The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans

Current Biology

Volumn 11, Issue 19, 2001, Pages 1517-1523

  Murakami, Shin ^a,b,c   Johnson, Thomas E ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROPERTIES AND PARAMETERS; GENE EXPRESSION; GENETIC REGULATION; LIFESPAN; LONGEVITY; METABOLIC REGULATION; PHOSPHATIDYLINOSITOL KINASE; PROTEIN TYROSINE KINASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRESS TOLERANCE; TRANSCRIPTION FACTOR;

CAENORHABDITIS ELEGANS;

EID: 0035797913     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00453-5     Document Type: Article

References (38)

1. Genetic analysis of aging: Role of oxidative damage and environmental stresses
2. Aging of C. elegans - Mosaics and mechanisms
3. Nematode aging: Putting metabolic theories to the test
4. Molecular genetic mechanisms of life span manipulation in Caenorhabditis elegans
5. daf-16: An HNF-3-forkhead family member that can function to double the lifespan of Caenorhabditis elegans
6. The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in Caenorhabditis elegans
7. Determination of life-span in Caenorhabditis elegans by four clock genes
8. Cell nonautonomy of Caenorhabditis elegans daf-2 function in the regulation of diapause and life span
9. The spe-10 mutant has longer life and increases stress resistance
10. A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
11. Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
12. Oxidative stress and aging in Caenorhabditis elegans
13. Aging and resistance to oxidative damage in Caenorhabditis elegans
14. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
15. Life extension and stress resistance in Caenorhabditis elegans modulated by the old-1 gene
16. Genes that regulate both development and longevity in Caenorhabditis elegans
17. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
18. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
19. Paralogy and orthology of tyrosine kinases that can extend the life span of Caenorhabditis elegans
20. Extended life-span and stress resistance in the Drosophila mutant methuselah
21. Resistance to environmental stress in Drosophila melanogaster selected for postponed senescence
22. Cloning and characterization of seven human forkhead proteins: Binding site specificity and DNA bending
23. Neurosecretory control of aging in Caenorhabditis elegans
24. Signals from the reproductive system regulate the lifespan of C. elegans
25. Regulation of life span in model organisms
26. Oxidative stress, caloric restriction, and aging
27. What is hormesis and why haven't we heard about it before?
28. Chaperoning extended life
29. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
30. The p66shc adaptor protein controls oxidative stress response and life span in mammals
31. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
32. A PDK homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
33. A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-c and clk-1 mutants
34. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
35. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
36. Genetics of increased and retarded aging in mice