The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and -metabolizing enzymes in mice

Drug Metabolism and Disposition

Volumn 34, Issue 3, 2006, Pages 405-409

  Anapolsky, Alexander ^a   Teng, Shirley ^a   Dixit, Santosh ^b   Piquette Miller, Micheline ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANION TRANSPORT PROTEIN; BETA ACTIN; BREAST CANCER RESISTANCE PROTEIN; CORN OIL; CYTOCHROME P450 1A2; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; DRUG METABOLIZING ENZYME; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; N (2 FLUORENYL)ACETAMIDE; PREGNANE X RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TRANSPORT; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER; MOUSE; MOUSE MUTANT; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; STRAIN DIFFERENCE; WILD TYPE;

2-ACETYLAMINOFLUORENE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HUMANS; LIVER; METABOLIC DETOXICATION, DRUG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID;

ANIMALIA; ZEA MAYS;

EID: 33344477070     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.105.006197     Document Type: Article

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