Synthesis and biological activities of novel antiallergic agents with 5- lipoxygenase inhibiting action

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 2, 2000, Pages 373-380

  Nakano, Hiroyuki ^a   Inoue, Tsutomu ^a   Kawasaki, Nobuhide ^b   Miyataka, Hideki ^b   Matsumoto, Hitoshi ^b   Taguchi, Takeo ^c   Inagaki, Naoki ^d   Nagai, Hiroichi ^d   Satoh, Toshio ^b  

^a Fuji Yakuhin Co Ltd   (Japan)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^d GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Allergies; Antagonists; Antioxidants; Enzyme inhibitors

Indexed keywords

1 [2 [2 (4 HYDROXY 2,3,5 TRIMETHYLPHENOXY)ETHOXY]ETHYL] 2 (4 METHYL 1 HOMOPIPERIRAZINO) 1H BENZIMIDAZOLE DIFUMARATE; ANTIALLERGIC AGENT; ARACHIDONATE 5 LIPOXYGENASE; BENZIMIDAZOLE DERIVATIVE; BOM 1006; HISTAMINE; UNCLASSIFIED DRUG;

ALLERGY; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SYNTHESIS; GUINEA PIG; HISTAMINE RELEASE; MALE; MAST CELL LEUKEMIA; NONHUMAN; PERITONEUM MAST CELL; RAT;

ANIMALS; ANTI-ALLERGIC AGENTS; ARACHIDONATE 5-LIPOXYGENASE; ENZYME INHIBITORS; GUINEA PIGS; HISTAMINE RELEASE; ILEUM; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MAST CELLS; MICROSOMES, LIVER; MUSCLE CONTRACTION; RATS; RATS, WISTAR; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0034005413     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00291-6     Document Type: Article

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