A model for binding of structurally diverse natural product inhibitors of protein phosphatases PP1 and PP2A

Journal of Medicinal Chemistry

Volumn 40, Issue 20, 1997, Pages 3199-3206

  Gupta, Varsha ^a   Ogawa, Anthony K ^a   Du, Xiaohui ^a   Houk, K N ^a   Armstrong, Robert W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALYCULIN A; CALYCULIN C; CYANOGINOSIN; NATURAL PRODUCT; NODULARIN; OKADAIC ACID; PHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; TAUTOMYCIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG BINDING; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; STRUCTURE ACTIVITY RELATION;

ANTIBIOTICS, ANTIFUNGAL; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; MICROCYSTINS; MODELS, MOLECULAR; OKADAIC ACID; OXAZOLES; PEPTIDES, CYCLIC; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN BINDING; PROTEIN CONFORMATION; PYRANS; SIGNAL TRANSDUCTION; SPIRO COMPOUNDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TOXINS, BIOLOGICAL;

EID: 0030806027     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960873x     Document Type: Article

References (58)

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