 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury, P.T.3
  • 35
    • 0028913416 scopus 로고
    • Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: Implications for Alzheimer's disease
    • 35. Kisilevsky, R.; Lemieux, L. J.; Fraser, P. E.; Kong, X.; Hultin, P. G.; Szarek, W. A. Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: Implications for Alzheimer's disease. Nat. Med. 1:143-148; 1995.
    • (1995) Nat. Med. , vol.1 , pp. 143-148
    • Kisilevsky, R.1    Lemieux, L.J.2    Fraser, P.E.3    Kong, X.4    Hultin, P.G.5    Szarek, W.A.6
  • 37
    • 0028286934 scopus 로고
    • Lack of association between apolipoprotein E allele E4 and sporadic Alzheimer's disease
    • 37. Lannfelt, L.; Lilius, L.; Nastase, M.; Viitanen, M.; et al. Lack of association between apolipoprotein E allele E4 and sporadic Alzheimer's disease. Neurosci. Lett. 169:175-178; 1994.
    • (1994) Neurosci. Lett. , vol.169 , pp. 175-178
    • Lannfelt, L.1    Lilius, L.2    Nastase, M.3    Viitanen, M.4
  • 41
    • 0029618686 scopus 로고
    • A potential familial Alzheimer's disease gene on chromosome 1 related to AD3
    • 41. Li, J.; Ma, J.; Potter, H. A potential familial Alzheimer's disease gene on chromosome 1 related to AD3. Proc. Natl. Acad. Sci. USA 92: 12180-12184; 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12180-12184
    • Li, J.1    Ma, J.2    Potter, H.3
  • 42
    • 0027717482 scopus 로고
    • Characterization of amyloid fibril β-peptide in familial Alzheimer's disease with APP717 mutations
    • 42. Liepnieks, J. J.; Ghetti, B.; Farlow, M.; Roses, A. D.; Benson, M. D. Characterization of amyloid fibril β-peptide in familial Alzheimer's disease with APP717 mutations. Biochem. Biophys. Res. Commun. 197:386-392; 1993.
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 386-392
    • Liepnieks, J.J.1    Ghetti, B.2    Farlow, M.3    Roses, A.D.4    Benson, M.D.5
  • 43
    • 0028172886 scopus 로고
    • β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo Red
    • 43. Lorenzo, A.; Yankner, B. A. β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo Red. Proc. Natl. Acad. Sci. USA 91:12243-12247; 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12243-12247
    • Lorenzo, A.1    Yankner, B.A.2
  • 44
    • 0028173205 scopus 로고
    • 1antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
    • 1antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 372:92-94; 1994.
    • (1994) Nature , vol.372 , pp. 92-94
    • Ma, J.1    Yee, A.2    Brewer, H.B.3    Das, S.4    Potter, H.5
  • 45
    • 0028816355 scopus 로고
    • Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotype risks
    • 45. Maestre, G.; Ottman, R.; Stern, Y.; Gurland, B.; et al. Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotype risks. Ann. Neurol. 37:254-259; 1995.
    • (1995) Ann. Neurol. , vol.37 , pp. 254-259
    • Maestre, G.1    Ottman, R.2    Stern, Y.3    Gurland, B.4
  • 46
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • 46. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63; 1983.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 47
    • 0026907151 scopus 로고
    • A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
    • 47. Mullan, M.; Crawford, F.; Axelman, K.; Houlden, H.; Lulius, L.; Winblad, B.; Lannfelt, L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid. Nat. Genet. 1:345-347; 1992.
    • (1992) Nat. Genet. , vol.1 , pp. 345-347
    • Mullan, M.1    Crawford, F.2    Axelman, K.3    Houlden, H.4    Lulius, L.5    Winblad, B.6    Lannfelt, L.7
  • 48
    • 0025971426 scopus 로고
    • Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
    • 48. Namba, Y.; Tomonaga, M.; Kawasaki, H.; Otomon, E.; Ikeda, K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. 541:163-166; 1991.
    • (1991) Brain Res. , vol.541 , pp. 163-166
    • Namba, Y.1    Tomonaga, M.2    Kawasaki, H.3    Otomon, E.4    Ikeda, K.5
  • 49
    • 0028106152 scopus 로고
    • Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer disease and normal aging
    • 49. Näslund, J.; Schierhorn, A.; Hellman, U.; Lannfelt, L.; Roses, A. D.; et al. Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer disease and normal aging. Proc. Natl. Acad. Sci. USA 91:8378-8382; 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8378-8382
    • Näslund, J.1    Schierhorn, A.2    Hellman, U.3    Lannfelt, L.4    Roses, A.D.5
  • 50
    • 0029043032 scopus 로고
    • Apolipoprotein E polymorphism influences not only cerebral senile plaque load but also Alzheimer-type neurofibrillary tangle formation
    • 50. Ohm, T. G.; Kirca, M.; Bohl, J.; Scharnagl, H.; Groß, W.; März, W. Apolipoprotein E polymorphism influences not only cerebral senile plaque load but also Alzheimer-type neurofibrillary tangle formation. Neuroscience 66:583-587; 1995.
    • (1995) Neuroscience , vol.66 , pp. 583-587
    • Ohm, T.G.1    Kirca, M.2    Bohl, J.3    Scharnagl, H.4    Groß, W.5    März, W.6
  • 52
    • 0025735884 scopus 로고
    • Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage
    • 52. Pericak-Vance, M. A.; Bebout, J. L.; Gaskell, P. C.; Yamaoka, L. H.; et al. Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage. Am. J. Hum. Genet. 48:1034-1050; 1991.
    • (1991) Am. J. Hum. Genet. , vol.48 , pp. 1034-1050
    • Pericak-Vance, M.A.1    Bebout, J.L.2    Gaskell, P.C.3    Yamaoka, L.H.4
  • 54
    • 0025992417 scopus 로고
    • In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity
    • 54. Pike, C. J.; Walencewicz, A. J.; Glabe, C. G.; Cotman, C. W. In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563:311-314; 1991.
    • (1991) Brain Res. , vol.563 , pp. 311-314
    • Pike, C.J.1    Walencewicz, A.J.2    Glabe, C.G.3    Cotman, C.W.4
  • 55
    • 0027447286 scopus 로고
    • Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
    • 55. Pike, C. J.; Burdick, D.; Walencewicz, A. J.; Glabe, C. G.; Cotman, C. W. Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state. J. Neurosci. 13:1676-1687; 1993.
    • (1993) J. Neurosci. , vol.13 , pp. 1676-1687
    • Pike, C.J.1    Burdick, D.2    Walencewicz, A.J.3    Glabe, C.G.4    Cotman, C.W.5
  • 57
    • 0002742452 scopus 로고
    • 1antichymotrypsin and β-protein form a stable complex in vitro
    • Iqbal, K.; MacLachlan, D. R. C.; Winblad, B.; Wisniewski, H. M., eds. New York: John Wiley & Sons
    • 1antichymotrypsin and β-protein form a stable complex in vitro. In: Iqbal, K.; MacLachlan, D. R. C.; Winblad, B.; Wisniewski, H. M., eds. Alzheimer's disease: Basic mechanisms, diagnosis, and therapeutic strategies. New York: John Wiley & Sons; 1991:275-279.
    • (1991) Alzheimer's Disease: Basic Mechanisms, Diagnosis, and Therapeutic Strategies , pp. 275-279
    • Potter, H.1    Abraham, C.R.2    Dressier, D.3
  • 58
    • 0027082694 scopus 로고
    • The involvement of proteases, protease inhibitors, and an acute phase response in Alzheimer's disease
    • 58. Potter, H.; Nelson, R. B.; Das, S.; Siman, R.; Kayyali, U. S.; Dressler, D. The involvement of proteases, protease inhibitors, and an acute phase response in Alzheimer's disease. Ann. NY Acad. Sci. 674:161-173; 1992.
    • (1992) Ann. NY Acad. Sci. , vol.674 , pp. 161-173
    • Potter, H.1    Nelson, R.B.2    Das, S.3    Siman, R.4    Kayyali, U.S.5    Dressler, D.6
  • 59
    • 0001421726 scopus 로고
    • Beyond β-protein: New steps in the pathogenic pathway to Alzheimer's disease
    • Iqbal, K.; Mortimer, J. A.; Winblad, B.; Wisniewski, W. H., eds. New York: John Wiley & Sons
    • 59. Potter, H.; Ma, J.; Das, S.; Geller, L. N.; Benjamin, M.; Kayyali. U. S.; Dressler, D. Beyond β-protein: New steps in the pathogenic pathway to Alzheimer's disease. In: Iqbal, K.; Mortimer, J. A.; Winblad, B.; Wisniewski, W. H., eds. Research advances in Alzheimer's disease and related disorders. New York: John Wiley & Sons; 1995:643-654.
    • (1995) Research Advances in Alzheimer's Disease and Related Disorders , pp. 643-654
    • Potter, H.1    Ma, J.2    Das, S.3    Geller, L.N.4    Benjamin, M.5    Kayyali, U.S.6    Dressler, D.7
  • 60
    • 0027374047 scopus 로고
    • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • 60. Rebeck, G. W.; Reiter, J. S.; Strickland, D. K.; Hyman, B. T. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions. Neuron 11:575-580; 1993.
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3    Hyman, B.T.4
  • 62
    • 0027332081 scopus 로고
    • β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer's disease
    • 62. Roher, A. E.; Lowenson, J. D.; Clarke, S.; Woods, A. S.; Cotter, R. J.; Gowing, E.; Ball, M. J. β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 90:10836-10840; 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10836-10840
    • Roher, A.E.1    Lowenson, J.D.2    Clarke, S.3    Woods, A.S.4    Cotter, R.J.5    Gowing, E.6    Ball, M.J.7
  • 63
    • 0025002021 scopus 로고
    • Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease
    • 63. Rozemuller, J. M.; Stam, F. C.; Eikelenboom, P. Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease. Neurosci. Lett. 119:75-78; 1990.
    • (1990) Neurosci. Lett. , vol.119 , pp. 75-78
    • Rozemuller, J.M.1    Stam, F.C.2    Eikelenboom, P.3
  • 65
    • 0028026587 scopus 로고
    • Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils
    • 65. Sanan, D. A.; Weisgraber, K. H.; Russell, S. J.; Mahley, R. W.; Huang, D.; et al. Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils. J. Clin. Invest. 94:860-869; 1994.
    • (1994) J. Clin. Invest. , vol.94 , pp. 860-869
    • Sanan, D.A.1    Weisgraber, K.H.2    Russell, S.J.3    Mahley, R.W.4    Huang, D.5
  • 66
    • 0029073383 scopus 로고
    • Genetic dissection of Alzheimer disease, a heterogeneous disorder
    • 66. Schellenberg, G. D. Genetic dissection of Alzheimer disease, a heterogeneous disorder. Proc. Natl. Acad. Sci. USA 92:8552-8559; 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8552-8559
    • Schellenberg, G.D.1
  • 68
    • 0027365822 scopus 로고
    • Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
    • 68. Schmechel, D. E.; Saunders, A. M.; Strittmatter, W. J.; Grain, B. J.; et al. Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:9649-9653;1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9649-9653
    • Schmechel, D.E.1    Saunders, A.M.2    Strittmatter, W.J.3    Grain, B.J.4
  • 69
    • 0027999030 scopus 로고
    • Transthyretin sequesters amyloid β protein and prevents amyloid formation
    • 69. Schwartzman, A. L.; Gregori, L.; Vitek, M. P.; Lyubski, S.; et al. Transthyretin sequesters amyloid β protein and prevents amyloid formation. Proc. Natl. Acad. Sci. USA 91:8368-8372; 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8368-8372
    • Schwartzman, A.L.1    Gregori, L.2    Vitek, M.P.3    Lyubski, S.4
  • 70
    • 0028170818 scopus 로고
    • Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease
    • 70. Selkoe, D. J. Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10:373-403; 1994.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 373-403
    • Selkoe, D.J.1
  • 71
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutations in early onset familial Alzheimer's disease
    • 71. Sherrington, R.; Rogaev, E. I.; Liang, Y.; Rogaeva, E. A.; Levesque, G.; et al. Cloning of a gene bearing missense mutations in early onset familial Alzheimer's disease. Nature 375:754-760; 1995.
    • (1995) Nature , vol.375 , pp. 754-760
    • Sherrington, R.1    Rogaev, E.I.2    Liang, Y.3    Rogaeva, E.A.4    Levesque, G.5
  • 73
    • 0001744084 scopus 로고
    • Plasma amyloid β-protein (Aβ) ending at Aβ42(43) is increased in carriers of familial AD (FAD) linked to chromosome 14
    • 73. Song, X.-H.; Suzuki, N.; Bird, T.; Peskind, E.; Schellenberg. G. D.; Younkin, S. G. Plasma amyloid β-protein (Aβ) ending at Aβ42(43) is increased in carriers of familial AD (FAD) linked to chromosome 14. Soc. Neurosci. Abstr. 21:1501; 1995.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 1501
    • Song, X.-H.1    Suzuki, N.2    Bird, T.3    Peskind, E.4    Schellenberg, G.D.5    Younkin, S.G.6
  • 74
    • 0027032695 scopus 로고
    • Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14
    • 74. St. George-Hyslop, P.; Haines, J.; Rogaev, E.; Mortilla, M.; Vaula, G.; et al. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nat. Genet. 2:330-334; 1992.
    • (1992) Nat. Genet. , vol.2 , pp. 330-334
    • St. George-Hyslop, P.1    Haines, J.2    Rogaev, E.3    Mortilla, M.4    Vaula, G.5
  • 76
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid β-protein by familial amyloid β-protein precursor (βAPP717) mutants
    • 76. Suzuki, N.; Cheung, T. T.; Cai, M.-D.; Odaka, A.; Otvos, L.; Eckman, C.; Golde, T. E.; Younkin, S. G. An increased percentage of long amyloid β-protein by familial amyloid β-protein precursor (βAPP717) mutants. Science 264:1336-1340; 1994.
    • (1994) Science , vol.264 , pp. 1336-1340
    • Suzuki, N.1    Cheung, T.T.2    Cai, M.-D.3    Odaka, A.4    Otvos, L.5    Eckman, C.6    Golde, T.E.7    Younkin, S.G.8
  • 78
    • 0028331604 scopus 로고
    • Amyloid β protein-induced neuronal cell death: Neurotoxic properties of aggregated amyloid β protein
    • 78. Ueda, K.; Fukui, Y.; Kageyama, H. Amyloid β protein-induced neuronal cell death: Neurotoxic properties of aggregated amyloid β protein. Brain Res. 639:240-244; 1994.
    • (1994) Brain Res. , vol.639 , pp. 240-244
    • Ueda, K.1    Fukui, Y.2    Kageyama, H.3
  • 81
    • 0028350675 scopus 로고
    • ApoE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease
    • 81. Van Broeckhoven, C.; Backhovens, H.; Cruts, M.; Martin, J. J.; Crook, R.; Houlden, H.; Hardy, J. ApoE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease. Neurosci. Lett. 169:179-180; 1994.
    • (1994) Neurosci. Lett. , vol.169 , pp. 179-180
    • Van Broeckhoven, C.1    Backhovens, H.2    Cruts, M.3    Martin, J.J.4    Crook, R.5    Houlden, H.6    Hardy, J.7
  • 82
    • 0028988736 scopus 로고
    • The apolipoprotein E ∈2 allele is associated with an increased risk of early onset Alzheimer's disease and a reduced survival
    • 82. Van Duijn, C. M.; de Knijff, P.; Wehnert, A.; De Voecht, J.; et al. The apolipoprotein E ∈2 allele is associated with an increased risk of early onset Alzheimer's disease and a reduced survival. Ann. Neurol. 37: 605-610; 1995.
    • (1995) Ann. Neurol. , vol.37 , pp. 605-610
    • Van Duijn, C.M.1    De Knijff, P.2    Wehnert, A.3    De Voecht, J.4
  • 83
    • 0026045862 scopus 로고
    • Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation
    • 83. Wisniewski, T.; Ghiso, J.; Frangione, B. Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochem. Biophys. Res. Commun. 179:1247-1254; 1991.
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 1247-1254
    • Wisniewski, T.1    Ghiso, J.2    Frangione, B.3
  • 84
    • 0026542786 scopus 로고
    • Apolipoprotein E: A pathologic chaperone in patients with cerebral and systemic amyloid
    • 84. Wisniewski, T.; Frangione, B. Apolipoprotein E: A pathologic chaperone in patients with cerebral and systemic amyloid. Neurosci. Lett. 135:235-238; 1992.
    • (1992) Neurosci. Lett. , vol.135 , pp. 235-238
    • Wisniewski, T.1    Frangione, B.2
  • 86
    • 0027970307 scopus 로고
    • Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro
    • 86. Wisniewski, T.; Castaño, E. M.; Golabek, A.; Vogel, T.; Frangione, B. Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am. J. Pathol. 145:1030-1035; 1994.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1030-1035
    • Wisniewski, T.1    Castaño, E.M.2    Golabek, A.3    Vogel, T.4    Frangione, B.5
  • 87
    • 0026432318 scopus 로고
    • β-Amyloid and the pathogenesis of Alzheimer's disease
    • 87. Yankner, B. A.; Mesulam, M.-M. β-Amyloid and the pathogenesis of Alzheimer's disease. N. Engl. J. Med. 325:1849; 1991.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1849
    • Yankner, B.A.1    Mesulam, M.-M.2
  • 88
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid β-protein: Reversal by tachykinin neuro-peptides
    • 88. Yankner, B. A.; Duffy, L. K.; Kirschner, D. A. Neurotrophic and neurotoxic effects of amyloid β-protein: Reversal by tachykinin neuro-peptides. Science 250:280-282; 1990.
    • (1990) Science , vol.250 , pp. 280-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3


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