-
1
-
-
0027017178
-
Induction of apoptosis - New targets for cancer chemotherapy
-
Dive C, Evans CA, Whetton AD. Induction of apoptosis - New targets for cancer chemotherapy. Semin Cancer Biol 1992; 3: 417-427.
-
(1992)
Semin Cancer Biol
, vol.3
, pp. 417-427
-
-
Dive, C.1
Evans, C.A.2
Whetton, A.D.3
-
2
-
-
0030999750
-
Apoptosis and the dilemma of cancer chemotherapy
-
Hannun YA. Apoptosis and the dilemma of cancer chemotherapy. Blood 1997; 89: 1845-1853.
-
(1997)
Blood
, vol.89
, pp. 1845-1853
-
-
Hannun, Y.A.1
-
3
-
-
0030762122
-
Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
-
Los M, Herr I, Friesen C, Fulda S, Schulze-Osthoff K, Debatin KM. Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases). Blood 1997; 90: 3118-3129.
-
(1997)
Blood
, vol.90
, pp. 3118-3129
-
-
Los, M.1
Herr, I.2
Friesen, C.3
Fulda, S.4
Schulze-Osthoff, K.5
Debatin, K.M.6
-
4
-
-
0029935682
-
Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C, Herr I, Krammer PH, Debatin KM. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 1996; 2: 574-577.
-
(1996)
Nat Med
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
5
-
-
0031032294
-
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
-
Decaudin D, Geley S, Hirsch T, et al. Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 1997; 57: 62-67.
-
(1997)
Cancer Res
, vol.57
, pp. 62-67
-
-
Decaudin, D.1
Geley, S.2
Hirsch, T.3
-
6
-
-
0030843575
-
Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
-
Kim CN, Wang X, Huang Y, et al. Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res 1997; 57: 3115-3120.
-
(1997)
Cancer Res
, vol.57
, pp. 3115-3120
-
-
Kim, C.N.1
Wang, X.2
Huang, Y.3
-
7
-
-
0035525733
-
Cellular stress response and apoptosis in cancer therapy
-
Herr I, Debatin KM. Cellular stress response and apoptosis in cancer therapy. Blood 2001; 98: 2603-2614.
-
(2001)
Blood
, vol.98
, pp. 2603-2614
-
-
Herr, I.1
Debatin, K.M.2
-
8
-
-
0034669944
-
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
-
Genini D, Adachi S, Chao Q, et al. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood 2000; 96: 3537-3543.
-
(2000)
Blood
, vol.96
, pp. 3537-3543
-
-
Genini, D.1
Adachi, S.2
Chao, Q.3
-
9
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
Kuida K, Haydar TF, Kuan CY, et al. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 1998; 94: 325-337.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
-
10
-
-
0033582526
-
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
-
Sun XM, MacFarlane M, Zhuang J, Wolf BB, Green DR, Cohen GM. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem 1999; 274: 5053-5060.
-
(1999)
J Biol Chem
, vol.274
, pp. 5053-5060
-
-
Sun, X.M.1
MacFarlane, M.2
Zhuang, J.3
Wolf, B.B.4
Green, D.R.5
Cohen, G.M.6
-
11
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. Embo J 1998; 17: 1675-1687.
-
(1998)
Embo J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
-
12
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 1996; 86: 147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
13
-
-
0034613302
-
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1
-
Jiang X, Wang X. Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. J Biol Chem 2000; 275: 31199-31203.
-
(2000)
J Biol Chem
, vol.275
, pp. 31199-31203
-
-
Jiang, X.1
Wang, X.2
-
14
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
15
-
-
0033529634
-
Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex
-
Cain K, Brown DG, Langlais C, Cohen GM. Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex. J Biol Chem 1999; 274: 22686-22692.
-
(1999)
J Biol Chem
, vol.274
, pp. 22686-22692
-
-
Cain, K.1
Brown, D.G.2
Langlais, C.3
Cohen, G.M.4
-
16
-
-
0033596980
-
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
Zou H, Li Y, Liu X, Wang X. An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 1999; 274: 11549-11556.
-
(1999)
J Biol Chem
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
17
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem R, Hakem A, Duncan GS, et al. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 1998; 94: 339-352.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
-
18
-
-
0033580926
-
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
-
Saleh A, Srinivasula SM, Acharya S, Fishel R, Alnemri ES. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J Biol Chem 1999; 274: 17941-17945.
-
(1999)
J Biol Chem
, vol.274
, pp. 17941-17945
-
-
Saleh, A.1
Srinivasula, S.M.2
Acharya, S.3
Fishel, R.4
Alnemri, E.S.5
-
19
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
-
Slee EA, Harte MT, Kluck RM, et al. Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol 1999; 144: 281-292.
-
(1999)
J Cell Biol
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
-
20
-
-
0035065901
-
Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation
-
Cai Z, Lin M, Wuchter C, et al. Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation. Leukemia 2001; 15: 567-574.
-
(2001)
Leukemia
, vol.15
, pp. 567-574
-
-
Cai, Z.1
Lin, M.2
Wuchter, C.3
-
21
-
-
0033607006
-
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
Yin XM, Wang K, Gross A, et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 1999; 400: 886-891.
-
(1999)
Nature
, vol.400
, pp. 886-891
-
-
Yin, X.M.1
Wang, K.2
Gross, A.3
-
22
-
-
85047697158
-
Release of intact, monomenc cytochrome c from apoptotic and necrotic cells
-
Jemmerson R, LaPlante B, Treeful A. Release of intact, monomenc cytochrome c from apoptotic and necrotic cells. Cell Death Differ 2002; 9: 538-548.
-
(2002)
Cell Death Differ
, vol.9
, pp. 538-548
-
-
Jemmerson, R.1
LaPlante, B.2
Treeful, A.3
-
23
-
-
0035469830
-
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo
-
Renz A, Berdel WE, Kreuter M, Belka C, Schulze-Osthoff K, Los M. Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo. Blood 2001; 98: 1542-1548.
-
(2001)
Blood
, vol.98
, pp. 1542-1548
-
-
Renz, A.1
Berdel, W.E.2
Kreuter, M.3
Belka, C.4
Schulze-Osthoff, K.5
Los, M.6
-
24
-
-
0033593791
-
Altered cytochrome c display precedes apoptotic cell death in Drosophila
-
Varkey J, Chen P, Jemmerson R, Abrams JM. Altered cytochrome c display precedes apoptotic cell death in Drosophila. J Cell Biol 1999; 144: 701-710.
-
(1999)
J Cell Biol
, vol.144
, pp. 701-710
-
-
Varkey, J.1
Chen, P.2
Jemmerson, R.3
Abrams, J.M.4
-
25
-
-
0033596909
-
A conformational change in cytochrome c of apoptotic and necrotic cells is detected by monoclonal antibody binding and mimicked by association of the native antigen with synthetic phospholipid vesicles
-
Jemmerson R, Liu J, Hausauer D, Lam KP, Mondino A, Nelson RD. A conformational change in cytochrome c of apoptotic and necrotic cells is detected by monoclonal antibody binding and mimicked by association of the native antigen with synthetic phospholipid vesicles. Biochemistry 1999; 38: 3599-3609.
-
(1999)
Biochemistry
, vol.38
, pp. 3599-3609
-
-
Jemmerson, R.1
Liu, J.2
Hausauer, D.3
Lam, K.P.4
Mondino, A.5
Nelson, R.D.6
-
26
-
-
0025785221
-
Common structural features among monoclonal antibodies binding the same antigenic region of cytochrome c
-
Goshorn SC, Retzel E, Jemmerson R. Common structural features among monoclonal antibodies binding the same antigenic region of cytochrome c. J Biol Chem 1991; 266: 2134-2142.
-
(1991)
J Biol Chem
, vol.266
, pp. 2134-2142
-
-
Goshorn, S.C.1
Retzel, E.2
Jemmerson, R.3
-
27
-
-
0030589359
-
Maturation of the antibody response to the major epitope on the self antigen mouse cytochrome c. Restricted V gene usage, selected mutations, and increased affinity
-
Mueller CM, Jemmerson R. Maturation of the antibody response to the major epitope on the self antigen mouse cytochrome c. Restricted V gene usage, selected mutations, and increased affinity. J Immunol 1996; 157: 5329-5338.
-
(1996)
J Immunol
, vol.157
, pp. 5329-5338
-
-
Mueller, C.M.1
Jemmerson, R.2
-
28
-
-
9344261615
-
The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism
-
Martin SJ, Amarante-Mendes GP, Shi L, et al. The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism. Embo J 1996; 15: 2407-2416.
-
(1996)
Embo J
, vol.15
, pp. 2407-2416
-
-
Martin, S.J.1
Amarante-Mendes, G.P.2
Shi, L.3
-
29
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102: 33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
30
-
-
0037134495
-
Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria
-
Guo Y, Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES. Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria. J Biol Chem 2002; 277: 13430-13437.
-
(2002)
J Biol Chem
, vol.277
, pp. 13430-13437
-
-
Guo, Y.1
Srinivasula, S.M.2
Druilhe, A.3
Fernandes-Alnemri, T.4
Alnemri, E.S.5
-
31
-
-
0036141029
-
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
-
Deng Y, Lin Y, Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev 2002; 16: 33-45.
-
(2002)
Genes Dev
, vol.16
, pp. 33-45
-
-
Deng, Y.1
Lin, Y.2
Wu, X.3
-
32
-
-
0035476255
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria
-
Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Cancer Res 2001; 61: 7339-7348.
-
(2001)
Cancer Res
, vol.61
, pp. 7339-7348
-
-
Zhang, X.D.1
Zhang, X.Y.2
Gray, C.P.3
Nguyen, T.4
Hersey, P.5
-
33
-
-
0037192790
-
Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein
-
Sun XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM. Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. J Biol Chem 2002; 277: 11345-11351.
-
(2002)
J Biol Chem
, vol.277
, pp. 11345-11351
-
-
Sun, X.M.1
Bratton, S.B.2
Butterworth, M.3
MacFarlane, M.4
Cohen, G.M.5
-
34
-
-
0037273845
-
Death receptors leave a caspase footprint that Smacs of XIAP
-
Bratton SB, Cohen GM. Death receptors leave a caspase footprint that Smacs of XIAP. Cell Death Differ 2003; 10: 4-6.
-
(2003)
Cell Death Differ
, vol.10
, pp. 4-6
-
-
Bratton, S.B.1
Cohen, G.M.2
-
35
-
-
0032529676
-
Cytochrome c induces caspase-dependent apoptosis in intact hematopoietic cells and overrides apoptosis suppression mediated by bcl-2, growth factor signaling, MAP-kinase-kinase, and malignant change
-
Garland JM, Rudin C. Cytochrome c induces caspase-dependent apoptosis in intact hematopoietic cells and overrides apoptosis suppression mediated by bcl-2, growth factor signaling, MAP-kinase-kinase, and malignant change. Blood 1998; 92: 1235-1246.
-
(1998)
Blood
, vol.92
, pp. 1235-1246
-
-
Garland, J.M.1
Rudin, C.2
-
36
-
-
0033120803
-
Nitric-oxide-induced apoptosis in human leukemic lines requires mi tochondrial lipid degradation and cytochrome C release
-
Ushmorov A, Ratter F, Lehmann V, Droge W, Schirrmacher V, Umansky V. Nitric-oxide-induced apoptosis in human leukemic lines requires mi tochondrial lipid degradation and cytochrome C release. Blood 1999; 93: 2342-2352.
-
(1999)
Blood
, vol.93
, pp. 2342-2352
-
-
Ushmorov, A.1
Ratter, F.2
Lehmann, V.3
Droge, W.4
Schirrmacher, V.5
Umansky, V.6
-
37
-
-
0035895056
-
Receptor-and mitochondrial-mediated apoptosis in acute leukemia: A translational view
-
Schimmer AD, Hedley DW, Penn LZ, Minden MD. Receptor-and mitochondrial-mediated apoptosis in acute leukemia: A translational view. Blood 2001; 98: 3541-3553.
-
(2001)
Blood
, vol.98
, pp. 3541-3553
-
-
Schimmer, A.D.1
Hedley, D.W.2
Penn, L.Z.3
Minden, M.D.4
-
38
-
-
0034897315
-
Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells
-
Ito Y, Mishra NC, Yoshida K, Kharbanda S, Saxena S, Kufe D. Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells. Cell Death Differ 2001; 8: 794-800.
-
(2001)
Cell Death Differ
, vol.8
, pp. 794-800
-
-
Ito, Y.1
Mishra, N.C.2
Yoshida, K.3
Kharbanda, S.4
Saxena, S.5
Kufe, D.6
-
39
-
-
0032032270
-
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3
-
Amarante-Mendes GP, Naekyung Kim C, Liu L, et al. Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3. Blood 1998; 91: 1700-1705.
-
(1998)
Blood
, vol.91
, pp. 1700-1705
-
-
Amarante-Mendes, G.P.1
Naekyung Kim, C.2
Liu, L.3
-
40
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 2001; 292: 727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
-
41
-
-
0035880232
-
Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells
-
Jia L, Srinivasula SM, Liu FT, et al. Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells. Blood 2001; 98: 414-421.
-
(2001)
Blood
, vol.98
, pp. 414-421
-
-
Jia, L.1
Srinivasula, S.M.2
Liu, F.T.3
-
42
-
-
0037079699
-
Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release
-
Chandra J, Mansson E, Gogvadze V, Kaufmann SH, Albertioni F, Orrenius S. Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release. Blood 2002; 99: 655-663.
-
(2002)
Blood
, vol.99
, pp. 655-663
-
-
Chandra, J.1
Mansson, E.2
Gogvadze, V.3
Kaufmann, S.H.4
Albertioni, F.5
Orrenius, S.6
-
43
-
-
0035525748
-
Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria
-
Cuvillier O, Levade T. Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria. Blood 2001; 98: 2828-2836.
-
(2001)
Blood
, vol.98
, pp. 2828-2836
-
-
Cuvillier, O.1
Levade, T.2
-
44
-
-
0034844509
-
Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex
-
Almond JB, Snowden RT, Hunter A, Dinsdale D, Cain K, Cohen GM. Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex. Leukemia 2001; 15: 1388-1397.
-
(2001)
Leukemia
, vol.15
, pp. 1388-1397
-
-
Almond, J.B.1
Snowden, R.T.2
Hunter, A.3
Dinsdale, D.4
Cain, K.5
Cohen, G.M.6
|