(Carboxyalkyl)benzyl propargyl ethers as selective inhibitors of leukocyte-type 12-lipoxygenases

Journal of Medicinal Chemistry

Volumn 39, Issue 25, 1996, Pages 4871-4878

  Gorins, Gilles ^a   Kuhnert, Lethea ^b   Johnson, Carl R ^a   Marnett, Lawrence J ^b  

^a WAYNE STATE UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [4 [(2 TRIDECYNYLOXY)METHYL]PHENYL]PROPANOIC ACID; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONIC ACID; BENZOIC ACID DERIVATIVE; ETHER DERIVATIVE; LIPOXYGENASE INHIBITOR; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CELL PROLIFERATION; DOSE RESPONSE; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKOCYTE; METASTASIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; SWINE; THROMBOCYTE AGGREGATION;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; HUMANS; LEUKOCYTES; LIPOXYGENASE INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; PARGYLINE; RABBITS; SPECTROPHOTOMETRY, INFRARED; SWINE;

EID: 0029770071     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9606047     Document Type: Article

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