Tryptophan 500 and arginine 707 define product and substrate active site binding in soybean lipoxygenase-1

Biochemistry

Volumn 43, Issue 41, 2004, Pages 13063-13071

  Ruddat, Viola C ^a   Mogul, Rakesh ^a   Chorny, Ilya ^b   Chen, Cameron ^a   Perrin, Noah ^a   Whitman, Stephanie ^a   Kenyon, Victor ^a   Jacobson, Matthew P ^b   Bernasconi, Claude F ^a   Holman, Theodore R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; CARBOXYLATION; CARBOXYLIC ACIDS; MUTAGENESIS;

STEADY-STATE KINETICS; STOPPED-FLOW KINETICS;

FATTY ACIDS;

13 HYDROPEROXY 9,11 OCTADECADIENOIC ACID; 15 HYDROPEROXYARACHIDONIC ACID; ARACHIDONIC ACID; ARACHIDONIC ACID DERIVATIVE; ARGININE; ISOENZYME; LINOLEIC ACID; LIPOXYGENASE; LIPOXYGENASE I; STEARIC ACID DERIVATIVE; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME SUBSTRATE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SOYBEAN;

ARGININE; BINDING SITES; CATALYSIS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DEUTERIUM EXCHANGE MEASUREMENT; ENZYME ACTIVATION; KINETICS; LEUKOTRIENES; LIGANDS; LINOLEIC ACIDS; LIPID PEROXIDES; LIPOXYGENASE; PROTEIN BINDING; SOYBEANS; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

GLYCINE MAX;

EID: 5444269066     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0489098     Document Type: Article

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