The Role of Dairy Foods in Weight Management

Journal of the American College of Nutrition

Volumn 24, Issue , 2005, Pages 537S-546S

  Zemel, Michael B ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

ACE inhibition; Adipocyte; Branched chain amino acids; Calcium; Dairy; Obesity; Whey

Indexed keywords

AMINO ACID; CALCITRIOL; CALCIUM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; TRIACYLGLYCEROL;

BODY FAT; CALCIUM INTAKE; CALCIUM TRANSPORT; CALORIC RESTRICTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DAIRY PRODUCT; ENERGY METABOLISM; FOOD INTAKE; GENE EXPRESSION; HUMAN; LIPID METABOLISM; LIPID OXIDATION; LIPOGENESIS; NONHUMAN; OBESITY; OBSERVATIONAL STUDY; RANDOMIZED CONTROLLED TRIAL; REVIEW; RISK FACTOR; VITAMIN SUPPLEMENTATION; WEIGHT CONTROL; ADIPOSE TISSUE; ANIMAL; BODY WEIGHT; DRUG EFFECT; METABOLISM; PHYSIOLOGY; WEIGHT REDUCTION;

MUS;

ADIPOSE TISSUE; ANIMALS; BODY WEIGHT; CALCITRIOL; CALCIUM; CALCIUM, DIETARY; DAIRY PRODUCTS; ENERGY METABOLISM; HUMANS; LIPID METABOLISM; OBESITY; WEIGHT LOSS;

EID: 33644834318     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.2005.10719502     Document Type: Article

References (87)

1. Jones BH, Kim JH, Zemel MB, Woychik RP, Michaud EJ, Wilkison WO, Moustaid N: Upregulation of adipocyte metabolism by agouti protein: Possible paracrine actions in yellow mouse obesity. Am J Physiol 20: E192-E196, 1996.
2. Zemel MB, Kim JH, Woychik RP, Michaud EJ, Kadwell SH, Patel IR, Wilkison WO: Agouti regulation of intracellular calcium: Role in the insulin resistance of viable yellow mice. Proc Nat Acad Sci USA 92: 4733-4737, 1995.
3. Xue B, Moustaid-Moussa N, Wilkison WO, Zemel MB: The agouti gene product inhibits lipolysis in human adipocytes via a Ca2 dependent mechanism. FASEB J 12: 1391-1396, 1998.
4. Xue B, Greenberg AG, Kraemer FB, Zemel MB: Mechanism of intracellular calcium inhibition of lipolysis in human adipocytes. FASEB J 15: 2527-2529, 2001.
5. Kim JH, Mynatt RL, Moore JW, Woychik RP, Moustaid N, Wilkison WO, Zemel MB: The effects of calcium channel blockade on agouti-induced obesity. FASEB J 10: 1646-1652, 1996.
6. Claycombe KH, Wang Y, Jones BH, Kim S, Wilkison WO, Zemel MB, Chun J, Moustaid-Moussa N: Transcriptional regulation of the adipocyte fatty acid synthase gene by the agouti gene product: Interaction with insulin. Physiological Genomics 3: 157-162, 2000.
7. Shi H, Moustaid-Moussa N, Wilkison WO, Zemel MB: Role of the sulfonylurea receptor in regulating human adipocyte metabolism. FASEB J 13: 1833-1838, 1999.
8. Xue B, Zemel MB: Relationship between human adipose tissue agouti and fatty acid synthase (FAS). J Nutr 130: 2478-2481, 2000.
9. Voisey J, Imbeault P, Hutley L, Prins JB, van Daal A: Body mass index-related human adipocyte agouti expression is sex-specific but not depot-specific. Obes Res 10: 447-452, 2002.
10. Zemel MB, Xue B: Agouti/melanocortin interactions with leptin pathways in obesity. Nutr Rev 1998; 56: 271-274, 1998.
11. Tebar F, Soley M, Ramirez I: The antilipoytic effects of insulin and epidermal growth factor in rat adipocytes are mediated by different mechanisms. Endocrinology 137: 4181-4188, 1996.
12. Xue B, Wilkison WO, Mynatt RL, Moustaid N, Goldman M, Zemel MB: The agouti gene product stimulates pancreatic cell signaling and insulin release. Physiol Genomics 1: 11-19, 1999.
13. Mynatt RL, Miltenberger RJ, Klebig ML, Zemel MB, Wilkinson JE, Wilkison WO, Woychik RP: Combined effects of insulin treatment and adipose tissue-specific agouti expression on the development of obesity. Proc Natl Acad Sci USA 94, 919-922, 1997.
14. Mynatt RL, Truett GE: Influence of agouti protein on gene expression in mouse adipose tissue [Abstract]. FASEB J 14: A733, 2000.
15. Zemel MB, Mynatt RL, Dibling D: Synergism between dietinduced hyperinsulinemia and adipocyte-specific agouti expression [Abstract]. FASEB J 13: 660.3, 1999.
16. Kwon HY, Bultman SJ, Loffler C, Chen W, Furdon PJ, Powell JG, Usala AL, Wilkison W, Hansmann I, Woychik RP: Molecular structure and chromosomal mapping of the human homolog of the agouti gene. Proc Natl Acad Sci USA 91: 9760-9764, 1994.
17. Kim JH, Mynatt RL, Moore JW, Woychik RP, Moustaid N, Wilkison WO, Zemel MB: The effects of calcium channel blockade on agouti-induced obesity. FASEB J 10: 1646-1652, 1996.
18. Standridge M, Alemzadeh R, Zemel M, Koontz J, Moustaid-Moussa N: Diazoxide down-regulates leptin and lipid metabolizing enzymes in adipose tissue of Zucker rats. FASEB J 14: 455-460, 2000.
19. Alemzadeh R, Slonim AE, Zdanowicz MM, Maturo J: Modification of insulin resistance by diazoxide in obese Zucker rats. Endocrinology 133: 705-712, 1993.
20. Alemzadeh R, Jacobs AW, Pitukcheewnont P: Antiobesity effect of diazoxide in obese Zucker rats. Metabolism 45: 334-341, 1996.
21. Alemzadeh R, Langley G, Upchurch L, Smith P, Slonim AE: Beneficial effect of diazoxide in obese hyperinsulinemic adults. J Clin Endocr Metab 1998; 83: 1911-1915.
22. Zemel MB, Shi H, Greer B, DiRienzo D, Zemel PC: Regulation of adiposity by dietary calcium. FASEB J 14: 1132-1138, 2000.
23. Shi H, Norman AW, Okamura WH, Sen A, Zemel MB: 1, 25-dihyroxyvitamin D3 modulates human adipocyte metabolism via non-genomic action. FASEB J 14: 2751-2753, 2001.
24. Zemel MB: Role of calcium and dairy products in energy partitioning and weight management. Am J Clin Nutr 79: 907S-912S, 2004.
25. Shi H, DiRienzo D, Zemel MB: Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energyrestricted aP2-agouti transgenic mice. FASEB J 15: 291-293, 2001.
26. Ye WZ, Reis AF, Dubois-Laforgue D, Bellanne-Chantelot C, Timsit J, Velho G: Vitamin D receptor gene polymorphisms are associated with obesity in type 2 diabetic subjects with early age of onset. Eur J Endocrinol 145: 181-186, 2001.
27. Barger-Lux MJ, Heaney RP, Hayes HF, DeLuca HF, Johnson ML, Gong G: Vitamin D receptor gene polymorphism, bone mass, body size, and vitamin D receptor density. Calcif Tissue Int 57: 161-162, 1995.
28. Andersen T, McNair P, Hyldstrup L, Fogh AN, Nielsen TT, Astrup A, Transbol I: Secondary hyperparathyroidism of morbid obesity regresses during weight reduction. Metabolism 37: 425-428, 1988.
29. Bell NH, Epstein S, Greene A, Shary J, Oexmann MJ, Shaw S: Evidence for alteration of the vitamin D-endocrine system in obese subjects. J Clin Invest 76: 370-373, 1985.
30. Nemere I, Safford SE, Rohe B, DeSouza MM, Farach-Carson MC: Identification and characterization of 1,25-(OH)2-D3 membraneassociated rapid response, steroid (1,25D3-MARRS) binding protein. J Steroid Biochem Mol Biol 89-90: 281-285, 2004.
31. Nemere I, Farach-Carson MC, Rohe B, Sterling TM, Norman AW, Boyan BD, Safford SE: Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells. Proc Nat Acad Sci USA 101: 7392-7397, 2004.
32. Shi H, Norman AW, Okamura WH, Sen A, Zemel MB: 1,25-dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes. FASEB J 16: 1808-1810, 2002.
33. Sun X, Zemel MB: Mechanisms of dual effects of 1, 25-dihydroxyvitamin D3 on adipocyte apoptosis. FASEB J 18: 1430-1432, 2004.
34. Papakonstantinou E, Flatt WP, Huth PJ, Harris RBS: High dietary calcium reduces body fat content, digestibility of fat, and serum vitamin D in rats. Obesity Res 11: 387-394, 2003.
35. Jacobsen R, Lorenzen JK, Toubro S, Krog-Mikkelsen K, Astrup A: Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. Int J Obesity 29: 292-301, 2005.
36. Denke MA, Fox MM, Schulte MC: Short-term dietary calcium fortification increases fecal saturated fat content and reduces serum lipids in men. J Nutr 123: 1047-1053, 1993.
37. Welberg JW, Monkelbaan JF, de Vries EG, Muskiet FA, Cats A, Oremus ET, Boersma-van Ek W, van Rijsbergen H, van der Meer R, Mulder NH, et al: Effects of supplemental dietary calcium on quantitative and qualitative fecal fat excretion in man. Ann Nutr Metabo 38: 185-191, 1994.
38. Shahkhalili Y, Murset C, Meirim I, Duruz E, Guinchard S, Caradini C, Acheson K: Calcium supplementation of chocolate: Effect on cocoa butter digestibility and blood lipids in humans. Am J Clin Nutr 73: 246-252, 2001.
39. Causey KR, Zemel MB: Dairy augmentation of the anti-obesity effect of Ca in aP2-agouti transgenic mice [Abstract]. FASEB J A746, 2003.
40. Zemel MB: Role of dietary calcium and dairy products in modulating adiposity. Lipids 2003;38: 139-146.
41. Bos C, Gaudichon C, Tome D: Nutritional and physiological criteria in the assessment of milk protein quality for humans. J Am Coll Nutr 19: 191S-205S, 2000.
42. Layman DK: The role of leucine in weight loss diets and glucose homeostasis. J Nutr 133: 261S-267S, 2003.
43. Anthony JC, Anthony TG, Kimball SR, Jefferson LS: Signaling pathways involved in translational control of protein synthesis in skeletal muscle by protein. J Nutr 131: 856S-860S, 2000.
44. Garlick PJ, Grant I: Amino acid infusion increases the sensitivity of muscle protein synthesis in vivo to insulin. Biochem J 254: 579-584, 1988.
45. Ha E, Zemel MB: Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people. J Nutr Biochem 14: 251-258, 2003.
46. Fouillet H, Mariotti F, Gaudichon C, Bos C, Tome D: Peripheral and splanchnic metabolism of dietary nitrogen are differently affected by the protein source in humans as assessed by compartmental modeling. J Nutr 132: 125-133, 2002.
47. Zemel MB, Thompson W, Milstead A, Morris K, Campbell P: Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res 12: 582-590, 2004.
48. Zemel MB, Richards J, Mathis S, Milstead A, Gebhardt L, Silva E: Dairy augmentation of total and central fat loss in obese subjects. Int J Obesity 29: 391-397, 2005.
49. Zemel MB, Milstead A, Richards J, Campbell P: Effects of calcium and dairy on body composition and weight loss in African American adults. Obes Res 13: 1218-1225, 2005.
50. Zemel MB, Teegarden D, Van Loan M, Schoeller DA, Matkovic V, Lyle M, Craig BA: Role of dairy products in modulating weight and fat loss: A multi-center trial [Abstract]. FASEB J 18: 566.5, 2004.
51. Seckl JR, Walker BR: 11-hydroxysteroid dehydrogenase Type 1-a tissue-specific amplifier of glucocorticoid action. Endocrinology 142: 1371-1376, 2001.
52. Rask E, Olsson T, Soderberg S, Andrew R, Livingstone DE, Johnson O, Walker BR: Tissue-specific dysregulation of cortisol metabolism in human obesity. J Clin Endocrinol Metabol 86: 1418-1421, 2001.
53. Masuzaki H, Paterson J, Shinyama H, Morton NM, Mullins JJ, Seckl JR, Flier JS: A transgenic model of visceral obesity and the metabolic syndrome. Science 294: 2166-2170, 2001.
54. Masuzaki H, Yamamoto H, Kenyon CJ, Elmquist JK, Morton NM, Paterson JM, Shinyama H, Shart MGF, Fleming S, Mullins JJ, Seckl JR, Flier JS: Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. J Clin Invest 112: 83-90, 2003.
55. Kotelevstev Y, Holmes MC, Burchell A, Houston PM, Schmoll D, Jamieson P, Best R, Brown R, Edwards CR, Seckl JR, Mullins JJ: 11-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia in obesity or stress. Proc Natl Acad Sci USA 94: 14924-14929, 1997.
56. Morris KL, Zemel MB: 1,25-dihydroxyvitamin D3 modulation of adipocyte glucocorticoid function. Obesity Res 2005 (in press).
57. Zemel MB, Sun X, Geng X: Effects of a calcium-fortified breakfast cereal on adiposity in a transgenic mouse model of obesity [Abstract]. FASEB J: A598, 480.7, 2001.
58. Zemel MB, Geng X: Dietary calcium and yogurt accelerate body fat loss secondary to caloric restriction in aP2-agouti transgenic mice. Obesity Res 9: 146S, 2001.
59. Zemel MB, Morgan K: Interaction between calcium, dairy and dietary macronutrients in modulating body composition in obese mice. FASEB J 16: A369, 2002.
60. Causey KR, Zemel MB: Dairy augmentation of the anti-obesity effect of Ca in aP2-agouti transgenic mice. FASEB J A746: 453.7, 2003.
61. Zhang Q, Tordoff MG: No effect of dietary calcium on body weight of lean and obese mice and rats. Am J Physiol R669-677, 2004.
62. Bursey RD, Sharkey T, Miller GD: High calcium intake lowers weight in lean and fatty Zucker rats. FASEB J 3: A265, 1989.
63. Metz JA, Karanja N, Torok J, McCarron DA: Modification of total body fat in Spontaneously Hypertensive rats and Wistar-Kyoto rats. Am J Hypertension 1: 58-60, 1988.
64. Sun X, Zemel MB: Calcium and dairy products inhibit weight and fat regaind during ad libitum consumption following energy restriction in aP2-agouti transgenic mice. J Nutr 3054-3060, 2004.
65. Davies KM, Heaney RP, Recker RR, Lappe JM, Barger-Lux MJ, Rafferty K, Hinders S: Calcium intake and body weight. J Clin Endocrinol Metab 85: 4635-4638, 2000.
66. Heaney RP, Davies KM, Bargar-Lux MJ: Calcium and weight: Clinical studies. J Am Coll Nutr 21: 152S-155S, 2002.
67. Heaney RP: Normalizing calcium intake: Projected population effects for body weight. J Nutr 133: 268S-270S, 2003.
68. Bowen J, Noakes M, Clifton PM: Effect of calcium and dairy foods in high protein, energy-restricted diets on weight loss and metabolic parameters in overweight adults. In J Obesity advance online publication; doi: 10,1038.sj.ijo.802895, 2005.
69. Zemel MB: Role of dairy products in the prevention of weight regain following weight loss [Abstract]. FASEB J 19, 2005.
70. Melanson EL, Shart TA, Schneider J, Donahoo WT, Grunwald GK, Hill JO: Relation between calcium intake and fat oxidation in adult humans. Int J Obesity 27: 196-203, 2003.
71. Melanson EL, Donahoo WT, Dang F, Ida T, Zemel MB: Effect of low-and high-calcium dairy based diets on macronutrient oxidation in humans. Obes Res, in press, 2005.
72. Carruth BR, Skinner JD: The role of dietary calcium and other nutrients in moderating body fat in preschool children. Int J Obesity 25: 559-566, 2001.
73. Skinner JD, Bounds W, Carruth BR, Ziegler P: Longitudinal calcium intake is negatively related to children's body fat indexes. JADA 103: 1626-1631, 2003.
74. Barba G, Troiano E, Russo P, Venezia A, Siani A: Inverse association between body mass and frequency of milk consumption in children. Brit J Nutr 93: 15-19, 2005.
75. Tanasescu M, Ferris AM, Himmelgreen DA, Rodriguez N, Perez-Escamilla R: Biobehavioral factors are associated with obesity in Puerto Rican children. J Nutr 130: 1734-1742, 2000.
76. Novotny R, Daida YG, Acharya S, Grove JS, Vogt TM: Dairy intake is associated with lower body fat and soda intake with greater weight in adolescent girls. J Nutr 134: 1905-1909, 2004.
77. Lin Y-C, Lyle RM, McCabe LB, McCabe GB, Weaver CM, Teegarden D: Dairy calcium is related to changes in body composition during a two-year exercise intervention in young women. J Am Coll Nutr 19: 754-760, 2000.
78. Buchowski MS, Semenya J, Johnson AO: Dietary calcium intake in lactose maldigesting intolerant and tolerant African-American women. J Am Coll Nutr 21: 47-54, 2002.
79. McCarron DA: Calcium and magnesium nutrition in human hypertension. Ann Intern Med 98: 800-805, 1983.
80. Albertson AM, Good CK, Holschuh NM, Eldridge EL: The relationship between dietary calcium intake and body mass index in adult women from three National dietary intake databases [Abstract]. FASEB J 18: 6259, 2004.
81. Loos R, Rankinen T, Leon A, Skinner JS, Wilmore JH, Rao DC, Bouchard C: Calcium intake is associated with adiposity in black and white men and white women of the HERITAGE family study. J Nutr 134: 1772-1778, 2004.
82. Jaqmain M, Doucet E, Despres J-P, Bouchard C, Tremblay A: Calcium intake, body composition, and lipoprotein-lipid concentrations in adults. Am J Clin Nutr 77: 1448-1452, 2003.
83. Pereira MA, Jacobs DR, Van Horn L, Slattery ML, Kartashov AI, Ludwig DS: Dairy consumption, obesity, and the insulin resistance syndrome in young adults. The CARDIA study. JAMA 287: 2081-2089, 2002.
84. Mirmiran P, Esmaillzadeh A, Azizi F: Dairy consumption and body mass index. An inverse relationship. Int J Obesity 29: 115-121, 2005.
85. Phillips SM, Bandini LG, Cyr H, Colclough-Douglas S, Naumova E, Must A: Dairy food consumption and body weight and fatness studied longitudinally over the adolescent period. Int J Obesity 27: 1106-1113, 2003.
86. Moore LL, Singer MR, Bradlee ML, Ellison RC: Dietary predictors of excess body fat acquisition during childhood [Abstract]. Presented at 44th American Heart Association Annual Conference on Cardiovascular Disease Epidemiology and Prevention, 2004.
87. Berkey CS, Helain RS, Willett WC, Colditz GA: Milk, dairy fat, dietary calcium and weight gain" A longitudinal study of adolescents. Arch Pediatr Adolesc Med 159: 543-550, 2005.