The antilipolytic effects of insulin and epidermal growth factor in rat adipocytes are mediated by different mechanisms

Endocrinology

Volumn 137, Issue 10, 1996, Pages 4181-4188

  Tebar, Francesc ^a   Soley, Maria ^a   Ramírez, Ignasi ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; EPIDERMAL GROWTH FACTOR; PROTEIN KINASE C INHIBITOR; SOMATOMEDIN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL PROLIFERATION; ENZYME ACTIVITY; HORMONAL REGULATION; HORMONE ACTION; INSULIN RELEASE; LIPOGENESIS; LIPOLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY;

EID: 0029768831     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.10.8828475     Document Type: Article

References (55)

1. Serrero G 1987 EGF inhibits the differentiation of adipocyte precursors in primary cultures. Biochem Biophys Res Commun 146:194-202
2. Serrero G, Mills D 1991 Physiological role of epidermal growth factor on adipose tissue development in vivo. Proc Natl Acad Sci USA 88:3912-3916
3. Haystead TAJ, Hardie DG 1986 Both insulin and epidermal growth factor stimulate lipogenesis and acetyl-CoA carboxylase activity in isolated adipocytes. Importance of homogeneization procedure in avoiding artefacts in acetyl-CoA carboxylase assay. Biochem J 234:279-284
4. Tebar F, Ramírez I, Soley M 1993 Epidermal growth factor modulates the lipolytic action of catecholamines in rat adipocytes. Involvement of a Gi protein. J Biol Chem 268:17199-17204
5. Kurachi H, Adachi H, Ohtsuka S, Morishige K, Amemiya K, Keno Y, Shimomura I, Tokunaga K, Miyake A, Matsuzawa Y, Tanizawa O 1993 Involvement of epidermal growth factor in inducing obesity in ovariectomized mice. Am J Physiol 265:E323-E331
6. Adachi H, Kurachi H, Homma H, Adachi K, Imai T, Morishige K-I, Matsuzawa Y, Miyake A 1994 Epidermal growth factor promotes adipogenesis of 3T3-L1 cell in vitro. Endocrinology 135:1824-1830
7. Cohen S, Carpenter G, King Jr L 1980 Epidermal growth factor-receptor-kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. J Biol Chem 255:4834-4842
8. Kasuga M, Karlsson FA, Kahn CR 1982 Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor. Science 215:185-187
9. Kasuga M, Zick Y, Blithe DL, Crettaz M, Kahn CR 1982 Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system. Nature 298:667-669
10. White MF, Maron R, Kahn CR 1985 Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells. Nature 318:183-186
11. Pawson T 1995 Protein modules and signalling networks. Nature 373:573-580
12. Fantl WJ, Johnson DE, Williams LT 1993 Signalling by receptor tyrosine kinases. Annu Rev Biochem 62:453-481
13. Malarkey K, Belham CM, Paul A, Graham A, McLees A, Scott PH, Plevin R 1995 The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors. Biochem J 309:361-375
14. Manganiello VC, Degerman E, Smith CJ, Vasta V, Tomqvist H, Belfrage P 1992 Mechanisms for activation of the rat adipocyte particulate cyclic-GMP-inhibited cyclic AMP phosphodiesterase and its importance in the antilipolytic action of insulin. In: Strada SJ, Hidaka H (eds) Advances in Second Messenger and Phosphoprotein Research. Raven Press, New York, vol 25:147-164
15. Belfrage P, Fredrickson G, Stralfors P, Tornqvist H 1984 Adipose tissue lipases. In: Borgström B, Brockman HL (eds) Lipases. Elsevier, Amsterdam, pp 365-416
16. Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M 1994 Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. J Biol Chem 269:3568-3573
17. Rahn T, Ridderstråle M, Tornqvist H, Manganiello V, Fredrikson G, Belfrage P, Degerman E 1994 Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes: studies using the selective inhibitor wortmannin. FEBS Lett 350:314-318
18. Miller ES, Ascoli M 1990 Anti-phosphotyrosine immunoprecipitation of phosphatidylinositol-3′ kinase activity in different cell types after exposure to epidermal growth factor. Biochem Biophys Res Commun 173:289-295
19. Zorzano A, Soley M, Herrera E 1989 Rapid effect of insulin and glucose on the hepatic incorporation of gluconeogenic substrates into glyceride glycerol and glycogen. Int J Biochem 21:1071-1075
20. Wieland OH 1984 Glycerol: UV-method. In: Bergmeyer HV, Bergmeyer J, Grabl M (eds) Methods in Enzymatic Analysis. Verlag Chemie, Weinheim, pp 504-510
21. Burgaya F, Peinado J, Vilaró S, Llobera M, Ramírez I 1989 Lipoprotein lipase activity in neonatal-rat liver cell types. Biochem J 259:159-166
22. Peinado-Onsurbe J, Soler C, Soley M, Llobera M, Ramírez I 1992 Lipoprotein lipase and hepatic lipase activities are differentially regulated in isolated hepatocytes from neonatal rats. Biochim Biophys Acta 1125:82-89
23. Ramírez I, Kryski AJ, Ben-Zeev O, Schotz MC, Severson DL 1985 Characterization of triacylglycerol hydrolase activities in isolated myocardial cells from rat heart. Biochem J 232:229-236
24. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
25. Quintana I, Grau M, Moreno F, Soler C, Ramírez I, Soley M 1995 The early stimulation of glycolysis by epidermal growth factor in isolated rat hepatocytes is secondary to the glycogenolytic effect. Biochem J 308:889-894
26. Kullback S, Keegel JC 1991 Categorical data problems using information theoretic approch. In: Krisbnaiah PR, San PK (eds) Handbook of Statistics. North-Holland, Amsterdam, vol 4:831-871
27. Robinson DS 1970 The function of triglycerides in fatty acid transport. Compr Biochem 18:51-116
28. Eckel RH 1987 Adipose tissue lipoprotein lipase. In: Borensztajn J (ed) Lipoprotein Lipase. Evener, Chicago, pp 79-132
29. Chan BL, Lisanti MP, Rodriguez-Boulan E, Saltiel AR 1988 Insulin-stimulated release of lipoprotein lipase by metabolism of its phosphatidylinositol anchor. Science 241:1670-1672
30. Standaert ML, Bandyopadhyay G, Farese RV 1995 Studies with wortmannin suggest a role for phosphatidylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: comparison of insulin and protein kinase C modulators. Biochem Biophys Res Commun 209:1082-1088
31. Ui M, Okada T, Hazeki K, Hazeki O 1995 Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 20:303-307
32. Kelly KL, Deeney JT, Corkey BE 1989 Cytosolic free calcium in adipocytes. Distinct mechanisms of regulation and effects on insulin action. J Biol Chem 264:12754-12757
33. Blackmore PF, Augert G 1989 Effect of hormones on cytosolic free calcium in adipocytes. Cell Calcium 10:561-567
34. Draznin B, Sussman K, Kao M, Lewis D, Sherman N 1987 The existence of an optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes. J Biol Chem 262:14385-14388
35. Honnor RC, Dhillon GS, Londos C 1985 cAMP-dependent protein kinase and lipolysis in rat adipocytes. II. Definition of steady-state relationship with lipolytic and antilipolytic modulators. J Biol Chem 260:15130-15138
36. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charon D, Kirilovsky J 1991 The bisindoylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 266:15771-15781
37. Degerman E, Smith CJ, Tornqvist H, Vasta V, Belfrage P, Manganiello VC 1990 Evidence that insulin and isoprenaline activate cGMP inhibited low Km cAMP phosphodiesterase in rat fat cells by phosphorylation. Proc Natl Acad Sci USA 874:533-537
38. Eriksson H, Ridderstråle M, Degerman E, Ekholm D, Smith CJ, Manganiello VC, Belfrage P, Tornqvist H 1995 Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin. Biochim Biophys Acta 1266:101-107
39. 2 activity in Swiss 3T3 cells - wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. J Biol Chem 270:25352-25355
40. Carpenter G 1992 Receptor tyrosine kinase substrates - src homology domains and signal transduction. FASEB J 6:3283-3289
41. Pandiella A, Beguinot L, Velu TJ, Meldolesi J 1988 Transmembrane signalling at epidermal growth factors overexpressed in NIH 3T3 cells. Phosphoinositide hydrolysis, cytosolic Ca2+ increase and alkalinization correlate with epidermal-growth-factor-induced proliferation. Biochem J 254:223-228
42. Rofe AM, Williamson DH 1983 Metabolic effects of vasopressin infusion in the starved rat. Reversal of ketonaemia. Biochem J 212:231-239
43. Rofe AM, Williamson DH 1983 Mechanism for the 'anti-lipolytic' action of vasopressin in the starved rat. Biochem J 212:899-902
44. Susa M, Olivier AR, Fabbro D, Thomas G 1989 EGF induces biphasic 86 kinase activation: late phase is protein kinase C-dependent and conrtibutes to mitogenicity. Cell 57:817-824
45. Susa M, Vulevic D, Lane HA, Thomas G 1992 Inhibition or down-regulation of protein kinase-C attenuates late phase p70(s6k) activation induced by epidermal growth factor but not by platelet-derived growth factor or insulin. J Biol Chem 267:6905-6909
46. Yeo E-J, Exton JH 1995 Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells. J Biol Chem 270:3980-3988
47. Franklin CC, Kraft AS 1992 Protein kinase-C-independent activation of c-jun and c-fos transcription by epidermal growth factor. Biochim Biophys Acta 1134:137-142
48. Boniece IR, Wagner JA 1993 Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis. J Neurosci 13:4220-4228
49. Nishizuka Y 1988 The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334:661-665
50. Nishizuka Y 1995 Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9:484-496
51. Martiny-Baron G, Kananietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, Marmé D, Schächtele C 1993 Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J Biol Chem 268:9194-9197
52. Houslay MD 1991 'Crosstalk': a pivotal role for protein kinase C in modulating relationships between signal transduction pathways. Eur J Biochem 195:9-27
53. Naghshineh S, Noguchi M, Huang K-P, Londos C 1986 Activation of adipocyte adenylate cyclase by protein kinase C. J Biol Chem 261:14534-14538
54. i. FEBS Lett 243:77-82
55. Chambaut-Guerin A-M, Thomopoulos P 1987 Protein kinase C potentiates isoproterenol-mediated cycli AMP production without modifying the homologous desensitization process in J774 cells. Eur J Biochem 170:381-387