Structure-activity relationships of pyrimido-pyrimidine series of 5-lipoxygenase inhibitors

Medicinal Chemistry Research

Volumn 6, Issue 1, 1996, Pages 61-67

  Basha, Anwer ^a   Ratajczyk, James D ^a   Dyer, Richard D ^a   Young, Patrick ^a   Carter, George W ^a   Brooks, Clint D W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0007398924     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Samuelsson, B. Science 1983, 220, 568.
2. Lewis, R. A.; Austen, F.; Soberman, R.J. New Engl. J. Med. 1990, 323, 645.
3. Brooks, D. W.; Carter, G. W. The Discovery of Zileuton, in " The Search for Anti-Inflammatory Drugs", Merluzzi, V.J., Adams, J., eds., Birkhaüser, Boston, 1995, pp129-160.
4. Gresele, P.; Zoga, C.; Deckmyn, H.; Anout, J.; Vermylen, J.; Verstraete, M. Throm. Haemostas 1983, 50, 852.
5. Carter, G.W. et al. Fed. Proc. 1985, 44, 904.
6. Fischer, F, G.; Roch, J.; Neumann, W. P. Liebigs Ann. Chem. 1960, 631, 147.
7. Brooks, D. W.; Basha, A. U.S. Patent 4,963,541; Oct. 16, 1990.
8. Carter, G. W.; Young, P. R.; Albert, D. H.; Bouska, J.; Dyer, R.; Bell, R. L.; Summers, J. B.; Brooks, D. W. J. Pharmacol. Exp. Ther. 1991, 256, 929-937.