-
3
-
-
0036221744
-
Gastrointestinal cancer of the microsatellite mutator phenotype pathway
-
Yamamoto H, Imai K, Perucho M. Gastrointestinal cancer of the microsatellite mutator phenotype pathway. J Gastroenterol 2002;37:153-63.
-
(2002)
J Gastroenterol
, vol.37
, pp. 153-163
-
-
Yamamoto, H.1
Imai, K.2
Perucho, M.3
-
4
-
-
0037178722
-
Maintenance of genome stability in Saccharomyces cerevisiae
-
Kolodner RD, Putnam CD, Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science 2002;297:552-7.
-
(2002)
Science
, vol.297
, pp. 552-557
-
-
Kolodner, R.D.1
Putnam, C.D.2
Myung, K.3
-
5
-
-
0035289717
-
Chromosomal stability and the DNA double-strand break connection
-
van Gent DC, Hoeijmakers JHJ, Kanaar R. Chromosomal stability and the DNA double-strand break connection. Nat Rev Genet 2001;2:196-206.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 196-206
-
-
Van Gent, D.C.1
Hoeijmakers, J.H.J.2
Kanaar, R.3
-
6
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou B-BS, Iledge SJ. The DNA damage response: putting checkpoints in perspective. Nature 2000;408:433-9.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.-B.S.1
Iledge, S.J.2
-
7
-
-
0037660900
-
The role of DNA breaks in genomic instability and tumorigenesis
-
Mills KD, Ferguson DO, Alt FW. The role of DNA breaks in genomic instability and tumorigenesis. Immunol Rev 2003;194:77-95.
-
(2003)
Immunol Rev
, vol.194
, pp. 77-95
-
-
Mills, K.D.1
Ferguson, D.O.2
Alt, F.W.3
-
8
-
-
0036261707
-
Sensing and repairing DNA double-strand breaks
-
Jackson SP. Sensing and repairing DNA double-strand breaks. Carcinogenesis 2002;23:687-96.
-
(2002)
Carcinogenesis
, vol.23
, pp. 687-696
-
-
Jackson, S.P.1
-
9
-
-
0942268167
-
Repair of DNA double strand breaks by nonhomologous end joining
-
Lees-Miller SP, Meek K. Repair of DNA double strand breaks by nonhomologous end joining. Biochimie 2003;85:1161-73.
-
(2003)
Biochimie
, vol.85
, pp. 1161-1173
-
-
Lees-Miller, S.P.1
Meek, K.2
-
10
-
-
3242886313
-
Homologous recombination-mediated double-strand break repair
-
Wyman C, Ristic D, Kanaar R. Homologous recombination-mediated double-strand break repair. DNA Repair 2004;3:827-33.
-
(2004)
DNA Repair
, vol.3
, pp. 827-833
-
-
Wyman, C.1
Ristic, D.2
Kanaar, R.3
-
11
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003;3:155-68.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
12
-
-
0037115915
-
The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans
-
Moynahan ME. The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans. Oncogene 2002;21:8994-9007.
-
(2002)
Oncogene
, vol.21
, pp. 8994-9007
-
-
Moynahan, M.E.1
-
13
-
-
0036727417
-
Mice heterozygous for mutation in ATM, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer
-
Spring K, Ahangari F, Scott SP, et al. Mice heterozygous for mutation in ATM, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer. Nat Genet 2002;32:185-90.
-
(2002)
Nat Genet
, vol.32
, pp. 185-190
-
-
Spring, K.1
Ahangari, F.2
Scott, S.P.3
-
14
-
-
0034732239
-
DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
-
Difilippantonio MJ, Zhu J, Chen HT, et al. DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation. Nature 2000;404:510-4.
-
(2000)
Nature
, vol.404
, pp. 510-514
-
-
Difilippantonio, M.J.1
Zhu, J.2
Chen, H.T.3
-
15
-
-
0030885974
-
Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination in vivo
-
Ouyang H, Nussenzweig A, Kurimasa A, et al. Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination in vivo. J Exp Med 1997;186:921-9.
-
(1997)
J Exp Med
, vol.186
, pp. 921-929
-
-
Ouyang, H.1
Nussenzweig, A.2
Kurimasa, A.3
-
16
-
-
0033523268
-
Cancer risks in BRCA2 mutation carriers
-
Breast Cancer Linkage Consortium T. Cancer risks in BRCA2 mutation carriers. J Natl Cancer Inst 1999;91:1310-6.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1310-1316
-
-
-
17
-
-
0035098503
-
Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
-
Risch HA, McLaughlin JR, Cole DE, et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am J Hum Genet 2001;68:700-10.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 700-710
-
-
Risch, H.A.1
McLaughlin, J.R.2
Cole, D.E.3
-
18
-
-
0037130887
-
Cancer incidence in BRCA1 mutation carriers
-
Thompson D, Easton DF. Cancer incidence in BRCA1 mutation carriers. J Natl Cancer Inst 2002;94:1358-65.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1358-1365
-
-
Thompson, D.1
Easton, D.F.2
-
19
-
-
0037130889
-
Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program
-
Brose MS, Rebbeck TR, Calzone KA, et al. Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program. J Natl Cancer Inst 2002;94:1365-72.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1365-1372
-
-
Brose, M.S.1
Rebbeck, T.R.2
Calzone, K.A.3
-
20
-
-
0842302522
-
BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer
-
Niell BL, Rennen G, Bonner JD, et al. BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. J Natl Cancer Inst 2004;96:15-21.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 15-21
-
-
Niell, B.L.1
Rennen, G.2
Bonner, J.D.3
-
21
-
-
10744225854
-
Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer
-
Kirchhoff T, Satagopan JM, Kauff ND, et al. Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer. J Natl Cancer Inst 2004;96:68-70.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 68-70
-
-
Kirchhoff, T.1
Satagopan, J.M.2
Kauff, N.D.3
-
22
-
-
10744232674
-
Prognostic significance of the allelic loss of the BRCA1 gene in colorectal cancer
-
Garcia JM, Rodriguez R, Dominguez G, et al. Prognostic significance of the allelic loss of the BRCA1 gene in colorectal cancer. Gut 2003;52:1756-63.
-
(2003)
Gut
, vol.52
, pp. 1756-1763
-
-
Garcia, J.M.1
Rodriguez, R.2
Dominguez, G.3
-
23
-
-
0033124632
-
Loss of heterozygosity at the ATM locus in colorectal carcinoma
-
Uhrhammer N, Bay J, Pernin D, et al. Loss of heterozygosity at the ATM locus in colorectal carcinoma. Oncol Rep 1999;6:655-8.
-
(1999)
Oncol Rep
, vol.6
, pp. 655-658
-
-
Uhrhammer, N.1
Bay, J.2
Pernin, D.3
-
24
-
-
0033564102
-
Identification of a region of frequent loss of heterozygosity at 11q24 in colorectal cancer
-
Connolly KC, Gabra H, Millwater CJ, et al. Identification of a region of frequent loss of heterozygosity at 11q24 in colorectal cancer. Cancer Res 1999;59:2806-9.
-
(1999)
Cancer Res
, vol.59
, pp. 2806-2809
-
-
Connolly, K.C.1
Gabra, H.2
Millwater, C.J.3
-
25
-
-
0035921688
-
Frequent allelic imbalance at the ATM locus in DNA multiploid colorectal carcinomas
-
Sugai T, Habano W, Uesugi N, et al. Frequent allelic imbalance at the ATM locus in DNA multiploid colorectal carcinomas. Oncogene 2001;20:6095-101.
-
(2001)
Oncogene
, vol.20
, pp. 6095-6101
-
-
Sugai, T.1
Habano, W.2
Uesugi, N.3
-
26
-
-
7044232415
-
Promoterhypermethylation of tumor-related genes in the progression of colorectal neoplasia
-
Bai AHC, Tong JHM, To K-F, et al. Promoterhypermethylation of tumor-related genes in the progression of colorectal neoplasia. Int J Cancer 2004;112:846-53.
-
(2004)
Int J Cancer
, vol.112
, pp. 846-853
-
-
Bai, A.H.C.1
Tong, J.H.M.2
To, K.-F.3
-
27
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J, Horejsi Z, Koed K, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005;434:864-70.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
-
28
-
-
0035576819
-
Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis
-
Rigas B, Borgo S, Elhosseiny A, et al. Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis. Cancer Res 2001;61:8381-4.
-
(2001)
Cancer Res
, vol.61
, pp. 8381-8384
-
-
Rigas, B.1
Borgo, S.2
Elhosseiny, A.3
-
29
-
-
16644391541
-
Upregulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer
-
Hosoi Y, Watanabe T, Nakagawa K, et al. Upregulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer. Int J Oncol 2004;25:461-8.
-
(2004)
Int J Oncol
, vol.25
, pp. 461-468
-
-
Hosoi, Y.1
Watanabe, T.2
Nakagawa, K.3
-
30
-
-
0037105408
-
The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinoma
-
Komuro Y, Watanabe T, Hosoi Y, et al. The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinoma. Cancer 2002;95:1199-205.
-
(2002)
Cancer
, vol.95
, pp. 1199-1205
-
-
Komuro, Y.1
Watanabe, T.2
Hosoi, Y.3
-
34
-
-
1142275106
-
Expression of BUB1 protein in gastric cancer correlates with the histological subtype, but not with DNA ploidy or microsatellite instability
-
Grabsch HI, Askham JM, Morrison EE, et al. Expression of BUB1 protein in gastric cancer correlates with the histological subtype, but not with DNA ploidy or microsatellite instability. J Pathol 2004;202:208-14.
-
(2004)
J Pathol
, vol.202
, pp. 208-214
-
-
Grabsch, H.I.1
Askham, J.M.2
Morrison, E.E.3
-
35
-
-
0029766176
-
Immunohistochemical study on the prognostic value of MIB-1 in gastric carcinoma
-
Muller W, Schneiders A, Meier S, Hommel G, Gabbert H. Immunohistochemical study on the prognostic value of MIB-1 in gastric carcinoma. Br J Cancer 1996;74:759-65.
-
(1996)
Br J Cancer
, vol.74
, pp. 759-765
-
-
Muller, W.1
Schneiders, A.2
Meier, S.3
Hommel, G.4
Gabbert, H.5
-
36
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan E, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-81.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.1
Meier, P.2
-
37
-
-
0000336139
-
Regression models and life-tables
-
Cox D. Regression models and life-tables. J R Stat Soc 1972;34:187-220.
-
(1972)
J R Stat Soc
, vol.34
, pp. 187-220
-
-
Cox, D.1
-
38
-
-
0142025259
-
Interactive competition between homologous recombination and non-homologous end joining
-
Allen C, Halbrook J, Nickoloff JA. Interactive competition between homologous recombination and non-homologous end joining. Mol Cancer Res 2003;1:913-20.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 913-920
-
-
Allen, C.1
Halbrook, J.2
Nickoloff, J.A.3
-
39
-
-
0034910515
-
Localization of human BRCA1 and BRCA2 in non-inherited colorectal carcinomas and matched normal mucosas
-
Bernard-Gallon D, Peffault de Latour M, Hizel C, et al. Localization of human BRCA1 and BRCA2 in non-inherited colorectal carcinomas and matched normal mucosas. Anticancer Res 2001;21:2011-20.
-
(2001)
Anticancer Res
, vol.21
, pp. 2011-2020
-
-
Bernard-Gallon, D.1
Peffault De Latour, M.2
Hizel, C.3
-
40
-
-
20944439681
-
The GADD45, ZBRK1 and BRCA1 pathway: Quantitative analysis of mRNA expression in colon carcinomas
-
Garcia V, Garcia JM, Pena C, et al. The GADD45, ZBRK1 and BRCA1 pathway: quantitative analysis of mRNA expression in colon carcinomas. J Pathol 2005;206:92-9.
-
(2005)
J Pathol
, vol.206
, pp. 92-99
-
-
Garcia, V.1
Garcia, J.M.2
Pena, C.3
-
41
-
-
10744225648
-
Deoxycholate, an endogenous tumour promoter and DNA damaging agent, modulates BRCA1 expression in apoptosis-sensitive epithelial cells: Loss of BRCA1 expression in colonic adenocarcinomas
-
Romagnolo DF, Chirnomas RB, Ku J, et al. Deoxycholate, an endogenous tumour promoter and DNA damaging agent, modulates BRCA1 expression in apoptosis-sensitive epithelial cells: loss of BRCA1 expression in colonic adenocarcinomas. Nutr Cancer 2003;46:82-92.
-
(2003)
Nutr Cancer
, vol.46
, pp. 82-92
-
-
Romagnolo, D.F.1
Chirnomas, R.B.2
Ku, J.3
-
42
-
-
0035135548
-
Frameshift mutations at coding mononucleotide repeats of the MRAD50 gene in gastrointestinal carcinomas with microsatellite instability
-
Kim N-G, Choi YR, Baek MJ, et al. Frameshift mutations at coding mononucleotide repeats of the MRAD50 gene in gastrointestinal carcinomas with microsatellite instability. Cancer Res 2001;61:36-8.
-
(2001)
Cancer Res
, vol.61
, pp. 36-38
-
-
Kim, N.-G.1
Choi, Y.R.2
Baek, M.J.3
-
43
-
-
0034028409
-
Aberrant splicing of the ATM gene associated with shortening of the intronic mononucleotide tract in human colon tumor cell lines: A novel mutation target of microsatellite instability
-
Ejima Y, Yang L, Sasaki MS. Aberrant splicing of the ATM gene associated with shortening of the intronic mononucleotide tract in human colon tumor cell lines: a novel mutation target of microsatellite instability. Int J Cancer 2000;86:262-8.
-
(2000)
Int J Cancer
, vol.86
, pp. 262-268
-
-
Ejima, Y.1
Yang, L.2
Sasaki, M.S.3
-
44
-
-
3142658762
-
Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin
-
Li H-R, Shagisultanova EI, Yamashita K, et al. Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin. Cancer Res 2004;64:4760-7.
-
(2004)
Cancer Res
, vol.64
, pp. 4760-4767
-
-
Li, H.-R.1
Shagisultanova, E.I.2
Yamashita, K.3
-
45
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, Cortez D, Yazdi P, et al. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000;14:927-39.
-
(2000)
Genes Dev
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
-
46
-
-
9744263911
-
The role of BRCA1 in the cellular response to chemotherapy
-
Kennedy RD, Quinn JE, Mullan PB, Johnston PG, Harkin DP. The role of BRCA1 in the cellular response to chemotherapy. J Natl Cancer Inst 2004;96:1659-68.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1659-1668
-
-
Kennedy, R.D.1
Quinn, J.E.2
Mullan, P.B.3
Johnston, P.G.4
Harkin, D.P.5
-
47
-
-
3242888037
-
Relevance and irrelevance of DNA damage response to radiotherapy
-
Connell PP, Kron SJ, Weichselbaum RR. Relevance and irrelevance of DNA damage response to radiotherapy. DNA Repair 2004;3:1245-51.
-
(2004)
DNA Repair
, vol.3
, pp. 1245-1251
-
-
Connell, P.P.1
Kron, S.J.2
Weichselbaum, R.R.3
|