Immunohistochemical study on the prognostic value of MIB-1 in gastric carcinoma

British Journal of Cancer

Volumn 74, Issue 5, 1996, Pages 759-765

  Muller W ^a   Schneiders, A ^a   Meier, S ^a   Hommel, G ^b   Gabbert, H E ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Cell proliferation; Gastric cancer; Immunohistochemistry; Prognosis

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY KI 67; TUMOR ANTIGEN;

ARTICLE; BLOOD VESSEL; CANCER INVASION; CANCER SURVIVAL; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LYMPH NODE; LYMPH VESSEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; STOMACH CANCER; STOMACH CARCINOMA; SURVIVAL TIME; TUMOR DIFFERENTIATION;

EID: 0029766176     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.433     Document Type: Article

References (47)

1. AALTOMAA S, LIPPONEN P AND SYRJANEN K. (1993). Proliferating cell nuclear antigen (PCNA) immunolabeling as a prognostic factor in axillary lymph node negative breast cancer. Anticancer Res., 13, 533-538.
2. AL-SHENEBER IF, SHIBATA HR, SAMPALIS J AND JOTHY S. (1993). Prognostic significance of proliferating cell nuclear antigen expression in colorectal cancer. Cancer, 71, 1954-1959.
3. BRAVO R. (1986). Synthesis of the nuclear protein cyclin (PCNA) and its relationship with DNA replication. Exp. Cell Res., 163, 287-293.
4. BROWN DC AND GATTER KC. (1990). Monoclonal antibody Ki-67: its use in histopathology. Histopathology, 17, 489-503.
5. CATTORETTI G, BECKER MGH, KEY G, DUCHROW M, SCHLÜTER C, GALLE J AND GERDES J. (1992). Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J. Pathol., 168, 357 363.
6. CUMMINGS MC, FURNIVAL CM, PARSONS PG AND TOWNSEND E, (1993). PCNA immunostaining in breast cancer. Aust. N.Z. J. Surg., 63, 630-636.
7. FUJII M, MOTOI M, SAEKI H, AOE K AND MORIWAKI S. (1993). Prognostic significance of proliferating cell nuclear antigen (PCNA) expression in non-small cell lung cancer. Acta Med. Okayama, 47, 103 108.
8. GABBERT HE, WAGNER R AND HÖHN P. (1982). The relation between tumor cell proliferation and vascularization in differentiated and undifferentiated colon carcinomas in the rat. Virchows Arch. (Cell Pathol.), 41, 119-131.
9. GABBERT HE. (1985). Mechanisms in tumor invasion: evidence from in vivo observations. Cancer Metastasis Rev., 4, 293-309.
10. GABBERT HE, MEIER S, GERHARZ CD AND HOMMEL G. (1991). Incidence and prognostic significance of vascular invasion in 529 gastric cancer patients. Int. J. Cancer, 49, 203 207.
11. GASPARINI G, BEVILACQUA P, POZZA F, MELI S, BORACCHI P, MARUBINI E AND SAINSBURY JR. (1992a). Value of epidermal growth factor receptor status compared with growth fraction and other factors for prognosis in early breast cancer. Br. J. Cancer, 66, 970 976.
12. GASPARINI G, MELI S, POZZA F, CAZZAVILLAN S AND BEVILACQUA P. (1992b). Pc-10 antibody to proliferating cell nuclear antigen (PCNA) is not related to prognosis in human breast carcinoma. Growth Regul., 4, 145-150.
13. GERDES J, SCHWAB U, LEMKE H AND STEIN H. (1984). Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J. Immunol., 133, 1710-1715.
14. HAERSLEV T AND JACOBSEN GK. (1994). Proliferating cell nuclear antigen in breast carcinomas. An immunohistochemical study with correlation to histopathological features and prognostic factors. Virchows Arch., 424, 39-46.
15. HARPER ME, GLYNNE-JONES E, GODDARD L, WILSON DW, MATENHELIA SS, CONN IG, PEELING WB AND GRIFFITHS K. (1992). Relationship of proliferating cell nuclear antigen (PCNA) in prostatic carcinomas to various clinical parameters. Prostate, 20, 243-253.
16. HEMMING AW, DAVIS NL, KLUFTINGER A, ROBINSON B, QUENVILLE NF, LISEMAN B AND LERICHE J. (1992). Prognostic markers of colorectal cancer: an evaluation of DNA content, epidermal growth factor receptor, and Ki-67. J. Surg. Oncol., 51, 147 152.
17. HENRIKSEN R, STRANG P, BACKSTROM T, WILANDER E, TRIBUKAIT B AND OBERG K. (1994). Ki-67 immunostaining and DNA flow cytometry as prognostic factors in epithelial ovarian cancers. Anticancer Res., 14, 603-608.
18. HERMANEK P, AND SOBIN LH (EDS). (1987). TNM Classification of Malignant Tumours. pp. 43-46, Springer: Berlin.
19. ISOLA J, KALLIONIEMI OP, KORTE JM, WAHLSTROM T, AINE R, HELL M AND HELIN H. (1990). Steroid receptors and Ki-67 reactivity in ovarian cancer and in normal ovary: correlation with DNA (low cytometry, biochemical receptor assay, and patient survival. J. Pathol., 162, 295 301.
20. JAIN S, FILIPE MI, HALL PA, WASEEM N, LANE DP AND LEVISON DA. (1991). Prognostic value of proliferating cell nuclear antigen in gastric carcinoma. J. Clin. Pathol., 44, 655-659.
21. JORDAN PA, KERNS BJ, PENCE JC, KOHLER MF, BAST RC Jr. KINNEY RB AND BERCHUCK A. (1993). Determination of proliferation index in advanced ovarian cancer using quantitative image analysis. Am. J. Clin. Pathol., 99, 736-740.
22. KAKEJI Y, KORENAGA D, TSUJITANI S, HARAGUCHI M, MAEHARA Y AND SUGIMACHI K. (1991). Predictive value of Ki-67 and argyrophilic nucleolar organizer region staining for lymph node metastasis in gastric cancer. Cancer Res., 51, 3503-3506.
23. KALBFLEISCH JD AND PRENTICE RL. (1980). The Statistical Analysis of Failure Data. Wiley: New York.
24. KAPLAN EL AND MEIER P. (1958). Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc., 53, 457-481.
25. KERNS BM, JORDAN PA, FAERMAN LL, BERCHUCK A, BAST RC AND LAYFIELD LJ. (1994). Determination or proliferation index with MIB-1 in advanced ovarian cancer using quantitative image analysis. Am. J. Clin. Pathol., 101, 192-197.
26. KEY G, BECKER MHG, DUCHROW M, SCHLÜTER C AND GERDES J. (1992). New Ki-67 equivalent murine monoclonal antibodies (MIB 1-3) prepared against recombinant parts of the Ki-67 antigen. Anal. Cell. Pathol., 4, 181 188.
27. KUBOTA Y, PETRAS RE, EASLEY KA, BAUER TW, TUBBS RR AND FAZIO VW. (1992). Ki-67-determined growth fraction versus standard and grading parameters in colorectal carcinoma. Cancer, 70, 2602-2609.
28. LAUREN P. (1965). The two histological main types of gastric carcinomas: diffuse and so-called intestinal-type carcinoma. Acta Pathol. Microbiol. Immunol. Scand., 64, 31-49.
29. LIPPONEN PK AND ESKELINEN MJ. (1992). Cell proliferation of transitional cell bladder tumours determined by PCNA/cyclin immunostaining and its prognostic value. Br. J. Cancer, 66, 171-176.
30. MACDONALD-BRAVO H AND BRAVO R. (1985). Induction of the nuclear protein cyclin in serum-stimulated quiescent 3T3 cells is independent of DNA synthesis. Exp. Cell Res., 156, 455.
31. MAEDA K, CHUNG YS, TAKATSUKA S, OGAWA Y, ONODA N, SAWADA T, NITTA A, ARIMOTO Y, KONDO Y AND SOWA M. (1995). Tumour angiogenesis and tumour cell proliferation as prognostic indicators in gastric carcinoma. Br. J. Cancer, 72, 319-323.
32. MAYER A, TAKIMOTO M, FRITZ E, SCHELLANDER G, KOFLER K AND LUDWIG H. (1993). The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer. Cancer, 71, 2454-2460.
33. MORI M, KAKEJI Y, ADACHI Y, MORIGUCHI S, MAEHARA Y, SUGIMACHI K, JESSUP JM, CHEN LB AND STEELE GD Jr. (1993). The prognostic significance of proliferating cell nuclear antigen in clinical gastric cancer. Surgery, 113, 683-690.
34. MULDER AH, VAN HOOTEGEM JC, SYLVESTER R, TEN KATE FJ, KURTH KH, OOMS EC AND VAN DER KWAST TH. (1992). Prognostic factors in bladder carcinoma: histologic parameters and expression of a cell cycle-related nuclear antigen (Ki-67). J. Pathol., 166, 37-43.
35. OOTA K AND SOBIN LH. (1977). Histological Typing of Gastric and Oesophageal Tumours. International Histological Classification of Tumours. WHO, Geneva. Springer: Berlin.
36. QUINN CM AND WRIGHT NA. (1990). The clinical assessment of proliferation and growth in human tumours: evaluation of methods and applications as prognostic variables. J. Pathol., 160, 93-102.
37. PORSCHEN R, KRIEGEL A, LANGEN C, CLASSEN S, HILSE M, LOHE B, HENGELS KJ AND BORCHARD F. (1991). Assessment of proliferative activity in carcinomas of the human alimentary tract by Ki-67 immunostaining. Int. J. Cancer, 47, 686-691.
38. RAILO M, NORDLING S, VON BOGUSLAWSKY K, LEIVONEN M, KYLLONEN L AND VON SMITTEN K. (1993). Prognostic value of Ki-67 immunolabelling in primary operable breast cancer. Br. J. Cancer, 68, 579-583.
39. SIITONEN SM, KALLIONIEMI OP AND ISOLA JJ. (1993). Proliferating cell nuclear antigen immunohistochemistry using monoclonal antibody 19A2 and a new antigen retrieval technique has prognostic impact in archival paraffin-embedded node-negative breast cancer. Am. J. Pathol., 142, 1081-1089.
40. SKOPELITOU A, KORKOLOPOULOU P, PAPANICOLAOU A, CHRISTODOULOU P, THOMAS-TSAGLI E AND PAVLAKIS K. (1992). Comparative assessment of proliferating cell nuclear antigen immunostaining and of nucleolar organizer region staining in transitional cell carcinomas of the urinary bladder. Correlation with other conventional prognostic pathologic parameters. Eur. Urol., 22, 235-240.
41. THOMAS H, NASIM MM, SARRAF CE, ALISON MR, LOVE S, LAMBERT HE AND PRICE P. (1995). Proliferating cell nuclear antigen (PCNA) immunostaining - a prognostic factor in ovarian cancer? Br. J. Cancer, 71, 357-362.
42. THOMAS M, NOGUCHI M, KITAGAWA H, KINOSHITA K AND MIYAZAKI I. (1993). Poor prognostic value of proliferating cell nuclear antigen labelling index in breast carcinoma. J. Clin. Pathol., 46, 525-528.
43. TUBIANA M, PEJOVIC MH, KOSCIELNY S, CHVAUDRA N AND MALAISE E. (1989). Growth rate, kinetics of tumor cell proliferation and long-term outcome in human breast cancer. Int. J. Cancer, 44, 17-22.
44. YONEMURA Y, OHOYAMA S, KIMURA H, KAMATA T, YAMAGUCHI A AND MIYAZAKI I. (1990a). Assessment of tumor cell kinetics by monoclonal antibody Ki-67. Eur. Surg. Res., 22, 365-370.
45. YONEMURA Y, OHOYAMA S, SUGIYAMA K, NINOMIYA I, KAMATA T, YAMAGUCHI A, MATSUMOTO H AND MIYAZAKI I. (1990b) Growth fractions in gastric carcinomas determined with monoclonal antibody Ki-67. Cancer, 65, 1130-1134.
46. YONEMURA Y, OHOYAMA S, KIMURA T, MATSUMOTO H, YAMAGUCHI A, KOSAKA T, MIWA K AND MIYAZAKI I. (1991). The expression of proliferative-associated nuclear antigen p105 in gastric carcinoma. Cancer, 67, 2523-2528.
47. YONEMURA Y, KIMURA H, FUSHIDA S, TUGAWA K, NAKAI Y, KAJI M, FONSECA L, YAMAGUCHI A AND MIYAZAKI I. (1993). Analysis of proliferative activity using anti-proliferating cell nuclear antigen antibody in gastric cancer tissue specimens obtained by endoscopic biopsy. Cancer, 71, 2448-2453.