Role of the sulfonylurea receptor in regulating human adipocyte metabolism

FASEB Journal

Volumn 13, Issue 13, 1999, Pages 1833-1838

  Shi, Hang ^a   Moustaid Moussa, Naima ^a   Wilkison, W O ^b   Zemel, Michael B ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b Zen Bio Inc   (United States)

Author keywords

Adipocytes; Fatty acid synthase; Intracellular Ca2+; SUR

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; DIAZOXIDE; FATTY ACID SYNTHASE; GLIBENCLAMIDE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; INSULIN; POTASSIUM; POTASSIUM CHANNEL; SULFONYLUREA RECEPTOR; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; INSULIN RELEASE; LIPID METABOLISM; LIPOGENESIS; LIPOLYSIS; NORTHERN BLOTTING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WEIGHT GAIN;

ANIMALIA;

EID: 0032827036     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.13.13.1833     Document Type: Article

References (32)

1. Byyny, R. L., Loverde, M., Llotd, S., Mitchell, W., and Draznin, B. (1992) Cytosolic calcium and insulin resistance in elderly patients with essential hypertension. Am. J. Hypertension 5, 459-464
2. Draznin, B., Sussman, K. E., Eckel, R. H., Kao, M., Yost, T., and Sherman, N. A. (1988) Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia. J. Clin. Invest. 82, 1848-1852
3. Draznin, B., Sussman, K., Kao, K., Lewis, D., and Sherman, N. (1987) The existence of an optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes. J. Biol. Chem. 262, 14385-14388
4. Kim, J. H., Kiefer, L. L., Woychik, R. P., Wilkison, W. O., Truesdale, A., Ittoop, O., Willard, D., Nichols, J., and Zemel, M. B. (1997) Agouti regulation of intracellular calcium. Role of melanocortin receptor. Am. J. Physiol. 272, E379-E384
5. Zemel, M. B., Kim, J. H., Woychik, R. P., Michaud, E.J., Kadwell, S. H., Patel, I. R., and Wilkison, W. O. (1995) Agouti regulation of intracellular calcium: role in the insulin resistance of viable yellow mice. Proc. Natl. Acad. Sci. USA 92, 4733-4737
6. Jones, B. H., Kim, J. H., Zemel, M. B., Woychik, R. P., Michaud, E. J., Wilkison, W. O., and Moustaid, N. (1996) Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity. Am. J. Physiol. 270, E192-E196
7. 2+-dependent mechanism. FASEB J. 12, 1391-1396
8. Ashcroft, S. J. H., and Ashcroft, F. M. (1990) Cell. Signal. 2, 197
9. Sturgess, N. C., Ashford, M. L. J., Cook, D. L., and Hales, C. N. (1985) The sulfonylurea receptor may be an ATP-sensitive potassium channel. Lancet 2, 474
10. Bryan, L. A., Nichols, C. G., Wechsler, S. W., Clement, J. P., Boyd, A. E., Gonzalez, G., Sosa, H. H., Nguy, K., Bryan, J., and Nelson, D. A. (1995) Cloning of the β cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science 268, 423-426
11. Alemzadeh, R, Slonlm, A. E., Zdanowicz, M. M., and Maturo, J. (1993) Modification of insulin resistance by diazoxide in obese Zucker rats. Endocrinology 133, 705-712
12. Alemzadeh, R., Jacobs, A. W., and Pitukcheewnont, P. (1996) Antiobesity effect of diazoxide in obese Zucker rats. Metabolism 45, 334-341
13. Alemzadeh, R., Langley, G., Upchurch, L., Smith, P., and Slonim, A. E. (1998) Beneficial effect of diazoxide in obese hyperinsulinemic adults. J. Clin. Endocr. Metab. 83, 1911-1915
14. Moustaid, N., Jones, B. H., and Taylor, J. W. (1996) Insulin increases lipogenic enzyme activity in cultured human adipocytes. J. Nutr. 126, 865-870
15. Jones, B. H., Standridge, M. K., and Moustaid, N. (1997) Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. Endocrinology 138, 1512-1517
16. 2+ concentration in isolated rat adipocytes. Diabetes 36, 174-177
17. 2+ indicators with greatly improved fluorescent properties. J. Biol. Chem. 260, 3440-3450
18. Kwon, H. Y., Bultman, S. J., Loffeler, C., Chen, W., Furdon, P. J., Powell, J. G., A. L. Usala, Wilkison, W. O., Hansmann, I., and Woychik, R. P. (1994) Molecular structure and mapping of the human homolog of the agouti gene. Proc. Natl. Acad. Sci. USA 91, 9760-9764
19. Boobis, L. H., and Manghan, R. J. (1983) A simple one-step enzymatic fluorometric method for the determination of glycerol in 20 μ1 of plasma. Clin. Chim. Acta 132, 173-179
20. +-channels in mouse pancreatic β-cells. Proc. R. Soc. London Ser. B 243, 139-144
21. 2+ as evidenced in single pancreatic islets. J. Biol. Chem. 268, 22265-22268
22. + channels: paradigm lost, paradigm regained. Science 270, 1159
23. Thomas, P. M., Cote, G. J., Wohllk, N., Haddad, B., Mathew, P. M., Rabl, W., Bryan, L. A., Gagel, R. F., and Bryan, J. (1995) Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science 268, 426-429
24. Jacobs, D. B., and Jung, C. Y. (1985) Sulfonylurea potentiates insulin-induced recruitment of glucose transport carrier in rat adipocytes. J. Biol. Chem. 260, 2593-2596
25. Martz, A., Jo, I., and Jung, C. Y. (1998) Sulfonylurea binding to adipocyte membrane and potentiation of insulin stimulated hexose transport. J. Biol. Chem. 264, 13672-13678
26. Rajan, A. S., Zhao, L. T., Barbara, K. B., John, P. C., Samuel, W. C., and Aubrey, E. B. (1994) Do adipocytes contain high affinity sulfonylurea receptor? Endocrinology 134, 1581-1588
27. Maloff, B. L., and Lockwood, D. H. (1981) In vitro effects of a sulfonylurea on insulin action in adipocytes. J. Clin. Invest. 68, 85-90
28. Muller, G., and Geisen, K. (1996) Characterization of the molecular mode of action of the sulfonylurea, glimepiride at adipocytes. Horm. Metab. Res. 28, 469-487
29. Muller, G., Wied, S., Wetekam, E-M., Crecelius, A., Unkelbach, A., and Punter, J. (1994) Stimulation of glucose utilization in 3T3-L1 adipocytes and rat diaphragm in vitro by the sulfonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade. Biochem. Pharmacol. 48, 985-996
30. KATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270, 1167-1170
31. Chagnon, Y. C., Perusse, L., and Boochard, C. (1998) The human obesity gene map: the 1997 update. Obesity Res. 6, 76-92
32. Hani, E. H., Clement, K., Velho, G., Vionnet, N., Hager, J., Philippi, A., Dida, L., Inove, H., Permott, M. A., Basdevant, A., North, M., Demenais, F., Guy-Grand, M., and Frogvel, P. (1997) Genetic studies of the sulfonylurea receptor gene locus in NIDDM and in morbid obesity among French Caucasians. Diabetes. 46, 688-694