Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and microRNA biogenesis

Journal of Virology

Volumn 78, Issue 23, 2004, Pages 12868-12876

  Lu, Shihua ^a   Cullen, Bryan R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; DICER; EXPORTIN 1; GENE PRODUCT; MICRORNA; NUCLEAR FACTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS RNA;

ADENOVIRUS; ARTICLE; BIOGENESIS; CELL CULTURE; HUMAN; HUMAN CELL; IMMUNITY; INFECTION RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; RNA INTERFERENCE; RNA SYNTHESIS; RNA TRANSPORT; RNA VECTOR; VIRAL GENE DELIVERY SYSTEM; VIRUS GENE; VIRUS INFECTION; VIRUS INHIBITION;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOVIRIDAE; CELL LINE; EIF-2 KINASE; HUMANS; MICRORNAS; RIBONUCLEASE III; RNA, SMALL INTERFERING; RNA, VIRAL;

EID: 8644247492     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.23.12868-12876.2004     Document Type: Article

References (41)

1. Arts, G.-J., E. Langemeijer, R. Tissingh, L. Ma, H. Pavliska, K. Dokic, R. Dooijes, E. Mešić, R. Clasen, F. Michiels, J. van der Schueren, M. Lambrecht, S. Herman, R. Brys, K. Thys, M. Hoffmann, P. Tomme, and H. van Es. 2003. Adenoviral vectors expressing siRNAs for discovery and validation of gene function. Genome Res. 13:2325-2332.
2. Bartel, D. P. 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
3. Bernstein, E., A. A. Caudy, S. M. Hammond, and G. J. Hannon. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:295-296.
4. Bridge, A. J., S. Pebernard, A. Ducraux, A.-L. Nicoulaz, and R. Iggo. 2003. Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. 34:263-264.
5. Brummelkamp, T., R. Bernards, and R. Agami. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553.
6. Carrington, J. C., K. D. Kasschau, and L. K. Johansen. 2001. Activation and suppression of RNA silencing by plant viruses. Virology 281:1-5.
7. Coburn, G. A., H. L. Wiegand, Y. Kang, D. N. Ho, M. M. Georgiadis, and B. R. Cullen. 2001. Using viral species specificity to define a critical protein/RNA interaction surface. Genes Dev. 15:1194-1205.
8. Doench, J. G., C. P. Petersen, and P. A. Sharp. 2003. siRNAs can function as miRNAs. Genes Dev. 17:438-442.
9. Dykxhoorn, D. M., C. D. Novina, and P. A. Sharp. 2003. Killing the messenger: short RNAs that silence gene expression. Nature Rev. 4:457-467.
10. Elbashir, S. M., J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-498.
11. Gitlin, L., and R. Andino. 2003. Nucleic acid-based immune system: the antiviral potential of mammalian RNA silencing. J. Virol. 77:7159-7165.
12. Gwizdek, C., B. Ossarch-Nazari, A. M. Brownawell, A. Doglio, E. Bertrand, I. G. Macara, and C. Dargemont. 2003. Exportin-5 mediates nuclear export of minihelix-containing RNAs. J. Biol. Chem. 278:5505-5508.
13. Hammond, S. M., E. Bernstein, D. Beach, and G. J. Hannon. 2000. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404:293-295.
14. Hannon, G. J. 2002. RNA interference. Nature 418:244-251.
15. Hutvágner, G., J. McLachlan, A. E. Pasquinelli, É. Bálint, T. Tuschl, and P. D. Zamore. 2001. A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA. Science 293:834-838.
16. Hutvágner, G., and P. D. Zamore. 2002. A microRNA in a multiple-turnover RNAi enzyme complex. Science 297:2056-2060.
17. Kaufman, R. J., and P. Murtha. 1987. Translational control mediated by eucaryotic initiation factor-2 is restricted to specific mRNAs in transfected cells. Mol. Cell. Biol. 7:1568-1571.
18. Ketting, R. F., S. E. Fischer, E. Bernstein, T. Sijen, G. J. Hannon, and R. H. Plasterk, 2001. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15:2654-2659.
19. Lee, Y., C. Ahn, J. Han, H. Choi, J. Kim, J. Yim, J. Lee, P. Provost, O. Rådmark, S. Kim, and V. N. Kim. 2003. The nuclear RNase III Drosha initiates microRNA processing. Nature 425:415-419.
20. Lee, Y., K. Jeon, J.-T. Lee, S. Kim, and V. N. Kim. 2002. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21:4663-4670.
21. Li, H., W. X. Li, and S. W. Ding. 2002. Induction and suppression of RNA silencing by an animal virus. Science 296:1319-1321.
22. Li, W.-X., H. Li, R. Lu, F. Li, M. Dus, P. Atkinson, E. W. A. Brydon, K. L. Johnson, A. Garcia-Sastre, L. A. Ball, P. Palese, and S.-W. Ding. 2004. Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc. Natl. Acad. Sci. USA 101:1350-1355.
23. Lu, S., and B. R. Cullen. 2003. Analysis of the stimulatory effect of splicing on mRNA production and utilization in mammalian cells. RNA 9:618-630.
24. Lund, E., S. Güttinger, A. Calado, J. E. Dahlberg, and U. Kutay. 2004. Nuclear export of microRNA precursors. Science 303:95-98.
25. 1. Virology 164:106-113.
26. Martinez, J., A. Patkaniowska, H. Urlaub, R. Lührmann, and T. Tuschl. 2002. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110:563-574.
27. Mathews, M. B., and T. Shenk. 1991. Adenovirus virus-associated RNA and translation control. J. Virol. 65:5657-5662.
28. Paddison, P. J., A. A. Caudy, E. Bernstein, G. J. Hannon, and D. S. Conklin. 2002. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16:948-958.
29. Schwarz, D. S., G. Hutvágner, T. Du, Z. Xu, N. Aronin, and P. D. Zamore. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115:199-208.
30. Schwarz, D. S., G. Hutvágner, B. Haley, and P. D. Zamore. 2002. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol. Cell 10:537-548.
31. Shen, C., A. K. Buck, X. Liu, M. Winkler, and S. N. Reske. 2003. Gene silencing by adenovirus-delivered siRNA. FEBS Lett. 539:111-114.
32. Simons, F. H., S. A. Rutjes, W. J. van Venrooij, and G. J. Pruijn. 1996. The interactions with Ro60 and La differentially affect nuclear export of hY1 RNA. RNA 2:264-273.
33. Sledz, C. A., M. Holko, M. J. De Veer, R. H. Silverman, and B. R. Williams. 2003. Activation of the interferon system by short-interfering RNAs. Nat. Cell Biol. 5:834-839.
34. Strijker, R., D. T. Fritz, and A. D. Levinson. 1989. Adenovirus VAI-RNA regulates gene expression by controlling stability of ribosome-bound RNAs. EMBO J. 8:2669-2675.
35. Svensson, C., and G. Akusjarvi. 1990. A novel effect of adenovirus VA RNA1 on cytoplasmic mRNA abundance. Virology 174:613-617.
36. Thimmappaya, B., C. Weinberger, R. J. Schneider, and T. Shenk. 1982. Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection. Cell 31:543-551.
37. Tiscornia, G., O. Singer, M. Ikawa, and I. M. Verma. 2003. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA 100:1844-1848.
38. Wolin, S. L., and T. Cedervall. 2002. The LA protein. Annu. Rev. Biochem. 71:375-403.
39. Yi, R., Y. Qin, I. G. Macara, and B. R. Cullen. 2003. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17:3011-3016.
40. Zeng, Y., and B. R. Cullen. 2003. Sequence requirements for micro RNA processing and function in human cells. RNA 9:112-123.
41. Zeng, Y., R. Yi, and B. R. Cullen. 2003. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc. Natl. Acad. Sci. USA 100:9779-9784.