Knocking down PML impairs p53 signaling transduction pathway and suppresses irradiation induced apoptosis in breast carcinoma cell MCF-7

Journal of Cellular Biochemistry

Volumn 97, Issue 3, 2006, Pages 561-571

  Tian, Bao Lei ^a   Mei, Zhu Zhong ^a   Song, Yi ^a   Qian, Jun Jie ^a   Dong, Yan ^a   Liu, Hua ^a   Liu, Bin ^a   Zhao, Guo Wei ^a   Sun, Zhi Xian ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

Apoptosis; Irradiation; MCF 7; MDM2; p53; PML; RNAi

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; MESSENGER RNA; PROTEASOME; PROTEIN BAX; PROTEIN MDM2; PROTEIN P53; UBIQUITIN;

ACETYLATION; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CELL CYCLE ARREST; CELL STRAIN MCF 7; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IRRADIATION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; COBALT RADIOISOTOPES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOWN-REGULATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUCIFERASES; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-MDM2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN;

MINK CELL FOCUS-FORMING VIRUS;

EID: 33244476998     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20584     Document Type: Article

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