A specific 15-lipoxygenase inhibitor limits the progression and monocyte-macrophage enrichment of hypercholesterolemia-induced atherosclerosis in the rabbit

Atherosclerosis

Volumn 136, Issue 2, 1998, Pages 203-216

  Bocan, Thomas M A ^a   Rosebury, Wendy S ^a   Mueller, Sandra Bak ^a   Susan Kuchera, ^a   Welch, Kathryn ^a   Daugherty, Alan ^b   Cornicelli, Joseph A ^a  

^a PFIZER INC   (United States)

^b Cardiovascular Division   (United States)

Author keywords

15 lipoxygenase; Atherosclerosis; Macrophages; Oxidant signalling

Indexed keywords

ARACHIDONATE 15 LIPOXYGENASE; ARACHIS OIL; CHOLESTEROL; CHOLESTEROL ESTER; COCONUT OIL; LIPOPROTEIN; LIPOXYGENASE INHIBITOR; PD 146176; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; ENZYME INHIBITION; FAT INTAKE; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; LIPID PEROXIDATION; MACROPHAGE; MALE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; AORTA, THORACIC; ARACHIDONATE 15-LIPOXYGENASE; ARTERIOSCLEROSIS; CHOLESTEROL; CHOLESTEROL ESTERS; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMORAL ARTERY; FLUORENES; HYPERCHOLESTEROLEMIA; ILIAC ARTERY; IMMUNOHISTOCHEMISTRY; LIPOXYGENASE INHIBITORS; MACROPHAGES; MALE; MONOCYTES; PHOSPHOLIPIDS; RABBITS;

EID: 0032006236     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(97)00204-9     Document Type: Article

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