Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 5, 2005, Pages 1435-1440

  Weinstein, David S ^a   Liu, Wen ^a   Gu, Zhengxiang ^a   Langevine, Charles ^a   Ngu, Khehyong ^a   Fadnis, Leena ^a   Combs, Donald W ^a   Sitkoff, Doree ^a   Ahmad, Saleem ^a   Zhuang, Shaobin ^a   Chen, Xing ^a   Wang, Feng Lai ^a   Loughney, Deborah A ^a   Atwal, Karnail S ^a   Zahler, Robert ^a   Macor, John E ^a   Madsen, Cort S ^a   Murugesan, Natesan ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

15 Lipoxygenase inhibitors; Arachadonic acid; Homotryptamine; Linoleic acid; Sulfonamides; Tryptamine

Indexed keywords

ARACHIDONATE 15 LIPOXYGENASE; LIPOXYGENASE INHIBITOR; SULFONAMIDE; TRYPTAMINE; TRYPTAMINE DERIVATIVE;

ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; ENZYME INHIBITION; ENZYME ISOLATION;

MAMMALIA; SIGANUS;

EID: 13944274447     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.12.081     Document Type: Article

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