A model of arachidonic acid binding for 15-lipoxygenase

Advances in Experimental Medicine and Biology

Volumn 433, Issue , 1997, Pages 435-438

  Gan, Qing Fen ^a   Sigal, Elliott ^a   Browner, Michelle F ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; ENZYME BINDING; ENZYME INACTIVATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; LIGAND BINDING; NONHUMAN; OXYGENATION; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALIA;

EID: 0031392653     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4899-1810-9_96     Document Type: Article

References (6)

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2. Lewis RA, Austen KF. Soberman RJ; Leukotrienes and other products of the 5-lipoxygenase pathway: biochemistry and relation to pathobiology in human diseases. N. Engl. J. Med. 1990; 323: 645-655.
3. Kühn H, Sprecher H, Brash AR; On singular or dual positional specificity of lipoxygenases, J. Biol. Chem. 265:16300 (1990).
4. Can QF, Witkop GL, Sloane DL., Straub KM, Sigal E; Identification of a specific methionine in mammalian 15-lipoxygenase which is oxygenated by the enzyme product 13-HPODE: dissociation of sulfoxide formation from self-inactivation. Biochemistry 34:7069 (1995).
5. Boyington JC, Gaffney BJ, Amzel LM; The three-dimensional structure of an arachidonic acid 15-lipoxygenase. Science 260:1482 (1993).
6. Minor W, Steczko J, Bolin JT, Otwinowski Z, Axelrod B; Crystallographic determination of the active site iron and its ligands in soybean lipoxygenase L-1, Biochemistry 32:6320 (1993).