Identification of a region of frequent loss of heterozygosity at 11q24 in colorectal cancer

Cancer Research

Volumn 59, Issue 12, 1999, Pages 2806-2809

  Connolly, Kate C ^a   Gabra, Hani ^a   Millwater, Christopher J ^b   Taylor, Karen J ^a   Rabiasz, Genevieve J ^a   Watson, J E Vivienne ^a   Smyth, John F ^a   Wyllie, Andrew H ^b   Jodrell, Duncan I ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 11Q; COLON CARCINOGENESIS; COLORECTAL CANCER; GENE LOCUS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; TELOMERE; TUMOR SUPPRESSOR GENE;

AGED; CHROMOSOMES, HUMAN, PAIR 11; COLORECTAL NEOPLASMS; DNA PRIMERS; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; MALE;

EID: 0033564102     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Fearon, E. R., and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61: 759-767, 1990.
2. Bodmer, W. F., Bailey, C. J., Bodmer, J., Bussey, H. J., Ellis, A., Gorman, P., Lucibello, F. C., Murday, V. A., Rider, S. H., and Scambler, P. Localisation of a gene for familial adenomatous polyposis on chromosome 5. Nature (Lond.), 328: 614-616, 1987.
3. Lane, D. P., and Crawford, L. V. T antigen is bound to host protein in SV40-transformed cells. Nature (Lond.), 278: 261-263, 1979.
4. Cunningham, C., Dunlop, M. G., Bird, C. C., and Wyllie, A. H. Deletion analysis of chromosome 8p in sporadic colorectal adenomas. Br. J. Cancer, 70: 18-20, 1994.
5. Fearon, E. R., Cho, K. R., Nigro, J. M., Kern, S. E., Simons, J. W., Ruppert, J. M., Hamilton, S. R., Preisinger, A. C., Thomas, G., Kinzler, K. W., and Vogelstein, B. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (Washington DC), 247: 49-56, 1990.
6. Mulleris, M., Salmon, R. J., and Dutrillaux, B. Cytogenetics of colorectal adenocarcinomas. Cytogenet. Cell Genet., 46: 143-156, 1990.
7. Konstantinova, L. N., Fleischman, E. W., Knisch, V. I., Perevozchikov, A. G., and Kopnin, B. P. Karyotype peculiarities of human colorectal adenocarcinomas. Hum. Genet., 86: 491-496, 1991.
8. Tanaka, K., Oshimura, M., Kikuchi, R., Seki, M., Hayashi, T., and Miyaki, M. Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18. Nature (Lond.), 349: 340-342, 1991.
9. Call, K. M., Glaser, T., Ito, C. Y., Buckler, A. J., Pelletier, J., Haber, D. A., Rose, E. A., Kral, A., Yeger, H., Lewis, W. H., Jones, C., and Housman, D. E. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell, 60: 509-520, 1990.
10. Dowdy, S. F., Fasching, C. L., Araujo, D., Lai, K. M., Livanos, E., Weissman, B. E., and Stanbridge, E. J. Suppression of tumorigenicity in Wilms tumor by the p15.5-p14 region of chromosome 11. Science (Washington DC), 254: 293-295, 1991.
11. Lee, M. H., Reynisdottir, I., and Massagué, J. Cloning of p57KIP2, a cyclin dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev., 9: 639-649, 1995.
12. Dong, J. T., Lamb, P. W., Rinkerschaeffer, C. W., Vukanovic, J., Ichikawa, T., Isaacs, J. T., and Barrett, J. C. Kail, a metastasis suppressor gene for prostate-cancer on human-chromosome 11p11.2. Science (Washington DC), 268: 884-886, 1995.
13. Keldysh, P. L., Dragani, T. A., Fleischman, E. W., Konstantinova, L. N., Perevoschikov, A. G., Pierotti, M. A., Della-Porta, G., and Kopnin, B. P. 11q deletions in human colorectal carcinomas: cytogenetics and restriction fragment length polymorphism analysis. Genes Chromosomes Cancer, 6: 45-50, 1993.
14. Gustafson, C. E., Young, J., Leggett, B., Searle, J., and Chenevix-Trench, G. Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours. Br. J. Cancer, 70: 395-397, 1994.
15. Gabra, H., Watson, J. E. V., Taylor, K. J., MacKay, J., Leonard, R. C. F., Steel, C. M., Porteous, D. J., and Smyth, J. F. Definition and refinement of a region of loss of heterozygosity at 11q23.3-q24.3 in epithelial ovarian cancer associated with poor prognosis. Cancer Res., 56: 950-954, 1996.
16. Davis, M., Hitchcock, A., Foulkes, W. D., and Campbell, I. G. Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer. Cancer Res., 56: 741-744, 1996.
17. Ashton-Rickardt, P. G., Dunlop, M. G., Nakamura, Y., Morris, R. G., Purdie, C. A., Steel, C. M., Evans, H. J., Bird, C. C., and Wyllie, A. H. High frequency of APC loss in sporadic colorectal carcinoma due to breaks clustered in 5q21-22. Oncogene, 4: 1169-1174, 1989.
18. James, M. R., Richard, C. W., III, Schott, J-J., Youstry, C., Clark, K., Bell, J., Terwilliger, J. D., Hazan, J., Dubay, C., Vignal, A., Agrapart, M., Imai, T., Nakamura, Y., Polymeropoulos, M., Weissenbach, J., Cox, D. R., and Lathrop, G. M. A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nat. Genet., 8: 70-76, 1994.
19. Hampton, G. M., Mannermaa, A., Winqvist, R., Alavaikko, M., Blanco, G., Taskinen, P. J., Kiviniemi, H., Newsham, I., Cavenee, W. K., and Evans, G. A. Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23.3. Cancer Res., 54: 4586-4589, 1994.
20. Launonen, V., Stenback, F., Puistola, U., Bloigu, R., Huusko, P., Kytola, S., Kauppila, A., and Winqvist, R. Chromosome 11q22.3-q25 LOH in ovarian cancer: associations with a more aggressive disease course and involved subregions. Gynecol. Oncol., 71: 299-304, 1998.
21. Koreth, J., Bakkenist, C. J., and McGee, J. O. Allelic deletions at chromosome 11q22-q23.1 and 11q25-qter are frequent in sporadic breast but not colorectal cancers. Oncogene, 14: 431-437, 1997.
22. Negrini, M., Rasio, D., Hampton, G. M., Sabbioni, S., Rattan, S., Carter, S. L., Rosenberg, A. L., Schwartz, G. F., Shiloh, Y., Cavenee, W. K., and Croce, C. M. Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: identification of a new region at 11q23.3. Cancer Res., 55: 3003-3007, 1995.
23. Hampton, G. M., Penny, L. A., Baergen, R. N., Larson, A., Brewer, C., Liao, S., Busby-Earle, R. M. C., Williams, A. W. R., Steel, C. M., Bird, C. C., Stanbridge, E. J., and Evans, G. A. Loss of heterozygosity in cervical carcinoma: subchromosomal localisation of a putative tumor-suppressor gene to chromosome 11q22-q24. Proc. Natl. Acad. Sci. USA, 91: 6953-6957, 1994.
24. Rasio, D., Negrini, M., Manenti, G., Dragani, T. A., and Croce, C. M. Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: identification of three independent regions. Cancer Res., 55: 3988-3991, 1995.
25. Hui, A. B. Y., Lo, K-W., Leung, S-F., Choi, P. H. K., Fong, Y., Lee, J. C. K., and Huang, D. P. Loss of heterozygosity on the long arm of chromosome 11 in nasopharyngeal carcinoma. Cancer Res., 56: 3225-3229, 1996.
26. Rasio, D., Negrini, M., and Croce, C. M. Genomic organisation of the ATM locus involved in ataxia-telangiectasia. Cancer Res., 55: 6053-6057, 1995.
27. Baysal, B. E., van Schothorst, E. M., Farr, J. E., James, E. R., Devilee, P., Richard, C. W., III. A high resolution STS, EST and gene-based physical map of the hereditary paraganglioma region on 11q23. Genomics, 44: 214-221, 1997.
28. Monaco, C., Negrini, M., Sozzi, G., Veronese, M. L., Vorechovsky, I., Godwin, A. K., and Croce, C. M. Molecular cloning and characterization of of LOH11CR2A, a new gene within a refined minimal region of LOH at 11q23. Genomics, 46: 217-222, 1997.
29. Sanchez, Y., Wong, C., Thoma, R. S., Wu, Z., Piwnica-Worms, H., and Elledge, S. J. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science (Washington DC), 277: 1497-1501, 1997.
30. Baffa, R., Negrini, M., Schichman, S. A., Huebner, K., and Croce, C. M. Involvement of the ALL-1 gene in a solid tumor. Proc. Natl. Acad. Sci. USA, 92: 4922-4926, 1995.